Remimazolam besilate, a benzodiazepine, has been approved for general anesthesia!!

Consensus Guidelines for the Management of Postoperative Nausea and Vomiting

Gan, T. J., Diemunsch, P. A., Habib, A. S., Kovac, A. L., Kranke, P., Meyer, T. A., Watcha, M. F., Chung, F. F., Angus, S., Apfel, C. C., et al. (2013) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000000002 · Cited by 1,483 · see citing works

Context-sensitive Half-time in Multicompartment

Hughes, M. A., Glass, P. S. A., & Jacobs, J. R. (1992) · Anesthesiology · doi:10.1097/00000542-199203000-00003 · Cited by 802 · see citing works

Society for Ambulatory Anesthesia Guidelines for the Management of Postoperative Nausea and Vomiting

Gan, T. J., Meyer, T. A., Apfel, C. C., Chung, F. F., Davis, P. J., Habib, A. S., Hooper, V. D., Kovac, A. L., Kranke, P., Myles, P. S., et al. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000295230.55439.f4 · Cited by 716 · see citing works

HAEMODYNAMIC CHANGES DURING ANAESTHESIA INDUCED AND MAINTAINED WITH PROPOFOL

Claeys, M., Gepts, E., & Camu, F. (1988) · British Journal of Anaesthesia · doi:10.1093/bja/60.1.3 · Cited by 499 · see citing works

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Kilpatrick (2007) · doi:10.1097/01.anes.0000267503.85085.c0 · Cited by 381 · see citing works

Prolonged sedation due to accumulation of conjugated metabolites of midazolam

Bauer, T., Ritz, R., Haberthür, C., Haefeli, W. E., Scollo‐Lavizzari, G., Ha, H. R., Hunkeler, W., & Sleight, A. J. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91209-6 · Cited by 334 · see citing works

Propofol infusion syndrome: a structured literature review and analysis of published case reports

Hemphill, S., McMenamin, L., Bellamy, M. C., & Hopkins, P. M. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.12.025 · Cited by 331 · see citing works

A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056): Part I. Safety, Efficacy, and Basic Pharmacokinetics

Antonik, L. J., Goldwater, D. R., Kilpatrick, G., Tilbrook, G., & Borkett, K. (2012) · Anesthesia and Analgesia · doi:10.1213/ane.0b013e31823f0c28 · Cited by 321 · see citing works

A phase III study evaluating the efficacy and safety of remimazolam (CNS 7056) compared with placebo and midazolam in patients undergoing colonoscopy.

Rex, D., Bhandari, R., Desta, T., Demicco, M., Schaeffer, C., Etzkorn, K., Barish, C., Pruitt, R., Cash, B., Quirk, D., et al. (2018) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2018.04.2351 · Cited by 260 · see citing works

A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056): Part II. Population Pharmacokinetic and Pharmacodynamic Modeling and Simulation

Wiltshire, H. R., Kilpatrick, G. J., Tilbrook, G. S., & Borkett, K. M. (2012) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e318241f68a · Cited by 215 · see citing works

A Phase IIa, Randomized, Double-Blind Study of Remimazolam (CNS 7056) Versus Midazolam for Sedation in Upper Gastrointestinal Endoscopy

Borkett, K., Riff, D., Schwartz, H., Winkle, P., Pambianco, D. J., Lees, J., & Wilhelm-Ogunbiyi, K. (2015) · Anesthesia and Analgesia · doi:10.1213/ane.0000000000000548 · Cited by 194 · see citing works

Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study

Jor, O., Máca, J., Jiřina Koutná, C., Gemrotova, M., Vymazal, T., Litschmannová, M., Ševčík, P., Reimer, P., Mikulova, V., Trlicova, M., et al. (2018) · Journal of Anesthesia · doi:10.1007/s00540-018-2532-6 · Cited by 191 · see citing works

A Phase Ib, Dose-Finding Study of Multiple Doses of Remimazolam (CNS 7056) in Volunteers Undergoing Colonoscopy

Worthington, M., Antonik, L. J., Goldwater, D. R., Lees, J., Wilhelm-Ogunbiyi, K., Borkett, K. M., & Mitchell, M. (2013) · Anesthesia and Analgesia · doi:10.1213/ane.0b013e3182a705ae · Cited by 160 · see citing works

Performance of Propofol Target-Controlled Infusion Models in the Obese

Cortínez, L. I., de la Fuente, N., Eleveld, D. J., Oliveros, A., Crovari, F. J., Sepúlveda, P., Ibacache, M. E., & Solari, S. (2014) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000000317 · Cited by 91 · see citing works

Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

Masui, K., Kira, M., Kazama, T., Hagihira, S., Mortier, E. P., & Struys, M. M. R. F. (2009) · Anesthesiology · doi:10.1097/aln.0b013e3181b799c1 · Cited by 81 · see citing works

Comparison of the sedative properties of CNS 7056, midazolam, and propofol in sheep

Upton, R. N., Martinez, A., & Grant, C. M. (2009) · British Journal of Anaesthesia · doi:10.1093/bja/aep269 · Cited by 70 · see citing works

A dose escalation study in sheep of the effects of the benzodiazepine CNS 7056 on sedation, the EEG and the respiratory and cardiovascular systems

Upton, R. N., Martinez, A. M., & Grant, C. M. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.228 · Cited by 57 · see citing works

Pharmacokinetics and pharmacodynamics of the short-acting sedative CNS 7056 in sheep

Upton, R. N., Somogyi, A. A., Martinez, A. M., Colvill, J., & Grant, C. M. (2010) · British Journal of Anaesthesia · doi:10.1093/bja/aeq260 · Cited by 49 · see citing works

Remimazolam: New Beginnings or Just a Me-Too?

