Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

Baekkeskov, S., Aanstoot, H.-J., Christgai, S., Reetz, A., Solimena, M., Cascalho, M., Folli, F., Richter-Olesen, H., & Camilli, P.-D. (1990) · Nature · doi:10.1038/347151a0 · Cited by 1,964

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

Atkinson, M. A., & Eisenbarth, G. S. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05415-0 · Cited by 1,491

Insulin antibodies in insulin-dependent diabetics before insulin treatment

Palmer, J. P., Asplin, C. M., Clemons, P., Lyen, K., Tatpati, O., Raghu, P. K., & Paquette, T. L. (1983) · Science · doi:10.1126/science.6362005 · Cited by 1,078

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

Wenzlau, J. M., Juhl, K., Yu, L., Moua, O., Sarkar, S. A., Gottlieb, P., Rewers, M., Eisenbarth, G. S., Jensen, J., Davidson, H. W., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705894104 · Cited by 1,014

Incidence of diabetes in youth in the United States

SEARCH for Diabetes in Youth Study Group*, T. W. G. F. T. (2007) · JAMA · doi:10.1001/jama.297.24.2716 · Cited by 991

Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero

Mold, J. E., Michaëlsson, J., Burt, T. D., Muench, M. O., Beckerman, K., Busch, M. P., Lee, T., Nixon, D. F., & McCune, J. M. (2008) · Science · doi:10.1126/science.1164511 · Cited by 840

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study.

Ziegler, A., Hummel, M., Schenker, M., & Bonifacio, E. E. (1999) · Diabetes · doi:10.2337/diabetes.48.3.460 · Cited by 640

Longitudinal Reproductive Hormone Profiles in Infants: Peak of Inhibin B Levels in Infant Boys Exceeds Levels in Adult Men1

Andersson, A., Toppari, J., Haavisto, A., Petersen, J. H., Simell, T. T., Simell, O., & Skakkebæk, N. E. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.2.4603 · Cited by 396

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy.

Kassem, S., Ariel, I., THORNTON, P. S., Scheimberg, I. B., & Gläser, B. (2000) · Diabetes · doi:10.2337/diabetes.49.8.1325 · Cited by 361

Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

Turley, S. J., Poirot, L., Hattori, M., Benoist, C. O., & Mathis, D. J. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030966 · Cited by 357

The Changing Landscape of Type 1 Diabetes: Recent Developments and Future Frontiers

Vehik, K., Ajami, N. J., Hadley, D., Petrosino, J. F., & Burkhardt, B. R. (2013) · Current Diabetes Reports · doi:10.1007/s11892-013-0406-8 · Cited by 27

Screening of ZnT8 autoantibodies in the diagnosis of autoimmune diabetes in a large French cohort

Garnier, L., Marchand, L., Benoit, M., Nicolino, M. P., Bendelac, N., Wright, C. C., Moulin, P., Lombard, C., Thivolet, C. H., & Fabien, N. (2017) · Clinica Chimica Acta · doi:10.1016/j.cca.2017.12.043 · Cited by 26

Personalized Immunotherapies for Type 1 Diabetes: Who, What, When, and How?

Deligne, C., You, S., & Mallone, R. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12040542 · Cited by 26

Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young

Frohnert, B. I., Laimighofer, M., Krumsiek, J., Theis, F. J., Winkler, C., Norris, J. M., Ziegler, A., Rewers, M., & Steck, A. K. (2017) · Pediatric Diabetes · doi:10.1111/pedi.12543 · Cited by 28

Recommendations for Screening and Monitoring the Stages of Type 1 Diabetes in the Immune Therapy Era

Moore, D. J., Leibel, N. I., Polonsky, W. H., & Rodriguez, H. (2024) · International Journal of General Medicine · doi:10.2147/ijgm.s438009 · Cited by 25

The role of B cells in the pathogenesis of type 1 diabetes

Wang, Y., Li, R., Huang, Y., Chen, H., Nie, H., Liu, L., Zou, X., Zhong, J., Zheng, B., & Gong, Q. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1450366 · Cited by 24

Autoantibody‐defined risk for Type 1 diabetes mellitus in a general population of schoolchildren: results of the Karlsburg Type 1 Diabetes Risk Study after 18 years

Till, A. ‐., Kenk, H., Rjasanowski, I. M., Waßmuth, R., Walschus, U., Kerner, W., & Schlosser, M. (2014) · Diabetic Medicine · doi:10.1111/dme.12677 · Cited by 25

