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PEGylated Protein Drugs: Basic Science and Clinical Applications
Abstract
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such
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“Low molecular weight PEG and PEG-conjugates of 20 kDa or less, have a low incidence of toxicity [66–68].”
From Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval. (2020) · cites this paper as [68]
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“Polyethyleneglycol (PEG) (also known as poly(ethylene oxide) (PEO)) has been the most frequently employed hydrophilic, shell-forming block in polymeric micelles thus far due to its safety profile in humans and classification as “Generally Regarded as Safe” (GRAS) by the US Food and Drug Administration (USFDA).”
From Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval. (2020) · cites this paper as [68]
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Metadata
- Authors
- Veronese, F. M.
- Affiliations
- University of Padua (IT)
- Corresponding author
- Francesco Maria Veronese
- Venue
- Birkhäuser Basel eBooks
- Publisher
- Birkhäuser Basel
- Published
- 2009
- OpenAlex
- W618357767
- Cited by
- 241
- References
- 0
- Citations by year
- 2025: 8 · 2024: 7 · 2023: 14 · 2022: 13 · 2021: 19 · 2020: 19 · 2019: 16 · 2018: 17 · 2017: 13 · 2016: 15 · 2015: 16 · 2014: 23 · 2013: 22 · 2012: 21
- FWCI
- 2.22
- Type
- book
- Language
- en
- Open access
- closed
- Licence
- Locations
- Birkhäuser Basel eBooks (publishedVersion)
- DIAL (Catholic University of Leuven) (submittedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Drug Solubulity and Delivery Systems
- Keywords
- PEGylation, polyethylene glycol, PEG conjugates, protein drugs, drug modification, pharmacokinetics, drug delivery, clinical application
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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