Sneyd, J. R. (2012) · Anesthesia and Analgesia · doi:10.1213/ane.0b013e31823acb95 · Cited by 44 · see citing works

Paediatric total intravenous anaesthesia

Gaynor, J., & Ansermino, J. M. (2016) · BJA Education · doi:10.1093/bjaed/mkw019 · Cited by 42 · see citing works

Reduction of pain on injection of propofol using meperidine and remifentanil

Başaranoğlu, M., Erden, V., Delatioğlu, H., & Saitoğlu, L. (2005) · European Journal of Anaesthesiology · doi:10.1017/s0265021505231502 · Cited by 36 · see citing works

Waste anesthetic gas exposure and strategies for solution

Deng, H., Li, F., Cai, Y., & Xu, S. (2018) · Journal of Anesthesia · doi:10.1007/s00540-018-2448-1 · Cited by 35 · see citing works

Identification and Structure–Activity Studies of Novel Ultrashort-Acting Benzodiazepine Receptor Agonists

Stafford, J. A., Pacofsky, G. J., Cox, R. F., Cowan, J. R., Dorsey, G. F., Gonzales, S. S., Jung, D. K., Koszalka, G. W., McIntyre, M. S., Tidwell, J. H., et al. (2002) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(02)00512-7 · Cited by 30 · see citing works

Population pharmacokinetic analysis of propofol in underweight patients under general anaesthesia

Park, J. H., Choi, S., Park, J. H., Lee, K. H., Yun, H. J., Lee, E. K., Choi, B., & Noh, G. (2018) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.04.045 · Cited by 26 · see citing works

Comparison between hemodynamic effects of propofol and thiopental during general anesthesia induction with remifentanil infusion: a double-blind, age-stratified, randomized study

Hino, H., Matsuura, T., Kihara, Y., Tsujikawa, S., Mori, T., & Nishikawa, K. (2019) · Journal of Anesthesia · doi:10.1007/s00540-019-02657-x · Cited by 26 · see citing works

Effect of dexmedetomidine for attenuation of propofol injection pain in electroconvulsive therapy: a randomized controlled study

Li, X., Chen, C., Tan, F., Pan, J., Xing, J., Zhu, Q., Hei, Z., & Zhou, S. (2017) · Journal of Anesthesia · doi:10.1007/s00540-017-2430-3 · Cited by 24 · see citing works

Reversal of Midazolam-Induced Laryngospasm With Flumazenil

Davis, D. P., Hamilton, R. S., & Webster, T. H. (1998) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(98)70148-9 · Cited by 24 · see citing works

Population pharmacodynamic modelling of midazolam induced sedation in terminally ill adult patients

Franken, L. G. W., de Winter, B. C. M., Masman, A. D., van Dijk, M., Baar, F. P. M., Tibboel, D., Koch, B. C. P., van Gelder, T., & Mathôt, R. A. A. (2017) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.13442 · Cited by 22 · see citing works

Procedural sedation and analgesia in the emergency department in Japan: interim analysis of multicenter prospective observational study

On behalf of the Japanese Procedural Sedation and Analgesia Registry investigators, Norii, T., Homma, Y., Shimizu, H., Takase, H., Kim, S., Nagata, S., Shimosato, A., & Crandall, C. S. (2019) · Journal of Anesthesia · doi:10.1007/s00540-018-02606-0 · Cited by 20 · see citing works

Comparison of TIVA with different combinations of ketamine–propofol mixtures in pediatric patients

Biricik, E., Karacaer, F., Güleç, E., Sürmelioğlu, Ö., Ilgınel, M. T., & Özcengiz, D. (2017) · Journal of Anesthesia · doi:10.1007/s00540-017-2438-8 · Cited by 13 · see citing works

Context sensitive decrement times of remimazolam.

Schnider, T., & Minto, C. (2013) · Anesthesia and Analgesia · doi:10.1213/ane.0b013e3182942954 · Cited by 11 · see citing works

Evaluation of pharmacokinetic models of intravenous dexmedetomidine in sedated patients under spinal anesthesia

Obara, S., Imaizumi, T., Hakozaki, T., Hosono, A., Iseki, Y., Sanbe, N., & Murakawa, M. (2017) · Journal of Anesthesia · doi:10.1007/s00540-017-2424-1 · Cited by 10 · see citing works

Rocuronium pharmacodynamic models for published five pharmacokinetic models: age and sex are covariates in pharmacodynamic models

Masui, K., Ishigaki, S., Tomita, A., & Otake, H. (2018) · Journal of Anesthesia · doi:10.1007/s00540-018-2543-3 · Cited by 7 · see citing works

The predictive ability of six pharmacokinetic models of rocuronium developed using a single bolus: evaluation with bolus and continuous infusion regimen

Sasakawa, T., Masui, K., Kazama, T., & Iwasaki, H. (2016) · Journal of Anesthesia · doi:10.1007/s00540-016-2174-5 · Cited by 7 · see citing works

Population pharmacokinetics of palonosetron and model-based assessment of dosing strategies

