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Cited by 56Maternal Mental Health During Pregnancy and PostpartumObsessive-Compulsive Spectrum DisordersPsychoanalysis and Psychopathology Research

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Obsessive-compulsive disorder in pregnancy and the postpartum period: course of illness and obstetrical outcome

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House, Samuel J., Tripathi, Shanti P., Knight, Bettina T., Morris, Natalie, Newport, D. Jeffrey, Stowe, Zachary N.·2016·Archives of Women's Mental Health
DOI 10.1007/s00737-015-0542-zPMC PMC4715787
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Abstract

The study aimed to examine the course of obsessive-compulsive disorder (OCD) across pregnancy and its impact on obstetric and neonatal outcomes. Women enrolled prior to 20-week gestation in a prospective, observational study. The Structured Clinical Interview for DSM-IV was completed to obtain lifetime Axis I diagnoses. A total of 56 women with OCD were followed at 1 to 3-month intervals through 52 weeks postpartum. Each visit, the Yale-Brown Obsessive Compulsive Scale (YBOCS), clinical assessment, and medication/exposure tracking were performed. Obstetric and neonatal data were abstracted from the medical record. In subjects with OCD, associations between perinatal obsessive-compulsive symptoms (OCSs) and outcomes were examined. Additionally, outcomes were compared to 156 matched psychiatric patients without OCD. Maternal age inversely correlated with the YBOCS scores across the study period (β = -0.5161, p = .0378). Cesarean section was associated with increased OCSs in the postpartum period compared to vaginal delivery (β = 5.3632, p = 0.043). No associations were found between severity of perinatal obsessions or compulsions and any specific obstetric or neonatal complications. Subjects without OCD had higher frequency of fetal loss compared to mothers with OCD (χ (2) = 4.03, p = 0.043). These novel prospective data fail to identify an association of OCSs with adverse outcomes. In contrast, there is an association of delivery method and younger maternal age with increased postnatal symptoms of OCD. Psychiatric subjects without OCD may have a higher risk of miscarriage and intrauterine fetal demise compared to subjects with OCD.

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  • Major transitional periods, including pregnancy and childbirth, have been associated with the onset or exacerbation of OCD symptoms.

    “As major transitional periods, including pregnancy and childbirth, have been associated with the onset or exacerbation of OCD symptoms [29]”

    From Depression, anxiety, PTSD, and OCD after stillbirth: a systematic review (2021) · cites this paper as [29]

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Research works printed but not linked: 1

  1. First M, Spitzer R, Gibbon M, et al. (2002) Structured clinical interview for DSM-IV axis I disorders - patient edition (SCID-I/P, version 2.0). Biometrics Research Department, New York State Psychiatric Institute

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Metadata

Authors
House, S. J., Tripathi, S. P., Knight, B. T., Morris, N., Newport, D. J., & Stowe, Z. N.
Affiliations
  • University of Arkansas for Medical Sciences (US)
  • University of Miami (US)
Corresponding author
House, Samuel J.
ORCID
Venue
Archives of Women's Mental Health
Publisher
Springer Science and Business Media LLC
Published
2015-07-16
Volume
19
Issue
1
Pages
3-10
ISSN
  • 1434-1816 (ISSN-L)
  • 1435-1102
DOI
10.1007/s00737-015-0542-z
PMC
PMC4715787
OpenAlex
W1569816458
Cited by
56
References
39
Citations by year
2025: 5 · 2024: 4 · 2023: 5 · 2022: 8 · 2021: 12 · 2020: 3 · 2019: 8 · 2018: 5 · 2017: 2 · 2016: 3 · 2015: 1
FWCI
3.92
Type
journal article
Language
en
Open access
Licence
www.springer.com/tdm (tdm)
Locations
  • Archives of Women s Mental Health (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (P50 MH 77928, P50MH068036, P50 MH 68036, P50MH077928)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
obsessive-compulsive disorder, pregnancy, postpartum period, obstetric outcomes, cesarean section, vaginal delivery, maternal age, fetal death, intrauterine fetal death, neonatal outcomes, clinical course
MeSH terms
Adult, Female, Humans, Obsessive-Compulsive Disorder, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Pregnancy Trimester, Second, Prospective Studies, Psychiatric Status Rating Scales, Risk Factors, Severity of Illness Index, Socioeconomic Factors, United States, Parturition, Diagnostic and Statistical Manual of Mental Disorders, Postpartum Period

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