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Cited by 94Vitamin D Research StudiesParathyroid Disorders and TreatmentsVitamin K Research Studies

Prevalence of vitamin D deficiency rickets in the eastern part of Turkey

Ozkan, Behzat, Doneray, Hakan, Karacan, Mehmet, Vançelik, Serhat, Yıldırım, Zuhal Keskin, Ozkan, Asuman, Kosan, Celalettin, Aydın, Kamil·2009·European Journal of Pediatrics
DOI 10.1007/s00431-008-0821-z
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Abstract

Turkey, especially its eastern part, has been accepted as endemic for vitamin D deficiency rickets (VDDR). In a study performed by our team in the region in 1998, the incidence of VDDR was 6.09% in children aged between 0-3 years. In 2005, the Ministry of Health initiated a free vitamin D supplementation campaign nationwide for every infant to eradicate VDDR. In this study, we aimed to investigate the prevalence of VDDR in children aged between 0-3 years in order to evaluate the effectiveness of this campaign. Between March 2007 and February 2008, 39,133 children aged between 0-3 years who were brought to different pediatric outpatient clinics in Erzurum, Turkey, were examined for VDDR. VDDR diagnosis was made by radiological and biochemical findings in the cases who were initially suspected of having clinical VDDR. During a one-year period, 39 (0.099%) of the 39,133 patients were diagnosed with VDDR. None of the cases with rickets was taking vitamin D supplementation. The most frequent physical findings were rachitic rosary, enlargement of the wrists, and craniotabes. The laboratory findings of the cases were compatible with VDDR; serum calcium (Ca) 7.5 +/- 1.9 mg/dL, PO4 4.4 +/- 1.3 mg/dL, alkaline phosphatase (ALP) 1,341 +/- 823, 25-hydroxyvitamin D (25 (OH) D) 5.8 +/- 2.9 ng/mL, intact parathyroid hormone (iPTH) 240 +/- 106 pg/mL. It was concluded that, although VDDR has been a continuing childhood health problem, a nationwide free vitamin D supplementation campaign initiated by the government appeared to be effective in eliminating VDDR.

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  • The Ugur et al. (2014) study was conducted in Turkey, where a national free vitamin D supplementation campaign has been implemented by government to eliminate vitamin D deficiency rickets.

    “The study by Ugur et al. (2014) [79] was conducted in Turkey, where a national free vitamin D supplementation campaign has been implemented by government to eliminate vitamin D deficiency rickets [122].”

    From Vitamin D and Autism Spectrum Disorder: A Literature Review (2016) · cites this paper as [122]

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Authors
Ozkan, B., Doneray, H., Karacan, M., Vançelik, S., Yıldırım, Z. K., Ozkan, A., Kosan, C., & Aydın, K.
Affiliations
Atatürk University (TR)
ORCID
Venue
European Journal of Pediatrics
Publisher
Springer Science and Business Media LLC
Published
2008-09-02
Volume
168
Issue
1
Pages
95-100
ISSN
  • 0340-6199 (ISSN-L)
  • 1432-1076
DOI
10.1007/s00431-008-0821-z
OpenAlex
W1993355694
Cited by
94
References
22
Citations by year
2025: 2 · 2024: 14 · 2023: 8 · 2022: 4 · 2021: 6 · 2020: 4 · 2019: 5 · 2018: 5 · 2017: 3 · 2016: 7 · 2015: 4 · 2014: 5 · 2013: 3 · 2012: 4
FWCI
4.27
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • European Journal of Pediatrics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Vitamin D Research Studies
  • Health Sciences › Medicine › Nephrology › Parathyroid Disorders and Treatments
  • Health Sciences › Nursing › Nutrition and Dietetics › Vitamin K Research Studies
Keywords
vitamin D deficiency rickets, Erzurum, craniotabes, serum 25-hydroxyvitamin D, parathyroid hormone, alkaline phosphatase, childhood rickets
MeSH terms
Child, Preschool, Demography, Humans, Infant, Infant, Newborn, Rickets, Turkey, Vitamin D, Vitamin D Deficiency, Prevalence

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