Dietary intake of advanced glycation end products (AGEs) and changes in body weight in European adults
Open accessAbstract
Purpose Advanced glycation end products (AGEs) can be formed in foods by the reaction of reducing sugars with proteins, and have been shown to induce insulin resistance and obesity in experimental studies. We examined the association between dietary AGEs intake and changes in body weight in adults over an average of 5 years of follow-up.Methods A total of 255,170 participants aged 25-70 years were recruited in ten European countries (1992-2000) in the PANACEA study (Physical Activity, Nutrition, Alcohol, Cessation of smoking, Eating out of home in relation to Anthropometry), a sub-cohort of the EPIC (European Prospective Investigation into Cancer and Nutrition). Body weight was measured at recruitment and self-reported between 2 and 11 years later depending on the study center. A reference database for AGEs was used containing UPLC-MS/MS-measured N ε-(carboxymethyl)-lysine (CML), N ε-(1-carboxyethyl)-lysine (CEL), and N δ-(5-hydro-5-methyl-4-imidazolon-2-yl)-ornithine (MG-H1) in 200 common European foods. This reference database was matched to foods and decomposed recipes obtained from country-specific validated dietary questionnaires in EPIC and intake levels of CEL, CML, and MG-H1 were estimated. Associations between dietary AGEs intake and body weight change were estimated separately for each of the three AGEs using multilevel mixed linear regression models with center as random effect and dietary AGEs intake and relevant confounders as fixed effects.Results A one-SD increment in CEL intake was associated with 0.111 kg (95% CI 0.087-0.135) additional weight gain over 5 years. The corresponding additional weight gain for CML and MG-H1 was 0.065 kg (0.041-0.089) and 0.034 kg (0.012, 0.057), respectively. The top six food groups contributing to AGEs intake, with varying proportions across the AGEs, were cereals/cereal products, meat/processed meat, cakes/biscuits, dairy, sugar and confectionary, and fish/shellfish.Conclusion In this study of European adults, higher intakes of AGEs were associated with marginally greater weight gain over an average of 5 years of follow-up.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Consumption of dietary AGEs does not necessarily increase obesity based on its marginal association with increased body weight gain.
“although consumption of dietary AGEs does not necessarily increase obesity based on its marginal association with increased body weight gain67,76.”
From Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury (2021) · cites this paper as [76]
Dietary and endogenous AGEs and the AGE-RAGE interaction can promote oxidative stress and inflammation, contributing to accelerated progression of obesity-related complications.
“Dietary and endogenous AGEs and the AGE-RAGE interaction can promote oxidative stress and inflammation, contributing to the accelerated progression of obesity-related complications such as elevated serum AGEs, insulin resistance, AGE accumulation, and elevated proinflammatory cytokines in adipose tissues67,76, although consumption of dietary AGEs does not necessarily increase obesity based on its”
From Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury (2021) · cites this paper as [76]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763 · see citing works
Gupta, A., & Uribarri, J. (2016) · Hormone Research in Paediatrics · doi:10.1159/000444053 · Cited by 4,019 · see citing works
The Epidemiology of Obesity: A Big Picture
Hruby, A., & Hu, F. B. (2014) · PharmacoEconomics · doi:10.1007/s40273-014-0243-x · Cited by 3,006 · see citing works
