Open up the lung and keep the lung open

Ventilator-induced Lung Injury: Lessons from Experimental Studies

DREYFUSS, D., & SAUMON, G. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.1.9604014 · Cited by 2,297

Effect of Mechanical Ventilation on Inflammatory Mediators in Patients With Acute Respiratory Distress Syndrome: A Randomized Controlled Trial

Ranieri, V. M., Suter, P. M., Tortorella, C., De Tullio, R., Dayer, J. M., Brienza, A., Bruno, F., & Slutsky, A. S. (1999) · JAMA · doi:10.1001/jama.282.1.54 · Cited by 1,908

An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome

Fan, E., Del Sorbo, L., Goligher, E. C., Hodgson, C. L., Munshi, L., Walkey, A. J., Adhikari, N. K. J., Amato, M. B. P., Branson, R., Brower, R. G., et al. (2017) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201703-0548st · Cited by 1,630

Lung recruitment in patients with the acute respiratory distress syndrome.

Gattinoni, L., Caironi, P., Cressoni, M., Chiumello, D., Ranieri, V. M., Quintel, M., Russo, S., Patroniti, N., Cornejo, R., & Bugedo, G. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052052 · Cited by 1,548

Beneficial effects of the “open lung approach” with low distending pressures in acute respiratory distress syndrome. A prospective randomized study on mechanical ventilation.

Amato, M. B., Barbas, C. S., Medeiros, D. M., Schettino, G. D. P., Lorenzi Filho, G., Kairalla, R. A., Deheinzelin, D., Morais, C., Fernandes, E. D. O., & Takagaki, T. Y. (1995) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.152.6.8520744 · Cited by 625

Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients

Brower, R. G., Shanholtz, C. B., Fessler, H. E., Shade, D. M., White, P., Wiener, C. M., Teeter, J. G., Dodd-o, J. M., Almog, Y., & Piantadosi, S. (1999) · Critical Care Medicine · doi:10.1097/00003246-199908000-00015 · Cited by 575

Surfactant Therapy and Nasal Continuous Positive Airway Pressure for Newborns with Respiratory Distress Syndrome

Verder, H., Robertson, B., Greisen, G., Ebbesen, F., Albertsen, P., Lundstrom, K., & Jacobsen, T. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410203311603 · Cited by 448

Activation of human macrophages by mechanical ventilation in vitro

Pugin, J., Dunn, I., Jolliet, P., Tassaux, D., Magnenat, J.-L., Nicod, L. P., & Chevrolet, J.-C. (1998) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1998.275.6.l1040 · Cited by 352

Hyperventilation Induces Release of Cytokines from Perfused Mouse Lung

von BETHMANN, A. N., BRASCH, F., NÜSING, R., VOGT, K., VOLK, H. D., MÜLLER, K.-M., WENDEL, A., & UHLIG, S. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.1.9608052 · Cited by 340

Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial*

Kacmarek, R. M., Villar, J., Sulemanji, D., Montiel, R., Ferrando, C., Blanco, J., Koh, Y., Soler, J. A., Martínez, D., Hernández, M., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001383 · Cited by 288

Oxygenation Inhibits the Physiological Tissue-Protecting Mechanism and Thereby Exacerbates Acute Inflammatory Lung Injury

Thiel, M., Chouker, A., Ohta, A., Jackson, E., Caldwell, C., Smith, P., Lukashev, D., Bittmann, I., & Sitkovsky, M. V. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030174 · Cited by 287

Oxygenation Response to Positive End-Expiratory Pressure Predicts Mortality in Acute Respiratory Distress Syndrome. A Secondary Analysis of the LOVS and ExPress Trials

Goligher, E. C., Kavanagh, B. P., Rubenfeld, G. D., Adhikari, N. K. J., Pinto, R., Fan, E., Brochard, L. J., Granton, J. T., Mercat, A., Marie Richard, J.-C., et al. (2014) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201404-0688oc · Cited by 194

Ventilatory management of acute respiratory distress syndrome: A consensus of two.

Marini, J. J., & Gattinoni, L. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000104946.66723.a8 · Cited by 168

Personalizing mechanical ventilation according to physiologic parameters to stabilize alveoli and minimize ventilator induced lung injury (VILI)

Nieman, G. F., Satalin, J., Andrews, P., Aiash, H., Habashi, N. M., & Gatto, L. A. (2017) · Intensive Care Medicine Experimental · doi:10.1186/s40635-017-0121-x · Cited by 143