Maternal Microchimerism: Increased in the Insulin Positive Compartment of Type 1 Diabetes Pancreas but Not in Infiltrating Immune Cells or Replicating Islet Cells

Ye, Y., Vives‐Pi, M., & Gillespie, K. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086985 · Cited by 24

Interleukin-7 and Type 1 Diabetes

Monti, P., & Bonifacio, E. E. (2014) · Current Diabetes Reports · doi:10.1007/s11892-014-0518-9 · Cited by 24

Autoimmunity to tetraspanin-7 in type 1 diabetes

McLaughlin, K. A., Tombs, M. A., & Christie, M. R. (2020) · Medical Microbiology and Immunology · doi:10.1007/s00430-020-00674-2 · Cited by 25

Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease

Ziegler, A., Bonifacio, E. E., Powers, A. C., Todd, J. A., Harrison, L. C., & Atkinson, M. A. (2016) · Diabetes · doi:10.2337/db16-0687 · Cited by 23

High frequency of autoantibodies in patients with long duration type 1 diabetes

Richardson, C. C., Dromey, J. A., McLaughlin, K. A., Morgan, D., Bodansky, H. J., Feltbower, R. G., Barnett, A. H., Gill, G. V., Bain, S. C., & Christie, M. R. (2013) · Diabetologia · doi:10.1007/s00125-013-3017-7 · Cited by 23

Early Onset of Diabetes in the Proband Is the Major Determinant of Risk in HLA DR3-DQ2/DR4-DQ8 Siblings

Gillespie, K., Aitken, R. J., Wilson, I. V., Williams, A., & Bingley, P. (2014) · Diabetes · doi:10.2337/db13-0994 · Cited by 24

Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies

Niegowska, M., Paccagnini, D., Mannu, C., Targhetta, C., Songini, M., & Sechi, L. (2015) · Journal of Diabetes Research · doi:10.1155/2016/5842701 · Cited by 20

Age, HLA, and Sex Define a Marked Risk of Organ-Specific Autoimmunity in First-Degree Relatives of Patients With Type 1 Diabetes

Winkler, C., Jolink, M., Knopff, A., Kwarteng, N.-A., Achenbach, P., Bonifacio, E. E., & Ziegler, A. (2019) · Diabetes Care · doi:10.2337/dc19-0315 · Cited by 21

Screening and care for preclinical stage 1–2 type 1 diabetes in first-degree relatives: French expert position statement

Mallone, R., Bismuth, É., Thivolet, C. H., Benhamou, P., Hoffmeister, N., Collet, F., Nicolino, M. P., Reynaud, R., & Beltrand, J. (2024) · Diabetes & Metabolism · doi:10.1016/j.diabet.2024.101603 · Cited by 23

Gene expression signature predicts rate of type 1 diabetes progression

Suomi, T., Starskaia, I., Ullah, U., Rasool, O., Jaakkola, M. K., Grönroos, T., Välikangas, T., Brorsson, C., Mazzoni, G., Bruggraber, S. F. A., et al. (2023) · EBioMedicine · doi:10.1016/j.ebiom.2023.104625 · Cited by 20

Enteroviral Infections as a Trigger for Type 1 Diabetes

Calvo, T. R. (2018) · Current Diabetes Reports · doi:10.1007/s11892-018-1077-2 · Cited by 22

Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children

Nilsson, A.-L., Vaziri‐Sani, F., Andersson, C. K., Larsson, K., Carlsson, A., Cedervall, E., Jönsson, B., Neiderud, J., Larsson, H. E., Ivarsson, S.-A., et al. (2013) · Viral Immunology · doi:10.1089/vim.2013.0008 · Cited by 20

High frequency of activated NKp46+natural killer cells in patients with new diagnosed of latent autoimmune diabetes in adults

Wang, Y., Yuan, W., Guo, H., & Jiang, Y. (2014) · Autoimmunity · doi:10.3109/08916934.2014.990629 · Cited by 19

Characteristics ofin-vitrophenotypes of glutamic acid decarboxylase 65 autoantibodies in high-titre individuals

Chéramy, M., Hampe, C. S., Ludvigsson, J., & Casas, R. (2012) · Clinical & Experimental Immunology · doi:10.1111/cei.12026 · Cited by 19

Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies

Maziarz, M., Hagopian, W., Palmer, J. P., Sanjeevi, C. B., Kockum, I. S., Breslow, N. E., Lernmark, Å., Graham, J., MacNeney, B., Arnqvist, H. J., et al. (2015) · Genes and Immunity · doi:10.1038/gene.2015.43 · Cited by 19

Characterization and non-parametric modeling of the developing serum proteome during infancy and early childhood

Lietzén, N., Cheng, L., Moulder, R., Siljander, H., Laajala, E., Härkönen, T., Peet, A., Vehtari, A., Tillmann, V., Knip, M., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-24019-5 · Cited by 18

Landmark models to define the age-adjusted risk of developing stage 1 type 1 diabetes across childhood and adolescence

Hoffmann, V. S., Weiß, A., Winkler, C., Knopff, A., Jolink, M., Bonifacio, E. E., & Ziegler, A. (2019) · BMC Medicine · doi:10.1186/s12916-019-1360-3 · Cited by 18

The measurement of autoantibodies to insulin informs diagnosis of diabetes in a childhood population negative for other autoantibodies

Williams, C. L., Aitken, R. J., Wilson, I. V., Mortimer, G., Long, A. E., Williams, A. J. K., The BOX Study Group, & Gillespie, K. M. (2022) · Diabetic Medicine · doi:10.1111/dme.14979 · Cited by 18

A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes

Sebastiani, G., Grieco, G. E., Bruttini, M., Auddino, S., Mori, A., Toniolli, M., Fignani, D., Licata, G., Aiello, E., Nigi, L., et al. (2024) · Cell Reports Medicine · doi:10.1016/j.xcrm.2024.101591 · Cited by 18

Prevention of Type 1 Diabetes: Past Experiences and Future Opportunities

Beik, P., Ciesielska, M., Kucza, M., Kurczewska, A., Kuźmińska, J., Maćkowiak, B., & Niechciał, E. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9092805 · Cited by 18

Associations of growth patterns and islet autoimmunity in children with increased risk for type 1 diabetes: a functional analysis approach

Yassouridis, C., Leisch, F., Winkler, C., Ziegler, A., & Beyerlein, A. (2016) · Pediatric Diabetes · doi:10.1111/pedi.12368 · Cited by 19

Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebo-controlled, primary prevention trial

Ziegler, A., Achenbach, P., Weiß, A., Berner, R., Casteels, K., Larsson, H. E., Haupt, F., Hommel, A., Jacobs, A., Kordonouri, O., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01726-x · Cited by 21

A novel, high-performance, low-volume, rapid luciferase immunoprecipitation system (LIPS) assay to detect autoantibodies to zinc transporter 8

Williams, C. L., Marzinotto, I., Brigatti, C., Gillespie, K. M., The BOX Study Group, Wilson, I. S., Aitken, R. J., Megson, C., Ballav, C., Dutta, A. K., et al. (2023) · Clinical & Experimental Immunology · doi:10.1093/cei/uxad139 · Cited by 19

HLA-DR4–Associated T and B Cell Responses to Specific Determinants on the IA-2 Autoantigen in Type 1 Diabetes

McLaughlin, K. A., Gulati, K., Richardson, C. C., Morgan, D., Bodansky, H. J., Feltbower, R. G., & Christie, M. R. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1301902 · Cited by 16

Historical Insights and Current Perspectives on the Diagnosis and Management of Presymptomatic Type 1 Diabetes

Simmons, K. M., Frohnert, B. I., O’Donnell, H. K., BAUTISTA, K. A., Rasmussen, C. G., Gonzalez, A. G., Steck, A. K., & Rewers, M. (2023) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2023.0276 · Cited by 16

Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study

Thorsen, S. U., Pipper, C. B., Eising, S., Skogstrand, K., HOUGAARD, D. M., Svensson, J., & Pociot, F. (2016) · Clinical Immunology · doi:10.1016/j.clim.2016.11.007 · Cited by 15

Four decades of the Bart’s Oxford study: Improved tests to predict type 1 diabetes

Gillespie, K. M., Fareed, R., & Mortimer, G. (2021) · Diabetic Medicine · doi:10.1111/dme.14717 · Cited by 16

Diabetes mellitus in childhood: an emerging condition in the 21st century

Manna, T. D., Setian, N., Savoldelli, R. D., Guedes, D. R., Kuperman, H., Filho, H. C. M., Steinmetz, L., Cominato, L., Dichtchekenian, V., & Damiani, D. (2016) · Revista da Associação Médica Brasileira · doi:10.1590/1806-9282.62.06.594 · Cited by 17

