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Cited by 325

The DOI matches its Crossref record; 410 of the 410 references it cites were found in a registry or an index.

Challenges of neuropathic pain: focus on diabetic neuropathy

Open access
Rosenberger, Daniela C., Blechschmidt, Vivian, Timmerman, Hans, Wolff, André, Treede, Rolf-Detlef·2020·Journal of Neural Transmission

Abstract

Neuropathic pain is a frequent condition caused by a lesion or disease of the central or peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain is diabetic neuropathy. Its complex pathophysiology is not yet fully elucidated, which contributes to underassessment and undertreatment. A mechanism-based treatment of painful diabetic neuropathy is challenging but phenotype-based stratification might be a way to develop individualized therapeutic concepts. Our goal is to review current knowledge of the pathophysiology of peripheral neuropathic pain, particularly painful diabetic neuropathy. We discuss state-of-the-art clinical assessment, validity of diagnostic and screening tools, and recommendations for the management of diabetic neuropathic pain including approaches towards personalized pain management. We also propose a research agenda for translational research including patient stratification for clinical trials and improved preclinical models in relation to current knowledge of underlying mechanisms.

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Metadata

Authors
Rosenberger, D. C., Blechschmidt, V., Timmerman, H., Wolff, A., & Treede, R.-D.
Venue
Journal of Neural Transmission
Published
2020-02-08
Volume
127
Issue
4
Pages
589-624
ISSN
  • 0300-9564 (ISSN-L)
  • 1435-1463
OpenAlex
W3005211134
Cited by
325
References
410
FWCI
18.86
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Challenges of neuropathic pain: focus on diabetic neuropathy. https://app.cochat.ai/papers/10.1007/s00702-020-02145-7
The paper
Rosenberger, D. C., Blechschmidt, V., Timmerman, H., Wolff, A., & Treede, R.-D. (2020). Challenges of neuropathic pain: focus on diabetic neuropathy. Journal of Neural Transmission. https://doi.org/10.1007/s00702-020-02145-7

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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