Cited by 549

The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.

Quantitative aspects of reactive gliosis: A review

Norton, W. T., Aquino, D. A., Hozumi, I., Chiu, F. -C., Brosnan, C. F.·1992·Neurochemical Research

DOI 10.1007/bf00993263

Open this paper in CoChat — free account

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1007/bf00993263

Cites

74 of 74 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence
Bignami, A., Eng, L. F., Dahl, D., & Uyeda, C. T. (1972) · Brain Research · doi:10.1016/0006-8993(72)90398-8 · Cited by 1,455
An acidic protein isolated from fibrous astrocytes
Eng, L. F., Vanderhaeghen, J. J., Bignami, A., & Gerstl, B. (1971) · Brain Research · doi:10.1016/0006-8993(71)90668-8 · Cited by 1,230
Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury
Giulian, D., & Lachman, L. B. (1985) · Science · doi:10.1126/science.3872478 · Cited by 855
Glial fibrillary acidic protein (GFAP): the major protein of glial intermediate filaments in differentiated astrocytes
Eng, L. F. (1985) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(85)80063-1 · Cited by 734
Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system
Schnitzer, J., Franke, W., & Schachner, M. (1981) · The Journal of Cell Biology · doi:10.1083/jcb.90.2.435 · Cited by 637
Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization
Giulian, D., Woodward, J., Young, D., Krebs, J., & Lachman, L. (1988) · The Journal of Neuroscience · doi:10.1523/jneurosci.08-07-02485.1988 · Cited by 588
Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.
Selmaj, K. W., Farooq, M., Norton, W. T., Raine, C. S., & Brosnan, C. F. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.144.1.129 · Cited by 544
Self-citation
Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin
Pixley, S. K. R., & de Vellis, J. (1984) · Developmental Brain Research · doi:10.1016/0165-3806(84)90097-x · Cited by 533
Astroglia in CNS injury
Hatten, M. E., Liem, R. K. H., Shelanski, M. L., & Mason, C. A. (1991) · Glia · doi:10.1002/glia.440040215 · Cited by 498
The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain
Giulian, D., Chen, J., Ingeman, J., George, J., & Noponen, M. (1989) · The Journal of Neuroscience · doi:10.1523/jneurosci.09-12-04416.1989 · Cited by 498
Adrenoleukodystrophy: A Clinical and Pathological Study of 17 Cases
Schaumburg, H. H. (1975) · Archives of Neurology · doi:10.1001/archneur.1975.00490510033001 · Cited by 475
THE ASTROGLIAL RESPONSE TO STABBING. IMMUNOFLUORESCENCE STUDIES WITH ANTIBODIES TO ASTROCYTE‐SPECIFIC PROTEIN (GFA) IN MAMMALIAN AND SUBMAMMALIAN VERTEBRATES
BIGNAMI, A., & DAHL, D. (1976) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1976.tb00488.x · Cited by 474
Antibodies to neurofilament, glial filament, and fibroblast intermediate filament proteins bind to different cell types of the nervous system.
Yen, S. H., & Fields, K. L. (1981) · The Journal of cell biology · doi:10.1083/jcb.88.1.115 · Cited by 405
Fibrillary astrocytes proliferate in response to brain injury
Latov, N., Nilaver, G., Zimmerman, E. A., Johnson, W. G., Silverman, A.-J., Defendini, R., & Cote, L. (1979) · Developmental Biology · doi:10.1016/0012-1606(79)90127-1 · Cited by 397
Observations on the astrocyte response to a cerebral stab wound in adult rats
Mathewson, A. J., & Berry, M. (1985) · Brain Research · doi:10.1016/0006-8993(85)91499-4 · Cited by 353
The Two Patterns of Reactive Astrocytosis in Postischemic Rat Brain
Petito, C. K., Morgello, S., Felix, J. C., & Lesser, M. L. (1990) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1990.141 · Cited by 337
