NALP Inflammasomes: a central role in innate immunity

The plant immune system

Jones, J. D. G., & Dangl, J. L. (2006) · Nature · doi:10.1038/nature05286 · Cited by 13,177

The Inflammasome

Martinon, F., Burns, K., & Tschopp, J. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00599-3 · Cited by 6,066

Gout-associated uric acid crystals activate the NALP3 inflammasome

Martinon, F., Pétrilli, V., Mayor, A., Tardivel, A., & Tschopp, J. (2006) · Nature · doi:10.1038/nature04516 · Cited by 5,326

The Danger Model: A Renewed Sense of Self

Matzinger, P. (2002) · Science · doi:10.1126/science.1071059 · Cited by 4,205

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

Sjöblom, T., Jones, S., Wood, L. D., Parsons, D. W., Lin, J., Barber, T. D., Mandelker, D. L., Leary, R. J., Ptak, J., Silliman, N., et al. (2006) · Science · doi:10.1126/science.1133427 · Cited by 3,161

Cryopyrin activates the inflammasome in response to toxins and ATP

Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature · doi:10.1038/nature04515 · Cited by 3,080

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

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NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder

Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N., & Tschopp, J. (2004) · Immunity · doi:10.1016/s1074-7613(04)00046-9 · Cited by 1,768

The leucine-rich repeat as a protein recognition motif

Kobe, B. (2001) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(01)00266-4 · Cited by 1,720

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., El-Deiry, W. S., Golstein, P., Green, D. R., et al. (2009) · Cell Death & Differentiation · doi:10.1038/cdd.2008.150 · Cited by 3,399

The Inflammasomes: Guardians of the Body

Martinon, F., Mayor, A., & Tschopp, J. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132715 · Cited by 2,436

Molecular mechanisms of necroptosis: an ordered cellular explosion

Vandenabeele, P., Galluzzi, L., Vanden Berghe, T., & Kroemer, G. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2970 · Cited by 2,382

Intracellular Toll-like Receptors

Blasius, A. L., & Beutler, B. (2010) · Immunity · doi:10.1016/j.immuni.2010.03.012 · Cited by 1,392

Immunogenic and tolerogenic cell death

Green, D. R., Ferguson, T., Zitvogel, L., & Kroemer, G. (2009) · Nature Reviews Immunology · doi:10.1038/nri2545 · Cited by 1,176

Innate immunity in the central nervous system

Ransohoff, R. M., & Brown, M. A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci58644 · Cited by 1,034

Inflammation and its role in age-related macular degeneration

Kauppinen, A., Paterno, J. J., Błasiak, J., Salminen, A., & Kaarniranta, K. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2147-8 · Cited by 683

RNA recognition and signal transduction by RIG‐I‐like receptors

Yoneyama, M., & Fujita, T. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00727.x · Cited by 595

Expansion and evolution of cell death programmes

Degterev, A., & Yuan, J. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2393 · Cited by 563

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

Bábelová, A., Moreth, K., Tsalastra, W., Zeng-Brouwers, J., Eickelberg, O., Young, M. F., Brückner, P., Pfeilschifter, J. M., Schaefer, R. M., Gröne, H., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.014266 · Cited by 484

Innate immunity in diabetes and diabetic nephropathy

Wada, J., & Makino, H. (2015) · Nature Reviews Nephrology · doi:10.1038/nrneph.2015.175 · Cited by 441

The multifunctional role of filaggrin in allergic skin disease

McAleer, M. A., & Irvine, A. D. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.12.668 · Cited by 426

Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis

Gasse, P., Riteau, N., Charron, S., Girre, S., Fick, L., Pétrilli, V., Tschopp, J., Lagente, V., Quesniaux, V. F. J., Ryffel, B., et al. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200808-1274oc · Cited by 410

The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences

Proell, M., Riedl, S. J., Fritz, J. H., Rojas, A. M., & Schwarzenbacher, R. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002119 · Cited by 403

Programmed necrosis: backup to and competitor with apoptosis in the immune system

Han, J., Zhong, C., & Zhang, D. (2011) · Nature Immunology · doi:10.1038/ni.2159 · Cited by 375

Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein-1a

Im, S., Yousef, L., Blaschitz, C., Liu, J. Z., Edwards, R. A., Young, S. G., Raffatellu, M., & Osborne, T. F. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.04.001 · Cited by 368

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

Schneider, M., Zimmermann, A. G., Roberts, R. A., Zhang, L., Swanson, K. V., Wen, H., Davis, B. K., Allen, I. C., Holl, E. K., Ye, Z., et al. (2012) · Nature Immunology · doi:10.1038/ni.2378 · Cited by 336

