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Cited by 22Gastrointestinal motility and disordersClostridium difficile and Clostridium perfringens researchGut microbiota and health

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Clostridium difficile-related postinfectious IBS: a case of enteroglial microbiological stalking and/or the solution of a conundrum?

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Bassotti, Gabrio, Macchioni, Lara, Corazzi, Lanfranco, Marconi, Pierfrancesco, Fettucciari, Katia·2018·Cellular and Molecular Life Sciences
DOI 10.1007/s00018-017-2736-1PMC PMC11105427
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Abstract

Post-infectious irritable bowel syndrome is a well-defined pathological entity that develops in about one-third of subjects after an acute infection (bacterial, viral) or parasitic infestation. Only recently it has been documented that an high incidence of post-infectious irritable bowel syndrome occurs after Clostridium difficile infection. However, until now it is not known why in some patients recovered from this infection the gastrointestinal disturbances persist for months or years. Based on our in vitro studies on enteric glial cells exposed to the effects of C. difficile toxin B, we hypothesize that persistence of symptoms up to the development of irritable bowel syndrome might be due to a disturbance/impairment of the correct functions of the enteroglial intestinal network.

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  • Various Clostridium cluster species are associated with inflammatory bowel syndrome, metabolic disorders, and psychiatric conditions.

    “However, various Clostridium cluster species have been shown to be associated with inflammatory bowel syndrome (Bassotti et al., 2018), metabolic disorders (Woting and Blaut, 2016) and psychiatric conditions (Li et al., 2017b).”

    From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Bassotti et al., 2018

    The Introduction reports an association between *Clostridium difficile* infection and subsequent postinfectious irritable bowel syndrome (page unavailable in our copy). It does not establish that various Clostridium cluster species are associated with the condition, and the citing sentence calls it “inflammatory” rather than “irritable” bowel syndrome. The metabolic and psychiatric associations have separate citations and are not attributed to this paper. (LLM, conf=0.88)

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Research works printed but not linked: 51

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Metadata

Authors
Bassotti, G., Macchioni, L., Corazzi, L., Marconi, P., & Fettucciari, K.
Affiliations
University of Perugia (IT)
Corresponding author
Bassotti, Gabrio
ORCID
Venue
Cellular and Molecular Life Sciences
Publisher
Springer Science and Business Media LLC
Published
2017-12-28
Volume
75
Issue
7
Pages
1145-1149
ISSN
  • 1420-682X (ISSN-L)
  • 1420-9071
DOI
10.1007/s00018-017-2736-1
PMC
PMC11105427
OpenAlex
W2776242107
Cited by
22
References
5
Citations by year
2024: 2 · 2023: 5 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 3
FWCI
2.59
Type
journal article
Language
en
Open access
Licence
www.springer.com/tdm (unspecified)
Locations
  • Cellular and Molecular Life Sciences (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • INFM-OAR (INFN Catania) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Infectious Diseases › Clostridium difficile and Clostridium perfringens research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
post-infectious irritable bowel syndrome, Clostridium difficile infection, enteric glial cells, Clostridium difficile toxin B, persistent gastrointestinal symptoms, gut-brain axis
MeSH terms
Bacterial Proteins, Bacterial Toxins, Clostridium Infections, Humans, Intestinal Mucosa, Models, Theoretical, Neuroglia, Risk Factors, Clostridioides difficile, Enteric Nervous System, Irritable Bowel Syndrome, Host-Pathogen Interactions

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