The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.
Bioconversion of red seaweed galactans: a focus on bacterial agarases and carrageenases
Abstract
Agars and carrageenans are 1,3-alpha-1,4-beta-galactans from the cell walls of red algae, substituted by zero (agarose), one (kappa-), two (iota-), or three (lambda-carrageenan) sulfate groups per disaccharidic monomer. Agars, kappa-, and iota-carrageenans auto-associate into crystalline fibers and are well known for their gelling properties, used in a variety of laboratory and industrial applications. These sulfated galactans constitute a crucial carbon source for a number of marine bacteria. These microorganisms secrete glycoside hydrolases specific for these polyanionic, insoluble polysaccharides, agarases and carrageenases. This article reviews the microorganisms involved in the degradation of agars and carrageenans, in their environmental and taxonomic diversity. We also present an overview on the biochemistry of the different families of galactanases. The structure-function relationships of the family GH16 beta-agarases and kappa-caraggeenases and of the family GH82 iota-carrageenases are discussed in more details. In particular, we examine how the active site topologies of these glycoside hydrolases influence their mode of action in heterogeneous phase. Finally, we discuss the next challenges in the basic and applied field of the galactans of red algae and of their related degrading microorganisms.
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“The degradation of carrageenan is one of the least studied among the major cell wall carbohydrates in algae.”
From The Enzymatic Conversion of Major Algal and Cyanobacterial Carbohydrates to Bioethanol (2016) · cites this paper as Michel et al., 2006
Citations
Cites
Structures and mechanisms of glycosyl hydrolases
Davies, G. J., & Henrissat, B. (1995) · Structure · doi:10.1016/s0969-2126(01)00220-9 · Cited by 2,118
Catalytic mechanism of enzymic glycosyl transfer
Sinnott, M. L. (1990) · Chemical Reviews · doi:10.1021/cr00105a006 · Cited by 1,537
Updating the sequence-based classification of glycosyl hydrolases
Henrissat, B., & Bairoch, A. (1996) · Biochemical Journal · doi:10.1042/bj3160695 · Cited by 1,365
STEREOCHEMISTRY AND THE MECHANISM OF ENZYMATIC REACTIONS
Koshland, D. E. (1953) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1953.tb01386.x · Cited by 1,015
The agarose double helix and its function in agarose gel structure
Arnott, S., Fulmer, A. W., Scott, W. E., Dea, I. C. M., Moorhouse, R., & Rees, D. A. (1974) · Journal of Molecular Biology · doi:10.1016/0022-2836(74)90372-6 · Cited by 789
Structure, Conformation, and Mechanism in the Formation of Polysaccharide Gels and Networks
Rees, A. (1969) · Advances in carbohydrate chemistry and biochemistry · doi:10.1016/s0065-2318(08)60352-2 · Cited by 666
Divne, C., Ståhlberg, J., Reinikainen, T., Ruohonen, L., Pettersson, G., Knowles, J. K. C., Teeri, T. T., & Jones, T. A. (1994) · Science · doi:10.1126/science.8036495 · Cited by 630
Three-Dimensional Structure of Cellobiohydrolase II from Trichoderma reesei
Rouvinen, J., Bergfors, T., Teeri, T. T., Knowles, J. K., & Jones, T. A. (1990) · Science · doi:10.1126/science.2377893 · Cited by 606
Cation-specific aggregation of carrageenan helices: Domain model of polymer gel structure
Morris, E. R., Rees, D. A., & Robinson, G. (1980) · Journal of Molecular Biology · doi:10.1016/0022-2836(80)90291-0 · Cited by 567
Michell, B. J., Chen, Z., Tiganis, T., Stapleton, D., Katsis, F., Power, D. A., Sim, A. T. R., & Kemp, B. E. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c100122200 · Cited by 560
Research works printed but not linked: 6
- Gran HH (1902) Studien über meerebakterien. II. Über die hydrolyse des agars-agars durch ein neues enzym, die gelase. Bergens Museums Arb 2:1–16
- Greer CW (1984) A study of carrageenases from marine bacteria. Thèse de Doctorat. McGill University, Montreal, Canada
- Humm HJ (1946) Marine agar digesting bacteria of the South Atlantic coast. Duke Univ Mar Stn Bull 3:43–75
- Mori T (1943) The enzyme catalyzing the decomposition of mucilage of Chondrus ocellatus. III. Purification, unit determination, and distribution of the enzyme. J Agric Chem Soc Jpn 19:740–742
- Rees DA, Morris ER, Thom D, Madden J (1982) In: Aspinall GO (ed) The polysaccharides. Academic, New York, USA, pp 195–290
- Young KS, Hong KC, Duckworth M, Yaphe W (1971) Enzymic hydrolysis of agar and properties of bacterial agarases. Proc Int Seaweed Symp 7:15–22
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Sorted by citations
Carrageenans: Biological properties, chemical modifications and structural analysis – A review
Campo, V. L., Kawano, D. F., da Silva, D. B., & Carvalho, I. (2009) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2009.01.020 · Cited by 1,412
Microbial Surface Colonization and Biofilm Development in Marine Environments
Dang, H., & Lovell, C. R. (2015) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00037-15 · Cited by 1,309
Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota
Hehemann, J.-H., Correc, G., Barbeyron, T., Helbert, W., Czjzek, M., & Michel, G. (2010) · Nature · doi:10.1038/nature08937 · Cited by 1,117
Self-citationChemical structures and bioactivities of sulfated polysaccharides from marine algae
Jiao, G., Yu, G., Zhang, J., & Ewart, H. S. (2011) · Marine Drugs · doi:10.3390/md9020196 · Cited by 1,054
Stengel, D. B., Connan, S., & Popper, Z. A. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.05.016 · Cited by 640
Metadata
- Authors
- Michel, G., Nyval-Collen, P., Barbeyron, T., Czjzek, M., & Helbert, W.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Helbert, William
- Venue
- Applied Microbiology and Biotechnology
- Published
- 2006-06
- Volume
- 71
- Issue
- 1
- Pages
- 23-33
- ISSN
- 0175-7598 (ISSN-L)
- 1432-0614
- OpenAlex
- W2001030191
- Cited by
- 240
- References
- 110
- Citations by year
- 2026: 8 · 2025: 4 · 2024: 10 · 2023: 13 · 2022: 12 · 2021: 10 · 2020: 12 · 2019: 10 · 2018: 16 · 2017: 18 · 2016: 11 · 2015: 12 · 2014: 14 · 2013: 21 · 2012: 15
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Applied Microbiology and Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Enzyme Production and Characterization
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- agarase, carrageenase, agar, carrageenan, marine bacteria, glycoside hydrolases, polysaccharide degradation, active site topology, structure-function relationship, sulfated polysaccharides, marine microbial diversity
- MeSH terms
- Agar, Rhodophyta, Bacteria, Bacterial Proteins, Binding Sites, Biodegradation, Environmental, Carrageenan, Galactans, Glycoside Hydrolases, Marine Biology, Models, Molecular, Seaweed, Structure-Activity Relationship, Sulfates
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