The DOI matches its Crossref record, with a small difference in title or year; 62 of the 63 references it cites were found in a registry or an index.
The role of bone marrow derived mesenchymal stem cells in sports injuries
Abstract
The therapeutic use of bone marrow-derived mesenchymal stem cells (BM-MSCs) has been applied to many different tissue types that are vulnerable to sports injuries. Avenues of treatment include direct injection of BM-MSCs into the defect, however although minimally invasive, research has highlighted flaws which have been improved upon with the use of scaffolds. BM-MSCs have been applied via many different scaffold types, for example PLGA, collagen gel and coral each with advantages and disadvantages of which can be improved through further research. As a cell source for tissue engineering, BM-MSCs are ideal due to the minimal invasion of aspiration, high in vitro proliferation rate and the ability to maintain their differentiating capacity. The vast majority of these studies are at the small animal stage and therefore further work using larger animal models, and ideally humans is required.
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“Their multiple differentiation potential for therapeutic application when implanted with biodegradable scaffolds has been demonstrated in several previous studies [16–19].”
Citations
Cites
Multilineage potential of adult human mesenchymal stem cells
Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052
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Stem cell therapy in a caprine model of osteoarthritis
Murphy, M. J., Fink, D. J., Hunziker, E. B., & Barry, F. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11365 · Cited by 1,103
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Material Properties and Structure-Function Relationships in the Menisci
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Bone regeneration by implantation of purified, culture‐expanded human mesenchymal stem cells
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Research works printed but not linked: 1
- Kavalkovich, K., Murphy, J., & Barry, F. 2000, "Adhesion of mesenchymal stem cells to fibrillated osteoarthritic cartilage.", Osteoarthritis and Cartilage, vol. 8.
Cited by
Sorted by citations
Tendon and ligament regeneration and repair: Clinical relevance and developmental paradigm
Yang, G., Rothrauff, B. B., & Tuan, R. S. (2013) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.21041 · Cited by 484
Chu, D., Nguyen, T. T. P., Tien, N. L. B., Khoa, T. D., Thanh, V. V., Quang, T. L., Truong, D. T., Pham, V.-H., Ngọc, V. T. N., Chu-Dinh, T., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030708 · Cited by 246
Khan, W. S., Rayan, F., Dhinsa, B. S., & Marsh, D. (2011) · Stem Cells International · doi:10.1155/2012/236231 · Cited by 106
Self-citationAntimicrobial activity of mesenchymal stem cells against Staphylococcus aureus
Yagi, H., Chen, A. F., Hirsch, D. C., Rothenberg, A. C., Tan, J., Alexander, P. G., & Tuan, R. S. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-01807-3 · Cited by 82
Teng, C., Zhou, C., Xu, D., & Bi, F. (2016) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-016-0433-7 · Cited by 64
Metadata
- Authors
- Vris, A., Aresti, N., Khan, W. S., & Malik, A. A.
- Affiliations
- Barts Health NHS Trust (GB)
- University of Cambridge (GB)
- Stoke Mandeville Hospital (GB)
- Corresponding author
- Malik, Atif A.
- Venue
- Stem Cells in Clinical Applications
- Publisher
- Springer International Publishing
- Published
- 2016
- Volume
- 5
- Issue
- 4
- Pages
- 277-291
- ISSN
- 2365-4198 (ISSN-L)
- 2365-4201
- OpenAlex
- W136516790
- Cited by
- 28
- References
- 63
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2018: 1 · 2017: 4 · 2016: 6
- FWCI
- 8.75
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Stem cells in clinical applications (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Mesenchymal stem cell research
- Health Sciences › Dentistry › Periodontics › Periodontal Regeneration and Treatments
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Keywords
- bone marrow-derived mesenchymal stem cells, sports injuries, cell therapy, scaffolds, PLGA, collagen gel, coral scaffold, tissue engineering, cell injection, tissue regeneration
- MeSH terms
- Animals, Athletic Injuries, Bone and Bones, Bone Marrow Cells, Cartilage, Humans, Ligaments, Muscles, Tendons, Tissue Engineering, Mesenchymal Stem Cell Transplantation, Mesenchymal Stem Cells
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