Pseudomonas aeruginosa activates caspase 1 through Ipaf

Miao, E. A., Ernst, R. K., Dors, M., Mao, D. P., & Aderem, A. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712183105 · Cited by 299

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

Bryan, N. B., Dorfleutner, A., Rojanasakul, Y., & Stehlik, C. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0802367 · Cited by 270

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes

Guarda, G., Dostert, C., Staehli, F., Cabalzar, K., Castillo, R., Tardivel, A., Schneider, P., & Tschopp, J. (2009) · Nature · doi:10.1038/nature08100 · Cited by 250

Mechanisms of uric acid crystal‐mediated autoinflammation

Martinon, F. (2009) · Immunological Reviews · doi:10.1111/j.0105-2896.2009.00860.x · Cited by 226

Necroptosis Is Active in Children With Inflammatory Bowel Disease and Contributes to Heighten Intestinal Inflammation

Pierdomenico, M., Negroni, A., Stronati, L., Vitali, R., Prete, E., Bertin, J., Gough, P. J., Aloi, M., & Cucchiara, S. (2013) · The American Journal of Gastroenterology · doi:10.1038/ajg.2013.403 · Cited by 223

NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1β processing via the NLRP1 inflammasome

Levandowski, C. B., Mailloux, C. M., Ferrara, T. M., Gowan, K., Ben, S., Jin, Y., McFann, K. K., Holland, P. J., Fain, P. R., Dinarello, C. A., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222808110 · Cited by 213

Scaffold proteins and immune-cell signalling

Shaw, A. S., & Filbert, E. L. (2008) · Nature reviews. Immunology · doi:10.1038/nri2473 · Cited by 215

Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region

Wang, C. M., Dixon, P. H., Decordova, S., Hodges, M., Sebire, N. J., Ozalp, S. S., Fallahian, M., Sensi, A., Ashrafi, F., Repiská, V., et al. (2009) · Journal of Medical Genetics · doi:10.1136/jmg.2008.064196 · Cited by 202

The inflammasome activating caspase 1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis

Artlett, C. M., Sassi‐Gaha, S., Rieger, J., Boesteanu, A. C., Feghali‐Bostwick, C. A., & Katsikis, P. D. (2011) · Arthritis & Rheumatism · doi:10.1002/art.30568 · Cited by 210

A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes

Magitta, N. F., Wolff, A. S. B., Johansson, S., Skinningsrud, B., Lie, B. A., Myhr, K.-M., Undlien, D. E., Joner, G., Njølstad, P. R., Kvien, T. K., et al. (2008) · Genes and Immunity · doi:10.1038/gene.2008.85 · Cited by 195

Induction of Inflammasome-dependent Pyroptosis by Carbon Black Nanoparticles

Reisetter, A. C., Stebounova, L. V., Baltrušaitis, J., Powers, L. S., Gupta, A. B., Grassian, V. H., & Monick, M. M. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.238519 · Cited by 197

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin‐1β

Bracey, N. A., Beck, P. L., Muruve, D. A., Hirota, S. A., Guo, J., Jabagi, H., Wright, J. R., MacDonald, J. A., Lees‐Miller, J. P., Roach, D., et al. (2012) · Experimental Physiology · doi:10.1113/expphysiol.2012.068338 · Cited by 192

Interleukin-1β (IL-1β) Processing Pathway

Weber, A., Wasiliew, P., & Kracht, M. (2010) · Science Signaling · doi:10.1126/scisignal.3105cm2 · Cited by 184

Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila

Case, C. L., Shin, S., & Roy, C. R. (2009) · Infection and Immunity · doi:10.1128/iai.01382-08 · Cited by 181

Evolution and functional divergence of NLRPgenes in mammalian reproductive systems

Tian, X., Pascal, G., & Monget, P. (2009) · BMC Evolutionary Biology · doi:10.1186/1471-2148-9-202 · Cited by 179

Multiple Nod-Like Receptors Activate Caspase 1 during Listeria monocytogenes Infection

Warren, S. E., Mao, D. P., Rodriguez, A. E., Miao, E. A., & Aderem, A. A. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.11.7558 · Cited by 182

Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes

Dai, X., Sayama, K., Tohyama, M., Shirakata, Y., Hanakawa, Y., Tokumaru, S., Yang, L., Hirakawa, S., & Hashimoto, K. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.12.006 · Cited by 175

