Oncogenic Roles of the PI3K/AKT/mTOR axis

Cited by (358)

Items 201–300 of 358

1. Autophagy in gastrointestinal cancers
   Bo‐Zong Shao, Ningli Chai, Yi Yao, Jinping Li, Hkw Law, Enqiang Linghu · 2022 · Frontiers in Oncology
2. Cryogenic 3D Printing of ß-TCP/PLGA Composite Scaffolds Incorporated With BpV (Pic) for Treating Early Avascular Necrosis of Femoral Head
   Li Feng, Zhifu Cao, Kai Li, Ke Huang, Chengliang Yang, Ye Li, Chuanchuan Zheng, Yulu Ye, Tingjie Zhou, Haoqiang Peng et al. · 2022 · Frontiers in Bioengineering and Biotechnology
3. Artesunate attenuates the tumorigenesis of choroidal melanoma via inhibiting EFNA3 through Stat3/Akt signaling pathway
   Ningning Yao, Qingyue Ma, Wendan Yi, Yuanzhang Zhu, Yichong Liu, Xiaodi Gao, Qian Zhang, Wenjuan Luo · 2024 · Journal of Cancer Research and Clinical Oncology
4. BRD9 promotes the progression of gallbladder cancer via CST1 upregulation and interaction with FOXP1 through the PI3K/AKT pathway and represents a therapeutic target
   Jing Qiang, Cheng Zhao, Liu-Qing Shi, Si-Rui Sun, Hua-Kai Wang, Shilei Liu, Ziyi Yang, Ping Dong, Shanshan Xiang, Jiandong Wang et al. · 2024 · Gene Therapy
5. Bioinformatics Analysis of the Expression of Key Long Intergenic Non-Protein Coding RNA Genes in Bladder Cancer
   Yun‐Zhi Lin, Yu‐Peng Wu, Zhi‐Bin Ke, Hai Cai, Dong‐Ning Chen, Shao‐Hao Chen, Xiaodong Li, Tingting Lin, Jin‐Bei Huang, Qing‐Shui Zheng et al. · 2020 · Medical Science Monitor
6. The Role of Kallikrein 7 in Tumorigenesis
   Fengyi Xiang, Yueqing Wang, Chunyu Cao, Qingyun Li, Hao Deng, Jun Zheng, Xiaowen Liu, Xiao Tan · 2021 · Current Medicinal Chemistry
7. MicroRNA‑23b‑3p targets non‑SMC condensing I complex subunit G to promote proliferation and inhibit apoptosis of colorectal cancer cells via regulation of the PI3K/AKT signaling pathway
   Peidong Li, Jing Wen, Xiru Ren, Yu Zhou, Yuan Xue, Zaihua Yan, Shengjie Li, Hongpeng Tian, Xuegui Tang, Guang-Jun Zhang · 2021 · Oncology Letters
8. Circular RNA SET domain protein 3 promotes nasopharyngeal carcinoma proliferation, cisplatin resistance, and protein kinase B / mammalian target of rapamycin pathway activation by modulating microRNA-147a expression
   Gang Deng, Fei Wang, YiSa Song · 2022 · Bioengineered
9. DZW-310, a novel phosphoinositide 3-kinase inhibitor, attenuates the angiogenesis and growth of hepatocellular carcinoma cells via PI3K/AKT/mTOR axis
   Yuting Wu, Xiangbo Xu, Mingyue Liu, Xiaochun Qin, Qiong Wu, Huaiwei Ding, Qingchun Zhao · 2022 · Biochemical Pharmacology
10. Advances in the Study of Bioactive Nanoparticles for the Treatment of HCC and Its Postoperative Residual Cancer
    Yanxu Li, Hao Zou, Zekun Zheng, Zhuoheng Liu, Huiyuan Hu, Wei Wu, Tao Wang · 2023 · International Journal of Nanomedicine
11. Ovarian squamous cell carcinoma associated with teratoma: a report of six cases with genomic analysis
    Yun Liang, Huajuan Ruan, Minghua Yu, Bingjian Lü · 2023 · Pathology
12. miR‑541‑3p inhibits the viability and migration of vascular smooth muscle cells via targeting STIM1
    Zhiyu Lv, Dengliang Yi, Chi Zhang, Yujie Xie, He Huang, Zhongcai Fan, Xing Liu · 2021 · Molecular Medicine Reports