Lee, S., Kim, I., Pyeon, T., Lee, S., Song, J., Rhee, J., & Jeong, S. (2019) · Journal of Anesthesia · doi:10.1007/s00540-019-02641-5 · Cited by 3 · see citing works

Remimazolam: non-clinical and clinical profile of a new sedative/anesthetic agent

Kilpatrick, G. J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.690875 · Cited by 262 · see citing works

Remimazolam: pharmacological characteristics and clinical applications in anesthesiology

Kim, K. M. (2022) · Anesthesia and Pain Medicine · doi:10.17085/apm.21115 · Cited by 250 · see citing works

Remimazolam: An Updated Review of a New Sedative and Anaesthetic

Hu, Q.-X., Liu, X., Wen, C., Li, D., & Lei, X.-F. (2022) · Drug Design, Development and Therapy · doi:10.2147/dddt.s384155 · Cited by 185 · see citing works

Safety and efficacy of remimazolam compared with propofol in induction of general anesthesia.

Dai, G., Pei, L., Duan, F., Liao, M., Zhang, Y., Zhu, M., Zhao, Z.-B., & Zhang, X. (2021) · Minerva Anestesiologica · doi:10.23736/s0375-9393.21.15517-8 · Cited by 132 · see citing works

Effect of remimazolam induction on hemodynamics in patients undergoing valve replacement surgery: A randomized, double-blind, controlled trial

Liu, T., Lai, T., Chen, J., Lu, Y., He, F., Chen, Y., & Xie, Y. (2021) · Pharmacology Research & Perspectives · doi:10.1002/prp2.851 · Cited by 146 · see citing works

Remimazolam versus propofol for sedation in gastrointestinal endoscopic procedures: a systematic review and meta-analysis.

Barbosa, E. C., Espírito Santo, P. A., Baraldo, S., & Meine, G. C. (2024) · British Journal of Anaesthesia · doi:10.1016/j.bja.2024.02.005 · Cited by 111 · see citing works

Sedation outcomes for remimazolam, a new benzodiazepine.

Oka, S., Satomi, H., Sekino, R., Taguchi, K., Kajiwara, M., Oi, Y., & Kobayashi, R. (2021) · Journal of Oral Science · doi:10.2334/josnusd.21-0051 · Cited by 84 · see citing works

Effect of Remimazolam on Postoperative Delirium in Older Adult Patients Undergoing Orthopedic Surgery: A Prospective Randomized Controlled Clinical Trial

Yang, J.-J., Lei, L., Qiu, D., Chen, S., Xing, L., Zhao, J., Mao, Y.-Y., & Yang, J.-J. (2023) · Drug Design, Development and Therapy · doi:10.2147/dddt.s392569 · Cited by 80 · see citing works

A population pharmacokinetic model of remimazolam for general anesthesia and consideration of remimazolam dose in clinical practice

Masui, K., Stöhr, T., Pesic, M., & Tonai, T. (2022) · Journal of Anesthesia · doi:10.1007/s00540-022-03079-y · Cited by 79 · see citing works

Re-sleeping after reversal of remimazolam by flumazenil

Yamamoto, T., Kurabe, M., & Kamiya, Y. (2021) · Journal of Anesthesia · doi:10.1007/s00540-021-02915-x · Cited by 74 · see citing works

Caution!! Reappearance of remimazolam effect after a flumazenil bolus: a larger bolus of flumazenil and a lower total remimazolam clearance are higher risks

Masui, K. (2022) · Journal of Anesthesia · doi:10.1007/s00540-022-03107-x · Cited by 55 · see citing works

Effect of remimazolam on the incidence of delirium after transcatheter aortic valve implantation under general anesthesia: a retrospective exploratory study

Kaneko, S., Morimoto, T., Ichinomiya, T., Murata, H., Yoshitomi, O., & Hara, T. (2022) · Journal of Anesthesia · doi:10.1007/s00540-022-03148-2 · Cited by 48 · see citing works

Efficacy and Safety Profile of Remimazolam for Sedation in Adults Undergoing Short Surgical Procedures

Morimoto, Y. (2022) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 49 · see citing works

Hypotension after general anaesthesia induction using remimazolam or propofol in geriatric patients undergoing sevoflurane anaesthesia with remifentanil: a single-centre, double-blind, randomised controlled trial.

Takaki, R., Yokose, M., Mihara, T., Saigusa, Y., Tanaka, H., Yamamoto, N., Masui, K., & Goto, T. (2024) · British Journal of Anaesthesia · doi:10.1016/j.bja.2024.04.013 · Cited by 45 · see citing works

Ringer's acetate solution-induced precipitation of remimazolam

Sasaki, H., Hoshijima, H., & Mizuta, K. (2021) · British Journal of Anaesthesia · doi:10.1016/j.bja.2020.11.021 · Cited by 38 · see citing works

Efficacy and safety of remimazolam besylate combined with alfentanil in painless gastroscopy: a randomized, single-blind, parallel controlled study

Xu, C., He, L., Ren, J., Zhou, J., Guo, H., Chen, N., Chen, H., & Lv, Y. (2022) · Contrast Media & Molecular Imaging · doi:10.1155/2022/7102293 · Cited by 36 · see citing works

Remimazolam Compared to Propofol During Hysteroscopy: A Safety and Efficacy Analysis

Fan, S., Zhu, Y., Sui, C., Li, Q., Jiang, W., & Zhang, L. (2023) · Pain and Therapy · doi:10.1007/s40122-023-00483-4 · Cited by 28 · see citing works

Remimazolam: its clinical pharmacology and evolving role in anesthesia and sedation practice

Masui, K. (2024) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0000000000001384 · Cited by 26 · see citing works

Remimazolam Tolerance in Long-term Benzodiazepine Users: A Case Report of 2 Cases.