Classification of Cell Death

Vural, D. F., Cebesoy, S., & Karakaş, M. F. (2013) · Journal of Entomology and Zoology Studies · Cited by 171

Genetic and Epigenetic Analysis of Recurrent Hydatidiform Mole

Hayward, B. E., Vos, M. D., Talati, N., Abdollahi, M. R., Taylor, G. R., Meyer, E., Williams, D., Maher, E. R., Setna, F., Nazir, K., et al. (2009) · Human Mutation · doi:10.1002/humu.20993 · Cited by 152

Reactive Oxygen Species, Oxidative Damage and Cell Death

Ghosh, N., Das, A., Chaffee, S. M., Roy, S., & Sen, C. K. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805417-8.00004-4 · Cited by 158

The mechanisms of action of vaccines containing aluminum adjuvants: an in vitro vs in vivo paradigm

Ghimire, T. R. (2015) · SpringerPlus · doi:10.1186/s40064-015-0972-0 · Cited by 156

Low and moderate doses of ionizing radiation up to 2 Gy modulate transmigration and chemotaxis of activated macrophages, provoke an anti-inflammatory cytokine milieu, but do not impact upon viability and phagocytic function

Wunderlich, R., Ernst, A., Rödel, F., Fietkau, R., Ott, O. J., Lauber, K., Frey, B., & Gaipl, U. S. (2014) · Clinical & Experimental Immunology · doi:10.1111/cei.12344 · Cited by 146

Detection of immune danger signals by NALP3

Martinon, F. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0607362 · Cited by 140

Metallothionein as an Anti-Inflammatory Mediator

Inoue, K., Takano, H., Shimada, A., & Satoh, M. (2009) · Mediators of Inflammation · doi:10.1155/2009/101659 · Cited by 132

Cellular Stress Response and Immune Signaling in Retinal Ischemia–Reperfusion Injury

Minhas, G., Sharma, J. N., & Khan, N. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00444 · Cited by 130

COPs and POPs: modulators of inflammasome activity

Stehlik, C., & Dorfleutner, A. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.12.7993 · Cited by 130

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function

Guey, B., Bodnar‐Wachtel, M., Manié, S. N., Tardivel, A., & Pétrilli, V. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1415756111 · Cited by 129

Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

Ganz, M. (2011) · World Journal of Gastroenterology · doi:10.3748/wjg.v17.i43.4772 · Cited by 122

Porphyromonas gingivalis activates NFκB and MAPK pathways in human oral epithelial cells

Groeger, S. E., Jarzina, F., Domann, E., & Meyle, J. (2017) · BMC Immunology · doi:10.1186/s12865-016-0185-5 · Cited by 121

Adipose Tissue–Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocyte Activation

Eljaafari, A., Robert, M., Chehimi, M., Chanon, S., Durand, C., Vial, G., Bendridi, N., Madec, A., Disse, E., Laville, M., et al. (2015) · Diabetes · doi:10.2337/db15-0162 · Cited by 113

Fluorofenidone attenuates pulmonary inflammation and fibrosis via inhibiting the activation of NALP 3 inflammasome and IL ‐1β/ IL ‐1R1/MyD88/ NF ‐κB pathway

Song, C., He, L., Zhang, J., Ma, H., Yuan, X., Hu, G., Tao, L., Zhang, J., & Meng, J. (2016) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12898 · Cited by 113

Viroporins and inflammasomes: A key to understand virus-induced inflammation

Farag, N. S., Breitinger, U., Breitinger, H., & Azizi, M. A. E. (2020) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2020.105738 · Cited by 106

The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond

Conforti‐Andreoni, C., Ricciardi‐Castagnoli, P., & Mortellaro, A. (2011) · Cellular and Molecular Immunology · doi:10.1038/cmi.2010.81 · Cited by 109

Cell death at the intestinal epithelial front line

Delgado, M. E., Grabinger, T., & Brunner, T. (2015) · FEBS Journal · doi:10.1111/febs.13575 · Cited by 107

Mast Cells, Histamine, and IL-6 Regulate the Selective Influx of Dendritic Cell Subsets into an Inflamed Lymph Node

Dawicki, W., Jawdat, D. M., Xu, N., & Marshall, J. S. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0803894 · Cited by 104

Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome

Wynosky-Dolfi, M. A., Snyder, A. G., Philip, N. H., Doonan, P. J., Poffenberger, M. C., Avizonis, D. Z., Zwack, E. E., Riblett, A. M., Hu, B., Strowig, T., et al. (2014) · The Journal of Experimental Medicine · doi:10.1084/jem.20130627 · Cited by 105