Immunohistochemical studies on the proliferation of reactive astrocytes and the expression of cytoskeletal proteins following brain injury in rats
Takamiya, Y., Kohsaka, S., Toya, S., Otani, M., & Tsukada, Y. (1988) · Developmental Brain Research · doi:10.1016/0165-3806(88)90045-4 · Cited by 277
The proliferation of astrocytes around a needle wound in the rat brain.
Jb, C. (1970) · PubMed Central · Cited by 272
The vimentin‐GFA protein transition in rat neuroglia cytoskeleton occurs at the time of myelination
Dahl, D. (1981) · Journal of Neuroscience Research · doi:10.1002/jnr.490060608 · Cited by 266
Quantitative changes in the synaptic vesicle proteins synapsin I and p38 and the astrocyte-specific protein glial fibrillary acidic protein are associated with chemical-induced injury to the rat central nervous system
Brock, T., & O'Callaghan, J. (1987) · The Journal of Neuroscience · doi:10.1523/jneurosci.07-04-00931.1987 · Cited by 245
Progressive Accumulation of Toxic Metabolite in a Genetic Leukodystrophy
Igisu, H., & Suzuki, K. (1984) · Science · doi:10.1126/science.6719111 · Cited by 236
Glial fibrillary acidic protein and vimentin in the experimental glial reaction of the rat brain
Schiffer, D., Giordana, M. T., Migheli, A., Giaccone, G., Pezzotta, S., & Mauro, A. (1986) · Brain Research · doi:10.1016/0006-8993(86)90399-9 · Cited by 225
Brain injury induces c-fos protein(s) in nerve and glial-like cells in adult mammalian brain
Dragunow, M., & Robertson, H. A. (1988) · Brain Research · doi:10.1016/0006-8993(88)90088-1 · Cited by 222
Development of cerebellar astroglia: Transitions in form and cytoskeletal content
Bovolenta, P., Liem, R. K. H., & Mason, C. A. (1984) · Developmental Biology · doi:10.1016/0012-1606(84)90189-1 · Cited by 200
Hormones and growth factors induce the synthesis of glial fibrillary acidic protein in rat brain astrocytes
Morrison, R. S., De Vellis, J., Lee, Y. L., Bradshaw, R. A., & Eng, L. F. (1985) · Journal of Neuroscience Research · doi:10.1002/jnr.490140202 · Cited by 196
GD3 ganglioside is a glycolipid characteristic of immature neuroectodermal cells
Goldman, J. E., Hirano, M., Yu, R. K., & Seyfried, T. N. (1984) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(84)80017-x · Cited by 191
Induction of a heat shock gene at the site of tissue injury in the rat brain
Brown, I. R., Rush, S., & Ivy, G. O. (1989) · Neuron · doi:10.1016/0896-6273(89)90044-5 · Cited by 181
Quantitative studies on proliferative changes of reactive astrocytes in mouse cerebral cortex
Miyake, T., Hattori, T., Fukuda, M., Kitamura, T., & Fujita, S. (1988) · Brain Research · doi:10.1016/0006-8993(88)90757-3 · Cited by 168
Glial fibrillary acidic protein in cryogenic lesions of the rat brain
Amaducci, L. A., Forno, K. I., & Eng, L. F. (1981) · Neuroscience Letters · doi:10.1016/0304-3940(81)90052-5 · Cited by 150
REACTIVE GLIOSIS
Lindsay, R. M. (1986) · Elsevier eBooks · doi:10.1016/b978-0-12-250453-2.50013-x · Cited by 150
Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
O'Callaghan, J. P., Miller, D. B., & Reinhard, J. F. (1990) · Brain Research · doi:10.1016/0006-8993(90)91526-m · Cited by 145
Fungal Aneurysms of Intracranial Vessels
HORTEN, B. C., Abbott, G. F., & Porro, R. S. (1976) · Archives of Neurology · doi:10.1001/archneur.1976.00500080055008 · Cited by 143
Messenger RNA for glial fibrillary acidic protein is decreased in rat brain following acute and chronic corticosterone treatment
Nichols, N. R., Osterburg, H. H., Masters, J. N., Millar, S. L., & Finch, C. E. (1990) · Molecular Brain Research · doi:10.1016/0169-328x(90)90066-m · Cited by 137