Yoshikawa, H., Hosokawa, M., Kashima, Y., Oki, S., & Masui, K. (2021) · A&A practice · doi:10.1213/xaa.0000000000001460 · Cited by 26 · see citing works

Clinical Pharmacokinetics and Pharmacodynamics of Remimazolam

de Jong, B., Eleveld, D., Mason, K., & Struys, M. (2025) · Clinical Pharmacokinetics · doi:10.1007/s40262-025-01548-7 · Cited by 35 · see citing works

Anesthetic management of super-elderly patients with remimazolam: a report of two cases

Nakayama, J., Ogihara, T., Yajima, R., Innami, Y., & Ouchi, T. (2021) · JA Clinical Reports · doi:10.1186/s40981-021-00474-4 · Cited by 27 · see citing works

Remimazolam in a Pediatric Patient With a Suspected Family History of Malignant Hyperthermia

Petkus, H., Willer, B., & Tobias, J. (2022) · Journal of Medical Cases · doi:10.14740/jmc3977 · Cited by 31 · see citing works

Remimazolam: A Novel Option for Procedural Sedation in High Risk Patients

Pantos, M. M., Kennedy, D. R., & Nemec, E. C. (2021) · Journal of Pharmacy Practice · doi:10.1177/08971900211027303 · Cited by 28 · see citing works

Remimazolam Requires Less Vasopressor Support during Induction and Maintenance of General Anesthesia in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Retrospective Analysis from a Single Center

Miyoshi, H., Watanabe, T., Kido, K., Kamiya, S., Otsuki, S., Narasaki, S., Toyota, Y., Kondo, T., Horikawa, Y. T., Saeki, N., et al. (2022) · BioMed Research International · doi:10.1155/2022/6386606 · Cited by 27 · see citing works

Remimazolam for Pediatric Procedural Sedation: Results of an Institutional Pilot Program

Hirano, T., Kimoto, Y., Kuratani, N., Cavanaugh, D., & Mason, K. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12185937 · Cited by 32 · see citing works

Two cases of circulatory collapse due to suspected remimazolam anaphylaxis

Uchida, S., Takekawa, D., Kitayama, M., & Hirota, K. (2022) · JA Clinical Reports · doi:10.1186/s40981-022-00508-5 · Cited by 23 · see citing works

Pediatric sedation using dexmedetomidine and remimazolam for magnetic resonance imaging

Shioji, N., Everett, T., Suzuki, Y., & Aoyama, K. (2021) · Journal of Anesthesia · doi:10.1007/s00540-021-02957-1 · Cited by 22 · see citing works

Remimazolam in Cardiac Anesthesia: Analysis of Recent Data.

Ripoll, J. G., Orjuela, R. B., Kanaparthi, A., Soto, J. C. D., ElSaban, M., Peclat, T. R., Wieruszewski, P., Abcejo, A. S., Chang, M. G., Bittner, E. A., et al. (2024) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2024.08.030 · Cited by 19 · see citing works

Effectiveness of remimazolam in preventing postoperative delirium in elderly patients with proximal femoral fractures

Fujimoto, D., Obata, N., & Mizobuchi, S. (2024) · Journal of Anesthesia · doi:10.1007/s00540-024-03339-z · Cited by 18 · see citing works

Effects of Remimazolam and Propofol on Ca 2+ Regulation by Ryanodine Receptor 1 with Malignant Hyperthermia Mutation

Watanabe, T., Miyoshi, H., Noda, Y., Narasaki, S., Morio, A., Toyota, Y., Kimura, H., Mukaida, K., Yasuda, T., & Tsutsumi, Y. M. (2021) · BioMed Research International · doi:10.1155/2021/8845129 · Cited by 22 · see citing works

Equilibration rate constant, ke0, to determine effect-site concentration for the Masui remimazolam population pharmacokinetic model in general anesthesia patients

Masui, K., & Hagihira, S. (2022) · Journal of Anesthesia · doi:10.1007/s00540-022-03099-8 · Cited by 22 · see citing works

Remimazolam Compared to Propofol for Total Intravenous Anesthesia with Remifentanil on the Recovery of Psychomotor Function: A Randomized Controlled Trial

Shimizu, T., Takasusuki, T., & Yamaguchi, S. (2023) · Advances in Therapy · doi:10.1007/s12325-023-02615-w · Cited by 19 · see citing works

Efficacy of remimazolam tosilate versus propofol for total intravenous anaesthesia in urological surgery

Lan, H., Cao, H., Liu, S., Gong, X., Huang, X., Rong, H., Xu, B., Chen, H.-H., Jiao, Z. Y., Lin, Y., et al. (2024) · European Journal of Anaesthesiology · doi:10.1097/eja.0000000000001938 · Cited by 20 · see citing works

Prevention of postoperative nausea and vomiting after gynaecological day surgery under remimazolam general anesthesia: a randomized double-blind controlled study

