The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Molecular basis of Staphylococcus epidermidis infections
Open accessAbstract
Staphylococcus epidermidis is the most important member of the coagulase-negative staphylococci and one of the most abundant colonizers of human skin. While for a long time regarded as innocuous, it has been identified as the most frequent cause of device-related infections occurring in the hospital setting and is therefore now recognized as an important opportunistic pathogen. S. epidermidis produces a series of molecules that provide protection from host defenses. Specifically, many proteins and exopolymers, such as the exopolysaccharide PIA, contribute to biofilm formation and inhibit phagocytosis and the activity of human antimicrobial peptides. Furthermore, recent research has identified a family of pro-inflammatory peptides in S. epidermidis, the phenol-soluble modulins (PSMs), which have multiple functions in immune evasion and biofilm development, and may be cytolytic. However, in accordance with the relatively benign relationship that S. epidermidis has with its host, production of aggressive members of the PSM family is kept at a low level. Interestingly, in contrast to S. aureus with its large arsenal of toxins developed for causing infection in the human host, most if not all “virulence factors” of S. epidermidis appear to have original functions in the commensal lifestyle of this bacterium.
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Cites
Bacterial Biofilms: A Common Cause of Persistent Infections
Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167
The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm
Davies, D. G., Parsek, M. R., Pearson, J. P., Iglewski, B. H., Costerton, J. W., & Greenberg, E. P. (1998) · Science · doi:10.1126/science.280.5361.295 · Cited by 3,396
Nasal Carriage as a Source of Staphylococcus aureus Bacteremia
von Eiff, C., Becker, K., Machka, K., Stammer, H., & Peters, G. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440102 · Cited by 1,984
Fruiting body formation by Bacillus subtilis
Branda, S. S., González-Pastor, J. E., Ben-Yehuda, S., Losick, R., & Kolter, R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.191384198 · Cited by 1,129
Staphylococcus aureus Sortase, an Enzyme that Anchors Surface Proteins to the Cell Wall
Mazmanian, S. K., Liu, G., Ton-That, H., & Schneewind, O. (1999) · Science · doi:10.1126/science.285.5428.760 · Cited by 1,053
Wang, R., Braughton, K. R., Kretschmer, D., Bach, T.-H. L., Queck, S. Y., Li, M., Kennedy, A. D., Dorward, D. W., Klebanoff, S. J., Peschel, A., et al. (2007) · Nature Medicine · doi:10.1038/nm1656 · Cited by 1,046
Self-citationIwase, T., Uehara, Y., Shinji, H., Tajima, A., Seo, H., Takada, K., Agata, T., & Mizunoe, Y. (2010) · Nature · doi:10.1038/nature09074 · Cited by 991
Contemporary Clinical Profile and Outcome of Prosthetic Valve Endocarditis
Wang, A. (2007) · JAMA · doi:10.1001/jama.297.12.1354 · Cited by 703
Heilmann, C., Hussain, M., Peters, G., & Götz, F. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.4101774.x · Cited by 700
Bacterial Competition for Human Nasal Cavity Colonization: Role of Staphylococcal agr Alleles
Lina, G., Boutite, F., Tristan, A., Bes, M., Etienne, J., & Vandenesch, F. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.1.18-23.2003 · Cited by 381
Cited by
Arciola, C. R., Campoccia, D., Speziale, P., Montanaro, L., & Costerton, J. W. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.05.031 · Cited by 1,047
Prevention of Intravascular Catheter-Related Infections
(2021) · Indian Journal of Continuing Nursing Education · doi:10.4103/2230-7354.320831 · Cited by 855
Structure and function of the human skin microbiome
Schommer, N. N., & Gallo, R. L. (2013) · Trends in Microbiology · doi:10.1016/j.tim.2013.10.001 · Cited by 532
Carvalhais, V., Delgado-Rastrollo, M., Melo, L. D. R., & Cerca, N. (2013) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2013.08.010 · Cited by 20
Metadata
- Authors
- Otto, M.
- Venue
- Seminars in Immunopathology
- Published
- 2011-11-19
- Volume
- 34
- Issue
- 2
- Pages
- 201-214
- ISSN
- 1863-2297 (ISSN-L)
- 1863-2300
- OpenAlex
- W2012539366
- Cited by
- 265
- References
- 12
- FWCI
- 12.21
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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