General Principles of Pharmacokinetics

Preskorn, S. H.; Catterson, M. L.

doi:10.1007/978-3-642-18500-7_2

Cited by 14Pharmacogenetics and Drug MetabolismTreatment of Major DepressionAntibiotics Pharmacokinetics and Efficacy

General Principles of Pharmacokinetics

Preskorn, S. H., Catterson, M. L.·2004·Handbook of Experimental Pharmacology

DOI 10.1007/978-3-642-18500-7_2

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Several factors can influence the rate and extent of absorption of oral antipsychotics, including drug dissolution, drug solubility, susceptibility to enzymatic reactions, gastric pH, drug-drug interactions, and food-drug interactions.
“Several factors can influence the rate and extent of absorption of oral antipsychotics, including drug dissolution, drug solubility, susceptibility to enzymatic reactions, gastric pH, drug–drug interactions, and food–drug interactions [22–24].”
From Pharmacokinetic Characteristics of Long-Acting Injectable Antipsychotics for Schizophrenia: An Overview (2021) · cites this paper as [22]

The Pharmacological Basis of Therapeutics
(1976) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/33.4.373a · Cited by 9,216 · see citing works
Drug Metabolism and Disposition
(2014) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12259_4 · Cited by 2,518 · see citing works
The Pharmacological Basis of Therapeutics
Leopold, I. H. (1971) · American Journal of Ophthalmology · doi:10.1016/0002-9394(71)91343-2 · Cited by 1,673 · see citing works
Understanding the Dose-Effect Relationship
Holford, N. H. G., & Sheiner, L. B. (1981) · Clinical Pharmacokinetics · doi:10.2165/00003088-198106060-00002 · Cited by 1,147 · see citing works
Mechanism of the Cardiotoxic Actions of Terfenadine
Woosley, R. L. (1993) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1993.03500120070028 · Cited by 646 · see citing works
Textbook of psychopharmacology
Edwards, G. (1975) · Nature · doi:10.1038/258648b0 · Cited by 583 · see citing works
Biochemistry and molecular biology of the human CYP2C subfamily
Goldstein, J. A., & de Morais, S. M. F. (1994) · Pharmacogenetics · doi:10.1097/00008571-199412000-00001 · Cited by 535 · see citing works
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.
Evans, D. A. P., Mahgoub, A., Sloan, T. P., Idle, J. R., & Smith, R. L. (1980) · Journal of Medical Genetics · doi:10.1136/jmg.17.2.102 · Cited by 533 · see citing works
Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)
Hyttel, J. (1994) · International Clinical Psychopharmacology · doi:10.1097/00004850-199403001-00004 · Cited by 492 · see citing works
Anatomy of body water and electrolytes
Edelman, I. S., & Leibman, J. (1959) · The American Journal of Medicine · doi:10.1016/0002-9343(59)90346-8 · Cited by 474 · see citing works
The effect of selective serotonin re‐uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes.
Crewe, H. K., Lennard, M., Tucker, G., Woods, F. R., & Haddock, R. E. (1992) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1992.tb04134.x · Cited by 468 · see citing works
CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
Hesse, L. M., Venkatakrishnan, K., Court, M. H., Moltke, L. L., Duan, S., Shader, R. I., & Greenblatt, D. J. (2000) · Drug Metabolism and Disposition · doi:10.1016/s0026-895x(24)12046-9 · Cited by 397 · see citing works
Fluvoxamine is a potent inhibitor of cytochrome P4501A2
Brøsen, K., Skjelbo, E., Rasmussen, B. B., Poulsen, H. E., & Loft, S. H. (1993) · Biochemical Pharmacology · doi:10.1016/0006-2952(93)90272-x · Cited by 374 · see citing works
Clinically Relevant Pharmacology of Selective Serotonin Reuptake Inhibitors: An Overview with Emphasis on Pharmacokinetics and Effects on Oxidative Drug Metabolism
Preskorn, S. H. (1997) · Clinical Pharmacokinetics · doi:10.2165/00003088-199700321-00003 · Cited by 370 · see citing works
Self-citation
The genetic polymorphism of debrisoquine/sparteine metabolism — Clinical aspects
Eichelbaum, M. F., & Gross, A. S. (1990) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(90)90025-w · Cited by 368 · see citing works
Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man
K�pfer, A., & Preisig, R. (1984) · European Journal of Clinical Pharmacology · doi:10.1007/bf00541938 · Cited by 363 · see citing works
Binding of antidepressants to human brain receptors: focus on newer generation compounds
Cusack, B. M., Nelson, A. N., & Richelson, E. (1994) · Psychopharmacology · doi:10.1007/bf02244985 · Cited by 349 · see citing works
Binding of Drugs by Albumin Plasma Protein
Vallner, J. J. (1977) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600660402 · Cited by 335 · see citing works
Clinically Significant Pharmacokinetic Drug Interactions with Carbamazepine
Spina, E., Pisani, F., & Perucca, E. (1996) · Clinical Pharmacokinetics · doi:10.2165/00003088-199631030-00004 · Cited by 331 · see citing works
Paroxetine
Dechant, K. L., & Clissold, S. P. (1991) · Drugs · doi:10.2165/00003495-199141020-00007 · Cited by 325 · see citing works
Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine
Jeppesen, U., Gram, L. F., Vistisen, K. K., Loft, S. H., Poulsen, H. E., & Brøsen, K. (1996) · European Journal of Clinical Pharmacology · doi:10.1007/s002280050163 · Cited by 321 · see citing works
Clinical Pharmacokinetics of Mirtazapine
Timmer, C. J., Sitsen, J. M. A., & Delbressine, L. P. C. (2000) · Clinical Pharmacokinetics · doi:10.2165/00003088-200038060-00001 · Cited by 319 · see citing works
A review of the metabolism and pharmacokinetics of paroxetine in man
Kaye, C. M., Haddock, R. E., Langley, P. F., MELLOWS, G., Tasker, T. C. G., Zussman, B. D., & Greb, W. H. (1989) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1989.tb07176.x · Cited by 268 · see citing works
Pharmacokinetics of antidepressants: why and how they are relevant to treatment.
