Neuropsychological Deficits but Not Coping Strategies Are Related to Physical Disability in Multiple Sclerosis
Abstract
Detailed neuropsychological assessment was performed in 86 women (48 patients with stable relapsing-remitting multiple sclerosis (MS) and 38 matched healthy controls (HC)). Patients were categorized into patients without (EDSS < or =1, n = 26) and with physical disability (EDSS > or =2, n = 22). Patients with EDSS > or =2 scored significantly (P < 0.05) higher in Beck's depression inventory (BDI) and depression scores (DS) compared to HC and patients with EDSS < or =1. No significant differences were found with respect to the use of specific coping strategies between the patient groups, who preferred active (EDSS < or =1) or distracting (EDSS > or =2) strategies. Cognitive deficits were significantly increased in MS with EDSS > or =2 with regard to visuo-construction and visual memory, in particular with respect to geometric figures, compared to MS with EDSS < or =1. Significant positive correlations of depression variables (BDI, DS and BL) and depressive as well as denying coping strategies were found. Our results showed increased depression scores and increased cognitive deficits in advanced physically disabled patients, without selection of specific coping strategies. This supports an individual MS-specific neuropsychological therapeutic approach in order to improve disease related deficits together with social functioning.
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Other studies did not find differences in coping strategies of people with multiple sclerosis in accordance with their level of physical disability.
“Nevertheless, other studies did not find differences in coping strategies of pwMS in accordance with their level of physical disability [19,29,30,31].”
From Coping strategies and their impact on quality of life and physical disability of people with multiple sclerosis (2021) · cites this paper as [30]
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- Authors
- Haase, C. G., Lienemann, M., & Faustmann, P. M.
- Affiliations
- Universitätsklinikum Knappschaftskrankenhaus Bochum (DE)
- Ruhr University Bochum (DE)
- Corresponding author
- Haase, Claus G.
- ORCID
- Faustmann, Pedro M.
- Venue
- European Archives of Psychiatry and Clinical Neuroscience
- Published
- 2007-11-07
- Volume
- 258
- Issue
- 1
- Pages
- 35-39
- ISSN
- 0003-9373 (ISSN-L)
- 0940-1334
- 1433-8491
- OpenAlex
- W2061492614
- Cited by
- 18
- References
- 44
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 1 · 2021: 1 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 1 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 1.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Archives of Psychiatry and Clinical Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- multiple sclerosis, physical disability, neuropsychological deficits, cognitive impairment, depression, coping strategies, visual memory, women, relapsing-remitting multiple sclerosis, disability progression
- MeSH terms
- Adaptation, Psychological, Adult, Affect, Cognition Disorders, Disability Evaluation, Emotions, Female, Humans, Male, Middle Aged, Multiple Sclerosis, Neuropsychological Tests, Wechsler Scales, Cost of Illness
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