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Zeta Potential Measurement
Abstract
This chapter describes a method for the measurement of the electrostatic potential at the electrical double layer surrounding a nanoparticle in solution. This is referred to as the zeta potential. Nanoparticles with a zeta potential between -10 and +10 mV are considered approximately neutral, while nanoparticles with zeta potentials of greater than +30 mV or less than -30 mV are considered strongly cationic and strongly anionic, respectively. Since most cellular membranes are negatively charged, zeta potential can affect a nanoparticle's tendency to permeate membranes, with cationic particles generally displaying more toxicity associated with cell wall disruption. This technique is demonstrated for two types of nanoparticles commonly used in biological applications: colloidal gold (strongly anionic) and amine-terminated PAMAM dendrimer (strongly cationic).
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Cited by
Németh, Z., Csóka, I., Semnani Jazani, R., Sipos, B., Haspel, H., Kozma, G., Kónya, Z., & Dobó, D. G. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14091798 · Cited by 452
Alginate-based nanomaterials: Fabrication techniques, properties, and applications
Fernando, I. P. S., Lee, W., Han, E. J., & Ahn, G. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2019.123823 · Cited by 391
Effect of silver nanoparticles on Candida albicans biofilms: an ultrastructural study
Lara, H. H., Romero-Urbina, D. G., Pierce, C., Lopez-Ribot, J. L., Arellano-Jiménez, M. J., & Jose-Yacaman, M. (2015) · Journal of Nanobiotechnology · doi:10.1186/s12951-015-0147-8 · Cited by 323
Yahaya Pudza, M., Zainal Abidin, Z., Abdul Rashid, S., Md Yasin, F., Noor, A. S. M., & Issa, M. A. (2020) · Nanomaterials · doi:10.3390/nano10020315 · Cited by 218
Lara, H. H., Ixtepan-Turrent, L., Jose Yacaman, M., & Lopez-Ribot, J. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b20708 · Cited by 116
Metadata
- Authors
- Clogston, J. D., & Patri, A. K.
- Venue
- Methods in Molecular Biology
- Publisher
- Humana Press
- Published
- 2010-10-19
- Volume
- 697
- Pages
- 63-70
- ISSN
- 1064-3745 (ISSN-L)
- 1940-6029
- OpenAlex
- W2412497043
- Cited by
- 1,324
- References
- 0
- FWCI
- 33.69
- Type
- book chapter
- Language
- en
- Open access
- closed
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