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In Vitro Studies
Abstract
The most frequent pathogens encountered in urologic surgery are Gram-negative bacteria (Table 1). In a hospital setting, E. coli is still the predominant pathogen, but bacteria that are difficult to treat such as Proteus mirabilis and Pseudomonas aeruginosa are found with increasing frequency. Third-generation cephalosporins have been widely used for prophylaxis as they have a favorable antimicrobial action and low toxicity (McEniry and Gorbach, 1987). The MIC against most uropathogens is well below 1 mg/L for most thirdgeneration cephalosporins. Likewise, quinolones have a very broad antimicrobial spectrum against most uropathogens and some are active against Pseudomonas aeruginosa, Staphylococcus aureus, Mycoplasma and Chlamydia trachomatis (Hooper and Wolfson, 1991; Nielsen and Madsen, 1989). Moreover, the quinolone MIC against many of these bacteria is very low (see Table 3 and section 2.4.1). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Lopes, M. S., Jardini, A. L., & Filho, R. M. (2012) · Procedia Engineering · doi:10.1016/j.proeng.2012.07.534 · Cited by 457
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Metadata
- Authors
- Gasser, T. C.
- Venue
- Fortschritte der Urologie und Nephrologie
- Publisher
- Steinkopff
- Published
- 1992
- Pages
- 12-12
- ISSN
- 0071-7975 (ISSN-L)
- OpenAlex
- W216844364
- Cited by
- 493
- References
- 0
- FWCI
- 40.95
- Type
- book chapter
- Language
- de
- Open access
- closed
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