Isolation and characterization of glial filaments from human brain.
Goldman, J. E., Schaumburg, H. H., & Norton, W. T. (1978) · The Journal of Cell Biology · doi:10.1083/jcb.78.2.426 · Cited by 137
Self-citation
The Reactive Astrocyte
Nathaniel, E. J. H., & Nathaniel, D. R. (1981) · Advances in cellular neurobiology · doi:10.1016/b978-0-12-008302-2.50012-2 · Cited by 136
Filament proteins in rat optic nerves undergoing Wallerian degeneration: Localization of vimentin, the fibroblastic 100-Å filament protein, in normal and reactive astrocytes
Dahl, D. R., Bignami, A., Weber, K. K., & Osborn, M. (1981) · Experimental Neurology · doi:10.1016/0014-4886(81)90283-1 · Cited by 136
Differentiation of astrocytes and oligodendrocytes from germinal matrix cells in primary culture
Goldman, J., Geier, S. S., & Hirano, M. (1986) · Journal of Neuroscience · doi:10.1523/jneurosci.06-01-00052.1986 · Cited by 135
Immunocytochemical staining for glial fibrillary acidic protein and the metabolism of cytoskeletal proteins in experimental allergic encephalomyelitis
Smith, M. E., Somera, F. P., & Eng, L. F. (1983) · Brain Research · doi:10.1016/0006-8993(83)90822-3 · Cited by 129
Biochemical and immunocytochemical changes in glial fibrillary acidic protein after sab wounds
Hozumi, I., Chiu, F., & Norton, W. T. (1990) · Brain Research · doi:10.1016/0006-8993(90)90492-t · Cited by 126
Self-citation
Human astrocytes proliferate in response to tumor necrosis factor alpha
Barna, B. P., Estes, M. L., Jacobs, B., Hudson, S., & Ransohoff, R. M. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90108-y · Cited by 123
Trauma‐induced proliferation of astrocytes in the brains of young and aged rats
Topp, K. S., Faddis, B. T., & Vijayan, V. K. (1989) · Glia · doi:10.1002/glia.440020309 · Cited by 113
Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase C‐dependent mechanisms
Shafit‐Zagardo, B., Kume-Iwaki, A., & Goldman, J. E. (1988) · Glia · doi:10.1002/glia.440010507 · Cited by 112
Reaction of oligodendrocytes and astrocytes to trauma and implantation. A combined autoradiographic and immunohistochemical study.
Ludwin, S. K. (1985) · PubMed · Cited by 111
MULTIPLE SCLEROSIS: PATHOLOGY, DIAGNOSIS AND MANAGEMENT
Hammond, S. R. (1984) · Australian and New Zealand Journal of Medicine · doi:10.1111/j.1445-5994.1984.tb03593.x · Cited by 110
GANGLIOSIDE ABNORMALITIES IN MULTIPLE SCLEROSIS
Yu, R. K., Ledeen, R. W., & Eng, L. F. (1974) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1974.tb06931.x · Cited by 92
Glucocorticoids regulate the concentration of glial fibrillary acidic protein throughout the brain
O'Callaghan, J. P., Brinton, R. D., & McEwen, B. S. (1989) · Brain Research · doi:10.1016/0006-8993(89)90156-x · Cited by 90
Glial fibrillary acidic protein messenger RNA and glutamine synthetase activity after nervous system injury
Condorelli, D. F., Dell’Albani, P., Kaczmarek, L., Messina, L., Spampinato, G., Avola, R., Messina, A., & Stella, A. M. G. (1990) · Journal of Neuroscience Research · doi:10.1002/jnr.490260216 · Cited by 89
Glial Fibrillary Acidic Protein Increases in the Spinal Cord of Lewis Rats with Acute Experimental Autoimmune Encephalomyelitis
Aquino, D. A., Chiu, F., Brosnan, C. F., & Norton, W. T. (1988) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1988.tb03072.x · Cited by 89
Self-citation
Expression of microtubule-associated protein 2 by reactive astrocytes.
Geisert, E. E., Johnson, H. G., & Binder, L. I. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.10.3967 · Cited by 86