13. The Emerging Role of Long Non-Coding RNAs in Esophageal Cancer: Functions in Tumorigenesis and Clinical Implications
    Yali Han, Guo Zhao, Xinhang Shi, Yu‐Shan Wang, Xin Wen, Lu Zhang, Xiangqian Guo · 2022 · Frontiers in Pharmacology
14. Discussion on the Mechanism of Gandoufumu Decoction Attenuates Liver Damage of Wilson’s Disease by Inhibiting Autophagy through the PI3K/Akt/mTOR Pathway Based on Network Pharmacology and Experimental Verification
    Lulu Tang, Chenling Zhao, Jing Zhang, Ting Dong, Huaizhen Chen, Taohua Wei, Jiuxiang Wang, Wenming Yang · 2023 · Mediators of Inflammation
15. Promising antitumor effects of the curcumin analog DMC-BH on colorectal cancer cells
    Gang Liu, Jian Chen, Zhicheng Bao · 2023 · Aging
16. The molecular mechanism of ginsenoside Rh2 and its octyl ester derivative on anti-angiogenesis in cancer treatment: The battle between PI3K and ROS
    Qi‐rui Hu, Xin-Yi Zhong, Hua Feng, Xu-Chu Li, Zhihong Zhang, Yao Pan, Ting F Luo, Zeyuan Deng, Fang Chen · 2025 · Journal of Ginseng Research
17. Isofraxidin Inhibits Receptor Activator of Nuclear Factor-κB Ligand–Induced Osteoclastogenesis in Bone Marrow–Derived Macrophages Isolated from Sprague–Dawley Rats by Regulating NF-κB/NFATc1 and Akt/NFATc1 Signaling Pathways
    Wei Wang, Bo Wang · 2021 · Cell Transplantation
18. miR-125a attenuates the malignant biological behaviors of cervical squamous cell carcinoma cells through Rad51
    Zeping Liu, Jinchang Huang, Qiuju Jiang, Xiaoling Li, Xiaohui Tang, Shasha Chen, Liling Jiang, Genghua Fu, Sijun Liu · 2022 · Bioengineered
19. DDR1 promotes LoVo cell proliferation by regulating energy metabolism
    Bin Xiong, Zehui Xie, Feixue Song, Huiling Chen, Xiaojuan Wang, Zhengxu Jin, Tiyun Han, Yi Li, Dekui Zhang · 2022 · Acta Biochimica et Biophysica Sinica
20. Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer
    Yaoxiang Tang, Jiadi Luo, Ying Zhou, Hongjing Zang, Yang Yang, Sile Liu, Hongmei Zheng, Jian Ma, Songqing Fan, Qiuyuan Wen · 2022 · BMC Cancer
21. SLC26A4 Mutation Promotes Cell Apoptosis by Inducing Pendrin Transfer, Reducing Cl- Transport, and Inhibiting PI3K/Akt/mTOR Pathway
    Xiang Dai, Jun Li, Xi‐Jiang Hu, Jian Ye, Wenqian Cai · 2022 · BioMed Research International
22. High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats
    Yanyan Sun, Xing Quan Zhu, Kaiyi Zhu, Jie Yu, Lin Cheng, Mingyan Hei · 2022 · International Journal of Medical Sciences
23. Protective role of exosomes derived from regulatory T cells against inflammation and apoptosis of BV-2 microglia under oxygen-glucose deprivation/reperfusion challenge
    Changqing Yang, Fei Yuan, Wan Shao, Lihong Yao, Shaoju Jin, Fangfang Han · 2022 · Genetics and Molecular Biology
24. Comprehensive analysis of cuproptosis-related lncRNAs in immune infiltration and prognosis in hepatocellular carcinoma
    Chunhua Liu, Simin Wu, Liying Lai, Jinyu Liu, Zhaofu Guo, Zegen Ye, Xiang 'Anthony' Chen · 2023 · BMC Bioinformatics
25. Carbon disulfide induces embryo loss by perturbing the expression of the mTOR signalling pathway in uterine tissue in mice
