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Intensive Care Delirium Screening Checklist: evaluation of a new screening tool
Abstract
Objective Delirium in the intensive care unit is poorly defined. Clinical evaluation is difficult in the setting of unstable, often intubated patients. A screening tool may improve the detection of delirium.Method We created a screening checklist of eight items based on DSM criteria and features of delirium: altered level of consciousness, inattention, disorientation, hallucination or delusion, psychomotor agitation or retardation, inappropriate mood or speech, sleep/wake cycle disturbance, and symptom fluctuation. During 3 months, all patients admitted to a busy medical/surgical intensive care unit were evaluated, and the scale score was compared to a psychiatric evaluation.Results In 93 patients studied, 15 developed delirium. Fourteen (93%) of them had a score of 4 points or more. This score was also present in 15 (19%) of patients without delirium, 14 of whom had a known psychiatric illness, dementia, a structural neurological abnormality or encephalopathy. A ROC analysis was used to determine the sensitivity and specificity of the screening tool. The area under the ROC curve is 0.9017. Predicted sensitivity is 99% and specificity is 64%.Conclusion This study suggests that the Intensive Care Delirium Screening Checklist can easily be applied by a clinician or a nurse in a busy critical care setting to screen all patients even when communication is compromised. The tool can be utilized quickly and helps to identify delirious patients. Earlier diagnosis may lead to earlier intervention and better patient care.
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“Similarly, delirium was assessed for each patient twice daily by nurses or physicians until ICU discharge by using the Intensive Care Delirium Screening Checklist (ICDSC) score [22] (Additional data file 3).”
From Nicotine withdrawal and agitation in ventilated critically ill patients (2010) · cites this paper as [22]
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“Delirium is a syndrome characterized by the acute onset of cerebral dysfunction with a change or fluctuation in baseline mental status, inattention, and either disorganized thinking or an altered level of consciousness (307-313).”
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“Moreover, the ICDSC study included patients with neurological or psychiatric diagnoses, or abnormal consciousness on admission, and thus incorporated many patients who were excluded in substantiating the CAM-ICU [22].”
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Olanzapine vs haloperidol: treating delirium in a critical care setting
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Delirium in critical illness: clinical manifestations, outcomes, and management
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Epidemiology and risk factors for delirium across hospital settings
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Social media adoption and its impact on firm performance: the case of the UAE
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“Delirium is a clinical diagnosis; most studies detect its presence using screening tools such as the Confusion Assessment Method for the ICU (CAM-ICU) or the Intensive Care Delirium Screening Checklist (73, 74).”
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“Physicians have at their disposal validated clinical instruments for detecting brain dysfunction of critically ill patients, including the Confusion Assessment Method for the ICU (CAM-ICU) [6], and the intensive care delirium screening checklist (ICDSC) [67].”
Prevalence, Risk Factors, and Outcomes of Delirium in Mechanically Ventilated Adults*
Mehta, S., Cook, D., Devlin, J. W., Skrobik, Y. K., Meade, M. O., Fergusson, D. A., Herridge, M. S., Steinberg, M., Granton, J. T., Ferguson, N. D., et al. (2014) · Critical Care Medicine · doi:10.1097/ccm.0000000000000727 · Cited by 360
“No delirium means ICDSC was always ≤ 3.”
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Comparison of delirium assessment tools in a mixed intensive care unit*
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Symptoms experienced by intensive care unit patients at high risk of dying*
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Subsyndromal delirium in the ICU: evidence for a disease spectrum
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Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial
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Self-citationKetamine Attenuates Delirium After Cardiac Surgery With Cardiopulmonary Bypass
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“, 4) at any assessment during their ICU stay were considered to have clinical delirium.(16) Patients with a maximal ICDSC score 0 but 3 at any time during their ICU stay were considered to have subsyndromal delirium.”
