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The copper binding properties of metformin – QCM-D, XPS and nanobead agglomeration

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Role of Insulin Resistance and Diabetes in the Pathogenesis and Treatment of Nonalcoholic Fatty Liver Disease

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The Bidirectional Relationship between Metabolism and Immune Responses

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Effects of metformin on the heart with ischaemia-reperfusion injury: Evidence of its benefits from in vitro, in vivo and clinical reports

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Metformin Therapy for the Management of Infertility in Women with Polycystic Ovary Syndrome

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Diabetes Therapies for Dementia

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Cardioprotective effect of metformin against doxorubicin cardiotoxicity in rats

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Dual Therapy Appears Superior to Monotherapy for Low-Income Individuals With Newly Diagnosed Type 2 Diabetes

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Therapeutic Applications of Type 2 Diabetes Mellitus Drug Metformin in Patients with Osteoarthritis

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Salicylic acid: old and new implications for the treatment of type 2 diabetes?

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Metformin induces the AP-1 transcription factor network in normal dermal fibroblasts

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Metformin prevents ischaemic ventricular fibrillation in metabolically normal pigs

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Metformin use is associated with a lower risk of uterine leiomyoma in female type 2 diabetes patients

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Pharmacogenetics: Implications for Modern Type 2 Diabetes Therapy

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Epithelial-Mesenchymal Transition Phenotype, Metformin, and Survival for Colorectal Cancer Patients with Diabetes Mellitus II

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Is metformin a viable alternative to insulin in the treatment of gestational diabetes mellitus (GDM)? Comparison of maternal and neonatal outcomes

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Metformin added to bosentan therapy in patients with pulmonary arterial hypertension associated with congenital heart defects: a pilot study

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Prenatal metformin exposure or organic cation transporter 3 knock-out curbs social interaction preference in male mice

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Pharmacogenetics of Antidiabetic Drugs

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Metformin attenuates ischemia/reperfusion-induced apoptosis of cardiac cells by downregulation of p53/microRNA-34a via activation of SIRT1

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Increased metformin dosage suppresses pro-inflammatory cytokine levels in systemic circulation and might contribute to its beneficial effects

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An intermittent exhaustion of the pool of glycogen in the human organism as a simple universal health promoting mechanism

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Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells

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Quantitative determination of metformin, saxagliptin and 5-hydroxy saxagliptin simultaneously by hydrophilic interaction liquid chromatography - electrospray ionization mass spectrometry and its application to a bioequivalence study with a single-pill combination in human

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Effects of antidiabetic medications on the relationship between type 2 diabetes mellitus and cognitive impairment

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rs622342A>C in SLC22A1 is associated with metformin pharmacokinetics and glycemic response

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Metformin reduces the Walker-256 tumor development in obese-MSG rats via AMPK and FOXO3a

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AMPK activation by A-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes

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The Role of Genetic Factors and Kidney and Liver Function in Glycemic Control in Type 2 Diabetes Patients on Long-Term Metformin and Sulphonylurea Cotreatment

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Metabolic Alterations at the Crossroad of Aging and Oncogenesis

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Capsaicin Analogues Derived from n-3 Polyunsaturated Fatty Acids (PUFAs) Reduce Inflammatory Activity of Macrophages and Stimulate Insulin Secretion by β-Cells In Vitro

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Metformin relieves H/R-induced cardiomyocyte injury through miR-19a/ACSL axis - possible therapeutic target for myocardial I/R injury

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AMP-activated Protein Kinase Suppresses Biosynthesis of Glucosylceramide by Reducing Intracellular Sugar Nucleotides

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Bidirectional Interactions Between the Gut Microbiota and Incretin-Based Therapies

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Redox dyshomeostasis modulation of the tumor intracellular environment through a metabolic intervention strategy for enhanced photodynamic therapy

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Identification of Transporter Polymorphisms Influencing Metformin Pharmacokinetics in Healthy Volunteers

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Oxamate Enhances the Anti-Inflammatory and Insulin-Sensitizing Effects of Metformin in Diabetic Mice

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Pharmacogenetics of Oral Antidiabetic Therapy

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A Gene Variant Near0 ATM Affects the Response to Metformin and Metformin Plasma Levels: A Post Hoc Analysis of an RCT

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Effect of Metformin on Peripheral Nerve Morphology in Type 2 Diabetes: A Cross-Sectional Observational Study

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AMPK dependent protective effects of metformin on tumor necrosis factor-induced apoptotic liver injury

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Therapeutic Potential of Antidiabetic Medications in the Treatment of Cognitive Dysfunction and Dementia

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Bidirectional regulation of adenosine 5′‐monophosphate–activated protein kinase activity by berberine and metformin in response to changes in ambient glucose concentration

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Estradiol ameliorates metformin-inhibited Sertoli cell proliferation via AMPK/TSC2/mTOR signaling pathway

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Metformin reduces the endotoxin-induced down-regulation of apolipoprotein E gene expression in macrophages

