Cited by 41Aldose Reductase and TaurineNeurogenesis and neuroplasticity mechanismsNeonatal and fetal brain pathology

Functions of Maternally-Derived Taurine in Fetal and Neonatal Brain Development

Tochitani, Shiro·2017·Advances in experimental medicine and biology

Abstract

Taurine (2-aminoethanesulfonic acid) is a sulfur-containing organic acid, which has various physiological functions, including membrane stabilization, cell-volume regulation, mitochondrial protein translocation, anti-oxidative activity, neuroprotection against neurotoxicity and modulation of intracellular calcium levels. Taurine also activates GABA A receptors and glycine receptors. Mammalian fetuses and infants are dependent on taurine delivered from their mothers via either the placenta or their mother's milk. Taurine is a molecule that links mother-fetus or mother-infant bonding.This review describes the functions of taurine and the mechanisms of action of taurine in fetal and brain development. Taurine is involved in regulating the proliferation of neural progenitors, migration of newly-generated neurons, and the synapse formation of neurons after migration during fetal and neonatal development. In this review, we also discuss the environmental factors that might influence the functional roles of taurine in neural development.

Integrity signals

Registry

Crossref · 10.1007/978-94-024-1079-2_2

Cites

53 of 53 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Taurine is essential for brain development and can be produced by neurons and astrocytes or transported through the blood-brain-barrier via TauT.

    “Taurine is essential for brain development (Kilb and Fukuda, 2017; Tochitani, 2017) and can be produced by neurons and astrocytes (Vitvitsky et al., 2011) or transported through the blood-brain-barrier via the Taurine transporter TauT (Benrabh et al., 1995).”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Tochitani, S.
Affiliations
Kanazawa University (JP)
Corresponding author
Tochitani, Shiro
Venue
Advances in experimental medicine and biology
Published
2017
Volume
975 Pt 1
Pages
17-25
ISSN
  • 0065-2598 (ISSN-L)
  • 2214-8019
OpenAlex
W2749095096
Cited by
41
References
53
Citations by year
2026: 4 · 2025: 3 · 2024: 3 · 2023: 5 · 2022: 10 · 2021: 6 · 2020: 2 · 2019: 7 · 2018: 1
FWCI
4.17
Type
book chapter
Language
en
Open access
closed
Locations
  • Advances in experimental medicine and biology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Aldose Reductase and Taurine
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal and fetal brain pathology
Keywords
taurine, fetal brain development, neonatal brain development, placental transfer, breast milk, neural progenitor proliferation, neuronal migration, synaptogenesis, neuroprotection, GABA-A receptor modulation, maternal-fetal bonding
MeSH terms
Animals, Brain, Female, Fetus, Humans, Maternal-Fetal Exchange, Pregnancy, Taurine, Neurogenesis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review