BackgroundInfluentialSelf-citationThe Importance of Diagnosing and Managing ICU Delirium
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Routine Use of the Confusion Assessment Method for the Intensive Care Unit: A Multicenter Study
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“In one study, CAM-ICU was prospectively compared with the Intensive Care Delirium Screening Checklist in 126 patients.”
InfluentialPandharipande, P. P., Cotton, B. A., Shintani, A., Thompson, J. L., Costabile, S., Pun, B. T., Dittus, R. S., & Ely, E. W. (2007) · Intensive Care Medicine · doi:10.1007/s00134-007-0687-y · Cited by 268
Delirium Screening: A Systematic Review of Delirium Screening Tools in Hospitalized Patients
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“It has been shown to have an excellent sensitivity (99%); however, its specificity was lower at 64% [75], allowing other conditions to be identified incorrectly as delirium.”
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Pisani, M. A. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.15.1629 · Cited by 266
Sepsis-associated encephalopathy and its differential diagnosis
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“For delirium, the Confusion Assessment Method for the Intensive Care Unit (39) or the Intensive Care Unit Delirium Screening Checklist (40) can be proposed.”
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“Data collected included study drug rate, use of other sedatives, RASS score, Intensive Care Delirium Screening Checklist (ICDSC) score [ 16 ], requirement for physical restraint, mean arterial pressure, requirement and rate of vasopressors and inotropes, and the presence of arrhythmias or any other adverse event.”
Risk Factors for and Prediction by Caregivers of Extubation Failure in ICU Patients
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Prevention and Management of Delirium in the Intensive Care Unit
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The Preschool Confusion Assessment Method for the ICU
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MethodInfluentialSepsis Associated Encephalopathy
Chaudhry, N., & Duggal, A. K. (2014) · Advances in Medicine · doi:10.1155/2014/762320 · Cited by 254
“In nonsedated patients mental status is straightforwardly assessed by the Confusion Assessment Method (CAM) for patients outside the ICU and Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) for patients admitted to the ICU.”
Delirium assessment in the critically ill
Devlin, J. W., Fong, J. J., Fraser, G. L., & Riker, R. R. (2007) · Intensive Care Medicine · doi:10.1007/s00134-007-0603-5 · Cited by 222
“A major reason for the higher specificity that is reported with CAM-ICU (89%) than ICDSC (64%) is that patients with neurological injury and structural neurological abnormalities were excluded from the CAM-ICU but not the ICDSC validation studies [2, 32, 33].”
BackgroundMethodInfluentialThe impact of delirium on clinical outcomes in mechanically ventilated surgical and trauma patients
Lat, I., McMillian, W., Taylor, S., Janzen, J. M., Papadopoulos, S., Korth, L., Ehtisham, A., Nold, J., Agarwal, S., Azocar, R., et al. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e31819ffe38 · Cited by 222
“Several validated tools exist to assist in the diagnosis of delirium in the critically ill population (2, 3).”
MethodClinical review: The ABC of weaning failure - a structured approach
Heunks, L. M. A., & van der Hoeven, J. G. (2010) · Critical Care · doi:10.1186/cc9296 · Cited by 223
Preventing Delirium in the Intensive Care Unit
Brummel, N. E., & Girard, T. D. (2012) · Critical Care Clinics · doi:10.1016/j.ccc.2012.10.007 · Cited by 214
Critical Care Nurses’ Role in Implementing the “ABCDE Bundle” Into Practice
Balas, M. C., Vasilevskis, E. E., Burke, W. J., Boehm, L. M., Pun, B. T., Olsen, K. M., Peitz, G. J., & Ely, E. W. (2012) · Critical Care Nurse · doi:10.4037/ccn2012229 · Cited by 214
Sepsis-Associated Encephalopathy: From Delirium to Dementia?
Chung, H., Wickel, J., Brunkhorst, F. M., & Geis, C. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9030703 · Cited by 222
“In the intensive care unit, the CAM‐ICU [81] or the intensive care delirium checklist (ICDSC) [82] are most commonly used.”