Hall, K. D., Ayuketah, A., Brychta, R., Cai, H., Cassimatis, T., Chen, K. Y., Chung, S. T., Costa, E., Courville, A., Darcey, V., et al. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.05.008 · Cited by 1,971 · see citing works
Riboli, E., Hunt, K., Slimani, N., Ferrari, P., Norat, T., Fahey, M., Charrondière, U., Hémon, B., Casagrande, C., Vignat, J., et al. (2002) · Public Health Nutrition · doi:10.1079/phn2002394 · Cited by 1,866 · see citing works
Self-citationBlack, A. (2000) · International Journal of Obesity · doi:10.1038/sj.ijo.0801376 · Cited by 1,490 · see citing works
Validity of self-reported height and weight in 4808 EPIC–Oxford participants
Spencer, E. A., Appleby, P. N., Davey, G. K., & Key, T. J. (2002) · Public Health Nutrition · doi:10.1079/phn2001322 · Cited by 1,082 · see citing works
Global status report on noncommunicable diseases
Chan, M. (2010) · Cited by 1,065 · see citing works
Ríboli, E. (1997) · International Journal of Epidemiology · doi:10.1093/ije/26.suppl_1.s6 · Cited by 944 · see citing works
Dombrowski, S. U., Knittle, K., Avenell, A., Araujo-Soares, V., & Sniehotta, F. F. (2014) · BMJ · doi:10.1136/bmj.g2646 · Cited by 816 · see citing works
Koschinsky, T., He, C.-J., Mitsuhashi, T., Bucala, R., Liu, C., Buenting, C., Heitmann, K., & Vlassara, H. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.12.6474 · Cited by 792 · see citing works
Advanced glycation endproducts in food and their effects on health
Poulsen, M. W., Hedegaard, R. V., Andersen, J. M., de Courten, B., Bügel, S., Nielsen, J., Skibsted, L. H., & Dragsted, L. O. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.06.052 · Cited by 751 · see citing works
Advanced glycoxidation end products in commonly consumed foods
Goldberg, T., Cai, W., Peppa, M., Dardaine, V., Baliga, B. S., Uribarri, J., & Vlassara, H. (2004) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2004.05.214 · Cited by 744 · see citing works
Douketis, J. D., Macie, C., Thabane, L., & Williamson, D. F. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0802982 · Cited by 665 · see citing works
Naska, A., Lagiou, A., & Λάγιου, Π. (2017) · F1000Research · doi:10.12688/f1000research.10703.1 · Cited by 500 · see citing works
Slimani, N., Deharveng, G., Unwin, I. D., Southgate, D. A. T., Vignat, J., Skeie, G., Salvini, S., Parpinel, M. T., Møller, A., Ireland-Ripert, J., et al. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602679 · Cited by 362 · see citing works
Self-citationBuckland, G., Gonzalez, C. A., Agudo, A., Vilardell, M., Berenguer, A., Amiano, P., Ardanaz, E., Arriola, L., Barricarte, A., Basterretxea, M., et al. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp282 · Cited by 344 · see citing works
Self-citationScheijen, J. L. J. M., Clevers, E., Engelen, L., Dagnelie, P. C., Brouns, F., Stehouwer, C. D. A., & Schalkwijk, C. G. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2015.06.049 · Cited by 343 · see citing works
Self-citationCai, W., Ramdas, M., Zhu, L., Chen, X., Striker, G. E., & Vlassara, H. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1205847109 · Cited by 330 · see citing works
New obesity classification criteria as a tool for bariatric surgery indication
LORENZO, A. D. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i2.681 · Cited by 312 · see citing works
(2008) · doi:10.1093/acprof:oso/9780195312911.001.0001 · Cited by 265 · see citing works
Advanced glycation End-products (AGEs): an emerging concern for processed food industries
Sharma, C., Kaur, A., Thind, S. S., Singh, B., & Raina, S. (2015) · Journal of Food Science and Technology · doi:10.1007/s13197-015-1851-y · Cited by 254 · see citing works
Birlouez‐Aragon, I., Saavedra, G., Tessier, F. J., Galinier, A., Ameur, L. A., Lacoste, F., Niamba, C.-N., Alt, N., Somoza, V., & Lecerf, J. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28737 · Cited by 246 · see citing works
