The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Implication of gut microbiota metabolites in cardiovascular and metabolic diseases
Open accessAbstract
Evidence from the literature keeps highlighting the impact of mutualistic bacterial communities of the gut microbiota on human health. The gut microbita is a complex ecosystem of symbiotic bacteria which contributes to mammalian host biology by processing, otherwise, indigestible nutrients, supplying essential metabolites, and contributing to modulate its immune system. Advances in sequencing technologies have enabled structural analysis of the human gut microbiota and allowed detection of changes in gut bacterial composition in several common diseases, including cardiometabolic disorders. Biological signals sent by the gut microbiota to the host, including microbial metabolites and pro-inflammatory molecules, mediate microbiome–host genome cross-talk. This rapidly expanding line of research can identify disease-causing and disease-predictive microbial metabolite biomarkers, which can be translated into novel biodiagnostic tests, dietary supplements, and nutritional interventions for personalized therapeutic developments in common diseases. Here, we review results from the most significant studies dealing with the association of products from the gut microbial metabolism with cardiometabolic disorders. We underline the importance of these postbiotic biomarkers in the diagnosis and treatment of human disorders.
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Cites
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Host-gut microbiota metabolic interactions
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Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
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Cited by
Western Diet and the Immune System: An Inflammatory Connection
Christ, A., Lauterbach, M., & Latz, E. (2019) · Immunity · doi:10.1016/j.immuni.2019.09.020 · Cited by 907
Curcumin, Quercetin, Catechins and Metabolic Diseases: The Role of Gut Microbiota
Shabbir, U., Rubab, M., Daliri, E. B.-M., Chelliah, R., Javed, A., & Oh, D.-H. (2021) · Nutrients · doi:10.3390/nu13010206 · Cited by 334
Hatton‐Jones, K. M., du Toit, E. F., & Cox, A. J. (2022) · Neurogastroenterology & Motility · doi:10.1111/nmo.14300 · Cited by 5
Metadata
- Authors
- Brial, F., Le Lay, A., Dumas, M.-E., & Gauguier, D.
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2018-08-12
- Volume
- 75
- Issue
- 21
- Pages
- 3977-3990
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- OpenAlex
- W2885374389
- Cited by
- 198
- References
- 53
- FWCI
- 7.30
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Brial, F., Le Lay, A., Dumas, M.-E., & Gauguier, D. (2018). Implication of gut microbiota metabolites in cardiovascular and metabolic diseases. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-018-2901-1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
