The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Bioactive compounds produced by cyanobacteria
Open accessAbstract
Cyanobacteria produce a large number of compounds with varying bioactivities. Prominent among these are toxins: hepatotoxins such as microcystins and nodularins and neurotoxins such as anatoxins and saxitoxins. Cytotoxicity to tumor cells has been demonstrated for other cyanobacterial products, including 9-deazaadenosine, dolastatin 13 and analogs. A number of compounds in cyanobacteria are inhibitors of proteases — micropeptins, cyanopeptolins, oscillapeptin, microviridin, aeruginosins- and other enzymes, while still other compounds have no recognized biological activities. In general cyclic peptides and depsipeptides are the most common structural types, but a wide variety of other types are also found: linear peptides, guanidines, phosphonates, purines and macrolides. The close similarity or identity in structures between cyanobacterial products and compounds isolated from sponges, tunicates and other marine invertebrates suggests the latter compounds may be derived from dietary or symbiotic blue-green algae.
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Cites
MacKintosh, C., Beattie, K. A., Klumpp, S., Cohen, P., & Codd, G. A. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)80245-e · Cited by 1,653
Cyanobacteria secondary metabolites—the cyanotoxins
Carmichael, W. W. (1992) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1992.tb01858.x · Cited by 1,457
Carmichael, W. W. (1994) · Scientific American · doi:10.1038/scientificamerican0194-78 · Cited by 1,096
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR
Nishiwaki-Matsushima, R., Ohta, T., Nishiwaki, S., Suganuma, M., Kohyama, K., Ishikawa, T., Carmichael, W. W., & Fujiki, H. (1992) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/bf01629424 · Cited by 806
Cylindrospermopsin: a potent hepatotoxin from the blue-green alga Cylindrospermopsis raciborskii
Ohtani, I., Moore, R. E., & Runnegar, M. T. C. (1992) · Journal of the American Chemical Society · doi:10.1021/ja00046a067 · Cited by 625
Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases.
Honkanen, R. E., Zwiller, J., Moore, R. E., Daily, S. L., Khatra, B. S., Dukelow, M., & Boynton, A. L. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)45384-1 · Cited by 588
Inhibition of protein phosphatases by microcystis and nodularin associated with hepatotoxicity
Yoshizawa, S., Matsushima, R., Watanabe, M. F., Harada, K.-I., Ichihara, A., Carmichael, W. W., & Fujiki, H. (1990) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/bf01637082 · Cited by 578
Nodularin, microcystin, and the configuration of Adda
Rinehart, K. L., Harada, K., Namikoshi, M., Chen, C., Harvis, C. A., Munro, M. H. G., Blunt, J. W., Mulligan, P. E., Beasley, V. R., & et al. (1988) · Journal of the American Chemical Society · doi:10.1021/ja00233a049 · Cited by 545
Self-citationStructure and biosynthesis of toxins from blue-green algae (cyanobacteria)
Rinehart, K. L., Namikoshi, M., & Choi, B. W. (1994) · Journal of Applied Phycology · doi:10.1007/bf02186070 · Cited by 515
Self-citationNaming of cyclic heptapeptide toxins of cyanobacteria (blue-green algae)
Carmichael, W. W., Beasley, V., Bunner, D. L., Eloff, J. N., Falconer, I., Gorham, P., Harada, K.-I., Krishnamurthy, T., Min-Juan, Y., Moore, R. E., et al. (1988) · Toxicon · doi:10.1016/0041-0101(88)90195-x · Cited by 363
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Cited by
Toxic Cyanobacteria in Water: A Guide to their Public Health Consequences, Monitoring and Management
(1999) · CRC Press eBooks · doi:10.1201/9781482295061 · Cited by 2,574
The rise of harmful cyanobacteria blooms: the potential roles of eutrophication and climate change
O’Neil, J. M., Davis, T. W., Burford, M. A., & Gobler, C. J. (2012) · Harmful Algae · doi:10.1016/j.hal.2011.10.027 · Cited by 2,225
Valuable Products from Biotechnology of Microalgae
Pulz, O., & Gross, W. (2004) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-004-1647-x · Cited by 2,132
Overview of microalgal extracellular polymeric substances (EPS) and their applications
Xiao, R., & Zheng, Y. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.08.004 · Cited by 938
Marine Polysaccharides from Algae with Potential Biomedical Applications
De Jesus Raposo, M., De Morais, A., & De Morais, R. (2015) · Marine Drugs · doi:10.3390/md13052967 · Cited by 686
Metadata
- Authors
- Namikoshi, M., & Rinehart, K.
- Venue
- Journal of Industrial Microbiology & Biotechnology
- Publisher
- Oxford University Press (OUP)
- Published
- 1996-11
- Volume
- 17
- Issue
- 5-6
- Pages
- 373-384
- ISSN
- 1367-5435 (ISSN-L)
- 0169-4146
- 1476-5535
- OpenAlex
- W2004745717
- Cited by
- 356
- References
- 72
- FWCI
- 4.20
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