Meat consumption and prospective weight change in participants of the EPIC-PANACEA study
Vergnaud, A., Norat, T., Romaguera, D., Mouw, T., May, A. M., Travier, N., Luan, J., Wareham, N. J., Slimani, N., Rinaldi, S., et al. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28713 · Cited by 227 · see citing works
Self-citationRomaguera, D., Norat, T., Vergnaud, A., Mouw, T., May, A. M., Agudo, A., Buckland, G., Slimani, N., Rinaldi, S., Couto, E., et al. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29482 · Cited by 227 · see citing works
Self-citationElevated Levels of the Reactive Metabolite Methylglyoxal Recapitulate Progression of Type 2 Diabetes
Moraru, A., Wiederstein, J. L., Pfaff, D. H., Fleming, T. H., Miller, A. K., Nawroth, P. P., & Teleman, A. A. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.02.003 · Cited by 170 · see citing works
Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity
Gaens, K. H., Stehouwer, C. D., & Schalkwijk, C. G. (2013) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32835aea13 · Cited by 166 · see citing works
Self-citationScheijen, J. L. J. M., Hanssen, N. M. J., van Greevenbroek, M. M. J., Kallen, C., Feskens, E. J. M., Stehouwer, C. D. A., & Schalkwijk, C. G. (2017) · Clinical Nutrition · doi:10.1016/j.clnu.2017.03.019 · Cited by 164 · see citing works
Self-citationde Courten, B. V., de Courten, M., Soldatos, G., Dougherty, S. L., Straznicky, N. E., Schlaich, M. P., Sourris, K. C., Chand, V., Scheijen, J. L. J. M., Kingwell, B. A., et al. (2016) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.125427 · Cited by 139 · see citing works
Self-citationDietary sugars, not lipids, drive hypothalamic inflammation
Gao, Y., Bielohuby, M., Fleming, T., Grabner, G. F., Foppen, E., Bernhard, W., Guzmán-Ruiz, M., Layritz, C., Legutko, B., Zinser, E., et al. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.06.008 · Cited by 131 · see citing works
Insulin translates unfavourable lifestyle into obesity
Kolb, H., Stümvoll, M., Kramer, W., Kempf, K., & Martin, S. (2018) · BMC Medicine · doi:10.1186/s12916-018-1225-1 · Cited by 115 · see citing works
Skeie, G., Borch, K. B., Mode, N. A., & Henningsen, M. (2015) · Clinical Epidemiology · doi:10.2147/clep.s83839 · Cited by 114 · see citing works
Self-citationVergnaud, A., Norat, T., Romaguera, D., Mouw, T., May, A. M., Romieu, I., Freisling, H., Slimani, N., Boutron‐Ruault, M., Clavel‐Chapelon, F., et al. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.019968 · Cited by 96 · see citing works
Self-citationCrino, M., Sacks, G., Vandevijvere, S., Swinburn, B. A., & Neal, B. C. (2015) · Current Obesity Reports · doi:10.1007/s13679-014-0134-7 · Cited by 90 · see citing works
Smith, J. D., Hou, T., Hu, F. B., Rimm, E. B., Spiegelman, D. L., Willett, W. C., & Mozaffarian, D. (2015) · Journal of Nutrition · doi:10.3945/jn.115.214171 · Cited by 78 · see citing works
Freisling, H., Noh, H., Slimani, N., Chajès, V., May, A. M., Peeters, P. H. M., Weiderpass, E., Cross, A. J., Skeie, G., Jenab, M., et al. (2017) · European Journal of Nutrition · doi:10.1007/s00394-017-1513-0 · Cited by 75 · see citing works
Self-citationFreisling, H., van Bakel, M. M. E., Biessy, C., May, A. M., Byrnes, G. B., Norat, T., Rinaldi, S., de Magistris, M. S., Grioni, S., Bueno-de-Mesquita, H. B., et al. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511003564 · Cited by 74 · see citing works
Self-citationDiamanti‐Kandarakis, E., Palimeri, S., & Palioura, E. (2015) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s63089 · Cited by 73 · see citing works
Does Hypothalamic Inflammation Cause Obesity?
