Cited by 211Menstrual Health and DisordersMaternal Mental Health During Pregnancy and PostpartumMenopause: Health Impacts and Treatments

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ISPMD consensus on the management of premenstrual disorders

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Consensus Group of the International Society for Premenstrual Disorders, Nevatte, Tracy, O’Brien, Patrick Michael Shaughn, Bäckström, Torbjorn, Brown, Candace, Dennerstein, Lorraine, Endicott, Jean, Epperson, C. Neill, Eriksson, Elias, Freeman, Ellen W., Halbreich, Uriel, Ismail, Khalid, Panay, Nicholas, Pearlstein, Teri, Rapkin, Andrea, Reid, Robert, Rubinow, David, Schmidt, Peter, Steiner, Meir, Studd, John, Sundström-Poromaa, Inger, Yonkers, Kimberly·2013·Archives of Women s Mental Health

DOI 10.1007/s00737-013-0346-yPMC PMC3955202

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Abstract

The second consensus meeting of the International Society for Premenstrual Disorders (ISPMD) took place in London during March 2011. The primary goal was to evaluate the published evidence and consider the expert opinions of the ISPMD members to reach a consensus on advice for the management of premenstrual disorders. Gynaecologists, psychiatrists, psychologists and pharmacologists each formally presented the evidence within their area of expertise; this was followed by an in-depth discussion leading to consensus recommendations. This article provides a comprehensive review of the outcomes from the meeting. The group discussed and agreed that careful diagnosis based on the recommendations and classification derived from the first ISPMD consensus conference is essential and should underlie the appropriate management strategy. Options for the management of premenstrual disorders fall under two broad categories, (a) those influencing central nervous activity, particularly the modulation of the neurotransmitter serotonin and (b) those that suppress ovulation. Psychotropic medication, such as selective serotonin reuptake inhibitors, probably acts by dampening the influence of sex steroids on the brain. Oral contraceptives, gonadotropin-releasing hormone agonists, danazol and estradiol all most likely function by ovulation suppression. The role of oophorectomy was also considered in this respect. Alternative therapies are also addressed, with, e.g. cognitive behavioural therapy, calcium supplements and Vitex agnus castus warranting further exploration.

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Authors: Consensus Group of the International Society for Premenstrual Disorders, Nevatte, T., O’Brien, P. M. S., Bäckström, T., Brown, C., Dennerstein, L., Endicott, J., Epperson, C. N., Eriksson, E., Freeman, E. W., Halbreich, U., Ismail, K., Panay, N., Pearlstein, T., Rapkin, A., Reid, R., Rubinow, D., Schmidt, P., Steiner, M., Studd, J., Sundström-Poromaa, I., & Yonkers, K.
Affiliations: Keele University (GB)
Royal Stoke University Hospital (GB)
University of Tennessee Health Science Center (US)
The University of Melbourne (AU)
Columbia University (US)
University of Pennsylvania (US)
University at Buffalo, State University of New York (US)
Queen Charlotte's and Chelsea Hospital (GB)
Brown University (US)
University of California, Los Angeles (US)
University of North Carolina at Chapel Hill (US)
National Institute of Mental Health (US)
Chelsea and Westminster Hospital (GB)
Uppsala University (SE)
Corresponding author: Nevatte, Tracy
ORCID: Nevatte, Tracy
Epperson, C. Neill
Eriksson, Elias
Freeman, Ellen W.
Halbreich, Uriel
Panay, Nicholas
Rapkin, Andrea
Reid, Robert
Rubinow, David
Schmidt, Peter
Steiner, Meir
Yonkers, Kimberly
Venue: Archives of Women s Mental Health
Publisher: Springer Science and Business Media LLC
Published: 2013-04-27
Volume: 16
Issue: 4
Pages: 279-291
ISSN: 1434-1816 (ISSN-L)
1435-1102
DOI: 10.1007/s00737-013-0346-y
PMC: PMC3955202
OpenAlex: W2024556146
Cited by: 211
References: 111
Citations by year: 2026: 8 · 2025: 13 · 2024: 16 · 2023: 21 · 2022: 16 · 2021: 17 · 2020: 45 · 2019: 16 · 2018: 5 · 2017: 19 · 2016: 10 · 2015: 14 · 2014: 10 · 2013: 1
FWCI: 11.90
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Archives of Women s Mental Health (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
UNC Libraries
Funders: National Institutes of Health
National Institute of Mental Health (ZIAMH002865)
National Institute on Drug Abuse (K24DA030301, R01DA018359)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords: premenstrual disorders, premenstrual dysphoric disorder, premenstrual syndrome, management recommendations, serotonin modulation, selective serotonin reuptake inhibitors, ovulation inhibition, oral contraceptives, GnRH agonist, danazol, estradiol, oophorectomy, sex steroids, cognitive behavioral therapy, calcium supplementation, Vitex agnus-castus, complementary and alternative medicine, diagnosis and classification
MeSH terms: Female, Group Processes, Humans, Premenstrual Syndrome, United States

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