Tumor Necrosis Factor‐Induced Proliferation of Astrocytes from Mature Brain Is Associated with Down‐Regulation of Glial Fibrillary Acidic Protein mRNA
Selmaj, K. W., Shafit‐Zagardo, B., Aquino, D. A., Farooq, M., Raine, C. S., Norton, W. T., & Brosnan, C. F. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb08225.x · Cited by 86
Self-citation
Regulation of glial fibrillary acidic protein (GFAP) expression in CNS development and in pathological states
Chiu, F., & Goldman, J. E. (1985) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(85)80067-9 · Cited by 83
Self-citation
Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat.
Brosnan, C. F., Goldmuntz, E. A., Cammer, W., Factor, S. M., Bloom, B. R., & Norton, W. T. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.17.5915 · Cited by 82
Self-citation
The proliferative response of astrocytes to injury in neonatal rat brain. A combined immunocytochemical and autoradiographic study
Janeczko, K. J. (1988) · Brain Research · doi:10.1016/0006-8993(88)90229-6 · Cited by 82
GFAP mRNA levels following stab wounds in rat brain
Hozumi, I., Aquino, D. A., & Norton, W. T. (1990) · Brain Research · doi:10.1016/0006-8993(90)90142-x · Cited by 72
Self-citation
Dissociation of GFAP intermediate filaments in eae: Observations in the lumbar spinal cord
Eng, L. F., D'Amelio, F. E., & Smith, M. E. (1989) · Glia · doi:10.1002/glia.440020504 · Cited by 72
Glial fibrillary acidic protein in chronic relapsing experimental allergic encephalomyelitis in SJL/J mice
Smith, M. E., & Eng, L. F. (1987) · Journal of Neuroscience Research · doi:10.1002/jnr.490180129 · Cited by 57
Prazosin treatment suppresses increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat.
Goldmuntz, E. A., Brosnan, C. F., & Norton, W. T. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.137.11.3444 · Cited by 56
Self-citation
Origin of contralateral reactive gliosis in surgically injured rat cerebral cortex
Moumdjian, R. A., Antel, J. P., & Yong, V. W. (1991) · Brain Research · doi:10.1016/0006-8993(91)90965-x · Cited by 53
Astrocytic reactivity and intermediate filament metabolism in experimental autoimmune encephalomyelitis: The effect of suppression with prazosin
Goldmuntz, E. A., Brosnan, C. F., Chiu, F., & Norton, W. T. (1986) · Brain Research · doi:10.1016/0006-8993(86)91365-x · Cited by 53
Self-citation
Cerebellar hypoplasia in the Gunn rat is associated with quantitative changes in neurotypic and gliotypic proteins.
O'Callaghan, J. P., & Miller, D. B. (1985) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)23451-6 · Cited by 53
Reactions of S-100-positive glia after injury of mouse cerebral cortex
Miyake, T., Hattori, T., Fukuda, M., et al. (1989) · Brain Research · doi:10.1016/0006-8993(89)90005-x · Cited by 51
Separate blood and brain origins of proliferating cells during gliosis in adult brains
Morshead, C. M., & van der Kooy, D. (1990) · Brain Research · doi:10.1016/0006-8993(90)91606-h · Cited by 50
Preferential histochemical staining of protoplasmic and fibrous astrocytes in rat CNS with GFAP antibodies using different fixatives
Shehab, S. A. S., Cronly-Dillon, J. R., Nona, S. N., & Stafford, C. A. (1990) · Brain Research · doi:10.1016/0006-8993(90)90996-o · Cited by 46
Immunocytochemical localization of GD3 ganglioside to astrocytes in murine cerebellar mutants
LeVine, S. M., Seyfried, T. N., Yu, R. K., & Goldman, J. E. (1986) · Brain Research · doi:10.1016/0006-8993(86)90420-8 · Cited by 46
Expression of Glial Fibrillary Acidic Protein and Neurofilament mRNA in Gliosis Induced by Experimental Autoimmune Encephalomyelitis