Wisse, B. E., & Schwartz, M. W. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.09.003 · Cited by 62 · see citing works
Advanced Glycation End Products Induce Obesity and Hepatosteatosis in CD-1 Wild-Type Mice
Sayej, W. N., Knight, P. R., Guo, W. A., Mullan, B., Ohtake, P. J., Davidson, B. A., Khan, A. R., Baker, R. D., & Baker, S. S. (2016) · BioMed Research International · doi:10.1155/2016/7867852 · Cited by 57 · see citing works
Rajan, B. S., Manivasagam, S., Dhanusu, S., Chandrasekar, N., Krishna, K., Kalaiarasu, L. P., Babu, A. A., & Vellaichamy, E. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.02.016 · Cited by 46 · see citing works
Park, J. Y., Mitrou, P. N., Keogh, R. H., Luben, R., Wareham, N. J., & Khaw, K. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.61 · Cited by 41 · see citing works
Forbes, J. M., Sourris, K. C., de Courten, M., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D. A., Coughlan, M. T., Schlaich, M. P., Soldatos, G., et al. (2013) · Amino Acids · doi:10.1007/s00726-013-1542-9 · Cited by 34 · see citing works
Gottschald, M., Knüppel, S., Boeing, H., & Buijsse, B. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.131 · Cited by 22 · see citing works
Self-citationDietary Advanced Glycation End-Products: Molecular mechanisms and Preventive Tools
Piperi, C. (2017) · Current Nutrition Reports · doi:10.1007/s13668-017-0188-8 · Cited by 10 · see citing works
Electrophoretic Analysis of Polypeptides of Plasma Membranes from Bovine Pituitary Gland
Lemay, A., & Labrie, F. (1974) · Canadian Journal of Biochemistry · doi:10.1139/o74-089 · Cited by 5 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Rungratanawanich, W., Qu, Y., Wang, X., Essa, M. M., & Song, B.-J. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00561-7 · Cited by 411 · see citing works
Córdova, R., Kliemann, N., Huybrechts, I., Rauber, F., Vamos, E. P., Levy, R. B., Wagner, K., Viallon, V., Casagrande, C., Nicolas, G., et al. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.08.009 · Cited by 133 · see citing works
Self-citationPal, R., & Bhadada, S. K. (2023) · Bone · doi:10.1016/j.bone.2023.116884 · Cited by 91 · see citing works
van Dongen, K. C. W., Linkens, A. M. A., Wetzels, S., Wouters, K., Vanmierlo, T., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., de Vos, W. M., Belzer, C., & Schalkwijk, C. G. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110547 · Cited by 84 · see citing works
Self-citationDietary glycation compounds – implications for human health
Hellwig, M., Diel, P. R., Eisenbrand, G., Grune, T., Guth, S., Henle, T., Humpf, H., Joost, H., Marko, D., Raupbach, J., et al. (2024) · Critical Reviews in Toxicology · doi:10.1080/10408444.2024.2362985 · Cited by 79 · see citing works
Ibsen, D. B., Steur, M., Imamura, F., Overvad, K., Schulze, M. B., Bendinelli, B., Guevara, M., Agudo, A., Amiano, P., Aune, D., et al. (2020) · Diabetes Care · doi:10.2337/dc20-1038 · Cited by 60 · see citing works
Self-citationMaasen, K., Eussen, S. J. P. M., Scheijen, J. L. J. M., Kallen, C., Dagnelie, P. C., Opperhuizen, A., Stehouwer, C. D. A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab329 · Cited by 41 · see citing works
Self-citationSohouli, M. H., Sharifi‐Zahabi, E., Lari, A., Fatahi, S., & Shidfar, F. (2020) · Scientific Reports · doi:10.1038/s41598-020-79216-y · Cited by 28 · see citing works
Biscuit Contaminants, Their Sources and Mitigation Strategies: A Review
Pasqualone, A., Haider, N. N., Summo, C., Coldea, T. E., George, S. S., & Altemimi, A. B. (2021) · Foods · doi:10.3390/foods10112751 · Cited by 28 · see citing works