    Fengyan Huang, Yuan Sun, Han Gao, Hanbin Wu, Zhiping Wang · 2018 · Chemico-Biological Interactions
26. MicroRNA‐17‐3p protects against excessive posthypoxic autophagy in H9C2 cardiomyocytes via PTEN–Akt–mTOR signaling pathway
    Yi He, Dengwen Zhang, Qingqing Zhang, Yin Cai, Chongfeng Huang, Zhengyuan Xia, Sheng Wang · 2023 · Cell Biology International
27. Distinct mRNA expression profiles and miRNA regulators of the PI3K/AKT/mTOR pathway in breast cancer: insights into tumor progression and therapeutic targets
    Tomasz Sirek, Katarzyna Król-Jatręga, Przemysław Borawski, Nikola Zmarzły, Dariusz Boroń, Piotr Ossowski, Olga Nowotny-Czupryna, Kacper Boroń, Dominika Janiszewska-Bil, Elżbieta Mitka-Krysiak et al. · 2025 · Frontiers in Oncology
28. ZNF488 Promotes the Invasion and Migration of Pancreatic Carcinoma Cells through the Akt/mTOR Pathway
    Hongquan Qiu, Liang Zhang, Dongzhi Wang, Yu Xin Zhang, Hongyu Cai, Haiyan Miao, Feihu Chu · 2022 · Computational and Mathematical Methods in Medicine · Retracted
29. Roles of oncogenes in esophageal squamous cell carcinoma and their therapeutic potentials
    Shuai Xiao, Guo Cai Huang, Weihong Zeng, Jun Zhou, Yukun Li, Tingyu Fan, Xiaomin Liu, Jiliang Xia, Xi Zeng · 2022 · Clinical & Translational Oncology
30. Mechanisms of action of Fu Fang Gang Liu liquid in treating condyloma acuminatum by network pharmacology and experimental validation
    Zhu Fan, Shuxin Wang, Chenchen Xu, Jiao Yang, Bingnan Cui · 2023 · BMC Complementary Medicine and Therapies
31. Triple‑negative breast cancer cells that survive ionizing radiation exhibit an Axl‑dependent aggressive radioresistant phenotype
    Jianfeng Ji, Yuqin Ding, Yue Kong, Min Fang, Xiaofu Yu, Xiaojing Lai, Qing Gu · 2023 · Experimental and Therapeutic Medicine
32. Current and future perspectives on the regulation and functions of miR-545 in cancer development
    Jinze Shen, Xinming Su, Qurui Wang, Yufei Ke, Tianyu Zheng, Yunan Mao, Zehua Wang, Jingyin Dong, Shiwei Duan · 2023 · Cancer Pathogenesis and Therapy
33. Exploration of lncRNA/circRNA-miRNA-mRNA network in patients with chronic atrophic gastritis in Tibetan plateau areas based on DNBSEQ-G99 RNA sequencing
    Wen Pan, Chao Liu, Tao Ren, Xiaohong Chen, Cuiting Liang, Jin Wang, Jinlin Yang · 2024 · Scientific Reports
34. Diets enriched in PUFAs at an early postimplantation stage prevent embryo resorptions and impaired mTOR signaling in the decidua from diabetic rats
    Sabrina Lorena Roberti, Cintia Romina Gatti, Daiana Debora Fornes, Romina Higa, Alicia Jawerbaum · 2021 · The Journal of Nutritional Biochemistry
35. Updates of Genomics and Proteomics of Parathyroid Carcinoma
    Sung Hye Kong · 2022 · Endocrines
36. The tumor suppressor role and ceRNA network of miR-1294 in cancer
    Yunan Mao, Jinze Shen, LI FANG, FENG ZHU, Shiwei Duan · 2023 · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
37. Targeting cysteine‑rich angiogenic inducer‑61 by antibody immunotherapy suppresses growth and migration of non‑small cell lung cancer