Auto-Antikörper-Diagnostik in der Diabetologie – Aktueller Stand der Analytik und klinische Anwendung in Deutschland

Thaler, M., Roos, M., Petersmann, A., Seißler, J., Peter, A., Landgraf, R., Müller, U., Müller‐Wieland, D., Nauck, M. A., Heinemann, L., et al. (2022) · Diabetologie und Stoffwechsel · doi:10.1055/a-1744-2856 · Cited by 14

Compromised immune response in infants at risk for type 1 diabetes born by Caesarean Section

Puff, R., D’Orlando, O., Heninger, A., Kühn, D., Krause, S. W., Winkler, C., Beyerlein, A., Bonifacio, E. E., & Ziegler, A. (2015) · Clinical Immunology · doi:10.1016/j.clim.2015.06.008 · Cited by 14

Stratifying risk for onset of type 1 diabetes using islet autoantibody trajectory clustering

Mistry, S., Gouripeddi, R., Raman, V. S., & Facelli, J. C. (2022) · Diabetologia · doi:10.1007/s00125-022-05843-x · Cited by 12

Longitudinal monitoring of gene expression in ultra-low-volume blood samples self-collected at home

Speake, C., Whalen, E., Gersuk, V. H., Chaussabel, D., Odegard, J., & Greenbaum, C. J. (2016) · Clinical & Experimental Immunology · doi:10.1111/cei.12916 · Cited by 13

Antibodies against Proinsulin and Homologous MAP Epitopes Are Detectable in Hashimoto’s Thyroiditis Sardinian Patients, an Additional Link of Association

Niegowska, M., Paccagnini, D., Burrai, C., Palermo, M., & Sechi, L. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133497 · Cited by 13

Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?

Rønningen, K. S. (2015) · BioMed Research International · doi:10.1155/2015/321656 · Cited by 13

Vaccinations in early life are not associated with development of islet autoimmunity in type 1 diabetes high-risk children: results from prospective cohort data.

Beyerlein, A., Strobl, A. N., Winkler, C., Carpus, M., Knopff, A., Donnachie, E., Ankerst, D. P., & Ziegler, A.-G. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.02.049 · Cited by 13

Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D

Niegowska, M., Rapini, N., Biet, F., Piccinini, S., Bay, S., Lidano, R., Bitti, M. L. M., & Sechi, L. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157962 · Cited by 13

From Prediction to Prevention: The Intricacies of Islet Autoantibodies in Type 1 Diabetes

Khine, A., & Quandt, Z. (2025) · Current Diabetes Reports · doi:10.1007/s11892-025-01595-1 · Cited by 12

Perceptions and understanding of family pediatricians regarding the new Italian Type 1 Diabetes screening program

Mari, J., Solidoro, S., Braida, C., Tamaro, G., Faleschini, E., & Tornese, G. (2024) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2024.111931 · Cited by 11

100 Years of insulin: Lifesaver, immune target, and potential remedy for prevention

Ziegler, A., Danne, T., Daniel, C., & Bonifacio, E. E. (2021) · Med · doi:10.1016/j.medj.2021.08.003 · Cited by 13

Extended family history of type 1 diabetes in HLA ‐predisposed children with and without islet autoantibodies

Kuusela, S., Keskinen, P., Pokka, T. M.-L., Knip, M., Ilonen, J., Vähäsalo, P., & Veijola, R. (2020) · Pediatric Diabetes · doi:10.1111/pedi.13122 · Cited by 11

Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection

Schreiber, M., Weigelt, M., Karasinsky, A., Anastassiadis, K., Schallenberg, S., Petzold, C., Bonifacio, E. E., Kretschmer, K., & Hommel, A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00742 · Cited by 11

Identification of a type 1 diabetes–associated T cell receptor repertoire signature from the human peripheral blood

Rawat, P., Shapiro, M. R., Peters, L. D., Widrich, M., Mayer-Blackwell, K., Motwani, K., Pavlović, M., al Hajj, G., Posgai, A. L., Kanduri, C., et al. (2026) · Science Advances · doi:10.1126/sciadv.adx7448 · Cited by 21

Developmental beta-cell death orchestrates the islet’s inflammatory milieu by regulating immune system crosstalk