Cao, C., Tang, M., Zhao, N., Dong, S., & Wu, H. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104636 · Cited by 26 · see citing works
Adeshara, K. A., Bangar, N. S., Diwan, A. G., & Tupe, R. S. (2022) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2022.102441 · Cited by 26 · see citing works
Mayén, A., Aglago, E. K., Knaze, V., Córdova, R., Schalkwijk, C. G., Wagner, K., Aleksandrova, K., Fedirko, V., Keski‐Rahkonen, P., Leitzmann, M. F., et al. (2021) · International Journal of Cancer · doi:10.1002/ijc.33612 · Cited by 25 · see citing works
Self-citationJalil, A. T., Alameri, A. A., Doewes, R. I., El‐Sehrawy, A. A. M. A., Ahmad, I., Ramaiah, P., Kadhim, M. M., Kzar, H. H., Sivaraman, R., Romero‐Parra, R. M., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.966590 · Cited by 24 · see citing works
Aglago, E. K., Mayén, A., Knaze, V., Freisling, H., Fedirko, V., Hughes, D. J., Jiao, L., Eriksen, A. K., Tjønneland, A. M., Boutron‐Ruault, M., et al. (2021) · Nutrients · doi:10.3390/nu13093132 · Cited by 20 · see citing works
Self-citationLinkens, A. M. A., van Best, N., Niessen, P., Wijckmans, N. E. G., de Goei, E. E. C., Scheijen, J. L. J. M., DONGEN, M. C. J. M. V., van Gool, C. J., de Vos, W. M., Houben, A. J. H. M., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105328 · Cited by 20 · see citing works
Self-citationSenatus, L. M., MacLean, M., Arivazhagan, L., Egaña-Gorroño, L., López‐Díez, R., Manigrasso, M. B., Ruiz, H. H., Vásquez, C., Wilson, R. A., Shekhtman, A. G., et al. (2021) · Immunometabolism · doi:10.20900/immunometab20210024 · Cited by 20 · see citing works
Mao, Z., Aglago, E. K., Zhao, Z., Schalkwijk, C. G., Jiao, L., Freisling, H., Weiderpass, E., Hughes, D. J., Eriksen, A. K., Tjønneland, A. M., et al. (2021) · Nutrients · doi:10.3390/nu13124435 · Cited by 18 · see citing works
Self-citationAcrylamide and Advanced Glycation End Products in Frying Food: Formation, Effects, and Harmfulness
Rasool, A., Luo, X., Zhang, Q., Jia, C., Zhao, S., Liu, R., Rong, J., Zhou, G., Wang, B., Kuai, J., et al. (2025) · Foods · doi:10.3390/foods14193313 · Cited by 17 · see citing works
Linkens, A. M. A., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., Henry, R. M. A., de Galan, B. E., Stehouwer, C. D. A., et al. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab302 · Cited by 17 · see citing works
Self-citationAglago, E. K., Schalkwijk, C. G., Freisling, H., Fedirko, V., Hughes, D. J., Jiao, L., Dahm, C. C., Olsen, A., Tjønneland, A. M., Katzke, V. A., et al. (2021) · Carcinogenesis · doi:10.1093/carcin/bgab026 · Cited by 15 · see citing works
Self-citationKim, Y. (2023) · Nutrients · doi:10.3390/nu15082002 · Cited by 14 · see citing works
Dietary diversity and nutritional status of adolescents in Lagos, Nigeria
Olatona, F. A., Ogide, P. I., Abikoye, E. T., Ilesanmi, O. T., & Nnoaham, K. E. (2023) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_1783_22 · Cited by 20 · see citing works
Nagata, C., Wada, K., Yamakawa, M., Nakashima, Y., Koda, S., Uji, T., & Oba, S. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa230 · Cited by 13 · see citing works
Linkens, A. M. A., Eussen, S. J. P. M., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Reesink, K. D., Dagnelie, P. C., Henry, R. M. A., van Greevenbroek, M. M. J., Wesselius, A., et al. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab097 · Cited by 12 · see citing works
Self-citationZhang, Y., Jiang, F., Liu, D., Li, X., Ma, Z., Zhang, Y., Ma, A., Qin, L., Chen, G.-C., & Wan, Z. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.08.006 · Cited by 11 · see citing works
Zhu, R., Fogelholm, M., Jalo, E., Poppitt, S. D., Silvestre, M. P., Møller, G., Huttunen‐Lenz, M., Stratton, G., Sundvall, J., Macdonald, I. A., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.02.002 · Cited by 14 · see citing works
