The DOI matches its Crossref record; 102 of the 102 references it cites were found in a registry or an index.
Advances in ovarian cancer therapy
Open accessAbstract
Epithelial ovarian cancer is typically diagnosed at an advanced stage. Current state-of-the-art surgery and chemotherapy result in the high incidence of complete remissions; however, the recurrence rate is also high. For most patients, the disease eventually becomes a continuum of symptom-free periods and recurrence episodes. Different targeted treatment approaches and biological drugs, currently under development, bring the promise of turning ovarian cancer into a manageable chronic disease. In this review, we discuss the current standard in the therapy for ovarian cancer, major recent studies on the new variants of conventional therapies, and new therapeutic approaches, recently approved and/or in clinical trials. The latter include anti-angiogenic therapies, polyADP-ribose polymerase (PARP) inhibitors, inhibitors of growth factor signaling, or folate receptor inhibitors, as well as several immunotherapeutic approaches. We also discuss cost-effectiveness of some novel therapies and the issue of better selection of patients for personalized treatment.
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Cited by
Tumor microenvironment in ovarian cancer: function and therapeutic strategy
Yang, Y., Yang, Y., Yang, J., Zhao, X., & Wei, X. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00758 · Cited by 218
Rah, B., Rather, R. A., Bhat, G. R., Baba, A. B., Mushtaq, I., Farooq, M., Yousuf, T., Dar, S. B., Parveen, S., Hassan, R., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.821344 · Cited by 202
Bufalin inhibits ovarian carcinoma via targeting mTOR/HIF‐α pathway
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Impact of Age-, Cancer- and Treatment-Driven Inflammation on T Cell Function and Immunotherapy
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Metadata
- Authors
- Cortez, A. J., Tudrej, P., Kujawa, K. A., & Lisowska, K. M.
- Venue
- Cancer Chemotherapy and Pharmacology
- Published
- 2017-12-16
- Volume
- 81
- Issue
- 1
- Pages
- 17-38
- ISSN
- 0344-5704 (ISSN-L)
- 1432-0843
- OpenAlex
- W2771491442
- Cited by
- 624
- References
- 102
- FWCI
- 47.57
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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