Fluconazole therapy for Candida albicans urinary tract infections in infants
Abstract
Candiduria is rare in newborns and infants, occurring most often in patients with risk factors. When associated with a candidal bezoar in the urinary tract, candiduria is usually treated by systemic amphotericin B and flucytosine plus local irrigation with amphotericin B. We describe the successful treatment of five newborns with a urinary tract infection, on major urological malformations, due to Candida albicans (including three with a candidal bezoar) by fluconazole alone. No adverse effects or recurrences were observed. Fluconazole therapy permits early discharge from the hospital and seems suitable for infants and newborns with a C. albicans urinary tract infection.
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Candidal urinary tract infections accompanied by radiographic evidence of a bezoar have responded to fluconazole alone.
“candidal urinary tract infections that were accompanied by radiographic evidence of a bezoar have responded to fluconazole alone [131].”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [131]
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Guidelines for Treatment of Candidiasis
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- Authors
- Triolo, V., Gari-Toussaint, M., Casagrande, F., Garraffo, R., Dageville, C., Boutté, P., & Bérard, E.
- Affiliations
- Hôpital l'Archet (FR)
- Hôpital Pasteur (FR)
- Corresponding author
- Bérard, Etienne
- ORCID
- Bérard, Etienne
- Venue
- Pediatric Nephrology
- Published
- 2002-06-21
- Volume
- 17
- Issue
- 7
- Pages
- 550-553
- ISSN
- 0931-041X (ISSN-L)
- 1432-198X
- OpenAlex
- W2059976118
- Cited by
- 19
- References
- 17
- Citations by year
- 2024: 1 · 2020: 1 · 2015: 1 · 2014: 1 · 2013: 3 · 2012: 2
- FWCI
- 0.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Pediatric Nephrology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Epidemiology › Urinary Tract Infections Management
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Urology and Nephrology Studies
- Keywords
- fluconazole, Candida albicans, candiduria, urinary tract infection, infants, neonates, urological malformations, antifungal therapy, amphotericin B
- MeSH terms
- Antifungal Agents, Bezoars, Candidiasis, Follow-Up Studies, Humans, Infant, Infant, Newborn, Urinary Tract Infections, Fluconazole, Treatment Outcome
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