The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Randle, P. J., Garland, P. B., Hales, C. N., & Newsholme, E. A. (1963) · The Lancet · doi:10.1016/s0140-6736(63)91500-9 · Cited by 5,093
Romijn, J. A., Coyle, E. F., Sidossis, L. S., Gastaldelli, A., Horowitz, J. F., Endert, E., & Wolfe, R. R. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.3.e380 · Cited by 1,747
Dresner, A., Laurent, D., Marcucci, M., Griffin, M. E., Dufour, S., Cline, G. W., Slezak, L. A., Andersen, D. K., Hundal, R. S., Rothman, D. L., et al. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5001 · Cited by 1,311
Griffin, M. E., Marcucci, M. J., Cline, G. W., Bell, K., Barucci, N., Lee, D., Goodyear, L. J., Kraegen, E. W., White, M. F., & Shulman, G. I. (1999) · Diabetes · doi:10.2337/diabetes.48.6.1270 · Cited by 1,267
Splanchnic lipolysis in human obesity
Nielsen, S., Guo, Z., Johnson, C. M., Hensrud, D. D., & Jensen, M. D. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21047 · Cited by 933
Perseghin, G., Price, T. B., Petersen, K. F., Roden, M., Cline, G. W., Gerow, K., Rothman, D. L., & Shulman, G. I. (1996) · New England Journal of Medicine · doi:10.1056/nejm199610313351804 · Cited by 699
Influence of body fat distribution on free fatty acid metabolism in obesity.
Jensen, M. D., Haymond, M. W., Rizza, R. A., Cryer, P. E., & Miles, J. M. (1989) · Journal of Clinical Investigation · doi:10.1172/jci113997 · Cited by 683
Santomauro, A. T., Boden, G., Silva, M. E., Rocha, D. M., Santos, R. F., Ursich, M. J., Strassmann, P. G., & Wajchenberg, B. L. (1999) · Diabetes · doi:10.2337/diabetes.48.9.1836 · Cited by 431 · cited 1×
“shown to reduce NEFA and improve insulin sensitivity of glucose uptake in obese subjects [42].”
Ryysy, L., Häkkinen, A. M., Goto, T., Vehkavaara, S., Westerbacka, J., Halavaara, J., & Yki-Järvinen, H. (2000) · Diabetes · doi:10.2337/diabetes.49.5.749 · Cited by 431
Seppala-Lindroos, A. (2002) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.7.3023 · Cited by 168
Research works printed but not linked: 33
- Ruderman N, Chisholm D, Pi-Sunyer X, Schneider S (1998) The metabolically obese, normal-weight individual revisited. Diabetes 47:699–713 · DOI · Paper page
- Horowitz JF, Coppack SW, Klein S (2001) Whole-body and adipose tissue glucose metabolism in response to short-term fasting in lean and obese women. Am J Clin Nutr 73:517–522 · DOI
- Boden G (1998) Free fatty acids (FFA), a link between obesity and insulin resistance. Front Biosci 3:D169–D175 · DOI
- Roden M, Krssak M, Stingl H et al (1999) Rapid impairment of skeletal muscle glucose transport/phosphorylation by free fatty acids in humans. Diabetes 48:358–364 · DOI · Paper page
- Wiesenthal SR, Sandhu H, McCall RH et al (1999) Free fatty acids impair hepatic insulin extraction in vivo. Diabetes 48:766–774 · DOI · Paper page
- Stein DT, Esser V, Stevenson BE et al (1996) Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. J Clin Invest 97:2728–2735 · DOI · Paper page
- Virkamaki A, Korsheninnikova E, Seppala-Lindroos A et al (2001) Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle. Diabetes 50:2337–2343 · DOI · Paper page
- Boden G (1997) Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:3–10 · DOI · Paper page
- Meek SE, Nair KS, Jensen MD (1999) Insulin regulation of regional free fatty acid metabolism. Diabetes 48:10–14 · DOI · Paper page
- Borg G, Linderholm H (1967) Perceived exertion and pulse rate during graded exercise in various age groups. Acta Med Scand (Suppl) 472:194–206 · DOI · Paper page
- Eriksson J, Taimela S, Koivisto VA (1997) Exercise and the metabolic syndrome. Diabetologia 40:125–135 · DOI · Paper page
- Gibney J, Healy ML, Stolinski M et al (2003) Effect of growth hormone (GH) on glycerol and free fatty acid metabolism during exhaustive exercise in GH-deficient adults. J Clin Endocrinol Metab 88:1792–1797 · DOI
- Brackenridge A, Pearson ER, Shojaee-Moradie F, Hattersley AT, Russell-Jones D, Umpleby AM (2006) Contrasting insulin sensitivity of endogenous glucose production rate in subjects with hepatocyte nuclear factor-1beta and-1alpha mutations. Diabetes 55:405–411 · DOI
- Rico-Sanz J, Thomas EL, Jenkinson G, Mierisova S, Iles R, Bell JD (1999) Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by (1)H-MRS. J Appl Physiol 87:2068–2072 · DOI
- Szczepaniak LS, Nurenberg P, Leonard D et al (2005) Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab 288:E462–E468 · DOI · Paper page
- Rendell M, Hulthen UL, Tornquist C, Groop L, Mattiasson I (2001) Relationship between abdominal fat compartments and glucose and lipid metabolism in early postmenopausal women. J Clin Endocrinol Metab 86:744–749
- Shojaee-Moradie F, Jackson NC, Jones RH, Mallet AI, Hovorka R, Umpleby AM (1996) Quantitative measurement of 3-O-methyl-d-glucose by gas chromatography-mass spectrometry as a measure of glucose transport in vivo. J Mass Spectrom 31:961–966 · DOI