Yi, F.-X., Xiao, H.-H., Zhu, T., Man, Y., & Ji, F.-C. (2022) · BMC Anesthesiology · doi:10.1186/s12871-022-01835-x · Cited by 19 · see citing works

Anesthetic management for a patient with myotonic dystrophy with remimazolam

Morimoto, Y., Yoshimatsu, A., & Yoshimura, M. (2021) · JA Clinical Reports · doi:10.1186/s40981-021-00413-3 · Cited by 20 · see citing works

Hypotension after general anesthesia induction using remimazolam in geriatric patients: Protocol for a double-blind randomized controlled trial

Yokose, M., Takaki, R., Mihara, T., Saigusa, Y., Yamamoto, N., Masui, K., & Goto, T. (2022) · PLoS ONE · doi:10.1371/journal.pone.0275451 · Cited by 18 · see citing works

Remimazolam anesthesia for transcatheter mitral valve repair in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome: a case report

Kitaura, A., Kosumi, R., Iwamoto, T., & Nakao, S. (2022) · JA Clinical Reports · doi:10.1186/s40981-022-00528-1 · Cited by 18 · see citing works

Review of remimazolam and sedatives in the intensive care unit

Choi, H., & Song, I. (2022) · Acute and Critical Care · doi:10.4266/acc.2022.00619 · Cited by 20 · see citing works

Remimazolam’s Effects on Postoperative Nausea and Vomiting Are Similar to Those of Propofol after Laparoscopic Gynecological Surgery: A Randomized Controlled Trial

Matsumoto, A., Satomi, S., Kakuta, N., Narasaki, S., Toyota, Y., Miyoshi, H., Horikawa, Y. T., Saeki, N., Tanaka, K., & Tsutsumi, Y. M. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12165402 · Cited by 18 · see citing works

Remimazolam: an ultrashort-acting intravenous anesthetic suitable for general anesthesia

CARDIA, L. (2021) · Minerva Anestesiologica · doi:10.23736/s0375-9393.21.16006-7 · Cited by 16 · see citing works

How to administer remimazolam for anesthesia induction

Hirata, N., Hayamizu, K., & Yamakage, M. (2020) · Journal of Anesthesia · doi:10.1007/s00540-020-02864-x · Cited by 16 · see citing works

A case of intravenous line occlusion when using Acetated Ringer's solution and remimazolam

Yoshida, K., Tanaka, S., & Watanabe, K. (2021) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2021.110190 · Cited by 16 · see citing works

Safety and efficacy of remimazolam for general anesthesia in elderly patients undergoing laparoscopic cholecystectomy: a randomized controlled trial

So, K., Park, J., & Kim, S. H. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1265860 · Cited by 14 · see citing works

Comparison of Remimazolam versus Sevoflurane on the Postoperative Quality of Recovery in Cervical Spine Surgery: A Prospective Randomized Controlled Double-Blind Trial

Lee, J., Han, D.-W., Kim, N., Kim, K., Yang, Y., Yang, J., Lee, H., & Kim, M. (2024) · Drug Design, Development and Therapy · doi:10.2147/dddt.s441622 · Cited by 12 · see citing works

Incompatibility of remimazolam besylate with Ringer’s acetate infusion resulting in total occlusion of an intravenous catheter

Matsuo, M., Okada, K., Onuki, Y., & Yamazaki, M. (2021) · BMJ Case Reports · doi:10.1136/bcr-2021-241622 · Cited by 14 · see citing works

Efficacy and safety of remimazolam tosylate for sedation during upper gastrointestinal endoscopy: study protocol for a multicenter randomized controlled trial

Zhu, H.-C., Su, Z., Huai, X., Chen, C., Zhang, X., Zhou, J., & Su, D. (2022) · Trials · doi:10.1186/s13063-022-06935-0 · Cited by 11 · see citing works

Comparison of Remimazolam versus Dexmedetomidine on Hemodynamics in Older Patients Under Lower Extremity Orthopedic Surgery with Spinal Anesthesia: A Randomized Controlled Trial

Wang, D., Liu, Z., Zhang, W., Li, S., Chen, Y., Jiang, C., Su, N., Liu, T., Li, X., & Bi, C. (2025) · Drug Design Development and Therapy · doi:10.2147/dddt.s504371 · Cited by 13 · see citing works

Efficacy and safety of remimazolam for procedural sedation during ultrasound-guided transversus abdominis plane block and rectus sheath block in patients undergoing abdominal tumor surgery: a single-center randomized controlled trial

Xiao, Y., Wei, R., Chen, L., Chen, Y., & Kong, L. (2022) · BMC Anesthesiology · doi:10.1186/s12871-022-01927-8 · Cited by 13 · see citing works

An Adequate Infusion Rate of Remimazolam for Induction of General Anesthesia in Adult Patients: A Prospective Up-and-Down Dose-Finding Study

Jeong, H., Kim, H.-R., & Ahn, H. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12051763 · Cited by 13 · see citing works

Remimazolam-Based Anesthesia in Patients with Heart Failure Due to Mitral Regurgitation and Low Left Ventricular Function: A Case Series

Kitaura, A., Sakamoto, H., Hamasaki, S., Tsukimoto, S., & Nakajima, Y. (2023) · Medicina · doi:10.3390/medicina59122136 · Cited by 10 · see citing works

Remimazolam attenuates inflammation and kidney fibrosis following folic acid injury

Song, J., Yu, W., Chen, S., Huang, J., Zhou, C., & Liang, H. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176342 · Cited by 12 · see citing works

