PEGylated Protein Drugs: Basic Science and Clinical Applications

PEGylation of an osteoclast inhibitory peptide: Suitable candidate for the treatment of osteoporosis

Akhtar, J., Mallaredy, V., Dandapat, J., Maiti, P. K., Sahoo, S. K., & Singh, S. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.06.012 · Cited by 3

Synthesis and Pharmacological Properties of Linear Poly(Ethylene Glycol)s Conjugated to Interferon α-2b by Azo Coupling

Sheremet’ev, S. V., Лоншаков, Д. В., Korovkin, S. A., Белослудцева, Е. М., Катлинский, А. В., Semchenko, A. V., & Borisova, O. V. (2017) · Pharmaceutical Chemistry Journal · doi:10.1007/s11094-017-1532-4 · Cited by 3

End Point Versus Backbone Specificity Governs Characteristics of Antibody Binding to Poly(ethylene glycol) Brushes

Latza, V. M., Rodriguez-Loureiro, I., Fragneto, G., & Schneck, E. (2018) · Langmuir · doi:10.1021/acs.langmuir.8b02774 · Cited by 3

Polyethylene glycol and its derivatives as environmental sustainable corrosion inhibitors: A literature survey

Verma, C., & Hussain, C. M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85405-4.00005-7 · Cited by 3

review on impact of pegylation on biopharmaceuticals

Gundecha, S., Shirolkar, S. V., Deshkar, S., Chitlange, S. S., Shewale, S., & Jagtap, R. A. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns3.7477 · Cited by 3

The pharmacokinetics of peginterferon lambda‐1a following single dose administration to subjects with impaired renal function

Hruska, M. W., Adamczyk, R., Colston, E., Hesney, M., Stonier, M., Myler, H. A., & Bertz, R. (2015) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12634 · Cited by 3

PEGylation of human coagulation factor VIII and other plasma proteins

Siekmann, J., & Turecek, P. L. (2019) · Elsevier eBooks · doi:10.1016/b978-0-444-64081-9.00008-5 · Cited by 3

PEGylation near a Patch of Nonpolar Surface Residues Increases the Conformational Stability of the WW Domain

Draper, S. R. E., Ashton, D. S., Conover, B. M., Carter, A. J., Stern, K. L., Xiao, Q., & Price, J. L. (2019) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.9b02615 · Cited by 3

Anti-infectives

Mohamed-Ahmed, A. H. A., Ginn, C., Croft, S. L., & Brocchini, S. (2013) · Springer eBooks · doi:10.1007/978-1-4614-9164-4_16 · Cited by 3

Injectable non-immunogenic PEG-like conjugate that forms a subcutaneous depot and enables sustained delivery of a peptide drugPreprint

Özer, İ., Slezak, A., Everitt, J. I., Li, X., Zakharov, N., Collier, J. H., Campbell, J. E., D’Alessio, D. A., & Chilkoti, A. (2021) · Research Square · doi:10.21203/rs.3.rs-737658/v1 · Cited by 3

PEGylation of Therapeutic Proteins and Peptides

Akojwar, N., Mishra, A., Mishra, P., Tekade, M., Mule, S. R., & Tekade, R. K. (2025) · Springer eBooks · doi:10.1007/978-981-97-7316-9_11 · Cited by 2

Stability and Pharmacological Effects of Gene-Recombinant Wild Type and Mutant Human Adrenocorticotropic Hormone

Huang, Y., Pei, Y., Guan, H., Wei, S., Wu, H., Zhou, Y., Pei, J., Chen, L., Wang, Y., Chen, Y., et al. (2017) · Pharmaceutical Research · doi:10.1007/s11095-017-2107-5 · Cited by 2

Effect of Pegylation on Self-Association of IFN-α2b

Mohs, A., Ambrogelly, A., Yang, X., Haverick, M. A., Cheung, J. K., Narasimhan, C. N., & Shameem, M. (2013) · Molecular Pharmaceutics · doi:10.1021/mp400343b · Cited by 2

Protein PEGylation

Veronese, F. M., & Pasut, G. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0554-2_15 · Cited by 2

Production of PEGylated Proteins

Fee, C. J., & Damodaran, V. B. (2012) · doi:10.1002/9783527653096.ch7 · Cited by 2

Meta-Analysis of Polyethylene Glycol and Cellulose-based Polymers in Vaccine and Drug Delivery: A Comprehensive ReviewPreprint

Aldaais, E. A. (2023) · Preprints.org · doi:10.20944/preprints202308.0228.v1 · Cited by 2

Innovative coating technologies for transdermal microarray patches

Ali, M., Zhu, J., Ye, J., Liu, Z., & Mohammed, Y. (2025) · Surfaces and Interfaces · doi:10.1016/j.surfin.2025.107598 · Cited by 1

Study of pH-Dependent Kinetics of Filgrastim Pegylation with Succinimide Derivatives of Poly(Ethylene Glycol) and Comparison of the Properties of Pegylated Forms Obtained Under Various Conditions

Лоншаков, Д. В., Sheremet’ev, S. V., Хурсевич, Е. М., Бобрышева, И. В., Grebennikova, O. A., & Korovkin, S. A. (2024) · Pharmaceutical Chemistry Journal · doi:10.1007/s11094-024-03147-5 · Cited by 1

Formulation Approaches and Strategies for PEGylated Biotherapeutics

Pak, R. H., & Finn, R. F. (2013) · AAPS advances in the pharmaceutical sciences series · doi:10.1007/978-1-4614-7978-9_4 · Cited by 1

Immunogenicity assessment of PEGylated proteins, Lonquex, a PEGylated G-CSF case study

Zou, L., & Nock, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-444-64081-9.00006-1 · Cited by 1