Toll-like receptors, the NLRP3 inflammasome, and interleukin-1β in the development and progression of type 1 diabetes

Grishman, E. K., White, P. C., & Savani, R. C. (2012) · Pediatric Research · doi:10.1038/pr.2012.24 · Cited by 104

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

Piippo, N., Korhonen, E., Hytti, M., Skottman, H., Kinnunen, K., Josifovska, N., Petrovski, G., Kaarniranta, K., & Kauppinen, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-25123-2 · Cited by 102

The N‐end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin

Xu, H., Shi, J., Gao, H., Liu, Y., Yang, Z., Shao, F., & Dong, N. (2019) · The EMBO Journal · doi:10.15252/embj.2019101996 · Cited by 105

The central role of calcium in the effects of cytokines on beta-cell function: Implications for type 1 and type 2 diabetes

Ramadan, J. W., Steiner, S. R., O’Neill, C. M., & Nunemaker, C. S. (2011) · Cell Calcium · doi:10.1016/j.ceca.2011.08.005 · Cited by 98

Low dose ionising radiation leads to a NF-κB dependent decreased secretion of active IL-1β by activated macrophages with a discontinuous dose-dependency

Lödermann, B., Wunderlich, R., Frey, S., Schorn, C., Stangl, S., Rödel, F., Keilholz, L., Fietkau, R., Gaipl, U. S., & Frey, B. (2012) · International Journal of Radiation Biology · doi:10.3109/09553002.2012.689464 · Cited by 100

Inhibition of the Type I Interferon Antiviral Response During Arenavirus Infection

Borrow, P., Martínez‐Sobrido, L., & de la Torre, J. C. (2010) · Viruses · doi:10.3390/v2112443 · Cited by 89

Targeting solid tumors with non‐pathogenic obligate anaerobic bacteria

Taniguchi, S., Fujimori, M., Sasaki, T., Tsutsui, H., Shimatani, Y., Seki, K., & Amano, J. (2010) · Cancer Science · doi:10.1111/j.1349-7006.2010.01628.x · Cited by 87

Necroptosis and its role in infectious diseases

Xia, X., Lei, L., Wang, S., Hu, J., & Zhang, G. (2020) · APOPTOSIS · doi:10.1007/s10495-019-01589-x · Cited by 83

The genetics of gestational trophoblastic disease: a rare complication of pregnancy

Hoffner, L., & Surti, U. (2012) · Cancer Genetics · doi:10.1016/j.cancergen.2012.01.004 · Cited by 86

Desirable cell death during anticancer chemotherapy

Locher, C., Conforti, R., Aymeric, L., Ma, Y., Yamazaki, T., Rusakiewicz, S., Tesnière, A., Ghiringhelli, F., Apétoh, L., Morel, Y., et al. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05763.x · Cited by 84

Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity

Bednash, J. S., Weathington, N. M., Londino, J. D., Rojas, M. M., Gulick, D. L., Fort, R., Han, S., McKelvey, A. C., Chen, B. B., & Mallampalli, R. K. (2017) · Nature Communications · doi:10.1038/ncomms15203 · Cited by 85

How the study of children with rheumatic diseases identified interferon‐α and interleukin‐1 as novel therapeutic targets

Pascual, V., Allantaz, F., Patel, P., Palucka, K., Chaussabel, D., & Banchereau, J. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00643.x · Cited by 78

Insights into the diversity of NOD-like receptors: Identification and expression analysis of NLRC3, NLRC5 and NLRX1 in rainbow trout

Álvarez, C., Ramírez-Cepeda, F., Santana, P., Torres, E., Cortés, J., Guzmán, F., Schmitt, P., & Mercado, L. A. (2017) · Molecular Immunology · doi:10.1016/j.molimm.2017.03.010 · Cited by 75

New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors

Corriden, R., & Insel, P. A. (2012) · Purinergic Signalling · doi:10.1007/s11302-012-9311-x · Cited by 78

Digital gene expression analysis in hemocytes of the white shrimp Litopenaeus vannamei in response to low salinity stress

Zhao, Q., Pan, L., Ren, Q., & Hu, D. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.11.020 · Cited by 75

Co-Regulation of NF-κB and Inflammasome-Mediated Inflammatory Responses by Myxoma Virus Pyrin Domain-Containing Protein M013

Rahman, M. M., Mohamed, M. R., Kim, M., Smallwood, S. E., & McFadden, G. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000635 · Cited by 70