MethodInfluentialValidity and Reliability of the CAM-ICU Flowsheet to diagnose delirium in surgical ICU patients
Guenther, U., Popp, J., Koecher, L., Muders, T., Wrigge, H., Ely, E. W., & Putensen, C. (2009) · Journal of Critical Care · doi:10.1016/j.jcrc.2009.08.005 · Cited by 213
Assessment of Delirium in the Intensive Care Unit: Nursing Practices And Perceptions
Devlin, J. W., Fong, J. J., Howard, E., Skrobik, Y. K., McCoy, N., Yasuda, C., & Marshall, J. (2008) · American Journal of Critical Care · doi:10.4037/ajcc2008.17.6.555 · Cited by 211
Self-citationThe intensive care delirium research agenda: a multinational, interprofessional perspective
Pandharipande, P. P., Ely, E. W., Arora, R. C., Balas, M. C., Boustani, M. A., Calle, G. H. L., Cunningham, C. M., Devlin, J. W., Elefante, J., Han, J. H., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4860-7 · Cited by 215
Self-citationICU delirium ― a diagnostic and therapeutic challenge in the intensive care unit
Kotfis, K., Marra, A., & Ely, E. W. (2018) · Anaesthesiology Intensive Therapy · doi:10.5603/ait.a2018.0011 · Cited by 220
“The scales most widely used in delirium monitoring and recommended by CCM [6] include the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) [27] and the Intensive Care Delirium Screening Checklist (ICDSC) [28].”
MethodInfluentialApolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patients*
Ely, W., Girard, T. D., Shintani, A., Jackson, J. C., Gordon, S. M., Thomason, J. W. W., Pun, B. T., Canonico, A. E., Light, R. W., Pandharipande, P. P., et al. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000251925.18961.ca · Cited by 204
Sedation and Analgesia in the Mechanically Ventilated Patient
Patel, S. B., & Kress, J. P. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201102-0273ci · Cited by 205
Morandi, A., Pandharipande, P. P., Trabucchi, M., Rozzini, R., Mistraletti, G., Trompeo, A. C., Gregoretti, C., Gattinoni, L., Ranieri, M. V., Brochard, L. J., et al. (2008) · Intensive Care Medicine · doi:10.1007/s00134-008-1177-6 · Cited by 201
“, acute change or fluctuation in mental status and inattention, accompanied by either disorganized thinking or an altered level of consciousness) [1] occurs in 20–40% of non-critically ill, hospitalized patients with rates as high as 80% in critically ill surgical and medical ICU patients [2–10], depending on the seve…”
BackgroundSelf-citationAn Updated Focused Review of Dexmedetomidine in Adults
Gerlach, A. T., Murphy, C. V., & Dasta, J. F. (2009) · Annals of Pharmacotherapy · doi:10.1345/aph.1m310 · Cited by 200
Kong, H., Xu, L., & Wang, D. (2022) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13873 · Cited by 214
Meta-Analysis of Factors Which Influence Delirium Following Cardiac Surgery
Lin, Y., Chen, J., & Wang, Z. (2012) · Journal of Cardiac Surgery · doi:10.1111/j.1540-8191.2012.01472.x · Cited by 192
Children's Factual and Delusional Memories of Intensive Care
Colville, G. A., Kerry, S., & Pierce, C. M. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200706-857oc · Cited by 193
“Opiates 94 (92) Thiopentone 4 (4) Propofol 2 (2) Paralyzing drugs 42 ( 43 )”
MethodPatient-Focused Sedation and Analgesia in the ICU
Sessler, C. N., & Gill, K. V. (2008) · CHEST Journal · doi:10.1378/chest.07-2026 · Cited by 191