Design and evaluation of novel thrombin-based GLP-1 analogs with peptidic albumin binding domain for the controlled release of GLP-1

Niu, X., Nong, S., Zhang, X., Li, X., Wang, C., Li, W., & Zhou, T. (2020) · RSC Advances · doi:10.1039/d0ra00104j · Cited by 1

Recent advances in protein drug delivery

Wang, Q. (2020) · IOP Conference Series Materials Science and Engineering · doi:10.1088/1757-899x/768/5/052055 · Cited by 1

Allergic Reactions Caused by a COVID-19 Vaccine

Sugiura, K., & Sugiura, M. (2021) · Emergency Medicine Investigations · doi:10.29011/2475-5605.010113

Synthesis and Pharmacological Properties of the Azo-Conjugate of Erythropoietin β with Poly(Ethylene Glycol)

Sheremet’ev, S. V., Лоншаков, Д. В., Белослудцева, Е. М., Borisova, O. V., Sidorova, A. V., & Kalinskii, A. V. (2021) · Pharmaceutical Chemistry Journal · doi:10.1007/s11094-021-02480-3 · Cited by 1

Polyvinylalkohol als biokompatibles Polymer zur Passivierung von Goldnanostäbchen

Kinnear, C., Burnand, D., Clift, M. J. D., Kilbinger, A. F. M., Rothen‐Rutishauser, B., & Petri‐Fink, A. (2014) · Angewandte Chemie · doi:10.1002/ange.201404100

For Review. Confidential - ACS

Gidley, M. J., & Fillery‐Travis, A. (2009)

Применение реакции азосочетания в синтезе конъюгатов линейных полиэтиленгликолей с интерфероном α-2b и исследование их фармакологических свойств

Sheremet’ev, S. V., Лоншаков, Д. В., Korovkin, S. A., Белослудцева, Е. М., Катлинский, А. В., Semchenko, A. V., & Борисова, О. В. (2016) · Химико-фармацевтический журнал · doi:10.30906/0023-1134-2016-50-12-16-21

Rational and Combinatorial Methods to Create Designer Protein Interfaces

Lui, B. H., & Cochran, J. R. (2011) · Comprehensive Biomaterials · doi:10.1016/b978-0-08-055294-1.00258-0

Funcionalização do polietilenoglicol metil éter via reação de bromoacetilação: ativação, caracterização por MALDI-TOF e mecanismo de reação

Cordeiro, L. P. B., Lima, W. G., Soares, A. C., Borges, M. H., de Lima, M. E., & Brito, J. C. M. (2020) · Revista Colombiana de Ciencias Químico Farmacéuticas · doi:10.15446/rcciquifa.v49n3.91249

Introduction

Uchegbu, I. F. (2013) · Springer eBooks · doi:10.1007/978-1-4614-9164-4_1

PEGylation

Zydney, A. L. (2015) · Springer eBooks · doi:10.1007/978-3-642-40872-4_441-4

Specificity in protein chemistry and analysis

Liu, S. (2017) · Digital Repository Service (Northeastern University) · doi:10.17760/d20253330

Faculty Opinions recommendation of Chemoenzymatic reversible immobilization and labeling of proteins without prior purification.

Chalker, J. M. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.716597816.792002817

Polyethylene glycol

Malafaia, G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-824315-2.00985-4

The Usage of PEG in Drug Delivery Systems- A Mini Review

Yenilmez, E. (2022) · Polymer Science Peer Review Journal · doi:10.31031/psprj.2022.03.000566

Introduction

Uchegbu, I. F. (2024) · Springer eBooks · doi:10.1007/978-3-031-59478-6_1

Development of Technology for the Preparation of Pegylated Filgrastim and Studies of its Physicochemical and Biological Properties

Лоншаков, Д. В., Sheremet’ev, S. V., Бобрышева, И. В., Grebennikova, O. A., Хурсевич, Е. М., & Korovkin, S. A. (2024) · Pharmaceutical Chemistry Journal · doi:10.1007/s11094-024-03253-4

Supramolecular polymerization of poly(2-ethyl-2-oxazoline) functionalized ureido-pyrimidinone monomers

Bellan, R., Purino, M. A., Loman, T., van Genderen, M. H. P., Hoogenboom, R., & Dankers, P. Y. W. (2025) · European Polymer Journal · doi:10.1016/j.eurpolymj.2025.114134

Development of a fit-for-purpose semi-homogeneous competitive ELISA for total PEG quantitation in a PEGylated molecule

Yu, N., Chang, V., Nijem, I., & Liu, Y. (2025) · Bioanalysis · doi:10.1080/17576180.2025.2580287

PEGylation

Zydney, A. L. (2016) · Springer eBooks · doi:10.1007/978-3-662-44324-8_441

PEGylation of Proteins as Tailored Chemistry for Optimized Bioconjugates

Pasut, G., & Veronese, F. M. (2005) · Advances in polymer science · doi:10.1007/12_022 · Cited by 93

Peptide and protein PEGylation III: advances in chemistry and clinical applications

Veronese, F. M., & Harris, J. M. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.08.003 · Cited by 86

PEGylation: An Approach for Drug Delivery. A Review

Jain, A., & Jain, S. (2008) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v25.i5.10 · Cited by 185

PROTE INAS PEGILADAS: PRODUCCI ON, PURIFICACI ON Y APLICACIONES PEGYLATED PROTEINS: PRODUCTION, PURIFICATION, AND APPLICATIONS

Mayolo‐Deloisa, K., & Rito‐Palomares, M. (2010)

PROGRESS RESEARCH OF IN PEG MODIFIED DRUGS

Sha, R. (2007)