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Cre Driver Mice Targeting Macrophages

Shi, Jiayuan, Hua, Li, Harmer, Danielle, Li, Peishan, Ren, Guangwen·2018·Methods in Molecular Biology
DOI 10.1007/978-1-4939-7837-3_24PMC PMC6331202
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  • The efficiency of loxP-mediated gene recombination driven by LysM-Cre varies markedly among myeloid cell types, with the highest efficiency in mature macrophages (approximately 83-98%) and much lower efficiency in splenic DCs (about 16%).

    “It is important to note that the efficiency of loxP-mediated gene recombination driven by LysM-Cre varies markedly among myeloid cell types63–65. with the highest efficiency observed in mature macrophages (approximately 83–98%) and much lower efficiency in splenic DCs (about 16%)44.”

    From Macrophage INSIG1 deficiency drives psoriasiform dermatitis via the SREBP2-STAT1 axis (2026) · cites this paper as [63]

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Research works printed but not linked: 59

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Metadata

Authors
Shi, J., Hua, L., Harmer, D., Li, P., & Ren, G.
Venue
Methods in Molecular Biology
Publisher
Springer New York
Published
2018
Pages
263-275
ISSN
  • 1064-3745
  • 1940-6029
DOI
10.1007/978-1-4939-7837-3_24
PMC
PMC6331202
Cited by
145
References
11
Licence
www.springer.com/tdm (unspecified)

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