The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Pre‐operative radiotherapy prolongs survival in operable esophageal carcinoma: A randomized, multicenter study of pre‐operative radiotherapy and chemotherapy. The second scandinavian trial in esophageal cancer
Abstract
In a prospective multicenter study, 186 patients with squamous cell esophageal carcinoma, who after evaluation were considered suitable for surgery, were randomized to 4 treatment groups: Group 1, surgery alone; Group 2, pre‐operative chemotherapy (cisplatin and bleomycin) and surgery; Group 3, pre‐operative irradiation (35 Gy) and surgery; Group 4, pre‐operative chemotherapy, radiotherapy, and surgery. Three‐year survival was significantly higher in the pooled groups receiving radiotherapy as compared with the pooled groups not receiving radiotherapy. Comparison of the groups having pre‐operative chemotherapy with those not having chemotherapy showed no significant difference in survival. Female patients had a significantly better survival than males. The results indicate that pre‐operative irradiation had a beneficial effect on intermediate term survival, whereas the chemotherapy regime used did not influence survival.
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Cites
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Cited by
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Esophageal and Esophagogastric Junction Cancers
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Metadata
- Authors
- Nygaard, K., Hagen, S., Hansen, H. S., Hatlevoll, R., Hultborn, R., Jakobsen, A., Mäntyla, M., Modig, H., Munck‐Wikland, E., Rosengren, B., Tausjø, J., & Elgen, K.
- Venue
- World Journal of Surgery
- Publisher
- Wiley
- Published
- 1992-11
- Volume
- 16
- Issue
- 6
- Pages
- 1104-1109
- ISSN
- 0364-2313 (ISSN-L)
- 1432-2323
- OpenAlex
- W2029081428
- Cited by
- 615
- References
- 9
- FWCI
- 6.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Pre‐operative radiotherapy prolongs survival in operable esophageal carcinoma: A randomized, multicenter study of pre‐operative radiotherapy and chemotherapy. The second scandinavian trial in esophageal cancer. https://app.cochat.ai/papers/10.1007/bf02067069
- The paper
- Nygaard, K., Hagen, S., Hansen, H. S., Hatlevoll, R., Hultborn, R., Jakobsen, A., Mäntyla, M., Modig, H., Munck‐Wikland, E., Rosengren, B., Tausjø, J., & Elgen, K. (1992). Pre‐operative radiotherapy prolongs survival in operable esophageal carcinoma: A randomized, multicenter study of pre‐operative radiotherapy and chemotherapy. The second scandinavian trial in esophageal cancer. World Journal of Surgery. https://doi.org/10.1007/bf02067069
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
