The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Succinct de Bruijn Graphs
Open accessAbstract
We propose a new succinct de Bruijn graph representation. If the de Bruijn graph of k-mers in a DNA sequence of length N has m edges, it can be represented in 4m+o(m) bits. This is much smaller than existing ones. The numbers of outgoing and incoming edges of a node are computed in constant time, and the outgoing and incoming edge with given label are found in constant time and $\mathcal{O}(k)$ time, respectively. The data structure is constructed in $\mathcal{O}(Nk \log m/\log\log m)$ time using no additional space.
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Cites
De novo assembly of human genomes with massively parallel short read sequencing
Li, R., Zhu, H., Ruan, J., Qian, W., Fang, X., Shi, Z., Li, Y., Li, S., Shan, G., Kristiansen, K., et al. (2010) · Genome Research · doi:10.1101/gr.097261.109 · Cited by 2,926 · cited 3×
“Most modern assembler programs use this paradigm [12, 13, 14, 15, 16, 17, 18, 19].”
BackgroundMethodThe Human Genome Project: Lessons from Large-Scale Biology
Collins, F. S., Morgan, M., & Patrinos, A. (2003) · Science · doi:10.1126/science.1084564 · Cited by 1,284
How to apply de Bruijn graphs to genome assembly
Compeau, P. E. C., Pevzner, P. A., & Tesler, G. (2011) · Nature Biotechnology · doi:10.1038/nbt.2023 · Cited by 673
Cited by
Eizenga, J. M., Novak, A. M., Sibbesen, J. A., Heumos, S., Ghaffaari, A., Hickey, G., Chang, X., Seaman, J. D., Rounthwaite, R., Ebler, J., et al. (2020) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-120219-080406 · Cited by 320
Indexing Graphs for Path Queries with Applications in Genome Research
Siren, J., Valimaki, N., & Makinen, V. (2014) · IEEE/ACM Transactions on Computational Biology and Bioinformatics · doi:10.1109/tcbb.2013.2297101 · Cited by 324
A Review of bioinformatics tools for bio-prospecting from metagenomic sequence data
Roumpeka, D. D., Wallace, R. J., Escalettes, F., Fotheringham, I., & Watson, M. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00023 · Cited by 199
“Megahit (Li et al., 2015) uses a very similar approach to IDBA-UD, but takes advantage of succinct de Bruijn graphs (Bowe et al., 2012) and GPUs, which lowers the memory requirements and increases speed, respectively.”
MethodScalable pairwise whole-genome homology mapping of long genomes with BubbZ
Minkin, I., & Medvedev, P. (2020) · iScience · doi:10.1016/j.isci.2020.101224 · Cited by 15
Farruggia, A., Gagie, T., Navarro, G., Puglisi, S. J., & Sirén, J. (2018) · The Computer Journal · doi:10.1093/comjnl/bxx108 · Cited by 14
Metadata
- Authors
- Bowe, A., Onodera, T., Sadakane, K., & Shibuya, T.
- Venue
- Lecture Notes in Computer Science
- Publisher
- Springer Berlin Heidelberg
- Published
- 2012
- Pages
- 225-235
- ISSN
- 0302-9743 (ISSN-L)
- 1611-3349
- OpenAlex
- W6247929
- Cited by
- 167
- References
- 3
- FWCI
- 6.40
- Type
- conference paper
- Language
- en
- Open access
- green
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