    Xinpeng Li, Naxin Yuan, Lingdan Lin, Lixia Yin, Yi-Qing Qu · 2018 · Experimental and Therapeutic Medicine
38. Prognosis of gastric adenocarcinoma associated with girdin, Akt, and cortactin
    Yue Zhang, Cheyan Liu, Lei Zhou · 2022 · Annals of Saudi Medicine
39. CD93 serves as a potential biomarker of gastric cancer and correlates with the tumor microenvironment
    Li Zheng, Xiaojie Zhang, Chongyuan Sun, Fei He, Zefeng Li, Dongbing Zhao · 2023 · World Journal of Clinical Cases
40. S100A16 cooperates with DEPDC1 to promote the progression and angiogenesis of nephroblastoma through PI3K/Akt/mTOR pathway
    Geng Geng, Yongtao Xu, Qingfang Li, Qinghao Li, Lili Yuan, Mengyao Dong, Ming Ming · 2023 · Polish Journal of Pathology
41. Recent findings on miR‑370 expression, regulation and functions in cancer (Review)
    Lingling Ye, Jinqiu Wang, Kui Yi, Fen Wang, Jinyan Wang, Hao Wu, Hui Yang, Zhaohui Yang, Quan’an Zhang · 2023 · Oncology Reports
42. Genipin promotes the apoptosis and autophagy of neuroblastoma cells by suppressing the PI3K/AKT/mTOR pathway
    Xinying Liu, Can Zhou, Boli Cheng, Yan Xiong, Qin Zhou, Enyu Wan, Yun He · 2024 · Scientific Reports
43. Selenium promotes broiler myoblast proliferation through the ROS/PTEN/PI3K/AKT signaling axis
    Shengchen Wang, Bing Tian, Xinyu Feng, Yangyang Hu, Liyang Zhang, Ziwei Zhang, Shiwen Xu, Yun Hu, Xiaoyan Cui, Tingting Li et al. · 2024 · Poultry Science
44. Drugging Hijacked Kinase Pathways in Pediatric Oncology: Opportunities and Current Scenario
    Marina Ferreira Cândido, Mariana Medeiros, Luciana Chain Veronez, David Bastos, Karla Laissa Oliveira, Julia Alejandra Pezuk, Elvis Terci Valera, María Sol Brassesco · 2023 · Pharmaceutics
45. Hydrogen sulfide ameliorates abdominal aorta coarctation-induced myocardial fibrosis by inhibiting pyroptosis through regulating eukaryotic translation initiation factor 2α phosphorylation and activating PI3K/AKT1 pathway
    Yaling Li, Zhixiong Wu, Jiangping Hu, Gongli Liu, Hong‐Ming Hu, Fan Ouyang, Jun Yang · 2023 · Korean Journal of Physiology and Pharmacology
46. miRNome expression analysis in canine diffuse large B-cell lymphoma
    Nelly O. Elshafie, Michael Gribskov, Nathanael I. Lichti, Ekramy E. Sayedahmed, Michael O. Childress, Andrea Pires dos Santos · 2023 · Frontiers in Oncology
47. MicroRNAs targeted mTOR as therapeutic agents to improve radiotherapy outcome
    Shahram Taeb, Davoud Rostamzadeh, Seyed Mohammad Amini, Mohammad Rahmati, Mohammad Eftekhari, Arash Safari, Masoud Najafi · 2024 · Cancer Cell International
48. Material Basis and Mechanism of Chansu Injection for COVID-19 Treatment Based on Network Pharmacology and Molecular Docking Technology
    Yong Xu, Wenpan Peng, Di Han, Zhichao Wang, Fanchao Feng, Xianmei Zhou, Qi Wu · 2021 · Evidence-based Complementary and Alternative Medicine
49. CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway
    Yi Zhu, Ling Zuo, Hong Xiong, Shi-Hao Li, Ruiqi Chen, Hongwei Liu · 2023 · Cell Cycle
50. Turning towards nonimmunoreactive tumors: Evaluation of cancer-associated fibroblasts enables prediction of the immune microenvironment and treatment sensitivity in pancreatic cancer
