The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Drug discovery from natural sources
Open accessAbstract
Organic compounds from terrestrial and marine organisms have extensive past and present use in the treatment of many diseases and serve as compounds of interest both in their natural form and as templates for synthetic modification. Over 20 new drugs launched on the market between 2000 and 2005, originating from terrestrial plants, terrestrial microorganisms, marine organisms, and terrestrial vertebrates and invertebrates, are described. These approved substances, representative of very wide chemical diversity, together with several other natural products or their analogs undergoing clinical trials, continue to demonstrate the importance of compounds from natural sources in modern drug discovery efforts.
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Citations
Cites
Natural products as sources of new drugs over the period 1981–2002
Newman, D. J., Cragg, G. M., & Snader, K. M. (2003) · Journal of Natural Products · doi:10.1021/np030096l · Cited by 3,082
The role of natural product chemistry in drug discovery
Butler, M. S. (2004) · Journal of Natural Products · doi:10.1021/np040106y · Cited by 1,381
The influence of natural products upon drug discovery (Antiquity to late 1999)
Newman, D. J., Cragg, G. M., & Snader, K. M. (2000) · Natural Product Reports · doi:10.1039/a902202c · Cited by 1,293
Hall, M. G., Wilks, M. F., Provan, W. M., Eksborg, S., & Lumholtz, B. (2001) · British Journal of Clinical Pharmacology · doi:10.1046/j.0306-5251.2001.01421.x · Cited by 110
Cited by
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,866
Plant-Derived Natural Products: A Source for Drug Discovery and Development
Chaachouay, N., & Zidane, L. (2024) · Drugs and Drug Candidates · doi:10.3390/ddc3010011 · Cited by 1,081
Blunt, J. W., Copp, B. R., Hu, W.-P., Munro, M. H. G., Northcote, P. T., & Prinsep, M. R. (2008) · Natural Product Reports · doi:10.1039/b701534h · Cited by 365
Leal, M. C., Puga, J., Serôdio, J., Gomes, N. C. M., & Calado, R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030580 · Cited by 294
Protective effect of porphyra-334 on UVA-induced photoaging in human skin fibroblasts
RYU, J., PARK, S.-J., KIM, I.-H., CHOI, Y. H., & NAM, T.-J. (2014) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2014.1815 · Cited by 172
Metadata
- Authors
- Chin, Y.-W., Balunas, M. J., Chai, H. B., & Kinghorn, A. D.
- Venue
- The AAPS Journal
- Published
- 2006-06
- Volume
- 8
- Issue
- 2
- Pages
- E239-E253
- ISSN
- 1550-7416 (ISSN-L)
- OpenAlex
- W2073476932
- Cited by
- 662
- References
- 4
- FWCI
- 7.74
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Drug discovery from natural sources. https://app.cochat.ai/papers/10.1007/bf02854894
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- Chin, Y.-W., Balunas, M. J., Chai, H. B., & Kinghorn, A. D. (2006). Drug discovery from natural sources. The AAPS Journal. https://doi.org/10.1007/bf02854894
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