Cummings, J. L. (1993) · PubMed · Cited by 263 · see citing works
Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds
Hammer, W., & Sjöqvist, F. (1967) · Life Sciences · doi:10.1016/0024-3205(67)90218-4 · Cited by 263 · see citing works
Inhibition by fluoxetine of cytochrome P450 2D6 activity
Otton, S. V., Wu, D., Joffe, R. T., Cheung, S. W., & Sellers, E. M. (1993) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1993.43 · Cited by 258 · see citing works
Seizures and bupropion: a review.
Davidson, J. R. T. (1989) · PubMed · Cited by 237 · see citing works
Neuroendocrine evidence for serotonin receptor hypersensitivity in panic disorder
Kahn, R. S., Asnis, G. M., Wetzler, S. E., & van Praag, H. M. (1988) · Psychopharmacology · doi:10.1007/bf00216062 · Cited by 221 · see citing works
Safety of mirtazapine: a review
Montgomery, S. A. (1995) · International Clinical Psychopharmacology · doi:10.1097/00004850-199512004-00006 · Cited by 215 · see citing works
Pharmacokinetics of Citalopram in Relation to the Sparteine and the Mephenytoin Oxidation Polymorphisms
Sindrup, S. H., Brøsen, K., Hansen, M. G. J., Aaes‐Jørgensen, T., Overø, K. F., & Gram, L. F. (1993) · Therapeutic Drug Monitoring · doi:10.1097/00007691-199302000-00002 · Cited by 213 · see citing works
Metabolic Drug Interactions
Levy, R. H., Thummel, K. E., Trager, W. F., Hansten, P. D., & Eichelbaum, M. F. (2000) · Cited by 208 · see citing works
Introduction of a Composite Parameter to the Pharmacokinetics of Venlafaxine and its Active O‐Desmethyl Metabolite
Klamerus, K. J., Moloney, K., Rudolph, R. L., Sisenwine, S. F., Jusko, W. J., & Chiang, S. T. (1992) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1992.tb03875.x · Cited by 203 · see citing works
Effect of phenytoin on plasma clozapine concentrations in two patients.
Preskorn, S. H., & Fast, G. A. (1991) · PubMed · Cited by 201 · see citing works
Self-citation
Fluoxetine: clinical pharmacology and physiologic disposition.
Lemberger, L., Bergstrom, R. F., Wolen, R. L., Farid, N. A., Enas, G. G., & Aronoff, G. R. (1985) · PubMed · Cited by 196 · see citing works
Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine
Br�sen, K., Hansen, J. G., Nielsen, K. K., Sindrup, S. H., & Gram, L. F. (1993) · European Journal of Clinical Pharmacology · doi:10.1007/bf00316471 · Cited by 193 · see citing works
Principles and practice of psychopharmacotherapy
Janicak, P. G. (2001) · Cited by 190 · see citing works
Pharmacokinetics of Desipramine Coadministered With Sertraline or Fluoxetine
Preskorn, S., Alderman, J. A., Chung, M., Harrison, W. M., Messig, M., & Harris, S. I. (1994) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199404000-00002 · Cited by 189 · see citing works
Self-citation
The plasma protein binding of basic drugs.
Routledge, P. (1986) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1986.tb02927.x · Cited by 181 · see citing works
Textbook of Psychopharmacology
(1995) · Nature Medicine · doi:10.1038/nm0895-834 · Cited by 178 · see citing works
Inhibition of Alprazolam and Desipramine Hydroxylation In Vitro by Paroxetine and Fluvoxamine
Moltke, L. L., Greenblatt, D. J., Court, M. H., Duan, S. X., Harmatz, J. S., & Shader, R. I. (1995) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199504000-00008 · Cited by 175 · see citing works
Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction
Bergstrom, R. F., Peyton, A. L., & Lemberger, L. (1992) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1992.18 · Cited by 169 · see citing works
Pharmacokinetic and electroencephalographic study of intravenous diazepam, midazolam, and placebo
Greenblatt, D. J., Ehrenberg, B. L., Gunderman, J., Locniskar, A., Scavone, J. M., Harmatz, J. S., & Shader, R. I. (1989) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1989.41 · Cited by 168 · see citing works
Inhibitors of imipramine metabolism by human liver microsomes.
