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Cited by 142Substance Abuse Treatment and OutcomesChild Welfare and AdoptionGenetic Associations and Epidemiology

Psychopathology in adopted-out children of alcoholics. The Stockholm Adoption Study

Cloninger, C. Robert, Bohman, Michael, Sigvardsson, Sören, von Knorring, Anne-Liis·1985·Recent Developments in Alcoholism
DOI 10.1007/978-1-4615-7715-7_4
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Abstract

The inheritance of alcohol abuse and other psychopathology was studied in 862 men and 913 women adopted by nonrelatives at an early age in Sweden. Both male and female adoptees had a greater risk of alcohol abuse if their biologic, but not adoptive, parents were alcoholic. We distinguished two types of alcoholism that have distinct genetic and environmental causes and that differ in frequency of alcohol abuse and somatoform disorders in women. The combination of both genetic and environmental risk factors is required for development of alcoholism in the most common type. In contrast, in families with the less common type of susceptibility, alcohol abuse is highly heritable in the men, but the women have multiple somatic complaints without alcohol abuse. The implications of these findings of genetic heterogeneity and gene-environment interaction are discussed in relation to research, prevention, and treatment.

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Crossref · 10.1007/978-1-4615-7715-7_4

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  • Adopted children may be at greater risk for aggression than nonadoptees because birth parents who give up children may have increased rates of disordered behaviors including substance use, criminal offending, and aggression.

    “Adopted children may also be at greater risk for aggression compared to nonadoptees, since birth parents giving up their children may have increased rates of disordered behaviors, including substance use, criminal offending, and aggression (Cloninger et al., 1985; Lewis et al., 2001).”

    From Human Aggression Across the Lifespan (2011) · cites this paper as Cloninger et al., 1985

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Authors
Cloninger, C. R., Bohman, M., Sigvardsson, S., & von Knorring, A.-L.
Affiliations
  • Washington University in St. Louis (US)
  • Umeå University (SE)
ORCID
Cloninger, C. Robert
Venue
Recent Developments in Alcoholism
Publisher
Springer US
Published
1985
Volume
3
Pages
37-51
DOI
10.1007/978-1-4615-7715-7_4
OpenAlex
W1550048104
Cited by
142
References
29
Citations by year
2024: 1 · 2019: 1 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 1 · 2013: 2 · 2012: 2
FWCI
11.73
Type
book chapter
Language
en
Open access
closed
Locations
  • Springer eBooks (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Safety Research › Child Welfare and Adoption
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords
alcoholism, heritability, genetic susceptibility, gene-environment interaction, adopted children, biological parents, somatoform disorders, psychopathology, genetic heterogeneity, alcohol abuse risk
MeSH terms
Adoption, Alcoholism, Child Care, Crime, Female, Humans, Male, Risk, Social Class, Social Environment, Mood Disorders

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