    Siyuan Lu, Jie Hua, Jin Xu, Miaoyan Wei, Liang Chen, Qingcai Meng, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu et al. · 2022 · Computational and Structural Biotechnology Journal
51. The Anthraquinone Derivative C2 Enhances Oxaliplatin-Induced Cell Death and Triggers Autophagy via the PI3K/AKT/mTOR Pathway
    Yuying Li, Wei Yan, Yu Qin, Liwei Zhang, Sheng Xiao · 2024 · International Journal of Molecular Sciences
52. Identification of differential microRNAs and messenger RNAs resulting from ASXL transcriptional regulator 3 knockdown during during heart development
    Zequn Liu, Mi Cheng, Fang Fu, Ru Li, Jin Han, Xin Yang, Qiong Deng, Lu‐Shan Li, Tingying Lei, Dong‐Zhi Li et al. · 2022 · Bioengineered
53. Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways
    Jingni He, Ying Zhang, Baiyu Yao, Lidong Wang, Zhong Tian · 2022 · Molecular and Cellular Endocrinology
54. Osteopontin promotes gastric cancer progression via phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway
    Yue-Chao Qin, Xin Yan, Xiaolin Yuan, Weiwei Yu, Fan-Jie Qu · 2023 · World Journal of Gastrointestinal Oncology
55. Pseudogene ANXA2P2 knockdown shows tumor‐suppressive function by inhibition of the PI3K/PKB pathway in glioblastoma cells
    Hongzao Ni, Rongrong Zhi, Jiandong Zuo, Wenguang Liu, Peng Xie, Zhongwen Zhi · 2021 · Journal of Biochemical and Molecular Toxicology
56. Comparison of Oncogenes, Tumor Suppressors, and MicroRNAs Between Schizophrenia and Glioma: The Balance of Power
    James S. Brown · 2023 · Neuroscience & Biobehavioral Reviews
57. MicroRNA-495 suppresses osteosarcoma invasion and migration by targeting HSP90AA1
    Xin Xiao, Wei Ting Wang, Xiao‐Kang Li, Yuqian Li, Di Yang, Chao Shen, Peng Gao, Jie Wu, Shuo Guo, Zheng Guo · 2018 · Oncotarget
58. The PI3K/Akt Pathway in Herpesvirus Biology: A Double-Edged Sword in Host–Virus Interactions
    Divya Kapoor, Pankaj Sharma, Mannat Singh, Deepak Shukla · 2026 · Microorganisms
59. PIK3CA mutations enhance the adipogenesis of ADSCs in facial infiltrating lipomatosis through TRPV1
    Hongrui Chen, Bin Sun, Wei Gao, Yajing Qiu, Wei Wei, Yongguo Li, Wei Ye, Haoliang Song, Chen Hua, Xiaoxi Lin · 2024 · iScience
60. Autophagy inhibition amplifies anti-tumor immunity effect of dinutuximab beta on neuroblastoma via the VEGFR/AKT/mTOR and ROS/NF-κB pathways
    Fantong Xia, Yongliang Sha, Yan Jin, Jiaxing Yang, Chong Chen, Baocheng Gong, Yun Liu, Qiang Zhao · 2025 · International Immunopharmacology
61. Functional Roles and Mechanistic Insights of YEATS Domain Proteins in Digestive System Tumors
    Fu Chang, Yibo Yang, Xiaocong Li, Huqiang Dong, Kai Liu · 2025 · Digestive Diseases and Sciences
62. Autophagy and Cell Death: Antitumor Drugs Targeting Autophagy
    Hai Zhang, Zhi‐Nan Chen · 2019 · IntechOpen eBooks
63. TMEM60 Promotes the Proliferation and Migration and Inhibits the Apoptosis of Glioma through Modulating AKT Signaling
    Jingwen Wu, Xinghua Tang, Xuejuan Yu, Xiaoli Zhang, Wenjun Yang, Ashima Seth, Qiuan Yang · 2022 · Journal of Oncology · Retracted
