The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
DNA methylation profiles in cancer diagnosis and therapeutics
Open accessAbstract
Cancer initiation and proliferation is regulated by both epigenetic and genetic events with epigenetic modifications being increasingly identified as important targets for cancer research. DNA methylation catalyzed by DNA methyltransferases (DNMTs) is one of the essential epigenetic mechanisms that control cell proliferation, apoptosis, differentiation, cell cycle, and transformation in eukaryotes. Recent progress in epigenetics revealed a deeper understanding of the mechanisms of tumorigenesis and provided biomarkers for early detection, diagnosis, and prognosis in cancer patients. Although DNA methylation biomarker possesses potential contributing to precision medicine, there are still limitations to be overcome before it reaches clinical setting. Hence, the current status of DNA methylation biomarkers was reviewed and the future use in clinic was also predicted.
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1 retracted
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Cited by
Vasanthakumar, A., Davis, J. W., Idler, K., Waring, J. F., Asque, E., Riley-Gillis, B., Grosskurth, S., Srivastava, G., Kim, S., Nho, K., et al. (2020) · Clinical Epigenetics · doi:10.1186/s13148-020-00864-y · Cited by 98
Stress and coping in women with breast cancer:unravelling the mechanisms to improve resilience
Borgi, M., Collacchi, B., Ortona, E., & Cirulli, F. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.10.011 · Cited by 90
Recent advances of nucleic acid-based cancer biomarkers and biosensors
Zhao, J., Xia, K., He, P., Wei, G., Zhou, X., & Zhang, X. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215456 · Cited by 44
A Systematic Pan-Cancer Analysis of CASP3 as a Potential Target for Immunotherapy
Zhou, Z., Xu, S., Jiang, L., Tan, Z., & Wang, J. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.776808 · Cited by 36
Metadata
- Authors
- Pan, Y., Liu, G., Zhou, F., Su, B., & Li, Y.
- Venue
- Clinical and Experimental Medicine
- Published
- 2017-07-27
- Volume
- 18
- Issue
- 1
- Pages
- 1-14
- ISSN
- 1591-8890 (ISSN-L)
- 1591-9528
- OpenAlex
- W2740523213
- Cited by
- 373
- References
- 147
- FWCI
- 9.22
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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