The DOI matches its Crossref record; 148 of the 148 references it cites were found in a registry or an index.
Acute kidney injury in the critically ill: an updated review on pathophysiology and management
Open accessAbstract
Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only affects acute morbidity and mortality, but also a patient's long-term prognosis. In this narrative review, an update on various aspects of AKI in critically ill patients will be provided. Focus will be on prediction and early detection of AKI (e.g., the role of biomarkers to identify high-risk patients and the use of machine learning to predict AKI), aspects of pathophysiology and progress in the recognition of different phenotypes of AKI, as well as an update on nephrotoxicity and organ cross-talk. In addition, prevention of AKI (focusing on fluid management, kidney perfusion pressure, and the choice of vasopressor) and supportive treatment of AKI is discussed. Finally, post-AKI risk of long-term sequelae including incident or progression of chronic kidney disease, cardiovascular events and mortality, will be addressed.
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Cites
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Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4683-6 · Cited by 6,621
Dapagliflozin in Patients with Chronic Kidney Disease
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“shown to improve clinical outcomes (mortality or progression of CKD and cardiovascular events) in CKD patients [141, 142].”
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Self-citationComparison of Two Fluid-Management Strategies in Acute Lung Injury
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“shown to improve clinical outcomes (mortality or progression of CKD and cardiovascular events) in CKD patients [141, 142].”
Background16., O. B. O. T. A. D. Q. I. W., Chawla, L. S., Bellomo, R., Bihorac, A., Goldstein, S. L., Siew, E. D., Bagshaw, S. M., Bittleman, D., Cruz, D., Endre, Z., et al. (2017) · Nature Reviews Nephrology · doi:10.1038/nrneph.2017.2 · Cited by 1,537
Self-citationGlobal epidemiology and outcomes of acute kidney injury
Hoste, E. A. J., Kellum, J. A., Selby, N. M., Zarbock, A., Palevsky, P. M., Bagshaw, S. M., Goldstein, S. L., Cerdá, J., & Chawla, L. S. (2018) · Nature Reviews Nephrology · doi:10.1038/s41581-018-0052-0 · Cited by 1,486
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Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury
Kashani, K., Al-Khafaji, A., Ardiles, T., Artigas, A., Bagshaw, S. M., Bell, M., Bihorac, A., Birkhahn, R., Cely, C. M., Chawla, L. S., et al. (2013) · Critical Care · doi:10.1186/cc12503 · Cited by 1,362
Self-citation
Cited by
Ostermann, M., Lumlertgul, N., Jeong, R., See, E., Joannidis, M., & James, M. (2025) · The Lancet · doi:10.1016/s0140-6736(24)02385-7 · Cited by 396
Self-citationBachmann, K. F., Regli, A., Mändul, M., Davis, W., & Reintam Blaser, A. (2022) · Journal of Critical Care · doi:10.1016/j.jcrc.2022.154078 · Cited by 10
Metadata
- Authors
- Pickkers, P., Darmon, M., Hoste, E., Joannidis, M., Legrand, M., Ostermann, M., Prowle, J. R., Schneider, A., & Schetz, M.
- Venue
- Intensive Care Medicine
- Published
- 2021-07-02
- Volume
- 47
- Issue
- 8
- Pages
- 835-850
- ISSN
- 0342-4642 (ISSN-L)
- 1432-1238
- OpenAlex
- W3177086065
- Cited by
- 549
- References
- 148
- FWCI
- 40.33
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- The paper
- Pickkers, P., Darmon, M., Hoste, E., Joannidis, M., Legrand, M., Ostermann, M., Prowle, J. R., Schneider, A., & Schetz, M. (2021). Acute kidney injury in the critically ill: an updated review on pathophysiology and management. Intensive Care Medicine. https://doi.org/10.1007/s00134-021-06454-7
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