Comparison of remimazolam and sevoflurane for general anesthesia during transcatheter aortic valve implantation: a randomized trial

Harimochi, S., Godai, K., Nakahara, M., & Matsunaga, A. (2024) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-024-02900-4 · Cited by 12 · see citing works

Change in cerebral circulation during the induction of anesthesia with remimazolam

Soejima, T., Ueda, K., Hasegawa, S., Motoe, H., Okada, K., Ito, Y. M., Hoshino, K., & Morimoto, Y. (2022) · Journal of Anesthesia · doi:10.1007/s00540-022-03135-7 · Cited by 11 · see citing works

Remimazolam anaphylaxis in a patient not allergic to brotizolam: a case report and literature review

Nakai, T., Kako, E., Ota, H., So, M., & Sobue, K. (2024) · BMC Anesthesiology · doi:10.1186/s12871-024-02591-w · Cited by 11 · see citing works

A New Anesthetic, Remimazolam, Is Useful in the Management of Anesthesia in Patients with Liver Cirrhosis

Onoda, A., & Suzuki, Y. (2022) · Case reports in anesthesiology · doi:10.1155/2022/9268454 · Cited by 10 · see citing works

Quality of Postoperative Recovery in Total Intravenous Anesthesia between Remimazolam and Propofol for Intraoperative Neurophysiological Monitoring: A Prospective Double-Blind Randomized Controlled Trial

Lee, J., Han, D.-W., Song, Y., Lee, J., Jeon, S., & Kim, M. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14040382 · Cited by 8 · see citing works

Simulation of residual sedation effect of remimazolam: pharmacokinetic–pharmacodynamic simulation can be an additional standard anesthesia monitoring method

Obara, S. (2021) · Journal of Anesthesia · doi:10.1007/s00540-021-02963-3 · Cited by 10 · see citing works

An update on remimazolam and anaphylaxis.

Cinotti, R. (2023) · European Journal of Anaesthesiology · doi:10.1097/eja.0000000000001794 · Cited by 11 · see citing works

Anesthetic Management Using Remimazolam in a Hemodialysis Patient.

Nishioka, Y., Miyake, S., Hamaoka, M., Miyake, K., Fujimoto, M., Higuchi, H., & Miyawaki, T. (2023) · Anesthesia Progress · doi:10.2344/anpr-70-02-06 · Cited by 7 · see citing works

Study on the combination of remazolam besylate and sufentanil in elderly patients with percutaneous vertebroplasty

Liu, Y., Wang, D., Chi, W., & Hu, F. (2023) · Biotechnology and Genetic Engineering Reviews · doi:10.1080/02648725.2023.2193047 · Cited by 9 · see citing works

Predicting the amount of flumazenil needed to antagonize remimazolam.

Aya, D., Hoshi, T., & Yamaguchi, H. (2021) · European Journal of Gastroenterology and Hepathology · doi:10.1097/meg.0000000000002201 · Cited by 9 · see citing works

Clinical experience with remimazolam in pediatric anesthesiology: An educational focused review

Tobias, J. D. (2024) · Paediatric anaesthesia · doi:10.1111/pan.14970 · Cited by 18 · see citing works

Remimazolam versus propofol for postoperative delirium prevention in geriatric surgery: A systematic review and meta-analysis of randomized controlled trials

Tong, R.-J., Lv, Y.-Z., Shi, Y.-F., Lai, L., & Shen, Q.-H. (2025) · Aging Clinical and Experimental Research · doi:10.1007/s40520-025-03166-6 · Cited by 8 · see citing works

Delayed emergence due to remimazolam extravasation

Uchida, S., Takekawa, D., & Hirota, K. (2022) · JA Clinical Reports · doi:10.1186/s40981-022-00584-7 · Cited by 8 · see citing works

Patient-controlled sedation using remimazolam during third molar extraction: a case report

Park, K. N., Karm, M.-H., Seo, K., Kim, H. J., & Ryoo, S.-H. (2024) · Journal of Dental Anesthesia and Pain Medicine · doi:10.17245/jdapm.2024.24.1.75 · Cited by 7 · see citing works

Effects of different doses of remimazolam on the quality of sedation and cardiac function in elderly patients: a double-blind randomised controlled study

Liu, M., Feng, Q., Chen, H., Li, J., & Shi, J. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1453608 · Cited by 4 · see citing works

Comparison of the effects of remimazolam and propofol on postoperative delirium in elderly surgical patients: a meta-analysis

Huang, J., Xiao, Z., Lao, J., Pan, L., Chen, Z., & Lin, Z. (2025) · BMC Anesthesiology · doi:10.1186/s12871-025-03197-6 · Cited by 7 · see citing works

Remimazolam anesthesia in pediatric patients undergoing cardiac catheterization for congenital heart disease: a retrospective observational study

Hosokawa, M., Takahashi, Y., Ueno, T., Oe, K., & Masui, K. (2024) · Journal of Anesthesia · doi:10.1007/s00540-024-03395-5 · Cited by 9 · see citing works

Comparison of the anesthetic effects of remimazolam tosilate and remimazolam besylate in daytime hysteroscopic surgery

Zhang, H., Fu, M., Yue, F., Wei, Y., Shi, X., Yu, S., & Ji, F. (2024) · BMC Anesthesiology · doi:10.1186/s12871-024-02773-6 · Cited by 7 · see citing works

