Does methylphenidate improve academic performance? A systematic review and meta-analysis
Open accessAbstract
Academic improvement is amongst the most common treatment targets when prescribing stimulants to children with ADHD. Previous reviews on stimulant-related academic improvements are inconclusive and focus on task engagement. Recent literature suggests outcome-domain-specific medication effects that are larger for productivity than for accuracy. The aims of this study are quantifying methylphenidate effects on academic productivity and accuracy for math, reading, spelling; exploring the mediating or moderating effects of symptom improvements, demographic-, design- and disorder-related variables. PubMed, EMBASE, ERIC and PsycINFO were searched for articles reporting methylphenidate effects on academic productivity and accuracy. Thirty-four studies met entry criteria. Methylphenidate improved math productivity (7.8% increase, p < .001); math accuracy (3.0% increase, p = .001); increased reading speed (SMD .47, p < .001) but not reading accuracy. None of the mediators or moderators tested affected methylphenidate efficacy. Academic improvements were small compared to symptom improvements; qualitative changes limited to math. Clinicians should take this discrepancy into account when prescribing medication for ADHD.
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Stimulant medication improves academic seatwork productivity in analogue classrooms in children with ADHD.
“Many studies have shown that stimulants improve cognitive functioning on laboratory tasks (Coghill et al., 2014; Pietrzak et al., 2006; Rapport & Kelly, 1991; Swanson et al., 2011; Vertessen et al., 2021) and academic seatwork productivity in analogue classrooms (Fabiano et al., 2007; Kortekaas-Rijlaarsdam et al., 2019; Pelham et al., 1985; Prasad et al., 2013).”
From The effect of stimulant medication on the learning of academic curricula in children with ADHD: A randomized crossover study. (2022) · cites this paper as Kortekaas-Rijlaarsdam et al., 2019
The Introduction reports that stimulant medication improved seatwork productivity compared with placebo, and the paper’s meta-analysis reports improved math productivity in children with ADHD. The cited passages do not establish that the productivity finding specifically applies to analogue classrooms; the review covers academic tasks across studies rather than identifying that setting for the pooled result. Page numbers are unavailable in our copy. (LLM, conf=0.82)
Experimental — accuracy not yet measuredThe study improved beyond existing analogue classroom studies by using academic curricula and direct measurement of learning over an ecologically valid timeframe (a 3-week curriculum unit).
“This study improved beyond the existing analogue classroom studies (Kortekaas-Rijlaarsdam et al., 2019) via the use of academic curricula and direct measurement of learning over an ecologically valid timeframe (i.e., a 3-week curriculum unit).”
From The effect of stimulant medication on the learning of academic curricula in children with ADHD: A randomized crossover study. (2022) · cites this paper as Kortekaas-Rijlaarsdam et al., 2019
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References 63 · Cited by 99
Research works printed but not linked: 20
- Polderman TJC, Boomsma DI, Bartels M et al (2010) A system- atic review of prospective studies on attention problems and aca- demic achievement. Acta Psychiatr Scand 122:271-284. http s:// doi.org/10.1111 /j.1600 -0447 .2010 .0156 8.x · DOI · Paper page
- Frazier TW, Youngstrom EA, Glutting JJ, Watkins MW (2007) ADHD and achievement: meta-analysis of the child, adolescent, and adult literatures and a concomitant study with college stu- dents. J Learn Disabil 40:49-65. http s://doi.org/10.1177 /0022 2194 0704 0001 0401 · DOI · Paper page
- Wright N, Moldavsky M, Schneider J et al (2015) Practitioner review: pathways to care for ADHD-a systematic review of bar- riers and facilitators. J Child Psychol Psychiatry 56:598-617. http s://doi.org/10.1111 /jcpp .1239 8 · DOI
- Coghill DR, Seth S, Pedroso S et al (2013) Effects of methylphe- nidate on cognitive functions in children and adolescents with attention-deficit/hyperactivity disorder: evidence from a sys- tematic review and a meta-analysis. Biol Psychiatry. http s://doi. org/10.1016 /j.biop sych .2013 .10.005 · DOI · Paper page
- Aman MG (1980) Psychotropic drugs and learning problems: a selective review. J Learn Disabil 13(2):87-97
- Barkley RA (1977) A review of stimulant drug research with hyperactive children. J Child Psychol Psychiatry 18:137-165
- Schachar R, Tannock R (1993) Hyperactivity and psychostimu- lant: of extended treatment studies a review. J Child Adolesc Psy- chopharmacol 3:81-97
