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Linkage, recombination and mapping
Abstract
So far we have seen that some traits of the laboratory mouse exhibit segregation in conformity with Mendel’s principle of segregation of alleles and that some sets of two traits exhibit assortment in conformity with Mendel’s principle of random assortment of non-alleles. In this chapter, we shall deal with an experiment in which the first principle holds but the second does not. Instead of random or independent assortment of non-alleles, we shall be led to infer, as many others have done since 1910, when Morgan perceived the phenomenon, that there can be non-random or dependent assortment of non-alleles. This phenomenon is called genetic linkage or, simply, linkage.
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Citations
Cited by
Weinberg, J. B., Granger, D. L., Pisetsky, D. S., Seldin, M. F., Misukonis, M. A., Mason, S. N., Pippen, A. M., Ruiz, P., Wood, E. R., & Gilkeson, G. S. (1994) · The Journal of experimental medicine · doi:10.1084/jem.179.2.651 · Cited by 435
The mouse fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster
Lynch, D. H., Watson, M. L., Alderson, M. R., Baum, P. R., Miller, R. E., Tough, T., Gibson, M., Davis-Smith, T., Smiths, C. A., Hunter, K., et al. (1994) · Immunity · doi:10.1016/1074-7613(94)90106-6 · Cited by 331
Watson, M. L., Kingsmore, S. F., Johnston, G. I., Siegelman, M. H., Le Beau, M. M., Lemons, R. S., Bora, N. S., Howard, T. A., Weissman, I. L., & McEver, R. P. (1990) · The Journal of experimental medicine · doi:10.1084/jem.172.1.263 · Cited by 157
Cunningham, N. S., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Reddi, A. H., & Lee, S.-J. (1995) · Growth Factors · doi:10.3109/08977199509028956 · Cited by 104
EHD1—An EH-Domain-Containing Protein with a Specific Expression Pattern
Mintz, L., Galperin, E., Pasmanik-Chor, M., Tulzinsky, S., Bromberg, Y., Kozak, C. A., Joyner, A., Fein, A., & Horowitz, M. (1999) · Genomics · doi:10.1006/geno.1999.5800 · Cited by 80
Metadata
- Authors
- Green, E. L.
- Venue
- Genetics and Probability in Animal Breeding Experiments
- Publisher
- Macmillan Education UK
- Published
- 1981
- Pages
- 77-113
- OpenAlex
- W2468883625
- Cited by
- 271
- References
- 0
- FWCI
- 0.00
- Type
- book chapter
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Linkage, recombination and mapping. https://app.cochat.ai/papers/10.1007/978-1-349-04904-2_4
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- Green, E. L. (1981). Linkage, recombination and mapping. Genetics and Probability in Animal Breeding Experiments. https://doi.org/10.1007/978-1-349-04904-2_4
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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