Akhtar, M. N., Hnatiuk, A., Delgadillo-Silva, L. F., Geravandi, S., Sameith, K., Reinhardt, S., Bernhardt, K., Singh, S. P., Maedler, K., Brusch, L., et al. (2025) · The EMBO Journal · doi:10.1038/s44318-024-00332-w · Cited by 10

Evaluation of Candidate Biomarkers of Type 1 Diabetes via the Core for Assay Validation

Speake, C., & Odegard, J. (2015) · Biomarker Insights · doi:10.4137/bmi.s29697 · Cited by 10

Prevalence of autoantibodies in type 1 diabetes mellitus pediatrics in Mazandaran, North of Iran

Zamanfar, D., Aarabi, M., Amini, M., & Monajati, M. (2020) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2019-0396 · Cited by 10

Inverse association of insulin antibody levels with insulin sensitivity in adults with Type 1 diabetes

Burkart, V., Straßburger, K., Zivehe, F., Markgraf, D. F., Herder, C., Müssig, K., Szendroedi, J., Schloot, N. C., Roden, M., & the GDS Group (2018) · Diabetic Medicine · doi:10.1111/dme.13608 · Cited by 15

Novel minor HLA DR associated antigens in type 1 diabetes

Müller, D., Telieps, T., Eugster, A., Weinzierl, C., Jolink, M., Ziegler, A., & Bonifacio, E. E. (2018) · Clinical Immunology · doi:10.1016/j.clim.2018.07.001 · Cited by 10

Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4+ T Cells in Offspring

Knoop, J., Eugster, A., Gavrisan, A., Lickert, R., Sedlmeier, E.-M., Dietz, S., Lindner, A., Warncke, K., Hummel, N., Ziegler, A., et al. (2020) · Diabetes · doi:10.2337/db19-0751 · Cited by 9

Toward Primary Prevention of Type 1 Diabetes

Skyler, J. S. (2015) · JAMA · doi:10.1001/jama.2015.2054 · Cited by 10

Identification of a type 1 diabetes-associated T cell receptor repertoire signature from the human peripheral bloodPreprint

Rawat, P., Shapiro, M. R., Peters, L. D., Widrich, M., Mayer-Blackwell, K., Motwani, K., Pavlović, M., Hajj, G. S. A., Posgai, A. L., Kanduri, C., et al. (2024) · medRxiv · doi:10.1101/2024.12.10.24318751 · Cited by 10

Early-childhood body mass index and its association with the COVID-19 pandemic, containment measures and islet autoimmunity in children with increased risk for type 1 diabetes

Hummel, S., Rosenberger, S., Berge, T. V. D., Besser, R. E. J., Casteels, K., Hommel, A., Kordonouri, O., Larsson, H. E., Lundgren, M., Marcus, B. A., et al. (2024) · Diabetologia · doi:10.1007/s00125-023-06079-z · Cited by 10

The Current Landscape for Screening and Monitoring of Early‐Stage Type 1 Diabetes

Narayan, K., Mikler, K., Maguire, A., Craig, M. E., & Bell, K. J. (2025) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.70016 · Cited by 10

Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic

Zeller, I., Weiss, A., Arnolds, S., Schütte-Borkovec, K., Arabi, S., Berge, T. V. D., Casteels, K., Hommel, A., Kordonouri, O., Larsson, H. E., et al. (2024) · Infection · doi:10.1007/s15010-024-02312-y · Cited by 8

Can We Prevent Type 1 Diabetes?

Beauchamp, G., & Haller, M. J. (2015) · Current Diabetes Reports · doi:10.1007/s11892-015-0658-6 · Cited by 8

Clinical and biochemical features at diagnosis of type 1 diabetes in patients between 0 and 18 years of age from Jordan

Odeh, R., Alassaf, A. A., & Ajlouni, K. M. (2017) · Pediatric Diabetes · doi:10.1111/pedi.12625 · Cited by 8

Heritability of thyroid peroxidase autoantibody levels in type 1 diabetes: evidence from discordant twin pairs

Wang, B., Hawa, M. I., Rijsdijk, F. V., Fain, P. R., Paschou, S. Α., Boehm, B. O., Steck, A. K., Snieder, H., & Leslie, R. D. (2015) · Diabetologia · doi:10.1007/s00125-015-3664-y · Cited by 8

What Have Slow Progressors Taught Us About T1D—Mind the Gap!

