Plasmid-mediated quinolone resistance: an update

Characterization of class 1 integrons and gene cassettes in clinical isolates of Klebsiella pneumoniae from Taiwan

Chang, C., Fang, Y.-T., Tsai, S., et al. (2009) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.06.005 · Cited by 32

Changes in aac(6 ′ )-Ib-cr Prevalence and Fluoroquinolone Resistance in Nosocomial Isolates of Escherichia coli Collected from 1991 through 2005

Warburg, G., Korem, M., Robicsek, A. A., et al. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01300-08 · Cited by 31

Investigation of Plasmid-Mediated Quinolone Resistance among Isolates Obtained in a Turkish Intensive Care Unit

Nazik, H., Öngen, B., & Kuvat, N. (2008) · Japanese Journal of Infectious Diseases · doi:10.7883/yoken.jjid.2008.310 · Cited by 30

Occurrence of qnr-positive clinical isolates in Klebsiella pneumoniae producing ESBL or AmpC-type β-lactamase from five pediatric hospitals in China

Wang, A., Yang, Y., Lu, Q., et al. (2008) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2008.01163.x · Cited by 30

Emergence of the Plasmid-Mediated Quinolone Resistance Gene qnrS1 in Escherichia coli Isolates in Greece

Vasilaki, O., Ntokou, E., Ikonomidis, A., et al. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00325-08 · Cited by 30

Decreased quinolone susceptibility in high percentage of Enterobacter cloacae clinical isolates caused only by Qnr determinants

Zhao, X. P., Xu, X., Zhu, D., et al. (2010) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.12.018 · Cited by 30

qnrA Prevalence in Extended-Spectrum β-Lactamase-Positive Enterobacteriaceae Isolates from Turkey

Öktem, İ. M. A., Gülay, Z., Biçmen, M., et al. (2008) · Japanese Journal of Infectious Diseases · doi:10.7883/yoken.jjid.2008.13 · Cited by 30

Smaqnr, a new chromosome-encoded quinolone resistance determinant in Serratia marcescens

Velasco, C., Rodríguez-Martínez, J. M., Briales, A., et al. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp424 · Cited by 29

Review of the in vitro activity of gemifloxacin against Gram-positive and Gram-negative anaerobic pathogens

Goldstein, E. J. C. (2000) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/45.suppl_3.55 · Cited by 29

Coexistence of qnrB4 and qnrS1 in a clinical strain of Klebsiella pneumoniae

Fu-pin, Hu, Xiaogang, et al. (2008) · 中国药理学报：英文版 · Cited by 29

Plasmid-mediated quinolone resistance due to qnrB5 and qnrS1 genes in Salmonella enterica serovars Newport, Hadar and Saintpaul isolated from turkey meat in Denmark

Cavaco, L. M., Korsgaard, H. B., Sørensen, G., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn211 · Cited by 28

Ciprofloxacin-Resistant Enterobacteria Harboring the aac(6 ′ )-Ib-cr Variant Isolated from Feces of Inpatients in an Intensive Care Unit in Uruguay

Cordeiro, N. F., Robino, L., Medina, J., et al. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00444-07 · Cited by 28

Plasmid-mediated quinolone resistance in nalidixic-acid-susceptible strains of Salmonella enterica isolated in Scotland

Murray, A., Mather, H., Coia, J. E., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn340 · Cited by 28

Antibiotic Resistance Mechanisms of Escherichia coli Isolates from Urinary Specimens

Song, S., Lee, E. Y., Koh, E.-M., Ha, H. S., Jeong, H. J., Bae, I. K., & Jeong, S. H. (2009) · Annals of Laboratory Medicine · doi:10.3343/kjlm.2009.29.1.17 · Cited by 26

Prevalence of the Extended-Spectrum β-Lactamase and qnr Genes in Clinical Isolates of Escherichia coli

Park, Y., Kang, H., Bae, I. K., Kim, J., Kim, J., Uh, Y., Jeong, S. H., & Lee, K. (2009) · Annals of Laboratory Medicine · doi:10.3343/kjlm.2009.29.3.218 · Cited by 26

Characterisation of integrons containing the plasmid-mediated quinolone resistance gene qnrA1 in Klebsiella pneumoniae

Rodríguez-Martínez, J. M., Velasco, C., Garcı́a, I., et al. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.02.003 · Cited by 25