Two Cases of Inadequate Response to Remimazolam

Kitaura, A., Hamasaki, S., Sakamoto, H., Tsukimoto, S., & Nakajima, Y. (2023) · Cureus · doi:10.7759/cureus.42576 · Cited by 8 · see citing works

Remimazolam: a comprehensive review

Aszkiełowicz, A., Kapłan, C., Kapica, P., & Marszałek, R. (2025) · Anaesthesiology Intensive Therapy · doi:10.5114/ait/210611 · Cited by 10 · see citing works

Pharmacological profiles and mechanism of action of remimazolam for ICU sedation

Masui, K. (2026) · Journal of Intensive Care · doi:10.1186/s40560-026-00858-7 · Cited by 6 · see citing works

Efficacy and safety of remimazolam tosilate in anesthesia for short otolaryngology surgery

Cheng, W., Cheng, Y., He, H., Zhou, D.-D., Wang, J., Zhang, Y., & Wang, Z. (2024) · BMC Anesthesiology · doi:10.1186/s12871-024-02790-5 · Cited by 7 · see citing works

Sedation-analgesia techniques for nonoperating room anesthesia: an update

Khorsand, S., Karamchandani, K., & Joshi, G. P. (2022) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0000000000001123 · Cited by 6 · see citing works

Postoperative nausea and vomiting after artificial joint replacement surgery: comparison between remimazolam and sevoflurane, a propensity score analysis

Yunoki, K., & Mima, H. (2023) · Journal of Anesthesia · doi:10.1007/s00540-023-03214-3 · Cited by 5 · see citing works

Recovery of sedation and psychomotor and equilibrium functions following remimazolam anesthesia with or without flumazenil: a randomized, double-blind, controlled trial

Suzuki, M., Koshika, K., & Ichinohe, T. (2025) · Journal of Dental Anesthesia and Pain Medicine · doi:10.17245/jdapm.2025.25.1.55 · Cited by 5 · see citing works

Remimazolam: A Novel Frontier in Procedural Sedation for Emergency Medicine

Bradshaw, J. C., Lester, L., Greer, M. R., & Leon, D. A. (2025) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2025.09.031 · Cited by 5 · see citing works

Postoperative Heart Failure with Preserved Ejection Fraction Induced by Flumazenil Administered for Remimazolam Antagonism

Koh, K., Omae, T., Sakuraba, S., Kumemura, M., Yamazaki, S., & Yunoki, H. (2022) · Case Reports in Anesthesiology · doi:10.1155/2022/8923008 · Cited by 5 · see citing works

Population pharmacokinetic analysis of remimazolam after continuous infusion for sedation in critically ill patients

Chen, J.-C., Wang, X., Chen, D., Liu, X.-L., Peng, K.-Y., Tang, R.-Z., Hu, L.-H., Wang, Y.-R., Bai, Y.-P., Chang, L., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1526266 · Cited by 3 · see citing works

Remifentanil enhances the sedative effect of remimazolam during anesthesia induction in patients undergoing hysteroscopy: a randomized controlled trial

Xie, Z., Liao, Y., Chen, Q., Zhang, C.-M., Luo, J., Cao, H., Lin, Y., Lan, H., Huang, X., & Guan, X. (2025) · Annals medicus · doi:10.1080/07853890.2025.2534850 · Cited by 4 · see citing works

Comparative study of the efficacy and safety of remimazolam and midazolam for general anesthesia in elderly patients: a randomized controlled trial

Yang, W.-J., Geng, Z.-L., Gao, Y.-Y., Cui, C.-Y., Chen, Z.-Z., Tian, Z.-W., Guo, X.-L., Zhang, Y.-N., Wang, L., Huo, R., et al. (2025) · Perioperative Medicine · doi:10.1186/s13741-025-00525-9 · Cited by 1 · see citing works

Remimazolam Induction in a Patient with Super-Super Obesity and Obstructive Sleep Apnea: A Case Report

Lee, S.-H., & Han, H. (2023) · Medicina · doi:10.3390/medicina59071247 · Cited by 4 · see citing works

Development and validation of an HPLC-MS/MS assay for the quantitative analysis of remimazolam in critically ill patients

Chen, J., Wu, M., Xiao, Y., Chen, D., Wang, Y., Bai, Y., Wang, X., Hu, L., Huang, R., Chen, C., et al. (2023) · International Journal of Mass Spectrometry · doi:10.1016/j.ijms.2023.117120 · Cited by 3 · see citing works

Comparison of Hemodynamic Effects of Remimazolam and Midazolam During Anesthesia Induction in Patients Undergoing Cardiovascular Surgery: A Single-Center Retrospective and Exploratory Study

Shintani, R., Ichinomiya, T., Tashiro, K., Miyazaki, Y., Tanaka, T., Kaneko, S., Iwasaki, N., Sekino, M., Maekawa, T., & Hara, T. (2024) · Cureus · doi:10.7759/cureus.72032 · Cited by 3 · see citing works

Efficacy and Safety of Remimazolam versus Dexmedetomidine and Midazolam in Awake Endotracheal Intubation for Difficult Airway Patients: A Randomized Controlled Study

Tang, L., Zhang, M., Guo, J., Zhang, M., Chen, W., Zhao, X., Huang, J., & Sheng, L. (2025) · Drug Design Development and Therapy · doi:10.2147/dddt.s564228 · Cited by 2 · see citing works