Skjelbo, E., & Brøsen, K. (1992) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1992.tb04133.x · Cited by 163 · see citing works
Pharmacokinetics and Safety of Duloxetine, a Dual‐Serotonin and Norepinephrine Reuptake Inhibitor
Sharma, A., Goldberg, M. J., & Cerimele, B. J. (2000) · The Journal of Clinical Pharmacology · doi:10.1177/00912700022008810 · Cited by 147 · see citing works
CYP2D6 Inhibition by Fluoxetine, Paroxetine, Sertraline, and Venlafaxine in a Crossover Study: Intraindividual Variability and Plasma Concentration Correlations
Alfaro, C. L., Lam, Y. W. F., Simpson, J., & Ereshefsky, L. (2000) · The Journal of Clinical Pharmacology · doi:10.1177/009127000004000108 · Cited by 142 · see citing works
Polymorphic debrisoquin hydroxylation in 757 Swedish subjects
Steiner, E., Bertilsson, L., Säwe, J., Bertling, I., & Sjöqvist, F. (1988) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1988.176 · Cited by 133 · see citing works
Effect of Fluvoxamine on the Pharmacokinetics of Imipramine and Desipramine in Healthy Subjects
Spina, E., Pollicino, A., Avenoso, A., Campo, G. M., Perucca, E., & Caputi, A. P. (1993) · Therapeutic Drug Monitoring · doi:10.1097/00007691-199306000-00011 · Cited by 132 · see citing works
Trazodone kinetics: Effect of age, gender, and obesity
Greenblatt, D. J., Friedman, H. L., Burstein, E. S., Scavone, J. M., Blyden, G. T., Ochs, H. R., Miller, L. G., Harmatz, J. S., & Shader, R. I. (1987) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1987.132 · Cited by 127 · see citing works
Metabolism of the Antidepressant Mirtazapine in Vitro: Contribution of Cytochromes P-450 1A2, 2D6, and 3A4
Stürmer, E., Moltke, L. L., Shader, R. I., & Greenblatt, D. J. (2000) · Drug Metabolism and Disposition · doi:10.1016/s0026-895x(24)12045-7 · Cited by 126 · see citing works
The Effect of Age On Serum Albumin in Healthy Males: Report From The Normative Aging Study
Campion, E. W., Delabry, L. O., & Glynn, R. J. (1988) · Journal of Gerontology · doi:10.1093/geronj/43.1.m18 · Cited by 125 · see citing works
Central Nervous System Toxicity of Tricyclic Antidepressants: Phenomenology, Course, Risk Factors, and Role of Therapeutic Drug Monitoring
Preskorn, S., & Jerkovich, G. S. (1990) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199004000-00003 · Cited by 124 · see citing works
Self-citation
Analysis of Enantiomers of Citalopram and Its Demethylated Metabolites in Plasma of Depressive Patients Using Chiral Reverse-Phase Liquid Chromatography
Rochat, B., Amey, M., & Baumann, P. (1995) · Therapeutic Drug Monitoring · doi:10.1097/00007691-199506000-00011 · Cited by 123 · see citing works
Nefazodone and Imipramine in Major Depression: A Placebo-Controlled Trial
Rickels, K., Schweizer, E. E., Clary, C. M., Fox, I., & Weise, C. C. (1994) · The British Journal of Psychiatry · doi:10.1192/bjp.164.6.802 · Cited by 123 · see citing works
Bupropion in Depression
Golden, R. N. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800260055007 · Cited by 122 · see citing works
Metabolism and kinetics of bupropion.
Dh, S. (1983) · PubMed · Cited by 121 · see citing works
Desipramine Pharmacokinetics When Coadministered With Paroxetine or Sertraline in Extensive Metabolizers
Alderman, J. A., Preskorn, S., Greenblatt, D. J., Harrison, W. M., Penenberg, D. N., Allison, J., & Chung, M. (1997) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199708000-00008 · Cited by 121 · see citing works
Self-citation
Tricyclic antidepressant-induced seizures and plasma drug concentration.
Preskorn, S., & Fast, G. A. (1992) · PubMed · Cited by 119 · see citing works
Self-citation
Placebo-Controlled Trial of Venlafaxine for the Treatment of Major Depression
Schweizer, E. E., Weise, C., Clary, C. M., Fox, I., & Rickels, K. (1991) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199108000-00002 · Cited by 119 · see citing works
Clinical implications of the pharmacology of sertraline
WARRINGTON, S. J. (1991) · International Clinical Psychopharmacology · doi:10.1097/00004850-199112002-00004 · Cited by 119 · see citing works
A double-blind comparison of nefazodone, imipramine, and placebo in major depression.
Fontaine, R., Ontiveros, A., Elie, R., Kensler, T. T., Roberts, D. L., Kaplita, S., Ecker, J., & Faludi, G. (1994) · PubMed · Cited by 117 · see citing works
Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: potential drug interactions with bupropion.
Hesse, L. M., Moltke, L. L., Shader, R. I., & Greenblatt, D. J. (2001) · PubMed · Cited by 117 · see citing works
Xenobiotic and endobiotic inhibitors of cytochrome p-450dbl function, the target of the debrisoouine/sparteine type polymorphism
Fonné‐Pfister, R., & Meyer, U. (1988) · Biochemical Pharmacology · doi:10.1016/0006-2952(88)90063-9 · Cited by 116 · see citing works
Cytochrome P450 Enzymes
Harvey, A. T., & Preskorn, S. (1996) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199608000-00002 · Cited by 113 · see citing works
Self-citation
Fluoxetine kinetics and protein binding in normal and impaired renal function
Aronoff, G. R., Bergstrom, R. F., Pottratz, S. T., Sloan, R. S., Wolen, R. L., & Lemberger, L. (1984) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1984.152 · Cited by 113 · see citing works
Brain concentrations of tricyclic antidepressants: Single-dose kinetics and relationship to plasma concentrations in chronically dosed rats
Glotzbach, R. K., & Preskorn, S. (1982) · Psychopharmacology · doi:10.1007/bf00470582 · Cited by 111 · see citing works
Self-citation
Pharmacokinetics of the newer antidepressants: Clinical relevance
DeVane, C. L. (1994) · The American Journal of Medicine · doi:10.1016/0002-9343(94)90359-x · Cited by 110 · see citing works
Pharmacokinetics of Selective Serotonin Reuptake Inhibitors: Clinical Relevance
Catterson, M. L., & Preskorn, S. (1996) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1996.tb00206.x · Cited by 107 · see citing works
Self-citation
Metabolic Drug Interactions
Mays, D. C. (2000) · Mayo Clinic Proceedings · doi:10.4065/75.11.1225 · Cited by 103 · see citing works
Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2
Ball, S. E., Ahern, D., Scatina, J., & Kao, J. (1997) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.1997.00591.x · Cited by 103 · see citing works
Venlafaxine: A heterocyclic antidepressant
Ellingrod, V. L., & Perry, P. J. (1994) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/51.24.3033 · Cited by 101 · see citing works
CYP2D6 Inhibition by Fluoxetine, Paroxetine, Sertraline, and Venlafaxine in a Crossover Study: Intraindividual Variability and Plasma Concentration Correlations
Alfaro, C. L., Lam, Y. W., Simpson, J., et al. (2000) · The Journal of Clinical Pharmacology · doi:10.1177/00912700022008702 · Cited by 100 · see citing works
Sequelae after the intravenous injection of three benzodiazepines--diazepam, lorazepam, and flunitrazepam.
