Interactions between two antagonistic reflexes in the nematode Caenorhabditis elegans
Abstract
1. Antagonistic reflexes that use the same final common path cannot be activated simultaneously; as a consequence one reflex often inhibits the expression of the other. Results of experiments with two antagonistic reflexes in Caenorhabditis elegans showed that the reflex inhibition in this simple animal is the same as in more complex organisms. Thus C. elegans can serve as a model system for studying the neural mechanisms underlying these behavioral patterns. 2. In adult C. elegans tail-touch normally elicits forward movement, while tap normally elicits backward movement. When tail-touch is delivered 1 s before a tap, reversals to the tap are inhibited and the magnitude of any reversal that does occur is reduced. 3. The relative magnitude of the 2 stimuli, tail-touch and tap, affects the amount of inhibition observed. 4. The effectiveness of tail-touch as an inhibitory stimulus can be varied as a result of experience. Habituating the response to tail-touch decreased the inhibition of reversal to tap following a tail-touch. 4. The tail-touch induced inhibition of reversal to tap diminishes over an interval of at least 10 s; however, following the inhibition an enhancement of responding to tap is seen. 6. Inhibition of reversal to tap is present in worms of all stages of development including newly hatched worms.
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The C. elegans avoidance response consists of two main reflexes: forward and backward progression.
“Its avoidance response consists of two main reflexes: forward and backward progression7.”
From Corollary discharge across the animal kingdom (2008) · cites this paper as [7]
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Self-citation
- Authors
- Rankin, C.
- Venue
- Journal of Comparative Physiology A
- Published
- 1991-07
- Volume
- 169
- Issue
- 1
- Pages
- 59-67
- ISSN
- 0340-7594 (ISSN-L)
- 1432-1351
- OpenAlex
- W2035424459
- Cited by
- 38
- References
- 22
- Citations by year
- 2024: 1 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 1 · 2014: 3
- FWCI
- 0.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Comparative Physiology A (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- reflex inhibition, Caenorhabditis elegans, reversal behavior, final common pathway, habituation, stimulus intensity, developmental stages
- MeSH terms
- Animals, Behavior, Animal, Caenorhabditis, Habituation, Psychophysiologic, Physical Stimulation, Reflex
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