Remimazolam: A New Ingress in Cardiac Surgical Intensive Care Unit

Choudhury, M., & Kapoor, P. (2023) · Journal of Cardiac Critical Care TSS · doi:10.25259/jccc_25_2023 · Cited by 2 · see citing works

Application Progress of Rimazzolam in Anesthesiology

Li, Y.-F. (2024) · Advances in Clinical Medicine · doi:10.12677/acm.2024.1441355 · Cited by 1 · see citing works

The sedation efficacy of different doses of remimazolam in elderly patients with regional nerve block anaesthesia

Yang, W.-J., Geng, Z.-L., Chen, Z.-Z., Cui, C.-Y., Tian, Z.-W., Guo, X.-L., Zhang, Y.-N., Wang, L., Huo, R., Ma, C.-W., et al. (2024) · European Journal of Medical Research · doi:10.1186/s40001-024-02204-9 · Cited by 3 · see citing works

Effective anesthetic management with remimazolam and ketamine without muscle relaxants for parotidectomy in a patient with myotonic dystrophy: A case report

Ishida, Y., Habu, M., & Toba, Y. (2022) · Medicine · doi:10.1097/md.0000000000030415 · Cited by 2 · see citing works

Research Progress of Remazolam for General Anesthesia in Elderly Patients

Jiang, X. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.13112553 · Cited by 1 · see citing works

Remimazolam Anesthesia for Thyroid Surgery

Nakagawa, S., Shakuo, T., Matsudo, S., Soda, H., & Shida, K. (2023) · Case Reports in Anesthesiology · doi:10.1155/2023/2352693 · Cited by 1 · see citing works

Monitored Anesthesia Care Under a Combination of Low-Dose Remimazolam Infusion and Flumazenil Antagonism: A Case Report

Kamata, K., & Masui, K. (2023) · Cureus · doi:10.7759/cureus.46728 · Cited by 1 · see citing works

Research on the Effects of Remimazolam on Hemodynamics and Postoperative Cognitive Function during Anesthesia Induction in Off-Pump Coronary Artery Bypass Grafting

Wang, Z.-K. (2024) · Advances in Clinical Medicine · doi:10.12677/acm.2024.1461750 · Cited by 1 · see citing works

Remimazolam – Update zu Grundlagen und klinischem Potenzial

Scheckenbach, V., & Drexler, B. (2024) · Die Anaesthesiologie · doi:10.1007/s00101-024-01450-0 · Cited by 1 · see citing works

Remimazolam: Five Years of Clinical Experience Since Its First-in-World Approval in Japan

Yamakage, M. (2025) · Open Journal of Anesthesiology · doi:10.4236/ojanes.2025.1512022 · Cited by 1 · see citing works

Palladium Catalyzed Synthesis of Substituted 2-Aminobenzophenone Derivatives Via Oxidative Ring Opening of Oxindoles

Kesarkar, D. J., Hote, B. S., & Kashid, B. B. (2026) · Polycyclic aromatic compounds · doi:10.1080/10406638.2026.2648229 · Cited by 1 · see citing works

Mechanisms of Bone Tissue Remodeling in Young Persons with Osteoarthritis on the Background of Obesity

Litvynova, A. M., & Пасієшвілі, Л. М. (2022) · Ukraïnsʹkij žurnal medicini bìologìï ta sportu · doi:10.26693/jmbs07.03.153 · Cited by 1 · see citing works

Remimazolam besylate; overview of a novel benzodiazepine for general anesthesia

Morimoto, Y. (2022) · Anaesthesia Pain & Intensive Care · doi:10.35975/apic.v26i3.1891 · Cited by 1 · see citing works

Effectiveness of general anaesthesia with remimazolam tosilate on intraoperative haemodynamics and postoperative recovery: study protocol for a randomised, positive-controlled, pragmatic clinical trial (GARTH trial)

Lu, C., Kang, Y., Luo, Q.-H., Zhong, F., Cai, Y., Zhang, G., Guo, Z., Zhang, S., Ma, J., & Shu, H. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-073024

Remimazolam Anesthesia for Modified Electroconvulsive Therapy Mitigates Postoperative Agitation

Shimono, S., Shakuo, T., Yamamura, A., Hashimoto, M., Masuda, R., & Shida, K. (2024) · Cureus · doi:10.7759/cureus.71037 · Cited by 1 · see citing works

Remimazolam: First Approval

Keam, S. J. (2020) · Figshare · doi:10.6084/m9.figshare.12017124

Remimazolam – Update zu Grundlagen und klinischem Potenzial

Scheckenbach, V., & Drexler, B. (2024) · Die Anaesthesiologie · doi:10.1007/s00101-024-01450-0 · Cited by 1 · see citing works

Remimazolam: A New Ultra Short Acting Benzodiazepine

(2016) · Journal of Anesthesia & Critical Care Open Access · doi:10.15406/jaccoa.2016.04.00166 · Cited by 3 · see citing works

Remimazolam: an ultrashort-acting intravenous anesthetic suitable for general anesthesia

CARDIA, L. (2021) · Minerva Anestesiologica · doi:10.23736/s0375-9393.21.16006-7 · Cited by 16 · see citing works

Research Progress of Remimazolam in Induction and Maintenance of General An-esthesia

Yan, J.-W. (2022) · Advances in Clinical Medicine · doi:10.12677/acm.2022.126759