Hegarty, J., & Dundee, J. W. (1977) · BMJ · doi:10.1136/bmj.2.6099.1384 · Cited by 97 · see citing works
Effects of several tricyclic antidepressants on the hemodynamics and myocardial contractility of the anesthetized dogs
Jandhyala, B. S., Steenberg, M. L., Perel, J. M., Manian, A. A., & Buckley, J. P. (1977) · European Journal of Pharmacology · doi:10.1016/0014-2999(77)90175-3 · Cited by 97 · see citing works
Coadministration of Nefazodone and Benzodiazepines
Barbhaiya, R. H., Shukla, U., Kroboth, P. D., & Greene, D. S. (1995) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199510000-00003 · Cited by 95 · see citing works
Paroxetine affects metoprolol pharmacokinetics and pharmacodynamics in healthy volunteers
Hemeryck, A., Lefebvre, R. A., DEVRIENDT, C., & Belpaire, F. M. (2000) · Clinical Pharmacology & Therapeutics · doi:10.1067/mcp.2000.104788 · Cited by 95 · see citing works
CYP2D6 Status of Extensive Metabolizers After Multiple-Dose Fluoxetine, Fluvoxamine, Paroxetine, or Sertraline
Alfaro, C. L., Lam, Y. W. F., Simpson, J., & Ereshefsky, L. (1999) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199904000-00011 · Cited by 94 · see citing works
Principles and Practice of Psychopharmacotherapy
Folks, D. G. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0815k · Cited by 93 · see citing works
Toxicity of tricyclic antidepressants--kinetics, mechanism, intervention: a review.
Preskorn, S. H., & Ha, I. (1982) · PubMed · Cited by 93 · see citing works
Self-citation
Recent pharmacologic advances in antidepressant therapy for the elderly.
Preskorn, S. H. (1993) · PubMed · Cited by 90 · see citing works
Self-citation
Rapid cycling depression in adolescence
Spurkland, I., & Vandvik, I. H. (1989) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1989.tb01300.x · Cited by 89 · see citing works
Clinically significant pharmacokinetic drug interactions with psychoactive drugs: antidepressants and antipsychotics and the cytochrome P450 system
Tanaka, E., & Hisawa, S. (1999) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1046/j.1365-2710.1999.00200.x · Cited by 89 · see citing works
Mirtazapine
Sitsen, J. M. A., & Zivkov, M. (1995) · CNS Drugs · doi:10.2165/00023210-199500041-00007 · Cited by 88 · see citing works
Protein Binding Drug Displacement Interactions
MacKichan, J. J. (1989) · Clinical Pharmacokinetics · doi:10.2165/00003088-198916020-00001 · Cited by 87 · see citing works
Citalopram
Gram, L. F., Hansen, M. G. J., Sindrup, S. H., Brøsen, K., Poulsen, J. H., Aaes‐Jørgensen, T., & Overø, K. F. (1993) · Therapeutic Drug Monitoring · doi:10.1097/00007691-199302000-00003 · Cited by 84 · see citing works
Psychiatric Clinics of North America
(2024) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(23)00119-3 · Cited by 84 · see citing works
The α2-selective adrenoceptor antagonist org 3770 (mirtazapine, Remeron®) enhances noradrenergic and serotonergic transmission
de Boer, T., Ruigt, G. S. F., & Berendsen, H. H. G. (1995) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.470100805 · Cited by 82 · see citing works
Characterization of the metabolites of the antidepressant drug nefazodone in human urine and plasma.
Mayol, R. F., Cole, C. A., LUKE, G. M., Colson, K. L., & Kerns, E. H. (1994) · Drug Metabolism and Disposition · doi:10.1016/s0090-9556(25)08374-6 · Cited by 81 · see citing works
Paroxetine potentiates the central nervous system side effects of perphenazine: Contribution of cytochrome P4502D6 inhibition in vivo*
Özdemir, V., Naranjo, C. A., Herrmann, N., Reed, K. L., Sellers, E. M., & KALOW, W. (1997) · Clinical Pharmacology & Therapeutics · doi:10.1016/s0009-9236(97)90037-0 · Cited by 81 · see citing works
Therapeutic Drug Monitoring: Principles and Practice
Preskorn, S., Burke, M. J., & Fast, G. A. (1993) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(18)30167-9 · Cited by 81 · see citing works
Self-citation
In Vitro and In Vivo Studies on the Disposition of Mirtazapine in Humans
Dahl, M., Voortman, G., Alm, C., Elwin, C., Delbressine, L. P. C., Vos, R. M. E., Bogaards, J. J. P., & Bertilsson, L. (1997) · Clinical Drug Investigation · doi:10.2165/00044011-199713010-00005 · Cited by 77 · see citing works
The effect of renal disease on the disposition of venlafaxine
Troy, S. M., Schultz, R. W., Parker, V. D., Chiang, S. T., & Blum, R. A. (1994) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1994.95 · Cited by 76 · see citing works
Isoniazid-Induced Carbamazepine Toxicity and Vice Versa
Wright, J. M., Stokes, E. F., & Sweeney, V. P. (1982) · New England Journal of Medicine · doi:10.1056/nejm198211183072107 · Cited by 75 · see citing works
A fixed-dose (300 mg) efficacy study of bupropion and placebo in depressed outpatients.
Lineberry, C. G., Ja, J., Rn, R., SAMARA, B., Feighner, J. P., Harto-Truax, N., Granacher, R. P., Weisler, R. H., Js, C., & Wf, B. (1990) · PubMed · Cited by 75 · see citing works
Influence of gender on the pharmacokinetics and pharmacodynamics of drugs.