Aquino, D. A., Shafit‐Zagardo, B., Brosnan, C. F., & Norton, W. T. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb01975.x · Cited by 40
Self-citation
Expression of glial fibrillary acidic protein in the CNS and PNS of murine globoid cell leukodystrophy, the twitcher.
The University of North Carolina at Chapel Hill University Libraries (2020) · PubMed Central · doi:10.17615/t123-hm09 · Cited by 39
Modulation of GFAP mRNA levels following toxic lesions in the basal ganglia of the rat
Rataboul, P., Vernier, P., Biguet, N. F., Mallet, J. J., Poulat, P., & Privat, A. (1989) · Brain Research Bulletin · doi:10.1016/0361-9230(89)90140-8 · Cited by 37
Blood-Brain Barrier and DNA Changes During the Evolution of Experimental Allergic Encephalomyelitis
Oldendorf, W. H., & Towner, H. F. (1974) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197410000-00004 · Cited by 35
Rapid Increases in Glial Fibrillary Acidic Protein mRNA and Protein Levels in the Copper‐Deficient, Brindled Mouse
Shafit‐Zagardo, B., Peterson, C., & Goldman, J. E. (1988) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1988.tb03095.x · Cited by 24
Coexpression of glial fibrillary acidic protein and vimentin in the central and peripheral nervous systems of the twitcher mutant
Chiu, F., Sacchi, R., Cláudio, L., Kobayashi, S., & Suzuki, K. (1988) · Glia · doi:10.1002/glia.440010202 · Cited by 23
Self-citation
Gliosis in the spinal cords of rats with experimental allergic encephalomyelitis: Immunostaining of carbonic anhydrase and vimentin in reactive astrocytes
Cammer, W., Tansey, F. A., & Brosnan, C. F. (1989) · Glia · doi:10.1002/glia.440020403 · Cited by 23
Self-citation
In vitro studies on the characterization of cellular proliferation following neuronal injury in the adult rat brain
Katz, I. R., Iacovitti, L., & REIS, D. J. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90145-d · Cited by 12
Changes in the metabolism of glial fibrillary acid protein (GFAP) during chronic relapsing experimental allergic encephalomyelitis in the strain 13 guinea-pig
Linington, C., SUCKLING, A. J., Weir, M. R., & Cuzner, M. L. (1984) · Neurochemistry International · doi:10.1016/0197-0186(84)90083-4 · Cited by 11
ASTROCYTE MODIFICATIONS IN NEUROLOGICAL MUTATIONS OF THE MOUSE
Baumann, N., Jacque, C., & Dupouey, P. (1986) · Elsevier eBooks · doi:10.1016/b978-0-12-250453-2.50015-3 · Cited by 7

Astrocytes: Biology and pathology
Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
Rice, D., & Barone, S. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108s3511 · Cited by 2,944
Reactive astrocytes: cellular and molecular cues to biological function
Ridet, J. L., Privat, A., Malhotra, S. K., & Gage, F. H. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01139-9 · Cited by 1,766
Diffusion in Brain Extracellular Space
Syková, E., & Nicholson, C. (2008) · Physiological Reviews · doi:10.1152/physrev.00027.2007 · Cited by 1,481
Astrocyte barriers to neurotoxic inflammation
Sofroniew, M. V. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3898 · Cited by 1,202

See all 549

Authors: Norton, W. T., Aquino, D. A., Hozumi, I., Chiu, F. C., & Brosnan, C. F.
Venue: Neurochemical Research
Publisher: Springer Science and Business Media LLC
Published: 1992-09
Volume: 17
Issue: 9
Pages: 877-885
ISSN: 0364-3190 (ISSN-L)
1573-6903
DOI: 10.1007/bf00993263
OpenAlex: W1992559673
Cited by: 549
References: 74
FWCI: 17.98
Type: journal article
Language: en
Open access: closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

Quantitative aspects of reactive gliosis: A review

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks

Data sources