- Prasad V, Brogan E, Mulvaney C et al (2013) How effective are drug treatments for children with ADHD at improving on-task behaviour and academic achievement in the school classroom? A systematic review and meta-analysis. Eur Child Adolesc Psychia- try 22:203-216
- Arnold LE, Hodgkins P, Kahle J et al (2015) Long-term outcomes of ADHD: academic achievement and performance. J Attent Dis- ord. http s://doi.org/10.1177 /1087 0547 1456 6076 · DOI · Paper page
- Schachar R, Tannock R (1993) Childhood hyperactivity and psy- chostimulants: a review of extended treatment studies. J Child Adolesc Psychopharmacol 3:81-97
- Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6:e1000097. http s://doi. org/10.1371 /jour nal.pmed .1000 097 · DOI · Paper page
- Borenstein M, Hedges L, Higgins J, Rothstein H (2009) Introduc- tion to meta-analysis. Wiley, Chichester 35. Loney J, Milich R (1982) Hyperactivity, inattention, and aggres- sion in clinical practice. In: Wolraich M, Routh D (eds) Advances in developmental and behavioral pediatrics, vol 3. JAI Press, Greenwich, CT, pp 113-147
- Hay DA, Bennett KS, Levy F et al (2007) A twin study of attention-deficit/hyperactivity disorder dimensions rated by the strengths and weaknesses of ADHD-symptoms and normal- behavior (SWAN) scale. Biol Psychiatry 61:700-705. http s://doi. org/10.1016 /j.biop sych .2006 .04.040 · DOI
- Twisk JWR (2010) Introduction in applied biostatistics (Inleiding in de toegepaste biostatistiek). Reed Business, Amsterdam 43. Higgins JPT, Thompson SG, Deeks JJ, Altman DG (2003) Meas- uring inconsistency in meta-analyses. BMJ Br Med J 327:557- 560. http s://doi.org/10.1136 /bmj.327.7414 .557 · DOI · Paper page
- Ioannidis JPA, Patsopoulos NA, Evangelou E (2007) Uncertainty in heterogeneity estimates in meta-analyses. BMJ 335:914-916. http s://doi.org/10.1136 /bmj.3934 3.4084 49.80 · DOI · Paper page
- Gorman EB, Klorman R, Thatcher JEBA (2006) Effects of meth- ylphenidate on subtypes of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 45:808-816. http s://doi. org/10.1097 /01.chi.0000 2141 91.5799 3.dd · DOI
- Preston AS, Heaton SC, McCann SJ et al (2009) The role of mul- tidimensional attentional abilities in academic skills of children with ADHD. J Learn Disabil 42:240-249. http s://doi.org/10.1177 /0022 2194 0833 1042 · DOI
- Thorell LB (2007) Do delay aversion and executive function deficits make distinct contributions to the functional impact of ADHD symptoms? A study of early academic skill deficits. J Child Psychol Psychiatry Allied Discip 48:1061-1070. http s:// doi.org/10.1111 /j.1469 -7610 .2007 .0177 7.x · DOI · Paper page
- Biederman J, Monuteaux MC, Doyle AE et al (2004) Impact of executive function deficits and attention-deficit/hyperactivity dis- order (ADHD) on academic outcomes in children. J Consult Clin Psychol 72:757-766. http s://doi.org/10.1037 /0022 -006X .72.5.757 · DOI · Paper page
- Coghill DR, Hayward D, Rhodes SM et al (2014) A longitudi- nal examination of neuropsychological and clinical functioning in boys with attention deficit hyperactivity disorder (ADHD): improvements in executive functioning do not explain clini- cal improvement. Psychol Med 44:1087-1099. http s://doi. org/10.1017 /S003 3291 7130 0176 1 · DOI
- Authors
- Kortekaas-Rijlaarsdam, A. F., Luman, M., Sonuga-Barke, E., & Oosterlaan, J.
- Affiliations
- Vrije Universiteit Amsterdam (NL)
- King's College London (GB)
- Corresponding author
- Kortekaas-Rijlaarsdam, Anne Fleur
- Venue
- European Child & Adolescent Psychiatry
- Published
- 2018-01-20
- Volume
- 28
- Issue
- 2
- Pages
- 155-164
- ISSN
- 1018-8827 (ISSN-L)
- 1435-165X
- OpenAlex
- W2783849769
- Cited by
- 99
- References
- 63
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 13 · 2023: 9 · 2022: 16 · 2021: 17 · 2020: 14 · 2019: 9 · 2018: 6
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- European Child & Adolescent Psychiatry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Portal (King's College London) (publishedVersion, cc-by)
- Pure Amsterdam UMC (submittedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- VU Research Portal (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Shire
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Keywords
- methylphenidate, attention deficit hyperactivity disorder, academic performance, academic productivity, mathematics achievement, reading speed, spelling, stimulant medication, symptom improvement, mediating and moderating effects, children
- MeSH terms
- Academic Performance, Achievement, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Child, Educational Measurement, Female, Humans, Mathematics, Methylphenidate, Reading, Task Performance and Analysis, Outcome Assessment, Health Care
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