The DOI matches its Crossref record; 155 of the 155 references it cites were found in a registry or an index.
Candida glabrata: a review of its features and resistance
Open accessAbstract
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections. Once believed to be non-pathogenic, Candida glabrata was rapidly blamable for many human diseases. Year after year, these pathological circumstances are more recurrent and problematic to treat, especially when patients reveal any level of immunosuppression. These difficulties arise from the capacity of C. glabrata to form biofilms and also from its high resistance to traditional antifungal therapies. Thus, this review intends to present an excerpt of the biology, epidemiology, and pathology of C. glabrata, and detail an approach to its resistance mechanisms based on studies carried out up to the present.
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In the citing paper
“The first step of C. glabrata biofilm development is adhesion and/or colonisation of yeast cells to an abiotic or/and biotic surface [4,10].”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [10]
In the citing paper
“In addition to the high antifungal drugs resistance and inability to form hyphae or secret hydrolases, C. glabrata retain many virulence factors”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [10]
In the citing paper
“C. glabrata retain many virulence factors that contribute to its extreme aggressiveness and result in a low therapeutic response and serious recurrent candidiasis”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [10]
In the citing paper
“For their extraordinary organization, especially regarding the complex structure of the matrix, biofilms are very resistant to antifungal treatments.”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [10]
In the citing paper
“particularly biofilm formation ability”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [10]
Citations
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Mechanisms of biofilm resistance to antimicrobial agents
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Cited by
Sorted by citations
Candida sp. Infections in Patients with Diabetes Mellitus
Rodrigues, C. F., Rodrigues, M. E., & Henriques, M. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8010076 · Cited by 350
Self-citationYeast diversity of sourdoughs and associated metabolic properties and functionalities
Vuyst, L. D., Harth, H., Kerrebroeck, S. V., & Leroy, F. (2016) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2016.07.018 · Cited by 306
Candida Species Biofilms’ Antifungal Resistance
Silva, S. M., Rodrigues, C. F., Araújo, D., Rodrigues, M. E., & Henriques, M. (2017) · Journal of Fungi · doi:10.3390/jof3010008 · Cited by 317
Self-citationGeddes‐McAlister, J., & Shapiro, R. S. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13739 · Cited by 162
Drug-Resistant Candida glabrata Infection in Cancer Patients
Farmakiotis, D., Tarrand, J. J., & Kontoyiannis, D. P. (2014) · Emerging Infectious Diseases · doi:10.3201/eid2011.140685 · Cited by 152
Metadata
- Authors
- Rodrigues, C. F., Silva, S., & Henriques, M.
- Affiliations
- Institute for Biotechnology and Bioengineering (PT)
- Corresponding author
- Henriques, M.
- Venue
- European Journal of Clinical Microbiology & Infectious Diseases
- Published
- 2013-11-19
- Volume
- 33
- Issue
- 5
- Pages
- 673-688
- ISSN
- 0934-9723 (ISSN-L)
- 1435-4373
- OpenAlex
- W2099290964
- Cited by
- 268
- References
- 155
- Citations by year
- 2026: 11 · 2025: 10 · 2024: 23 · 2023: 17 · 2022: 25 · 2021: 28 · 2020: 27 · 2019: 24 · 2018: 34 · 2017: 24 · 2016: 19 · 2015: 16 · 2014: 10
- FWCI
- 1.95
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- other-oa
- www.springer.com/tdm (tdm)
- Locations
- European Journal of Clinical Microbiology & Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
- Keywords
- Candida glabrata, antifungal resistance, biofilm, candidiasis, bloodstream infection, immunosuppression, fungal pathogenesis, yeast biology
- MeSH terms
- Antifungal Agents, Candidiasis, Humans, Drug Resistance, Fungal, Candida glabrata
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