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Bioconversion of red seaweed galactans: a focus on bacterial agarases and carrageenases
Abstract
Agars and carrageenans are 1,3-alpha-1,4-beta-galactans from the cell walls of red algae, substituted by zero (agarose), one (kappa-), two (iota-), or three (lambda-carrageenan) sulfate groups per disaccharidic monomer. Agars, kappa-, and iota-carrageenans auto-associate into crystalline fibers and are well known for their gelling properties, used in a variety of laboratory and industrial applications. These sulfated galactans constitute a crucial carbon source for a number of marine bacteria. These microorganisms secrete glycoside hydrolases specific for these polyanionic, insoluble polysaccharides, agarases and carrageenases. This article reviews the microorganisms involved in the degradation of agars and carrageenans, in their environmental and taxonomic diversity. We also present an overview on the biochemistry of the different families of galactanases. The structure-function relationships of the family GH16 beta-agarases and kappa-caraggeenases and of the family GH82 iota-carrageenases are discussed in more details. In particular, we examine how the active site topologies of these glycoside hydrolases influence their mode of action in heterogeneous phase. Finally, we discuss the next challenges in the basic and applied field of the galactans of red algae and of their related degrading microorganisms.
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“The degradation of carrageenan is one of the least studied among the major cell wall carbohydrates in algae.”
From The Enzymatic Conversion of Major Algal and Cyanobacterial Carbohydrates to Bioethanol (2016) · cites this paper as Michel et al., 2006
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Metadata
- Authors
- Michel, G., Nyval-Collen, P., Barbeyron, T., Czjzek, M., & Helbert, W.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Helbert, William
- Venue
- Applied Microbiology and Biotechnology
- Published
- 2006-06
- Volume
- 71
- Issue
- 1
- Pages
- 23-33
- ISSN
- 0175-7598 (ISSN-L)
- 1432-0614
- OpenAlex
- W2001030191
- Cited by
- 240
- References
- 110
- Citations by year
- 2026: 8 · 2025: 4 · 2024: 10 · 2023: 13 · 2022: 12 · 2021: 10 · 2020: 12 · 2019: 10 · 2018: 16 · 2017: 18 · 2016: 11 · 2015: 12 · 2014: 14 · 2013: 21 · 2012: 15
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Applied Microbiology and Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Enzyme Production and Characterization
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- agarase, carrageenase, agar, carrageenan, marine bacteria, glycoside hydrolases, polysaccharide degradation, active site topology, structure-function relationship, sulfated polysaccharides, marine microbial diversity
- MeSH terms
- Agar, Rhodophyta, Bacteria, Bacterial Proteins, Binding Sites, Biodegradation, Environmental, Carrageenan, Galactans, Glycoside Hydrolases, Marine Biology, Models, Molecular, Seaweed, Structure-Activity Relationship, Sulfates
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