Thürmann, P., & Hompesch, B. C. (1998) · PubMed · Cited by 73 · see citing works
DANGER OF MAOI THERAPY AFTER FLUOXETINE WITHDRAWAL
Sternbach, H. A. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92812-7 · Cited by 70 · see citing works
Fluoxetine Pharmacokinetics and Effect on CYP2C19 in Young and Elderly Volunteers
Harvey, A. T., & Preskorn, S. (2001) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-200104000-00007 · Cited by 69 · see citing works
Self-citation
Recent Developments in Drug Metabolism of Relevance to Psychiatrists
Pollock, B. G. (1994) · Harvard Review of Psychiatry · doi:10.3109/10673229409017138 · Cited by 68 · see citing works
Cardiovascular Effects of Antidepressant Medications
Halper, J. P., & Mann, J. J. (1988) · The British Journal of Psychiatry · doi:10.1192/s0007125000297341 · Cited by 66 · see citing works
CYP2D6 Inhibition in Patients Treated With Sertraline
Sproule, B. A., Otton, S. V., Cheung, S. W., Zhong, X. H., Romach, M. K., & Sellers, E. M. (1997) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199704000-00007 · Cited by 64 · see citing works
The effect of sertraline on the pharmacokinetics of desipramine and imipramine
Kurtz, D. L., Bergstrom, R. F., Goldberg, M. J., & Cerimele, B. J. (1997) · Clinical Pharmacology & Therapeutics · doi:10.1016/s0009-9236(97)90062-x · Cited by 64 · see citing works
Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation
Abernethy, D. R. (2001) · Clinical Pharmacology & Therapeutics · doi:10.1067/mcp.2001.114230 · Cited by 63 · see citing works
Combined Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Cytochrome P450 2B6 Substrates and Protein Homology Modeling
Wang, Q., & Halpert, J. R. (2002) · Drug Metabolism and Disposition · doi:10.1124/dmd.30.1.86 · Cited by 62 · see citing works
The Effects of Estrogen, Progesterone, and Ionized Calcium on Seizures During the Menstrual Cycle of Epileptic Women
Jacono, J. J., & Robertson, J. M. D. (1987) · Epilepsia · doi:10.1111/j.1528-1157.1987.tb03690.x · Cited by 62 · see citing works
Fluvoxamine
Palmer, K. J., & Benfield, P. (1994) · CNS Drugs · doi:10.2165/00023210-199401010-00006 · Cited by 62 · see citing works
Coadministration of Nefazodone and Benzodiazepines
Greene, D. S., Salazar, D. E., Dockens, R. C., Kroboth, P. D., & Barbhaiya, R. H. (1995) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199512000-00003 · Cited by 61 · see citing works
Clinical valproate toxicity induced by acetylsalicylic acid
Goulden, K. J., Dooley, J. M., CAMFIELD, P. R., & Fraser, A. D. (1987) · Neurology · doi:10.1212/wnl.37.8.1392 · Cited by 60 · see citing works
Effects of Trazodone and Fluoxetine in the Treatment of Major Depression
Maes, M. H. J., Westenberg, H. G. M., Vandoolaeghe, E., Demedts, P., Wauters, A., Neels, H. M., & Meltzer, H. Y. (1997) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199710000-00004 · Cited by 60 · see citing works
Evaluation of Bupropion Hydrochloride: The First of a New Class of Atypical Antidepressants
Preskorn, S., & Othmer, S. C. (1984) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/j.1875-9114.1984.tb03306.x · Cited by 59 · see citing works
Self-citation
Pharmacokinetic Optimisation of Therapy with Newer Antidepressants
Goodnick, P. J. (1994) · Clinical Pharmacokinetics · doi:10.2165/00003088-199427040-00005 · Cited by 58 · see citing works
Preliminary studies of the kinetics of citalopram in man
Over�, K. F. (1978) · European Journal of Clinical Pharmacology · doi:10.1007/bf00560260 · Cited by 58 · see citing works
Interaction of indomethacin and ibuprofen with lithium in manic patients under a steady-state lithium level.
Ragheb, M. A., Ban, T. A., Buchanan, D., & Frölich, J. C. (1980) · PubMed · Cited by 56 · see citing works
Age Effects on Alpha‐1‐Acid Glycoprotein Concentration and Imipramine Plasma Protein Binding
Abernethy, D. R., & Kerzner, L. J. (1984) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1984.tb04167.x · Cited by 55 · see citing works
The pharmacokinetics of paroxetine in renal impairment
Doyle, G. D., Laher, M. S., Kelly, J. G., Byrne, M. M., Clarkson, A., & Zussman, B. D. (1989) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1989.tb07181.x · Cited by 55 · see citing works
Pharmacokinetic considerations of antidepressant use in the elderly.
DeVane, C. L., & Pollock, B. G. (1999) · PubMed · Cited by 55 · see citing works
Amitriptyline plasma protein binding: Effect of plasma pH and relevance to clinical overdose
Levitt, M. A., Sullivan, J. B., Owens, S. M., Burnham, L., & Finley, P. R. (1986) · The American Journal of Emergency Medicine · doi:10.1016/0735-6757(86)90155-5 · Cited by 54 · see citing works
A Study of the Effect of Age and Gender on the Pharmacokinetics of Nefazodone After Single and Multiple Doses
Barbhaiya, R. H., Buch, A., & Greene, D. S. (1996) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199602000-00004 · Cited by 54 · see citing works
Neuroendocrine and behavioral responses to intravenous m- chlorophenylpiperazine (mCPP) in depressed patients and healthy comparison subjects
Anand, A., Charney, D. S., Delgado, P. L., McDougle, C. J., Heninger, G. R., & Price, L. H. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.11.1626 · Cited by 54 · see citing works
Bioavailability of mirtazapine from Remeron® tablets after single and multiple oral dosing
Voortman, G., & Paanakker, J. E. (1995) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.470100803 · Cited by 53 · see citing works
Cytochrome P450 Enzymes
Harvey, A. T., & Preskorn, S. (1996) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199610000-00002 · Cited by 53 · see citing works
Self-citation
Antidepressant response and plasma concentrations of bupropion.