64. PTEN is recognized as a prognostic-related biomarker and inhibits proliferation and invasiveness of skull base chordoma cells
    Kaibing Tian, Junpeng Ma, Ke Wang, Da Li, Junting Zhang, Liang Wang, Zhen Wu · 2022 · Frontiers in Surgery
65. Human cytomegalovirus modulates mTORC1 to redirect mRNA translation within quiescently infected monocytes
    Michael J. Miller, Dilruba Akter, Jamil Mahmud, Gary C. T. Chan · 2024 · Journal of Virology
66. Ang-1 promotes tumorigenesis and mediates the anti-cancer effects of Artesunate on Choroidal melanoma via the regulation of Akt/mTOR signaling pathway
    Ningning Yao, Qingyue Ma, Wendan Yi, Yichong Liu, Qian Zhang, Xiaodi Gao, Xintong Zhao, Haowen Wang, Ke Lei, Aihua Sui et al. · 2024 · Cytokine
67. Carbon disulfide induced decidualization disorder in the mice uterus at the window of implantation
    Fengyan Huang, Yanling Wu, Danhua Zhang, Xinai Liu, Zhiping Wang · 2019 · Ecotoxicology and Environmental Safety
68. Ex vivo IL-15 replenishment augments bone marrow precursor cell-mediated adaptive immunity via PI3K-Akt pathway
    Li Xiao Zhang, Rui Ling Chen, Xiao Yan Liao, Xiang You, FENG GUANG GAO · 2020 · Journal of Leukocyte Biology
69. Transcriptome alterations in HepG2 cells induced by shRNA knockdown and overexpression of TMEM2 gene
    Xiuhua Jia, Zhishuo Mo, Qiyi Zhao, Tiancheng Bao, Wenxiong Xu, Zhiliang Gao, Liang Peng, Xiang Zhu · 2020 · Bioscience Biotechnology and Biochemistry
70. Genetic Polymorphisms in microRNA Genes Targeting PI3K/Akt Signal Pathway Modulate Cervical Cancer Susceptibility in a Chinese Population
    Kerong Chen, Zhiling Yan, Xudong Dong, Yan Liang, Yueting Yao, Shao Zhang, Weipeng Liu, Chuanyin Li, Yufeng Yao, Li Shi · 2022 · Frontiers in Genetics
71. Ligustrazine inhibits the viability and motility of colon cancer cells
    Xiaochao Chen, Xiangdong Yang, Jiefei Mu, Chaochi Yue · 2020 · Translational Cancer Research
72. The Prognostic Hub Gene POLE2 Promotes BLCA Cell Growth via the PI3K/AKT Signaling Pathway
    Dongzhen Jiang, Huawei Zhang, Bingde Yin, Minke He, Xuwei Lu, Chang He · 2023 · Combinatorial Chemistry & High Throughput Screening
73. CD52 knockdown inhibits aerobic glycolysis and malignant behavior of NSCLC cells through AKT signaling pathway
    Yini Cai, Jiali Zhao, Chen Huan Luo, Ming Fang, Yanling Yi, Yu Chen, Peng Huang, Lingmin Liao, Long Huang · 2024 · Journal of Cancer
74. The Exploratory Study of the PTEN-AKT/mTOR Signaling Pathway in the Corresponding Dorsal Root Ganglion during Compensatory Repair via Small Gap Amplification in Sciatic Nerve Injury
    Fei Yu, Tiantian Qi, Yusong Yuan, Jian Weng, Tianbing Wang, Yuhui Kou, Hui Zeng · 2024 · Journal of Integrative Neuroscience
75. JAML overexpressed in colorectal cancer promotes tumour proliferation by activating the PI3K-AKT-mTOR signalling pathway
    Yuying Fang, Yanan Liu, Zhilin Dong, Xinchao Zhao, Mingyan Zhang, Yawen Zheng, Chunsheng Yang, Yufeng Wang, Ning Liu, Peng Yan et al. · 2024 · Scientific Reports
76. Hsa_circ_0074491 regulates the malignance of cholesteatoma keratinocytes by modulating the PI3K/Akt pathway by binding to miR-22-3p and miR-125a-5p