High Prevalence of the aac(6′)-Ib-cr Gene and Its Dissemination among Enterobacteriaceae Isolates by CTX-M-15 Plasmids in Bulgaria

Sabtcheva, S., Kaku, M., Saga, T., et al. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00584-08 · Cited by 25

Detection and genetic characterisation of qnrB in hospital isolates of Klebsiella pneumoniae in Singapore

Teo, J. W. P., Ng, K. Y., & Lin, R. T. P. (2008) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2008.08.019 · Cited by 24

First detection of plasmid-mediated, quinolone resistance determinants qnrA, qnrB, qnrS and aac(6')-Ib-cr in extended-spectrum -lactamase (ESBL)-producing Enterobacteriaceae in Budapest, Hungary

Szabó, D., Kocsis, B., Rókusz, L., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn206 · Cited by 24

Increase in hospital-acquired bloodstream infections caused by extended spectrum β-lactamase-producing Escherichia coli in a large French teaching hospital

Drieux, L., Brossier, F., Duquesnoy, O., Aubry, A., Robert, J., Sougakoff, W., Lecsö‐Bornet, M., & Jarlier, V. (2008) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-008-0656-6 · Cited by 23

Two chromosomally located qnrB variants, qnrB6 and the new qnrB16, in Citrobacter spp. isolates causing bacteraemia

Sánchez‐Céspedes, J., Martí, S., Soto, S. M., et al. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2009.02744.x · Cited by 22

Effects of a plasmid-encoded qnrA1 determinant in Escherichia coli strains carrying chromosomal mutations in the acrAB efflux pump genes

Jeong, J., Kim, E. S., Choi, S., et al. (2007) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2007.07.015 · Cited by 22

Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Patients with Overseas Travelers' Diarrhea in Japan

Taguchi, M., Kawahara, R., Seto, K., et al. (2009) · Japanese Journal of Infectious Diseases · doi:10.7883/yoken.jjid.2009.312 · Cited by 21

Evidence for qnrB1 and aac(6′)-Ib-cr in CTX-M-15–producing uropathogenic Enterobacteriaceae in an Italian teaching hospital

Perilli, M., Forcella, C., Celenza, G., et al. (2009) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.01.009 · Cited by 20

Plasmid-mediated QnrS2 determinant in an Aeromonas caviae isolate recovered from a patient with diarrhoea

Arias, A., Seral, C., Navarro, F., et al. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2009.02958.x · Cited by 19

Plasmid-mediated quinolone resistance genes in Enterobacteriaceae isolates associated with community and nosocomial urinary tract infection in East London, UK

Amin, A. K., & Wareham, D. W. (2009) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2009.01.003 · Cited by 19

Nosocomial spread of ESBL-positive Enterobacter cloacae co-expressing plasmid-mediated quinolone resistance Qnr determinants in one hospital in France

Potron, A., Poirel, L., Bernabeu, S., et al. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp222 · Cited by 19

Plasmid-mediated Quinolone Resistance Determinants in Urinary Isolates of Escherichia coli and Klebsiella pneumoniae in a Large Singapore Hospital

Deepak, R. N., Koh, T. H., & Chan, K. S. (2009) · Annals of the Academy of Medicine Singapore · doi:10.47102/annals-acadmedsg.v38n12p1070 · Cited by 18

In-vitro mutagenesis of qnrA and qnrS genes and quinolone resistance in Escherichia coli

Cattoir, V., Poirel, L., & Nordmann, P. (2007) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2007.01778.x · Cited by 17

First Detection of Plasmid-Encoded bla OXY β-Lactamase

González‐López, J. J., Coelho, A., Larrosa, N., et al. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01473-08 · Cited by 17

Detection of qnr genes in Salmonella isolated from humans in Denmark

Torpdahl, M., Hammerum, A. M., Zachariasen, C., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn492 · Cited by 17

Novel genetic environment of qnrB2 associated with TEM-1 and SHV-12 on pB1004, an IncHI2 plasmid, in Salmonella Bredeney BB1047 from Spain

Gutiérrez‐Gutiérrez, B., Herrera-Leon, S., Escudero, J. A., et al. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp340 · Cited by 17

Prevalence of qnr determinants among extended-spectrum β-lactamase-positive Enterobacteriaceae clinical isolates in southern Stockholm, Sweden