- Sonksen PH (1976) Double antibody technique for the simultaneous assay of insulin and growth hormone. In: Antoniades HN (ed) Hormones in human blood: detection and assay. Harvard University Press, Cambridge, MA, pp 176–199
- Steele R, Bishop JS, Dunn A, Altszuler N, Rathbeb I, Debodo RC (1965) Inhjbition by insulin of hepatic glucose production in the normal dog. Am J Physiol 208:301–306 · DOI
- Finegood DT, Bergman RN, Vranic M (1987) Estimation of endogenous glucose production during hyperinsulinemic–euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 36:914–924 · DOI · Paper page
- Finegood DT, Bergman RN (1983) Optimal segments: a method for smoothing tracer data to calculate metabolic fluxes. Am J Physiol 244:E472–E479
- DeFronzo RA, Sherwin RS, Kraemer N (1987) Effect of physical training on insulin action in obesity. Diabetes 36:1379–1385 · DOI · Paper page
- Eriksson J, Taimela S, Koivisto VA (1997) Exercise and the metabolic syndrome. Diabetologia 40:125–135 · DOI · Paper page
- DiPietro L, Dziura J, Yeckel CW, Neufer PD (2006) Exercise and improved insulin sensitivity in older women: evidence of the enduring benefits of higher intensity training. J Appl Physiol 100:142–149 · DOI · Paper page
- Hughes VA, Fiatarone MA, Fielding RA et al (1993) Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance. Am J Physiol 264:E855–E862
- Eckel RH, Yost TJ, Jensen DR (1995) Alterations in lipoprotein lipase in insulin resistance. Int J Obes Relat Metab Disord 19(Suppl 1):S16–S21
- Miyashita Y, Ebisuno M, Ohhira M et al (2006) Enhancement of serum lipoprotein lipase mass levels by intensive insulin therapy. Diabetes Res Clin Pract 72:61–67 · DOI
- Bevilacqua S, Bonadonna R, Buzzigoli G et al (1987) Acute elevation of free fatty acid levels leads to hepatic insulin resistance in obese subjects. Metabolism 36:502–506 · DOI · Paper page
- Saloranta C, Franssila-Kallunki A, Ekstrand A, Taskinen MR, Groop L (1991) Modulation of hepatic glucose production by non-esterified fatty acids in type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34:409–415 · DOI
- Svedberg J, Bjorntorp P, Smith U, Lonnroth P (1990) Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes. Diabetes 39:570–574 · DOI · Paper page
- Krebs M, Krssak M, Nowotny P et al (2001) Free fatty acids inhibit the glucose-stimulated increase of intramuscular glucose-6-phosphate concentration in humans. J Clin Endocrinol Metab 86:2153–2160
- Kelley DE, McKolanis TM, Hegazi RA, Kuller LH, Kalhan SC (2003) Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance. Am J Physiol Endocrinol Metab 285:E906–E916 · DOI · Paper page
- Frost GS, Goff LM, Hamilton G et al (2003) Carbohydrate-induced manipulation of insulin sensitivity independently of intramyocellular lipids. Br J Nutr 89:365–375 · DOI
Cited by
Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases
Pedersen, B. K., & Saltin, B. (2015) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/sms.12581 · Cited by 3,514
Metabolic Syndrome and Insulin Resistance: Underlying Causes and Modification by Exercise Training
Roberts, C. K., Hevener, A. L., & Barnard, R. J. (2013) · Comprehensive Physiology · doi:10.1002/cphy.c110062 · Cited by 831
Johnson, N. A., Sachinwalla, T., Walton, D. W., Smith, K., Armstrong, A., Thompson, M. W., & George, J. (2009) · Hepatology · doi:10.1002/hep.23129 · Cited by 631
Chalasani, N., Younossi, Z., Lavine, J. E., Diehl, A. M., Brunt, E. M., Cusi, K., Charlton, M., & Sanyal, A. J. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2012.128 · Cited by 585
Exercise and non-alcoholic fatty liver disease: A systematic review and meta-analysis
Keating, S. E., Hackett, D. A., George, J., & Johnson, N. A. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.02.023 · Cited by 537
Metadata
- Authors
- Shojaee-Moradie, F., Baynes, K. C. R., Pentecost, C., Bell, J. D., Thomas, E. L., Jackson, N. C., Stolinski, M., Whyte, M., Lovell, D., Bowes, S. B., Gibney, J., Jones, R. H., & Umpleby, A. M.
- Venue
- Diabetologia
- Published
- 2006-12-06
- Volume
- 50
- Issue
- 2
- Pages
- 404-413
- ISSN
- 0012-186X (ISSN-L)
- 1432-0428
- OpenAlex
- W1975525226
- Cited by
- 209
- References
- 12
- FWCI
- 8.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.springer.com/tdm (tdm)
- www.springer.com/tdm (vor)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism. https://app.cochat.ai/papers/10.1007/s00125-006-0498-7
- The paper
- Shojaee-Moradie, F., Baynes, K. C. R., Pentecost, C., Bell, J. D., Thomas, E. L., Jackson, N. C., Stolinski, M., Whyte, M., Lovell, D., Bowes, S. B., Gibney, J., Jones, R. H., & Umpleby, A. M. (2007). Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism. Diabetologia. https://doi.org/10.1007/s00125-006-0498-7
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.