Preskorn, S. (1983) · PubMed · Cited by 52 · see citing works
Self-citation
Nonlinear Pharmacokinetics of Nefazodone After Escalating Single and Multiple Oral Doses
Kaul, S., Shukla, U., & Barbhaiya, R. H. (1995) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1995.tb04127.x · Cited by 51 · see citing works
Interactions between cyclosporine and newer antidepressant medications
Vella, J. P., & Sayegh, M. (1998) · American Journal of Kidney Diseases · doi:10.1053/ajkd.1998.v31.pm9469504 · Cited by 51 · see citing works
Pharmacokinetic dose-proportionality study at steady state of mirtazapine from Remeron® tablets
Timmer, C. J., Lohmann, A., & Mink, C. P. A. (1995) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.470100804 · Cited by 51 · see citing works
Paroxetine shifts imipramine metabolism
Albers, L. J., Reist, C., Helmeste, D. M., Vu, R., & Tang, S. W. (1996) · Psychiatry Research · doi:10.1016/0165-1781(95)02822-6 · Cited by 51 · see citing works
Nefazodone and cyclosporine drug–drug interaction
Wright, D. H., Lake, K. D., Bruhn, P. S., & Emery, R. W. (1999) · The Journal of Heart and Lung Transplantation · doi:10.1016/s1053-2498(98)00036-9 · Cited by 49 · see citing works
Effect of Sertraline on Protein Binding of Warfarin
Apseloff, G., Wilner, K. D., Gerber, N., & Tremaine, L. M. (1997) · Clinical Pharmacokinetics · doi:10.2165/00003088-199700321-00006 · Cited by 49 · see citing works
Effect of Sertraline on Plasma Nortriptyline Levels in Depressed Elderly
Solai, L. K., Mulsant, B. H., Pollock, B. G., Sweet, R. A., Rosen, J., Yu, K., & Reynolds, C. F. (1997) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v58n1006 · Cited by 48 · see citing works
Effect of Venlafaxine versus Fluoxetine on Metabolism of Dextromethorphan, a CYP2D6 Probe
Amchin, J., Ereshefsky, L., Zarycranski, W., Taylor, K. P., Albano, D., & Klockowski, P. M. (2001) · The Journal of Clinical Pharmacology · doi:10.1177/00912700122010159 · Cited by 48 · see citing works
Pharmacokinetic Optimisation of Drug Therapy in Elderly Patients
Parker, B. M., Cusack, B. J., & Vestal, R. E. (1995) · Drugs & Aging · doi:10.2165/00002512-199507010-00002 · Cited by 47 · see citing works
Antidepressant interactions with warfarin
Duncan, D. P., Sayal, K. S., McConnell, H., & Taylor, D. M. (1998) · International Clinical Psychopharmacology · doi:10.1097/00004850-199803000-00006 · Cited by 46 · see citing works
Protein binding and disposition of lignocaine in the elderly
Cusack, B. J., O'MALLEY, K., Lavan, J. N., Noel, J., & Kelly, J. G. (1985) · European Journal of Clinical Pharmacology · doi:10.1007/bf00544089 · Cited by 46 · see citing works
Plasma levels of amitriptyline: effect of age and sex.
Preskorn, S. H., & Ds, M. (1985) · PubMed · Cited by 46 · see citing works
Self-citation
Effect of age on pharmacokinetics and pharmacodynamics in man.
Klotz, U. E. (1998) · PubMed · Cited by 46 · see citing works
Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O‐ and N‐demethylation
Schmider, J., Greenblatt, D. J., Moltke, L. L., Harmatz, J. S., & Shader, R. I. (1996) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.1996.30512.x · Cited by 43 · see citing works
Cytochromes in Psychopharmacology
&NA; (1994) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199402000-00001 · Cited by 42 · see citing works
A Possible Bupropion and Imipramine Interaction
Shad, M. U., & Preskorn, S. (1997) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199704000-00011 · Cited by 41 · see citing works
Self-citation
Cytochromes in psychopharmacology.
Ll, V. M., Dj, G., Js, H., et al. (1994) · PubMed · Cited by 41 · see citing works
Effects of aspirin on salivary and serum phenytoin kinetics in healthy subjects
Paxton, J. W. (1980) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1980.26 · Cited by 40 · see citing works
Serotonin Syndrome Induced by Fluvoxamine and Mirtazapine
Demers, J. C., & Malone, M. (2001) · Annals of Pharmacotherapy · doi:10.1345/aph.10418 · Cited by 40 · see citing works
Effect of venlafaxine on the pharmacokinetics of alprazolam.
Amchin, J., Zarycranski, W., Taylor, K. P., Albano, D., & Klockowski, P. M. (1998) · PubMed · Cited by 39 · see citing works
Effect of Venlafaxine on the Pharmacokinetics of Risperidone
Amchin, J., Zarycranski, W., Taylor, K. P., Albano, D., & Klockowski, P. M. (1999) · The Journal of Clinical Pharmacology · doi:10.1177/009127009903900314 · Cited by 39 · see citing works
Metabolism and Pharmacokinetics of Phenelzine
Robinson, D. S., Cooper, T. B., Jindal, S. P., CORCELLA, J., & LUTZ, T. (1985) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-198505060-00005 · Cited by 39 · see citing works
Tricyclic antidepressants: the whys and hows of therapeutic drug monitoring.