Koyama, A. K., Pavkov, M. E., Wu, Y., & Siegel, K. R. (2022) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2022.02.008 · Cited by 11 · see citing works
Kahleová, H., Znayenko‐Miller, T., Motoa, G., Eng, E. M., Prevost, A., Uribarri, J., Holubkov, R., & Barnard, N. D. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1426642 · Cited by 10 · see citing works
Córdova, R., Mayén, A., Knaze, V., Aglago, E. K., Schalkwijk, C. G., Wagner, K., Overvad, K., Tjønneland, A. M., Kyrø, C., Katzke, V. A., et al. (2022) · 癌症:英文版 · doi:10.1002/cac2.12343 · Cited by 10 · see citing works
Self-citationFood obesogens as emerging metabolic disruptors; A toxicological insight
Ravichandran, G., Kumar, D., Arunachalam, A., & Thilagar, S. (2021) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2021.106042 · Cited by 10 · see citing works
Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.04.011 · Cited by 8 · see citing works
Self-citationMayén, A., Maasen, K., Hana, C. A., Knaze, V., Scheijen, J. L. J. M., Eussen, S. J. P. M., Vangrieken, P., Debras, C., Blanco, J., Dahm, C. C., et al. (2025) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwaf060 · Cited by 8 · see citing works
Self-citationLast Five Years Development In Food Safety Perception of n-Carboxymethyl Lysine
Golchinfar, Z., Farshi, P., Mahmoudzadeh, M., Mohammadi, M., Tabibiazar, M., & Smith, J. S. (2021) · Food Reviews International · doi:10.1080/87559129.2021.2011909 · Cited by 6 · see citing works
Arena, S., Pascale, S. D., Ciaravolo, V., Monroy, M. M., Gouw, J. W., Stahl, B., Bäuerl, C., Collado, M. C., Filippo, C. D., Scaloni, A., et al. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.141265 · Cited by 5 · see citing works
Xu, Y., Huang, M., Chen, Y., Yu, L., Wu, M., Kang, S., Lin, Q., Zhang, Q., Han, L., Lin, H., et al. (2024) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2024.116035 · Cited by 5 · see citing works
Mendes, N. P., Cândido, F. G., Valente, F. X., Pelúzio, M. D. C. G., Juvanhol, L. L., & Alfenas, R. D. C. G. (2024) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2024.03.011 · Cited by 5 · see citing works
Tong, L., Zhang, X., Chen, J., He, H., Zhang, W., Wan, Z., & Zhang, H. (2025) · Scientific Reports · doi:10.1038/s41598-025-85361-z · Cited by 5 · see citing works
Matafome, P. N. (2020) · Diabetology · doi:10.3390/diabetology1010004 · Cited by 5 · see citing works
Dietary Patterns, Nutritional Knowledge and Status of Adolescents in Lagos, Nigeria.Preprint
Olatona, F. A., Ogide, P. I., Abikoye, E. T., Ilesanmi, O. T., & Nnoaham, K. E. (2020) · Research Square · doi:10.21203/rs.3.rs-18023/v1 · Cited by 5 · see citing works
Zhang, H., Mo, L., Chen, X., Li, M., Li, M., Xu, Y., Zeng, M., He, Z., Shen, Q. W., Chen, J., et al. (2023) · Food Science and Human Wellness · doi:10.26599/fshw.2022.9250240 · Cited by 4 · see citing works
Sex-specific differences of advanced glycation end products in diabetes
Hellwig, M., Decker, J., Roma, L. P., Schunk, S. J., Ampofo, E., & Rother, S. (2025) · Nutrition and Diabetes · doi:10.1038/s41387-025-00379-6 · Cited by 4 · see citing works
Russo, M. D., Sirangelo, I., Lauria, F., Formisano, A., Iannuzzi, C., Hebestreit, A., Pala, V. M., Siani, A., & Russo, P. (2024) · Nutrients · doi:10.3390/nu16121831 · Cited by 4 · see citing works
Wu, Y., Wu, Y.-T., Zhang, Z., Cai, J., Zong, M.-H., Li, L., Zhang, X., Wu, H.-C., & Li, B. (2023) · ACS Food Science & Technology · doi:10.1021/acsfoodscitech.3c00176 · Cited by 4 · see citing works