Pandharipande, P. P., Banerjee, A., McGrane, S., & Ely, E. W. (2010) · Critical Care · doi:10.1186/cc8999 · Cited by 188
“Development of easy to use delirium monitoring instruments such as the Confusion Assessment Method for the ICU [11] and the Intensive Care Delirium Screening Checklist [ 12 ] (the D of the ABCDEs) led to investigations that quantifi ed the undesirable consequences of delirium in the critically ill [5-7], and identifi…”
MethodSchubert, M., Schürch, R., Böettger, S., Núñez, D. G., Schwarz, U., Béttex, D., Jenewein, J., Bogdanović, J., Stähli, M. L., Spirig, R., et al. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3345-x · Cited by 199
Prevalence and Risk Factors for Development of Delirium in Burn Intensive Care Unit Patients
Agarwal, V., O’Neill, P. J., Cotton, B. A., Pun, B. T., Haney, S., Thompson, J. L., Kassebaum, N. J., Shintani, A., Guy, J., Ely, E. W., et al. (2010) · Journal of Burn Care & Research · doi:10.1097/bcr.0b013e3181eebee9 · Cited by 185
Hagel, S., Bach, F., Brenner, T., Bracht, H., Brinkmann, A., Annecke, T., Höhn, A., Weigand, M. A., Michels, G., Kluge, S., et al. (2022) · Intensive Care Medicine · doi:10.1007/s00134-021-06609-6 · Cited by 188
Assessment scales for delirium: A review
Grover, S. (2012) · World Journal of Psychiatry · doi:10.5498/wjp.v2.i4.58 · Cited by 183
Martin, J., Heymann, A., Bäsell, K., Baron, R., Biniek, R., Bürkle, H., Dall, P., Dictus, C., Eggers, V., Eichler, I., et al. (2010) · PubMed Central · doi:10.3205/000091 · Cited by 184
“RASS: Richmond Agitation Sedation Scale (-5 to +4) VAS: Visual Analogue Scala, VRS: Verbale Rating Scala, NRS: Numeric Rating Scale (0-10) BPS: Behavioral Pain Scale (3-12), PAINAD: Pain Assessment in Advanced Dementia (0-10) CAM-ICU: Confusion Assessment Method for the ICU (positive/negative) ICDSC: Intensive Care De…”
BackgroundMethodInfluentialHayhurst, C. J., Pandharipande, P. P., & Hughes, C. G. (2016) · Anesthesiology · doi:10.1097/aln.0000000000001378 · Cited by 192
Metadata
- Authors
- Bergeron, N., Dubois, M.-J., Dumont, M., Dial, S., & Skrobik, Y.
- Affiliations
- Hôpital Maisonneuve-Rosemont (CA)
- McGill University (CA)
- Corresponding author
- Skrobik, Y.
- Venue
- Intensive Care Medicine
- Published
- 2001-04-20
- Volume
- 27
- Issue
- 5
- Pages
- 859-864
- ISSN
- 0342-4642 (ISSN-L)
- 1432-1238
- OpenAlex
- W2143617649
- Cited by
- 1,487
- References
- 0
- Citations by year
- 2026: 78 · 2025: 85 · 2024: 96 · 2023: 94 · 2022: 80 · 2021: 96 · 2020: 110 · 2019: 78 · 2018: 70 · 2017: 79 · 2016: 66 · 2015: 64 · 2014: 60 · 2013: 74 · 2012: 73
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Intensive Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Health Sciences › Medicine › Clinical Neurology › Alcoholism and Thiamine Deficiency
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Keywords
- delirium, intensive care unit, delirium screening, screening checklist, intensive care, altered level of consciousness, psychomotor agitation, sleep-wake disturbances, sensitivity and specificity, early diagnosis
- MeSH terms
- Adult, Aged, Aged, 80 and over, Critical Care, Delirium, Female, Humans, Male, Middle Aged, Prospective Studies, Surveys and Questionnaires, ROC Curve, Sensitivity and Specificity, Critical Illness, APACHE
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