The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Novel swine-origin influenza A virus in humans: another pandemic knocking at the door.
Abstract
Influenza A viruses represent a continuous pandemic threat. In April 2009, a novel influenza A virus, the so-called swine-origin influenza A (H1N1) virus (S-OIV), was identified in Mexico. Although S-OIV originates from triple-reassortant swine influenza A (H1) that has been circulating in North American pig herds since the end of the 1990s, S-OIV is readily transmitted between humans but is not epidemic in pigs. After its discovery, S-OIV rapidly spread throughout the world within few weeks. In this review, we sum up the current situation and put it into the context of the current state of knowledge of influenza and influenza pandemics. Some indications suggest that a pandemic may be mild but even "mild" pandemics can result in millions of deaths. However, no reasonable forecasts how this pandemic may develop can be made at this time. Despite stockpiling by many countries and WHO, antiviral drugs will be limited in case of pandemic and resistances may emerge. Effective vaccines are regarded to be crucial for the control of influenza pandemics. However, production capacities are restricted and development/production of a S-OIV vaccine will interfere with manufacturing of seasonal influenza vaccines. The authors are convinced that S-OIV should be taken seriously as pandemic threat and underestimation of the menace by S-OIV to be by far more dangerous than its overestimation.
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“Within 4 weeks this outbreak of influenza A(H1N1) had spread to 41 countries resulting in 11,034 confirmed cases and 85 deaths (Michaelis et al., 2009; Wang and Palese, 2009).”
From Secondary bacterial infections associated with influenza pandemics (2017) · cites this paper as Michaelis et al., 2009
In the citing paper
“Although global death toll estimates vary [between 1.5 million (Gatherer, 2009) and 2–4 million (Michaelis et al., 2009)]”
From Secondary bacterial infections associated with influenza pandemics (2017) · cites this paper as Michaelis et al., 2009
In the citing paper
“Worldwide 1–2 million people died during this pandemic which was caused by the influenza strain A(H3N2) (Michaelis et al., 2009).”
From Secondary bacterial infections associated with influenza pandemics (2017) · cites this paper as Michaelis et al., 2009
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Metadata
- Authors
- Michaelis, M., Doerr, H. W., & Cinatl, J.
- Affiliations
- Goethe University Frankfurt (DE)
- Corresponding author
- Cinatl, Jindrich
- Venue
- Medical Microbiology and Immunology
- Published
- 2009-06-20
- Volume
- 198
- Issue
- 3
- Pages
- 175-183
- ISSN
- 0044-3077 (ISSN-L)
- 0300-8584
- 1432-1831
- OpenAlex
- W1999919523
- Cited by
- 127
- References
- 53
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 21 · 2022: 8 · 2021: 4 · 2020: 8 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 1 · 2015: 4 · 2014: 6 · 2013: 5 · 2012: 12
- FWCI
- 2.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Medical Microbiology and Immunology (publishedVersion)
- PubMed (publishedVersion)
- Kent Academic Repository (University of Kent) (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
- Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Keywords
- 2009 H1N1 pandemic, pandemic influenza, human-to-human transmission, pandemic preparedness, antiviral resistance, influenza vaccination, pandemic risk assessment
- MeSH terms
- Animals, Disease Outbreaks, Humans, Influenza, Human, Influenza Vaccines, Swine, Swine Diseases, Virulence, Reassortant Viruses, Influenza A Virus, H1N1 Subtype
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