Tate, D. E., Tanprasertsuk, J., Tarr, D. S., Shmalberg, J. W., & Honaker, R. W. (2026) · Journal of Animal Science · doi:10.1093/jas/skag206 · Cited by 4 · see citing works
Debras, C., Córdova, R., Mayén, A., Maasen, K., Knaze, V., Eussen, S. J. P. M., Schalkwijk, C. G., Huybrechts, I., Tjønneland, A. M., Halkjær, J., et al. (2024) · British Journal Of Nutrition · doi:10.1017/s0007114524000503 · Cited by 3 · see citing works
Self-citationBai, M. R., Vedantham, S., Shobana, S., Nagarajan, L. P., Gayathri, R., Gunasekaran, G., Gayathri, N., Chandrashekaran, A., Gokulakrishnan, K., Sandhya, N., et al. (2021) · Journal of Diabetology · doi:10.4103/jod.jod_22_20 · Cited by 3 · see citing works
Maasen, K., Mayén, A., Hana, C., Knaze, V., van Greevenbroek, M. M. J., Eussen, S. J. P. M., Debras, C., Stehouwer, C. D. A., Tjønneland, A., Kyrø, C., et al. (2026) · European Journal of Nutrition · doi:10.1007/s00394-026-03904-0 · Cited by 2 · see citing works
Self-citationXie, F., Zhao, J., Liu, D., Wan, Z., Sun, K., & Wang, Y. (2023) · European Journal of Nutrition · doi:10.1007/s00394-023-03253-2 · Cited by 2 · see citing works
Alipour, S., Omranipour, R., Abdollahi, A., Jahanbin, B., Gholami, B., Shab‐Bidar, S., Razavi, À. E., Selk-Ghaffari, M., Ghalkhani, F., Saberi, A., et al. (2026) · Journal of Nutrition and Metabolism · doi:10.1155/jnme/6687630 · Cited by 1 · see citing works
Dietary Patterns, Diabetes, and Aging
de Aquino, R. D. C., Previdelli, Á. N., Pedron, É. L. D. O., & Machado‐Lima, A. (2020) · Current Geriatrics Reports · doi:10.1007/s13670-020-00335-5 · Cited by 2 · see citing works
Maasen, K. (2022) · doi:10.26481/dis.20220413km
The Impact Of Dietary Advanced Glycation Endproducts
Linkens, A. M. A. (2022) · doi:10.26481/dis.20221005al
Dietary advanced glycation end products (AGE) and women's infertility
Çelik, E., & Akdevelıoğlu, Y. (2023) · Current Perspectives on Health Sciences · doi:10.58208/cphs.1355248
Glycation Compounds in Human MilkPreprint
Arena, S., Pascale, S. D., Ciaravolo, V., Monroy, M. M., Gouw, J. W., Stahl, B., Bäuerl, C., Collado, M. C., Filippo, C. D., Scaloni, A., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4865602
Liu, R., Ma, T.-T., He, Z.-L., Chen, G.-C., Gu, H.-W., & Wan, Z.-X. (2024) · Journal of food biochemistry · doi:10.1155/2024/5226432
He, H., Zhang, Y., Chen, G., Xie, F., Zeng, N., Han, R., Wang, Y., Wang, Y., & Wan, Z. (2025) · European Journal of Nutrition · doi:10.1007/s00394-025-03632-x
Bayram, H. M., & Öztürkcan, A. (2025) · Journal of Hunger & Environmental Nutrition · doi:10.1080/19320248.2025.2545539
Zhang, W., Wang, Y., He, H., Xie, F., Zeng, N., Han, R., Wang, Y., Sun, K., & Wan, Z. (2025) · British Journal Of Nutrition · doi:10.1017/s0007114525105096
Pichardo, M. S., Hunt, R. P., Peterson, L. L., Pan, K., Coday, M., Jung, S. Y., Snetselaar, L., Neuhouser, M. L., Steck, S. E., Tabung, F. K., et al. (2026) · British Journal of Cancer · doi:10.1038/s41416-026-03514-x
Zhang, C., Li, Q., Zhang, S., Zhang, Q., & Fu, L. (2026) · Food & Function · doi:10.1039/d6fo02898e
- Authors
- Cordova, R., Knaze, V., Viallon, V., Rust, P., Schalkwijk, C. G., Weiderpass, E., Wagner, K.-H., Mayen-Chacon, A.-L., Aglago, E. K., Dahm, C. C., Overvad, K., Tjønneland, A., Halkjær, J., Mancini, F. R., Boutron-Ruault, M.-C., Fagherazzi, G., Katzke, V., Kühn, T., Schulze, M. B., Boeing, H., Trichopoulou, A., Karakatsani, A., Thriskos, P., Masala, G., Krogh, V., Panico, S., Tumino, R., Ricceri, F., Spijkerman, A., Boer, J., Skeie, G., Rylander, C., Borch, K. B., Quirós, J. R., Agudo, A., Redondo-Sánchez, D., Amiano, P., Gómez-Gómez, J.-H., Barricarte, A., Ramne, S., Sonestedt, E., Johansson, I., Esberg, A., Tong, T., Aune, D., Tsilidis, K. K., Gunter, M. J., Jenab, M., & Freisling, H.