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Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells

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Diabetes mellitus: The pathophysiology as a canvas for management elucidation and strategies

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Cardiac aging: Molecular mechanisms and therapeutic interventions

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Therapeutic Challenges in Diabetes Prevention: We Have Not Found the “Exercise Pill”

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Metformin treatment improves depressive symptoms associated with type 2 diabetes: A 24-week longitudinal study

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Metformin reduces insulin resistance and the tendency toward hyperglycaemia and dyslipidaemia in dogs with hyperadrenocorticism

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Metformin and statin use associate with plasma protein N-glycosylation in people with type 2 diabetes

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The Effect of Metformin Use on Left Ventricular Ejection Fraction and Mortality Post-Myocardial Infarction

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Disease modifying mitochondrial uncouplers, MP101, and a slow release ProDrug, MP201, in models of Multiple Sclerosis

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Suppressor of cytokine signalling-2 controls hepatic gluconeogenesis and hyperglycemia by modulating JAK2/STAT5 signalling pathway

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Metformin Increases Cortisol Regeneration by 11βHSD1 in Obese Men With and Without Type 2 Diabetes Mellitus

Anderson, A. J., Andrew, R., Homer, N. Z. M., Jones, G. C., Smith, K., Livingstone, D. E. W., Walker, B. R., & Stimson, R. H. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2069 · Cited by 14

Porous silicon microcarriers for extended release of metformin: Design, biological evaluation and 3D kinetics modeling

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Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia

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Metformin ameliorates bile duct ligation-induced acute hepatic injury via regulation of ER stress

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Comparative effects of metformin, Pleurotus ostreatus, Nigella Sativa, and Zingiber officinale on the streptozotocin-induced diabetes mellitus in rats

Sangi, S., Bawadekji, A., & Ali, M. A. (2018) · Pharmacognosy Magazine · doi:10.4103/pm.pm_108_18 · Cited by 14

Implications of genetic variations, differential gene expression, and allele-specific expression on metformin response in drug-naïve type 2 diabetes

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Should metformin be included in fertility treatment of PCOS patients?

Haas, J., & Bentov, Y. (2017) · Medical Hypotheses · doi:10.1016/j.mehy.2017.01.012 · Cited by 13

Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)

Logie, L., Lees, Z. J., Allwood, J. W., McDougall, G. J., Beall, C., & Rena, G. (2018) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13455 · Cited by 13

AMPK activators for the prevention and treatment of neurodegenerative diseases

Neumann, N. R., Thompson, D. C., & Vasiliou, V. (2021) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2021.1991308 · Cited by 13

Harnessing Structural Data of Insulin and Insulin Receptor for Therapeutic Designs

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Association between the synonymous variant organic cation transporter 3 (OCT3)-1233G>A and the glycemic response following metformin therapy in patients with type 2 diabetes.

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Risk analysis of metformin use in prostate cancer: a national population-based study

Jo, J. K., Song, H. K., Heo, Y., Kim, M. J., & Kim, Y. J. (2023) · The Aging Male · doi:10.1080/13685538.2022.2156497 · Cited by 16

Metformin reduces risk of benign nodular goiter in patients with type 2 diabetes mellitus

Tseng, C. (2019) · European Journal of Endocrinology · doi:10.1530/eje-19-0133 · Cited by 12

Repurposing of Anticancer Stem Cell Drugs in Brain Tumors

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DMT efficiently inhibits hepatic gluconeogenesis by regulating the Gαq signaling pathway

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New Evidence for the Mechanism of Action of a Type-2 Diabetes Drug Using a Magnetic Bead-Based Automated Biosensing Platform

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A Novel Dipeptide NGF Mimetic GK-2 Selectively Activating the PI3K/AKT Signaling Pathway Promotes the Survival of Pancreatic β-Cells in a Rat Model of Diabetes

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The Effects of Accelerated Temperature-Controlled Stability Systems on the Release Profile of Primary Bile Acid-Based Delivery Microcapsules

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Biguanide Pharmaceutical Formulations and the Applications of Bile Acid-Based Nano Delivery in Chronic Medical Conditions

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Green and white MEKC for determination of different anti-diabetic binary mixtures and their triple-combo pill

Ahmed, A. R., Korany, M. A., Galal, S. M., & Ragab, M. A. A. (2023) · BMC Chemistry · doi:10.1186/s13065-023-00997-0 · Cited by 11

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Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

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Effect of Linagliptin Versus Metformin on Glycemic Variability in Patients with Impaired Glucose Tolerance

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Animal Models for Understanding the Mechanisms of Beta Cell Death during Type 2 Diabetes Pathogenesis

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Metformin Attenuates Myocardium Dicarbonyl Stress Induced by Chronic Hypertriglyceridemia

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Metformin – Postmortem fatal and non-fatal reference concentrations in femoral blood and risk factors associated with fatal intoxications

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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK

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