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Cited by 156Abdominal vascular conditions and treatmentsIntestinal and Peritoneal AdhesionsAppendicitis Diagnosis and Management

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

Acute Occlusive Mesenteric Ischemia: Surgical Management and Outcomes

Edwards, Matthew S., Cherr, Gregory S., Craven, Timothy E., Olsen, Amy W., Plonk, George W., Geary, Randolph L., Ligush, John L., Hansen, Kimberley J.·2003·Annals of Vascular Surgery
DOI 10.1007/s10016-001-0329-8
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Abstract

Acute mesenteric ischemia secondary to arterial occlusion (AMI) remains a highly lethal condition. To examine recent trends in management and associated outcomes, we examined our institutional experience over a recent 10-year period. All patients treated for AMI between January 1990 and January 2000 were identified (76 patients, 77 cases) and their medical records examined. At presentation, 64% demonstrated peritonitis and 30% exhibited hypotension. The interval from symptom onset to treatment exceeded 24 h in 63% of cases. Etiology was mesenteric thrombosis in 44 patients (58%) and embolism in 32 patients (42%). Thirty-five patients (46%) had prior conditions placing them at high risk for the development of AMI including chronic mesenteric ischemia (n = 26) and inadequately anticoagulated chronic atrial fibrillation (n = 9). Surgical management consisted of exploration alone in 16 patients, bowel resection alone in 18 patients, and revascularization in 43 patients, including 28 who required concomitant bowel resection. Overall, intestinal necrosis was present in 81% of cases. Perioperative mortality was 62% and long-term parenteral nutrition (TPN) was required in 31% of survivors. Peritonitis (odds ratio [OR] 9.4, 95% confidence interval [CI] 1.6, 54.0; p = 0.012 and bowel necrosis (OR 10.4, CI 1.9, 56.3; p = 0.007) at presentation were independent predictors of death or survival dependent upon TPN. We conclude that AMI remains a highly lethal condition due in large part to advanced presentation and inadequate recognition and treatment of patients at high risk.

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Crossref · 10.1007/s10016-001-0329-8

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Metadata

Authors
Edwards, M. S., Cherr, G. S., Craven, T. E., Olsen, A. W., Plonk, G. W., Geary, R. L., Ligush, J. L., & Hansen, K. J.
Affiliations
Wake Forest University Health Sciences (US)
Corresponding author
Hansen, Kimberley J.
ORCID
Venue
Annals of Vascular Surgery
Publisher
Elsevier BV
Published
2003-01
Volume
17
Issue
1
Pages
72-79
ISSN
0890-5096 (ISSN-L)
DOI
10.1007/s10016-001-0329-8
OpenAlex
W2147715732
Cited by
156
References
29
Citations by year
2026: 1 · 2025: 3 · 2024: 1 · 2023: 3 · 2022: 6 · 2021: 5 · 2020: 5 · 2019: 6 · 2018: 6 · 2017: 5 · 2016: 8 · 2015: 6 · 2014: 10 · 2013: 6 · 2012: 12
FWCI
8.79
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Annals of Vascular Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
  • Health Sciences › Medicine › Surgery › Intestinal and Peritoneal Adhesions
  • Health Sciences › Medicine › Emergency Medicine › Appendicitis Diagnosis and Management
Keywords
acute mesenteric ischemia, arterial occlusion, mesenteric thrombosis, mesenteric embolism, bowel resection, mesenteric revascularization, intestinal necrosis, peritonitis, atrial fibrillation, anticoagulation, parenteral nutrition, perioperative mortality, mortality risk factors
MeSH terms
Adult, Aged, Embolism, Female, Humans, Male, Mesenteric Arteries, Mesenteric Vascular Occlusion, Middle Aged, Morbidity, Peritonitis, Retrospective Studies, Thrombosis, Vascular Surgical Procedures, Logistic Models, Treatment Outcome

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