The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees
Open accessAbstract
Adhesive intercellular junctions between endothelial cells are formed by tight junctions and adherens junctions. In addition to promoting cell-to-cell adhesion, these structures regulate paracellular permeability, contact inhibition of endothelial cell growth, cell survival, and maintenance of cell polarity. Furthermore, adherens junctions are required for the correct organization of new vessels during embryo development or during tissue proliferation in the adult. Extensive research on cultured epithelial and endothelial cells has resulted in the identification of many molecular components of tight junctions and adherens junctions. Such studies have revealed the complexity of these structures, which are formed by membrane-associated adhesion proteins and a network of several intracellular signaling partners. This review focuses on the structural organization of junctional structures and their functional interactions in the endothelium of blood vessels and lymphatics. We emphasize the way that these structures regulate endothelial cell homeostasis by transferring specific intracellular signals and by modulating activation and signaling of growth factor receptors.
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Cites
Occludin: a novel integral membrane protein localizing at tight junctions.
Furuse, M., Hirase, T., Itoh, M., Nagafuchi, A., Yonemura, S., Tsukita, S., & Tsukita, S. (1993) · The Journal of cell biology · doi:10.1083/jcb.123.6.1777 · Cited by 2,580
Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice
Nitta, T., Hata, M., Gotoh, S., Seo, Y., Sasaki, H., Hashimoto, N., Furuse, M., & Tsukita, S. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302070 · Cited by 1,917
Crosstalk of tight junction components with signaling pathways
González-Mariscal, L., Tapia, R., & Chamorro, D. (2008) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2007.08.018 · Cited by 759
Itoh, M., Nagafuchi, A., Moroi, S., & Tsukita, S. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.1.181 · Cited by 677
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Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity
Giannotta, M., Trani, M., & Dejana, E. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.08.020 · Cited by 854
Self-citationWessel, F., Winderlich, M., Holm, M., Frye, M., Rivera-Galdos, R., Vockel, M., Linnepe, R., Ipe, U., Stadtmann, A., Zarbock, A., et al. (2014) · Nature Immunology · doi:10.1038/ni.2824 · Cited by 354
Passing the Vascular Barrier: Endothelial Signaling Processes Controlling Extravasation
Wettschureck, N., Strilic, B., & Offermanns, S. (2019) · Physiological Reviews · doi:10.1152/physrev.00037.2018 · Cited by 286
The Role of VE-Cadherin in Vascular Morphogenesis and Permeability Control
Dejana, E., & Vestweber, D. (2013) · Progress in Molecular Biology and Translational Science · doi:10.1016/b978-0-12-394311-8.00006-6 · Cited by 203
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Metadata
- Authors
- Dejana, E., Orsenigo, F., Molendini, C., Baluk, P., & McDonald, D. M.
- Venue
- Cell and Tissue Research
- Published
- 2008-10-15
- Volume
- 335
- Issue
- 1
- Pages
- 17-25
- ISSN
- 0302-766X (ISSN-L)
- 1432-0878
- OpenAlex
- W2136765648
- Cited by
- 210
- References
- 4
- FWCI
- 5.06
- Type
- journal article
- Language
- en
- Open access
- green
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- Dejana, E., Orsenigo, F., Molendini, C., Baluk, P., & McDonald, D. M. (2009). Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees. Cell and Tissue Research. https://doi.org/10.1007/s00441-008-0694-5
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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