Sleep difficulties are associated with increased symptoms of psychopathology
Abstract
Sleep problems often co-occur with psychopathological conditions and affective dysregulation. Individuals with mood disorders have significantly higher rates of sleep disturbances than healthy individuals, and among those with mood disorders, sleep problems are associated with lower rates of remission and response to treatment. Sleep disruption may itself be a risk factor for various forms of psychopathology, as experimental sleep deprivation has been found to lead to increased affective, cognitive, and somatic symptoms within healthy volunteers. However, little is known about the relationship between recurring sleep complaints in a naturalistic environment and symptoms of psychopathology among healthy individuals. In the present study, 49 healthy adults (21 males and 28 females) reported sleep quality and completed the Personality Assessment Inventory, a standardized self-report assessment of symptoms of psychopathology. Consistent with prior published findings during total sleep deprivation, individuals endorsing self-reported naturally occurring sleep problems showed higher scores on scales measuring somatic complaints, anxiety, and depression. Furthermore, the reported frequency of sleep disturbance was closely linked with the severity of self-reported symptoms. While causal directionality cannot be inferred, these findings support the notion that sleep and emotional functioning are closely linked.
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Sleep disruption is a symptom of TBI that can affect other known outcomes of injury.
“Sleep disruption is a symptom of TBI that can affect other known outcomes of injury because a lack of proper sleep disrupts healthy living.10–15”
From Effects of Traumatic Brain Injury on the Orexin/Hypocretin System (2025) · cites this paper as [15]
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- Authors
- Tkachenko, O., Olson, E. A., Weber, M., Preer, L. A., Gogel, H., & Killgore, W. D. S.
- Affiliations
- McLean Hospital (US)
- Harvard University (US)
- Corresponding author
- Killgore, William D. S.
- Venue
- Experimental Brain Research
- Published
- 2014-02-05
- Volume
- 232
- Issue
- 5
- Pages
- 1567-1574
- ISSN
- 0014-4819 (ISSN-L)
- 1432-1106
- OpenAlex
- W2145189201
- Cited by
- 59
- References
- 16
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 3 · 2023: 6 · 2022: 10 · 2021: 6 · 2020: 6 · 2019: 6 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 2 · 2014: 2 · 2013: 1
- FWCI
- 5.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Experimental Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- McLean Hospital
- U.S. Army Medical Research Acquisition Activity
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- sleep disorders, psychopathology, sleep quality, mood disorders, anxiety, depression, somatic symptoms, sleep deprivation, emotional dysregulation, Personality Assessment Inventory, healthy adults
- MeSH terms
- Adolescent, Adult, Analysis of Variance, Antisocial Personality Disorder, Female, Humans, Male, Middle Aged, Personality Inventory, Psychiatric Status Rating Scales, Sleep Wake Disorders, Statistics, Nonparametric, Young Adult
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