Fang, H., Huang, H., Shi, Y., et al. (2009) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2009.03.016 · Cited by 16

Plasmid-mediated quinolone resistance in Salmonella from South Africa

Govender, N., Smith, A. M., Karstaedt, A., et al. (2009) · Journal of Medical Microbiology · doi:10.1099/jmm.0.009621-0 · Cited by 15

Spread of Serratia marcescens Coharboring aac(6′)-Ib-cr , bla CTX-M , armA, and bla OXA-1 Carried by Conjugative IncL/M Type Plasmid in Korean Hospitals

Park, Y.-J., Kim, S., Yu, J. K., et al. (2009) · Microbial Drug Resistance · doi:10.1089/mdr.2009.0867 · Cited by 15

Investigation of qnr and aac(6′)-Ib-cr in Enterobacter cloacae isolates from Anhui Province, China

Xiong, Z., Wang, P., Wei, Y., et al. (2008) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2008.07.010 · Cited by 14

Persistent isolation of Salmonella Concord harbouring CTX-M-15, SHV-12 and QnrA1 in an asymptomatic adopted Ethiopian child in Spain also colonized with CTX-M-14- and QnrB-producing Enterobacteriaceae

Morosini, M.-I., Valverde, A., García-Castillo, M., et al. (2010) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkq168 · Cited by 13

Emergence of plasmid-mediated quinolone resistance genes in Enterobacteriaceae isolated from chickens in China

Wu, C., Wang, Y., Cao, X.-Y., Lin, J.-C., Qin, S., Mi, T., Huang, S.-Y., & Shen, J. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn487 · Cited by 13

Isolation and molecular characterization of multidrug-resistant Gram-negative bacteria from imported flamingos in Japan

Sato, M., Ahmed, A. M., Noda, A., Watanabe, H., Fukumoto, Y., & Shimamoto, T. (2009) · Acta veterinaria Scandinavica · doi:10.1186/1751-0147-51-46 · Cited by 13

Evaluation of antimicrobial susceptibility of bacteria containing the qnr gene and FOX-5 β-lactamase by four automated systems

Rodríguez-Martínez, J. M., Conejo, M. C., Martı́nez-Martı́nez, L., et al. (2005) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2005.01097.x · Cited by 12

Evaluation of Three Automated Systems for Susceptibility Testing of Enterobacteria Containing qnrB, qnrS, and/or aac(6′)-Ib-cr

Calvo, J., Cano, M. E., Pitart, C., Marco, F., Rodríguez-Martínez, J. M., Pascual, Á., & Martı́nez-Martı́nez, L. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.00563-11 · Cited by 10

First detection of plasmid-mediated quinolone resistance in the community setting and in hospitalized patients in Switzerland

Liassine, N., Zulueta-Rodriguez, P., Corbel, C., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn295 · Cited by 10

Identification of the qnr family in Enterobacteriaceae in clinical practice

Naqvi, S. M., Jenkins, C., McHugh, T. D., et al. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp011 · Cited by 9

Aquatic environment contamination with an epidemic Escherichia coli clone harbouring blaCTX-M-15, blaOXA-1, blaTEM-1, and aac(6)-Ib-cr in Portugal

Machado, E., Rocha, J., Coque, T., Cantón, R., Sousa, J. C., Sousa, H., & Peixe, L. (2008) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · Cited by 8

[Ciprofloxacin resistance in gram negative bacilli. Epidemiologic aspects].

Martı́nez-Martı́nez, L., Suárez, A. I., Carranza, R., et al. (1993) · PubMed · Cited by 6

Identification of plasmid-mediated quinolone resistance qnr-like genes in Romanian clinical isolates of Escherichia coli and Klebsiella pneumoniae.

Usein, C.-R., Palade, A.-M., Tatu-Chiţoiu, D., et al. (2009) · PubMed · Cited by 5

Vitek2® system: a reliable tool to detect qnr determinants in Enterobacteriaceae without quinolone resistance-determining region modifications

Corvec, S., Crémet, L., Reynaud, A., et al. (2009) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.03.026 · Cited by 5

Hidden qnrB12 gene in a Finnish faecal microbiota isolate from 1994

Gunell, M., Hakanen, A., Jalava, J., et al. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp304 · Cited by 5

Prevalence of plasmid-mediated quinolone resistance in Norwegian and Swedish clinical isolates of Escherchia coli and Klebsiella spp.