    Yunlong Hu, Xudong Qian · 2021 · Medicine
77. Kaposi's sarcoma-associated herpes virus-derived microRNA K12–1 over-activates the PI3K/Akt pathway to facilitate cancer progression in HIV-related gastrointestinal Kaposi's sarcoma
    Xiaoling Huang, Wei Rao, Chun Wang, Jiajie Lu, Ziqiong Li, Wenjie Kong, Yan Feng, Tian Xu, Rziya Apaer, Feng Gao · 2022 · SLAS DISCOVERY
78. Over-expression of EPB41L3 promotes apoptosis of human cervical carcinoma cells through PI3K/AKT signaling
    Gulixian Tuerxun, Tangnuer Abulimiti, Guligeina Abudurexiti, Guzhanuer Abuduxikuer, Yuanyuan Zhang, Guzhalinuer Abulizi · 2022 · Acta Biochimica Polonica
79. E2F1-activated NRSN2 promotes esophageal squamous cell carcinoma progression through AKT/mTOR pathway
    Zhaoyang Yan, Tongxin Xu, Juntao Lu, Zheng Wu, Xiaoxu Li, Jinsheng Xu, Wei Guo, Zhiming Dong · 2022 · Pathology - Research and Practice
80. IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway
    Juan Gao, Shiqi Suo, Jingxia Li, Chunxia Wang, Ranran Deng, Yuxia Hu, Chunzheng Zhang · 2023 · Experimental and Therapeutic Medicine
81. miR-19a mediates the mechanism by which SPHK2 regulates hypopharyngeal squamous cell carcinoma progression through the PI3K/AKT axis.
    Ji Song, Yanshi Li, Tao Lu, Min Pan, Zhihai Wang, Chuan Liu, Yang Liao, Guohua Hu · 2023 · PubMed Central
82. The emerging role and clinical significance of circRNAs in papillary thyroid cancer
    Jing Ma, Jing Xu, Xiaoqi Zhang, Jinxing Quan · 2024 · Frontiers in Endocrinology
83. Ipriflavone Suppresses Growth of Esophageal Squamous Cell Carcinoma Through Inhibiting mTOR In Vitro and In Vivo
    Xiaodan Shi, Yuanyuan Zhang, Xiaomeng Xie, Mengjun Pang, Kyle Vaughn Laster, Jian Li, Xinli Ma, Kangdong Liu, Zigang Dong, Dong Joon Kim · 2021 · Frontiers in Oncology
84. Kinase Inhibition in Relapsed/Refractory Leukemia and Lymphoma Settings: Recent Prospects into Clinical Investigations
    Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Emerson Lucena da Silva, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Manoel Odorico de Moraes, Maria Elisabete Amaral de Moraes, Raquel Carvalho Montenegro, Rommel Mário Rodríguez Burbano, André Salim Khayat et al. · 2021 · Pharmaceutics
85. Hypoxia Promotes Glioma Stem Cell Proliferation by Enhancing the 14-3-3β Expression via the PI3K Pathway
    Weidong Cao, Qiang Zhou, Hongwei Wang, Wei Rao, Gang Cheng, Peng Wang, Sheng-Li Guo, Bin Ren, Jianning Zhang · 2022 · Journal of Immunology Research
86. Discovery of P11–2: A Potent First-in-Class MNK1-Targeting PROTAC Degrader for the Treatment of Cancer
    Zhongcheng Yang, Yuxia Liu, Zibin Liao, Lianru Chen, Zhiling Liang, Luyong Zhang, Zheng Li · 2025 · Journal of Medicinal Chemistry
87. Mechanical Cell Reprogramming on Tissue-Mimicking Hydrogels for Cancer Cell Transdifferentiation
    Xueqing Ren, Yachao Wang, Mengcheng Lei, Yi Zou, Pengjie Li, Fukang Qi, Jinyun Shi, Han Xie, Ming‐Yu Zhang, Wenhui Wang et al. · 2025 · Research
88. Integrated analysis of mRNA and miRNA expression profiles reveals muscle growth differences between fast- and slow-growing king ratsnakes (Elaphe carinata)