Heat shock proteins and immunity: Application of hyperthermia for immunomodulation

Torigoe, T., Tamura, Y., & Sato, N. (2009) · International Journal of Hyperthermia · doi:10.3109/02656730903315831 · Cited by 71

Necroptotic signaling in adaptive and innate immunity

Lu, J. V., Chen, H. C., & Walsh, C. M. (2014) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2014.07.003 · Cited by 71

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability

Hadadi, É., Zhang, B., Baidžajevas, K., Yusof, N., Puan, K. J., Ong, S., Yeap, W. H., Rötzschke, O., Kiss‐Toth, E., Wilson, H. L., et al. (2016) · Scientific Reports · doi:10.1038/srep39035 · Cited by 74

Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention

Furlan, S. N., Watkins, B. K., Tkachev, V., Flynn, R. P., Cooley, S., Ramakrishnan, S., Singh, K., Giver, C., Hamby, K., Stempora, L., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aad3231 · Cited by 65

Chronic mucocutaneous candidiasis and congenital susceptibility to Candida

Glocker, E. O., & Grimbacher, B. (2010) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e32833fd74f · Cited by 64

Porphyromonas gingivalis attenuates ATP-mediated inflammasome activation and HMGB1 release through expression of a nucleoside-diphosphate kinase

Johnson, L., Atanasova, K. R., Bui, P. Q., Lee, J., Hung, S.-C., Yilmaz, Ö., & Ojcius, D. M. (2015) · Microbes and Infection · doi:10.1016/j.micinf.2015.03.010 · Cited by 63

Association Between Psoriasis and Vitiligo: A Systematic Review and Meta-Analysis

Yen, H., & Chi, C. (2018) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-0394-1 · Cited by 63

Role of NF-κB activation in intestinal immune homeostasis

Wullaert, A. (2009) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2009.08.007 · Cited by 62

Temporal Interleukin-1β Secretion from Primary Human Peripheral Blood Monocytes by P2X7-independent and P2X7-dependent Mechanisms

Ward, J. R., West, P., Ariaans, M. P., Parker, L. C., Francis, S., Crossman, D. C., Sabroe, I., & Wilson, H. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.072793 · Cited by 62

Elevated Expression of the NLRP3 Inflammasome and Its Correlation with Disease Activity in Adult-onset Still Disease

Hsieh, C., Chen, Y., Lin, C., Tang, K., Chen, H., Hung, W., Lai, K., & Chen, D. (2017) · The Journal of Rheumatology · doi:10.3899/jrheum.161354 · Cited by 61

Viroporins: Structure, function, and their role in the life cycle of SARS-CoV-2

Breitinger, U., Farag, N. S., Sticht, H., & Breitinger, H. (2022) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2022.106185 · Cited by 60

The subcortical maternal complex protein Nlrp4f is involved in cytoplasmic lattice formation and organelle distribution

Qin, D., Gao, Z., Xiao, Y., Zhang, X., Ma, H., Yu, X., Nie, X., Fan, N., Wang, X., Ouyang, Y., et al. (2019) · Development · doi:10.1242/dev.183616 · Cited by 56

Polyphenols, flavonoids and inflammasomes: the role of cigarette smoke in COPD

Fu, Y., Kang, N., Yu, Y., Mi, Y., Guo, J., Wu, J., & Weng, C. (2022) · European Respiratory Review · doi:10.1183/16000617.0028-2022 · Cited by 54

Artemisinin suppresses myocardial ischemia–reperfusion injury via NLRP3 inflammasome mechanism

Wang, F., Gao, Q., Yang, J., Wang, C., Cao, J., Sun, J., Fan, Z., & Fu, L. (2020) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-03842-3 · Cited by 54

Epidermal keratinocytes sense ds RNA via the NLRP 3 inflammasome, mediating interleukin ( IL )‐1β and IL ‐18 release

Dai, X., Tohyama, M., Murakami, M., & Sayama, K. (2017) · Experimental Dermatology · doi:10.1111/exd.13334 · Cited by 50

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Accelerated Ovarian Aging in the Absence of the Transcription Regulator TAF4B in Mice1

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Cross-talk of human gut with bifidobacteria

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High-Density Lipoproteins Decrease Proinflammatory Activity and Modulate the Innate Immune Response

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Heme Induces IL-1β Secretion Through Activating NLRP3 in Kidney Inflammation

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ASC Apoptosis-associated speck-like protein con-

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NALPs: a novel protein family involved in inflammation

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Pyrin Domain (PYD)-containing Inflammasome in Innate Immunity

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