Karah, N. (2008) · NORA - Norwegian Open Research Archives · Cited by 4

First Report of Ciprofloxacin Resistance amongKlebsiella pneumoniaeHarbouring the qnrA1 Gene and Producing SHV-5 Extended-Spectrum β-lactamase in Scotland

Hamouda, A., Vali, L., Alsultan, A. A., et al. (2008) · Journal of Chemotherapy · doi:10.1179/joc.2008.20.6.753 · Cited by 4

Plasmid-mediated fluoroquinolone resistance genes identified in multidrug-resistant "Enterobacter" spp. isolated from opportunistic infections in dogs

Moss, S. M., Gibson, J. S., Cobbold, R. N., et al. (2008) · Cited by 3

Ten Years Resistance Monitoring in Avian Salmonella (S) from Two EU Regions

de Jong, A. (2008) · 46th Annual Meeting · Cited by 3

First Detection of qnr Genes in Uruguay

Gutkind, G. (2008) · 46th Annual Meeting · Cited by 3

First Description of Klebsiella pneumoniae Isolates Carrying Both qnrA and qnrB Genes in Aveiro, Portugal

Ferreira, S. (2008) · 46th Annual Meeting · Cited by 3

Screening of Plasmid-Mediated Quinolone Resistant (pfqr) Determinants in Esbl-Producing (esbl-p) and Kpc-Producing Klebsiella Pneumonia ( Kpc Kpn ) Isolates from Israel

Chmelnitsky, I. (2008) · 46th Annual Meeting · Cited by 2

Prevalence of Plasmid-Mediated Quinolone Resistance Genes Over a Nine-Year Period

Kim, H. B. (2008) · 46th Annual Meeting · Cited by 2

Plasmid-Mediated Quinolone Resistance Genes and Dissemination of Fluoroquinolone Resistance in Commensal Escherichia coli from Children Living in Bolivia and Peru

Pallecchi, L., Bartoloni, A., E, M. A. R., et al. (2008) · Use Siena air (University of Siena) · Cited by 2

Prevalence of aac(6 )-Ib-cr gene in Escherichia coli isolated in northern Italy from patients with urinary tract infections

Musumeci, R., Galimberti, V., Careddu, A., et al. (2008) · BOA (University of Milano-Bicocca) · Cited by 2

Plasmid-mediated quinolone resistance in Salmonella isolates from different sources of Portugal

Antunes, P., Matias, R., & Peixe, L. (2009) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · Cited by 2

Evaluation of Three Automated Systems for Susceptibility Testing of Enterobacteria Containing qnrB , qnrS and/or aac(6')Ib-cr Genes

Calvo, J. H. (2008) · 46th Annual Meeting · Cited by 1

Mechanisms of Antibiotic Resistance

Munita, J. M., & Arias, C. A. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.vmbf-0016-2015 · Cited by 2,782

Mechanism of Quinolone Action and Resistance

Aldred, K. J., Kerns, R. J., & Osheroff, N. (2014) · Biochemistry · doi:10.1021/bi5000564 · Cited by 1,282

Mechanisms of antibiotic resistance

Munita, J. M., & Arias, C. A. (2016) · Virulence Mechanisms of Bacterial Pathogens · doi:10.1128/9781555819286.ch17 · Cited by 421

Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria

Skepper, C. K., Armstrong, D., Balibar, C. J., Bauer, D., Bellamacina, C. R., Benton, B. M., Bussiere, D. E., Pascale, G. D., de Vicente, J., Dean, C. R., et al. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.0c00347 · Cited by 39

Conjugation between quinolone-susceptible bacteria can generate mutations in the quinolone resistance-determining region, inducing quinolone resistance

Pitondo‐Silva, A., Martins, V. V., da Silva, C. F., et al. (2014) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2014.07.018 · Cited by 13

Non-Quinolone Inhibitors of the Bacterial DNA Gyrase

Badshah, S. L., & Noreen, N. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820472-6.00177-8

Mechanism of quinolone mutagenicity in bacteria

Gocke, E. (1991) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(91)90095-6 · Cited by 59

Interaction of the Plasmid-Encoded Quinolone Resistance Protein QnrA with Escherichia coli Topoisomerase IV

Tran, J. H., Jacoby, G. A., & Hooper, D. C. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.7.3050-3052.2005 · Cited by 167