Gillespie, K. M., & Long, A. E. (2019) · Current Diabetes Reports · doi:10.1007/s11892-019-1219-1 · Cited by 8

Dépistage et prise en charge du diabète de type 1 préclinique, stade 1–2. Prise de position d’experts français

Mallone, R., Bismuth, É., Thivolet, C., Benhamou, P., Hoffmeister, N., Collet, F., Nicolino, M. P., Reynaud, R., Beltrand, J., Beltrand, J., et al. (2024) · Médecine des Maladies Métaboliques · doi:10.1016/j.mmm.2024.06.003 · Cited by 8

Worth the wait: type 1 diabetes prospective birth cohort studies enter adolescence

Williams, A. J. K., & Bingley, P. J. (2012) · Diabetologia · doi:10.1007/s00125-012-2583-4 · Cited by 7

Type 1 Diabetes: Prospective Cohort Studies for Identification of the Environmental Trigger

Rønningen, K. S. (2013) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-013-0247-9 · Cited by 7

Maternal microchimerism

Ye, Y., Vives‐Pi, M., & Gillespie, K. M. (2014) · Chimerism · doi:10.4161/chim.29870 · Cited by 7

Autoimmune (Type 1) Diabetes

Lindbladh, I., Svärd, A. A., & Lernmark, Å. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812102-3.00041-5 · Cited by 8

What is type 1 diabetes?

Thrower, S. L., & Bingley, P. J. (2014) · Medicine · doi:10.1016/j.mpmed.2014.09.003 · Cited by 7

Islet autoimmunity and progression to type 1 diabetes in the Finnish DIPP study: comparison between genetically susceptible children with and without an affected first-degree relative

Kuusela, S., Koskenniemi, J. J., Valtanen, T., Pokka, T. M.-L., Härkönen, T., Ilonen, J., Lempainen, J., Kyrönniemi, A., Toppari, J., Knip, M., et al. (2025) · Diabetologia · doi:10.1007/s00125-025-06573-6 · Cited by 6

Association of long-term environmental exposures in pregnancy and early life with islet autoimmunity development in children in Bavaria, Germany

Badpa, M., Wolf, K., Schneider, A. E., Winkler, C., Haupt, F., Peters, A., & Ziegler, A. (2022) · Environmental Research · doi:10.1016/j.envres.2022.113503 · Cited by 6

The Impact of Dietary Factors during Pregnancy on the Development of Islet Autoimmunity and Type 1 Diabetes: A Systematic Literature Review

Johansen, V., Josefsen, K., & Antvorskov, J. (2023) · Nutrients · doi:10.3390/nu15204333 · Cited by 5

Oral Fc-Coupled Preproinsulin Achieves Systemic and Thymic Delivery Through the Neonatal Fc Receptor and Partially Delays Autoimmune Diabetes

Corcos, N., Čulina, S., Deligne, C., Lavaud, C., You, S., & Mallone, R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.616215 · Cited by 6

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Wilson, M. A. R., & Pozzilli, P. (2025) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2025.109132 · Cited by 3

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Георгиевна, К. К., Strongin, L. G., & Загайнов, В. Е. (2021) · Diabetes Mellitus · doi:10.14341/dm12308 · Cited by 2

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Ziegler, A., Rewers, M. J., Achenbach, P., Bell, K. J., Bonifacio, E., DiMeglio, L. A., Dutta, S., Larsson, H. E., Frohnert, B. I., Griffin, K., et al. (2026) · Diabetologia · doi:10.1007/s00125-026-06841-z · Cited by 4

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Giannopoulou, E. Z., Winkler, C., Chmiel, R., Matzke, C., Scholz, M., Beyerlein, A., Achenbach, P., Bonifacio, E. E., & Ziegler, A. (2015) · Diabetologia · doi:10.1007/s00125-015-3672-y · Cited by 87

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Parikka, V., Näntö-Salonen, K., Saarinen, M., Simell, T., Ilonen, J., Hyöty, H., Veijola, R., Knip, M., & Simell, O. (2012) · Diabetologia · doi:10.1007/s00125-012-2523-3 · Cited by 235

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Vehik, K., Haller, M. J., Beam, C. A., Schatz, D., Wherrett, D. K., Sosenko, J. M., Krischer, J. P., & DPT-1 Study Group (2011) · Diabetes Care · doi:10.2337/dc10-1494 · Cited by 20