Preskorn, S. H. (1989) · PubMed · Cited by 39 · see citing works
Self-citation
Therapeutic receptor-blocking concentrations of neuroleptics
Seeman, P. M. (1995) · International Clinical Psychopharmacology · doi:10.1097/00004850-199509000-00002 · Cited by 38 · see citing works
P‐glycoprotein Interactions of Nefazodone and Trazodone in Cell Culture
Störmer, E., Moltke, L. L., Perloff, M. D., & Greenblatt, D. J. (2001) · The Journal of Clinical Pharmacology · doi:10.1177/00912700122010609 · Cited by 37 · see citing works
Overdose and Safety with Fluvoxamine
Henry, J. A. (1991) · International Clinical Psychopharmacology · doi:10.1097/00004850-199112003-00004 · Cited by 37 · see citing works
Interaction Between Tacrolimus and Nefazodone in a Stable Renal Transplant Recipient
Olyaei, A. J., DEMATTOS, A. M., Norman, D. J., & Wm, B. (1998) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/j.1875-9114.1998.tb03160.x · Cited by 35 · see citing works
The effects of renal and hepatic disease on the pharmacokinetics, renal tolerance, and risk-benefit profile of fluoxetine
Bergstrom, R. F., Beasley, C. M., Levy, N. B., Blumenfield, M., & Lemberger, L. (1993) · International Clinical Psychopharmacology · doi:10.1097/00004850-199300840-00009 · Cited by 35 · see citing works
Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study
LOONEN, A. J. M., DOORSCHOT, C. H., Oostelbos, M. C. J. M., & Sitsen, J. M. A. (1999) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(99)00054-1 · Cited by 34 · see citing works
NOVEL SEROTONERGIC MECHANISMS AND CLINICAL EXPERIENCE WITH NEFAZODONE
FONTAINE, R. (1992) · Clinical Neuropharmacology · doi:10.1097/00002826-199201001-00054 · Cited by 33 · see citing works
Acetylation phenotype, platelet monoamine oxidase inhibition, and the effectiveness of phenelzine in depression
Davidson, J. R. T., McLeod, M. N., & Blum, M. R. (1978) · American Journal of Psychiatry · doi:10.1176/ajp.135.4.467 · Cited by 33 · see citing works
Effect of Venlafaxine on CYP1A2‐Dependent Pharmacokinetics and Metabolism of Caffeine
Amchin, J., Zarycranski, W., Taylor, K. P., Albano, D., & Klockowski, P. M. (1999) · The Journal of Clinical Pharmacology · doi:10.1177/009127009903900308 · Cited by 32 · see citing works
Debate resolved: there are differential effects of serotonin selective reuptake inhibitors on cytochrome P450 enzymes
Preskorn, S. (1998) · Journal of Psychopharmacology · doi:10.1177/0269881198012003051 · Cited by 31 · see citing works
Self-citation
Pharmacokinetic interactions of antidepressants.
Richelson, E. (1998) · PubMed · Cited by 30 · see citing works
Should bupropion dosage be adjusted based upon therapeutic drug monitoring?
Preskorn, S. H. (1991) · PubMed · Cited by 30 · see citing works
Self-citation
The Extent and Determinants of Changes in CYP2D6 and CYP1A2 Activities With Therapeutic Doses of Sertraline
Özdemir, V., Naranjo, C. A., Herrmann, N., Shulman, R. W., Sellers, E. M., Reed, K. L., & KALOW, W. (1998) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199802000-00009 · Cited by 30 · see citing works
Tacrolimus Toxic Reaction Associated With the Use of Nefazodone: Paroxetine as an Alternative Agent
Campo, J. V., Smith, C., & Perel, J. M. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.11.1050-a · Cited by 28 · see citing works
Clinically Significant Carbamazepine Drug Interactions: An Overview
Pippenger, C. E. (1987) · Epilepsia · doi:10.1111/j.1528-1157.1987.tb05781.x · Cited by 27 · see citing works
Metabolism and Pharmacokinetics of Phenelzine
Robinson, D. S., Cooper, T. B., Jindal, S. P., et al. (1985) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-198512000-00005 · Cited by 27 · see citing works
Nonlinear desipramine kinetics: Prevalence and importance
Nelson, J. C., & Jatlow, P. I. (1987) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1987.93 · Cited by 26 · see citing works
Blood levels and acute response to bupropion
Goodnick, P. J. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.3.399 · Cited by 25 · see citing works
Single- and multiple-dose pharmacokinetics of nefazodone in patients with hepatic cirrhosis
Barbhaiya, R. H., Shukla, U., Natarajan, C. S., Behr, D., Greene, D. S., & Sainati, S. M. (1995) · Clinical Pharmacology & Therapeutics · doi:10.1016/0009-9236(95)90051-9 · Cited by 25 · see citing works
Pharmacokinetic and Pharmacodynamic Evaluation of Warfarin and Nefazodone Coadministration in Healthy Subjects
Salazar, D. E., Dockens, R. C., Milbrath, R. L., Raymond, R. H., Fulmor, I. E., Chaikin, P., & Uderman, H. D. (1995) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1995.tb04114.x · Cited by 25 · see citing works
Psychotropic drugs and alcohol: Pharmacokinetic and pharmaco dynamic interactions
Weller, R. A., & Preskorn, S. (1984) · Psychosomatics · doi:10.1016/s0033-3182(84)73047-7 · Cited by 24 · see citing works
Self-citation
NEFAZODONE AND CYP450 3A4 INTERACTIONS WITH CYCLOSPORINE AND TACROLIMUS1
Garton, T. (2002) · Transplantation · doi:10.1097/00007890-200209150-00028 · Cited by 24 · see citing works
Fluvoxamine Augmentation Increases Serum Mirtazapine Concentrations Three- to Fourfold
Anttila, S. A. K., Rasanen, I., & Leinonen, E. V. J. (2001) · Annals of Pharmacotherapy · doi:10.1345/aph.1a014 · Cited by 23 · see citing works
Nefazodone pharmacokinetics: assessment of nonlinearity, intra-subject variability and time to attain steady-state plasma concentrations after dose escalation and de-escalation
Barbhaiya, R. H., Shukla, U., Chaikin, P., Greene, D. S., & Marathe, P. (1996) · European Journal of Clinical Pharmacology · doi:10.1007/s002280050076 · Cited by 20 · see citing works
PHARMACOGENETICS OF TRICYCLIC AND NOVEL ANTIDEPRESSANTS: RECENT DEVELOPMENTS
Brøsen, K., Gram, L. F., Sindrup, S. H., Skjelbo, E., & Nielsen, K. K. (1992) · Clinical Neuropharmacology · doi:10.1097/00002826-199201001-00043 · Cited by 20 · see citing works
Antidepressants, Metabolites, and Apparent Drug Resistance
Potter, W. Z., & Manji, H. K. (1990) · Clinical Neuropharmacology · doi:10.1097/00002826-199001001-00005 · Cited by 20 · see citing works
Drug Approvals and Withdrawals Over the Last 60 Years
Preskorn, S. (2002) · Journal of Psychiatric Practice · doi:10.1097/00131746-200201000-00006 · Cited by 17 · see citing works
Self-citation
Cytochrome P-450 Monooxygenases and Interactions of Psychotropic Drugs
Shen, W. W., & Lin, K. (1991) · The International Journal of Psychiatry in Medicine · doi:10.2190/u0bd-pvhw-ba01-a1d0 · Cited by 17 · see citing works
Nortriptyline toxicity secondary to interaction with bupropion sustained-release
Weintraub, D. A. (2001) · Depression and Anxiety · doi:10.1002/1520-6394(2001)13:1 · Cited by 16 · see citing works
Effect of venlafaxine on the pharmacokinetics of terfenadine.
