Die aktualisierte S3-Leitlinie Schizophrenie: Entwicklungsprozess und ausgewählte Empfehlungen
Abstract
Schizophrenia is one of the most severe mental diseases and leads to significant personal and social impairments for affected persons. The illness is characterized by frequent relapses, results in increased mortality and is associated with the highest socioeconomic costs of all diseases. Moreover, patients with schizophrenia are often stigmatized in everyday life and also in most treatment settings. In 1998 the first German schizophrenia guidelines were published, followed by the first S3 guidelines for schizophrenia in 2006. The revision process started in 2012 coordinated by the German Association for Psychiatry, Psychotherapy and Psychosomatics (DGPPN) and the revised guidelines were published in 2019. The target group for the revised S3 guidelines includes all persons involved in the care of patients with schizophrenia in all sectors of the German healthcare system, including decision makers and insurance funds. Starting with an introduction of the biological, clinical and epidemiological basis of the disorder, recommendations for the diagnostics of schizophrenia, the detection of comorbidities, the use of antipsychotic medication and other somatic procedures, for psychotherapy, psychosocial interventions, handling of special treatment conditions and rehabilitation are made. Finally, recommendations for an evidence-based and optimal coordination within the healthcare system are made, followed by a discussion of the cost-effectiveness of treatment and presentation of strat…
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Guidelines recommend combination of psychological and pharmacological treatments for SSD along with physical exercise.
“International (NICE) and German national (S3) guidelines recommend a combination of psychological and pharmacological treatments for SSD along with physical exercise.2,7,8”
The control condition encompassed a multifaceted treatment in line with current national treatment guidelines within a real-world inpatient setting at a university hospital.
“Additionally, the control condition encompassed a multifaceted treatment in line with current national treatment guidelines2,26 within a real-world inpatient setting at a university hospital.”
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(2019) · doi:10.1007/978-3-662-59380-6 · Cited by 91 · see citing works
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Schulze, T., Hahn, E., Hahne, I., Bergmann, N., Fuchs, L. M., Mähler, F., Zierhut, M. M., Ta, T. M. T., Pijnenborg, G. H. M., & Böge, K. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.715670 · Cited by 17 · see citing works
Töbelmann, L., Hahne, I., Schulze, T., Bergmann, N., Fuchs, L., Zierhut, M., Hahn, E., & Böge, K. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1086468 · Cited by 13 · see citing works
Fischer, R., Scheunemann, J., Bohlender, A., Duletzki, P., Nagel, M., & Moritz, S. (2022) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2755 · Cited by 6 · see citing works
Hahne, I., Zierhut, M., Bergmann, N., Hahn, E., Ta, T. M. T., Calvano, C., Bajbouj, M., & Böge, K. (2026) · Schizophrenia Bulletin · doi:10.1093/schbul/sbae198 · Cited by 4 · see citing works
- Authors
- Hasan, A., Falkai, P., Lehmann, I., Janssen, B., Wobrock, T., Zielasek, J., & Gaebel, W.
- Affiliations
- LMU Klinikum (DE)
- Klinik und Poliklinik für Psychiatrie und Psychotherapie (DE)
- LVR-Klinik Köln (DE)
- LVR-Klinik Langenfeld (DE)
- Universitätsmedizin Göttingen (DE)
- Corresponding author
- Hasan, Alkomiet
- Venue
- Der Nervenarzt
- Published
- 2019-10-11
- Volume
- 91
- Issue
- 1
- Pages
- 26-33
- ISSN
- 0028-2804 (ISSN-L)
- 1433-0407
- OpenAlex
- W2980171006
- Cited by
- 18
- References
- 1
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 2 · 2023: 4 · 2022: 2 · 2021: 3 · 2020: 2
- FWCI
- 1.40
- Type
- journal article
- Language
- de
- Open access
- closed
- Locations
- Der Nervenarzt (publishedVersion)
- PubMed (publishedVersion)
- OPUS (Augsburg University) (submittedVersion)
- Europe PMC (PubMed Central)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Keywords
- schizophrenia, S3 guideline, antipsychotic drugs, schizophrenia diagnosis, comorbidities, psychotherapy, psychosocial interventions, rehabilitation, care coordination, cost-effectiveness, interprofessional collaboration, therapeutic relationship, stigma, quality management
- MeSH terms
- Humans, Psychotherapy, Psychotic Disorders, Schizophrenia, Antipsychotic Agents
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