    Shaukat Ali Khan, Jun He, Shuaitao Deng, Huijuan Zhang, Guangxuan Liu, Shikun Li, Dong Tang, Jihui Zhang, Yilin Shu, Hailong Wu · 2020 · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology
89. PHF5A promotes esophageal squamous cell carcinoma progression via stabilizing VEGFA
    Zhiwei Chang, Yongxu Jia, Ming Gao, Lijie Song, Weijie Zhang, Ruihua Zhao, Dandan Yu, Xiaolei Liu, Jing Li, Yanru Qin · 2024 · Biology Direct
90. The ratio of PKM1/PKM2 is the key factor affecting the glucose metabolism and biological function of colorectal cancer cells
    Liang Ma, Xue Zhang, Yan Liu, Hui Jin, Dan Xiao Li, Hui Zhang, Li Feng, Jing Zuo, Yudong Wang, Jiayin Liu et al. · 2024 · Translational Cancer Research
91. Auranofin Suppresses the Growth of Canine Mammary Tumour Cells and Induces Apoptosis via the PI3K / AKT Pathway
    Zhaoyan Lin, Rong Chen, Jiao Wang, Yu Zheng, Zixuan He, Ye Yan, Linxi Zhang, Xiaohong Huang, Hong Zhang · 2024 · Veterinary and Comparative Oncology
92. Bergenin exerts anti-cancer activity in hepatocellular carcinoma via the PI3K/Akt/mTOR and MAPK/ERK pathways
    Guo‐Dong Lu, Xun Zhuang, Chunrong Wang, Zhenghui Ge, Mengjie Wu, Mengjiao Chen, Zhen Chen, Jianghong Hu, Haoqing Zhai · 2025 · Journal of Molecular Histology
93. RETRACTED ARTICLE: K-Ras G12V/Y40C -PI3K/AKT pathway regulates H1.4 S35ph through PKA to promote the occurrence and development of osteosarcoma cancer
    Jingzhe Zhang, Wanguo Liu, Hang Dong, Wenjun Wang · 2019 · Artificial Cells Nanomedicine and Biotechnology · Retracted
94. ADAMTS8 Expression is a Potential Prognostic Biomarker for Postoperative Metastasis in Lymph Node-Negative Early-Stage Invasive Breast Carcinoma Patients
    Yao Li, Xin Yang, Jie Sun, Yangyang Zhao, Qi Zhou, Bin Hua · 2021 · Pharmacogenomics and Personalized Medicine
95. Niuhuang (Bovis Calculus)-Shexiang (Moschus) combination induces apoptosis and inhibits proliferation in hepatocellular carcinoma via PI3K/AKT/mTOR pathway
    Di-Min Ning, Zhe Deng, Wu Yongrong, Si Mei, Teng Yongjie, Qing Zhou, Tian Xuefei · 2022 · Digital Chinese Medicine
96. Community detection in empirical kinase networks identifies new potential members of signalling pathways
    Celia De Los Angeles Colomina Basanta, Marya Bazzi, Maruan Hijazi, Conrad Bessant, Pedro R. Cutillas · 2023 · PLoS Computational Biology
97. Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway
    Ming Li, Zhao Huang, Yuxiang Zhou · 2023 · Advances in Clinical and Experimental Medicine
98. Plant homeodomain-finger protein 5A: A key player in cancer progression
    Patrick Diaba‐Nuhoho · 2023 · Biomedicine & Pharmacotherapy
99. LncRNA EGFR-AS1 Regulates Breast Cancer Cells Function and Sensitivity to Docetaxel Via the miR-149-5p/ELP5 Axis
    Shiping Li, Xiaoyi Mi, Mingfang Sun, Jie Zhang, Miaomiao Hao, Qixue Cao, Kexin Diao, Jian Wang, Hanwen Li, Bin Liu · 2021 · Research Square
100. GLS1 promotes lipid metabolism in hepatocellular carcinoma by regulating the PI3K/AKT/mTORC1 signaling pathway through SREBP-1
     Yaocheng Sun · 2025 · American Journal of Translational Research