Tissue Response to Resorbable Synthetic Polymers
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As PLA/PGA material degrades, small particles that break off are phagocytized by macrophages and multinucleated giant cells.
“It has been shown that as the material degrades the small particles that break off are phagocytized by macrophages and multinucleated giant cells”
From Biodegradable synthetic polymers for tissue engineering (2003) · cites this paper as Gibbons, 1992
Cites
<i>In vivo</i> and <i>in vitro</i> degradation of glycine/DL‐lactic acid copolymers
Schakenraad, J. M., Nieuwenhuis, P., Molenaar, I., Helder, J., Dijkstra, P. J., & Feijen, J. (1989) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820231105 · Cited by 101 · see citing works
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Biodegradable synthetic polymers for tissue engineering
CSIRO Molecular Science, B. 1., & Gunatillake, P. (2003) · European Cells and Materials · doi:10.22203/ecm.v005a01 · Cited by 1,765 · see citing works
“It has been shown that as the material degrades the small particles that break off are phagocytized by macrophages and multinucleated giant cells (Gibbons, 1992).”
BackgroundKang, E. Y., Lih, E., Kim, I. H., Joung, Y. K., & Han, D. K. (2016) · Biomaterials Research · doi:10.1186/s40824-016-0054-6 · Cited by 38 · see citing works
- Authors
- Gibbons, D. F.
- Affiliations
- 3M (United States) (US)
- Corresponding author
- Gibbons, D. F.
- Venue
- Degradation Phenomena on Polymeric Biomaterials
- Publisher
- Springer Berlin Heidelberg
- Published
- 1992
- Pages
- 97-105
- OpenAlex
- W980520588
- Cited by
- 31
- References
- 1
- Citations by year
- 2023: 1 · 2021: 1 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 4 · 2015: 1 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 5.09
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Springer eBooks (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Keywords
- tissue reaction, biodegradation, chronic inflammation, macrophages, cytokines, interleukins, growth factors, phagocytosis, biocompatibility
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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