- Affiliations
- Centre international de recherche sur le cancer (FR)
- University of Vienna (AT)
- Maastricht University Medical Centre (NL)
- Aarhus University (DK)
- University of Copenhagen (DK)
- Danish Cancer Society (DK)
- Inserm (FR)
- German Cancer Research Center (DE)
- University of Potsdam (DE)
- German Institute of Human Nutrition (DE)
- Hellenic Health Foundation (GR)
- National and Kapodistrian University of Athens (GR)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Federico II University Hospital (IT)
- University of Turin (IT)
- National Institute for Public Health and the Environment (NL)
- UiT The Arctic University of Norway (NO)
- Gobierno del Principado de Asturias (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Biogipuzkoa Health Research Institute (ES)
- Universidad de Murcia (ES)
- Instituto de Salud Pública de Navarra (ES)
- Lund University (SE)
- Umeå University (SE)
- University of Oxford (GB)
- Imperial College London (GB)
- University of Ioannina (GR)
- Corresponding author
- Freisling, Heinz
- ORCID
- Knaze, V.
- Viallon, V.
- Rust, P.
- Schalkwijk, C. G.
- Weiderpass, E.
- Wagner, K-H.
- Aglago, E. K.
- Dahm, C. C.
- Overvad, K.
- Tjønneland, A.
- Halkjær, J.
- Mancini, F. R.
- Fagherazzi, G.
- Katzke, V.
- Schulze, M. B.
- Boeing, H.
- Trichopoulou, A.
- Karakatsani, A.
- Thriskos, P.
- Masala, G.
- Krogh, V.
- Panico, S.
- Tumino, R.
- Ricceri, F.
- Boer, J.
- Skeie, G.
- Rylander, C.
- Borch, K. B.
- Agudo, A.
- Amiano, P.
- Barricarte, A.
- Ramne, S.
- Sonestedt, E.
- Johansson, I.
- Esberg, A.
- Tong, T.
- Aune, D.
- Tsilidis, K. K.
- Gunter, M. J.
- Jenab, M.
- Freisling, Heinz
- Venue
- European Journal of Nutrition
- Published
- 2019-11-07
- Volume
- 59
- Issue
- 7
- Pages
- 2893-2904
- ISSN
- 1436-6207 (ISSN-L)
- 1436-6215
- OpenAlex
- W2989531702
- Cited by
- 62
- References
- 46
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 9 · 2023: 11 · 2022: 8 · 2021: 16 · 2020: 6
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- Locations
- European Journal of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- RISalud Institutional Health Repository of Andalucía (submittedVersion, other-oa)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- VBN Forskningsportal (Aalborg Universitet) (submittedVersion, other-oa)
- Rivm (National Institute for Public Health and the Environment) (submittedVersion)
- Spiral (Imperial College London) (submittedVersion)
- Research Publications (Maastricht University) (submittedVersion)
- Funders
- World Cancer Research Fund International (2015/1391)
- Fondation de France (00081166, 00089811)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Advanced Glycation End Products research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Life Sciences › Agricultural and Biological Sciences › Food Science › Potato Plant Research
- Keywords
- advanced glycation end products, weight change, weight gain, carboxymethyllysine, MG-H1, food composition, obesity, insulin resistance
- MeSH terms
- Adult, Body Weight, Chromatography, Liquid, Diet, Europe, Humans, Prospective Studies, Glycation End Products, Advanced, Tandem Mass Spectrometry
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review