Amchin, J., Zarycranski, W., Taylor, K. P., Albano, D., & Klockowski, P. M. (1998) · PubMed · Cited by 16 · see citing works
Central Nervous System Drugs
Baumann, P., & Hiemke, C. (2012) · doi:10.1002/9783527630905.ch11 · Cited by 15 · see citing works
Hemoperfusion for Imipramine Overdose: Elimination of Active Metabolites
Pentel, P. R., Bullock, M. L., & DeVane, C. L. (1982) · Journal of Toxicology Clinical Toxicology · doi:10.3109/15563658209025728 · Cited by 15 · see citing works
Lithium toxicity induced by triamterene-hydrochlorothiazide
Mehta, B., & Robinson, B. H. (1980) · Postgraduate Medical Journal · doi:10.1136/pgmj.56.661.783 · Cited by 14 · see citing works
Influence of hepatic impairment on the pharmacokinetics of nefazodone and two of its metabolites after single and multiple oral doses
Ferry, N., Bernard, N., Cuisinaud, G., Rougier, P., TREPO, C. G., & Sassard, J. (1994) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.1994.tb00827.x · Cited by 14 · see citing works
Evaluation of the development of acute tolerance to the psychomotor effects of midazolam following intravenous infusions in healthy volunteers
Fleishaker, J. C., Chambers, J. H., & Peters, G. R. (1995) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.470100204 · Cited by 13 · see citing works
Lack of an effect of nefazodone on the pharmacokinetics and pharmacodynamics of theophylline during concurrent administration in patients with chronic obstructive pulmonary disease.
Dockens, R. C., Rapoport, D. M., Roberts, D., Greene, D. S., & Barbhaiya, R. H. (1995) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1995.tb05806.x · Cited by 13 · see citing works
The debate over substitution policy: Its evolution and scientific basis
Schwartz, L. L. (1985) · The American Journal of Medicine · doi:10.1016/0002-9343(85)90584-4 · Cited by 12 · see citing works
Steady-state pharmacokinetics of nefazodone in subjects with normal and impaired renal function
Barbhaiya, R. H., Brady, M. E., Shukla, U., & Greene, D. S. (1995) · European Journal of Clinical Pharmacology · doi:10.1007/bf00192384 · Cited by 12 · see citing works
The Effect of Nefazodone on the Single-Dose Pharmacokinetics of Phenytoin in Healthy Male Subjects
Marino, M. R., Langenbacher, K. M., Hammett, J. L., Nichola, P. S., & Uderman, H. D. (1997) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199702000-00006 · Cited by 11 · see citing works
Principles to optimize drug treatment in the depressed elderly: practical pharmacokinetics and drug interactions.
Lj, C. (1995) · PubMed · Cited by 8 · see citing works
Psychiatry's role in the dehumanization of health care.
Fink, E. B. (1982) · PubMed · Cited by 7 · see citing works
The Effect of Age on Plasma Levels of Nortriptyline
BUPP, S. J., & Preskorn, S. (1991) · Annals of Clinical Psychiatry · doi:10.3109/10401239109147969 · Cited by 7 · see citing works
Self-citation
The Importance of Presystemic Extraction in Clinical Psychopharmacology
Greenblatt, D. J., Moltke, L. L., & Shader, R. I. (1996) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199612000-00001 · Cited by 6 · see citing works
Diagnosis and treatment of depression in medical practice.
Nemeroff, C. B. (1993) · PubMed · Cited by 5 · see citing works
Principles and Practice of Psychopharmacotherapy, 3rd Edition
Schoenbachler, B. (2002) · Addictive Disorders & Their Treatment · doi:10.1097/00132576-200209000-00005 · Cited by 2 · see citing works
Drug Metabolism and Psychiatry: Preface
Baker, G. B. (1999) · Cellular and Molecular Neurobiology · doi:10.1023/a:1006941614219 · Cited by 2 · see citing works

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Crankshaw, D. P., & Beemer, G. H. (1991) · Baillière s Clinical Anaesthesiology · doi:10.1016/s0950-3501(05)80192-8 · Cited by 3 · see citing works
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Struys, M., Kalmar, A., & De Paepe, P. (2006) · Wiley eBooks · doi:10.1002/9780470755297 · Cited by 1 · see citing works
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References
(1990) · Elsevier eBooks · doi:10.1016/b978-0-7236-0913-1.50012-8
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Authors: Preskorn, S. H., & Catterson, M. L.
Affiliations: University of Kansas (US)
Corresponding author: Preskorn, S. H.
Venue: Handbook of Experimental Pharmacology
Publisher: Springer Berlin Heidelberg
Published: 2004
Pages: 35-86
ISSN: 0171-2004 (ISSN-L)
1865-0325
DOI: 10.1007/978-3-642-18500-7_2
OpenAlex: W206325618
Cited by: 14
References: 187
Citations by year: 2025: 1 · 2024: 1 · 2022: 1 · 2021: 1 · 2020: 2 · 2018: 1
FWCI: 4.12
Type: book chapter
Language: en
Open access: closed
Locations: Handbook of experimental pharmacology (publishedVersion)
Topics: Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Health Sciences › Medicine › Pharmacology › Antibiotics Pharmacokinetics and Efficacy
Keywords: pharmacokinetics, antidepressants, drug absorption, drug distribution, drug metabolism, drug elimination, half-life, steady-state concentration, linear pharmacokinetics, nonlinear pharmacokinetics, protein binding, drug-drug interactions, tricyclic antidepressants, selective serotonin reuptake inhibitors, bupropion, serotonin-norepinephrine reuptake inhibitors, venlafaxine, duloxetine, trazodone, nefazodone, monoamine oxidase inhibitors, mirtazapine

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