Cited by 83HIV, Drug Use, Sexual RiskSubstance Abuse Treatment and OutcomesHIV/AIDS Research and Interventions

Hazardous and harmful use of alcohol and/or other drugs and health status among South African patients attending hiv clinics

Kader, R., Seedat, S., Govender, R., Koch, J. R., Parry, C. D.·2014·AIDS and Behavior

Abstract

There is growing recognition of the influence of substance use, particularly alcohol use, on HIV disease progression. This study investigated how hazardous/harmful use of alcohol and drugs impacts the health status of 1503 patients attending HIV clinics. Of the sample, 37 % indicated hazardous/harmful drinking and 13 % indicated a drug problem. Hazardous/harmful use of alcohol and drugs was significantly related to health status, with participants using substances more likely to have TB-positive status (χ(2) = 4.30, p < 0.05), less likely to be on ARVs (χ(2) = 9.87, p < 0.05) and having lower CD4 counts (t = 4.01, p < 0.05). Structural equation modelling confirmed the centrality of hazardous/harmful use of alcohol as a direct and indirect determinant of disease progression. Based on these findings it is recommended that patients attending HIV clinics be routinely screened for problematic alcohol and/or drug use, with strong emphasis on ensuring ARV adherence in those with problematic alcohol use.

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Crossref · 10.1007/s10461-013-0587-9

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Authors
Kader, R., Seedat, S., Govender, R., Koch, J. R., & Parry, C. D.
Corresponding author
Kader, R.
Venue
AIDS and Behavior
Published
2013-08-07
Volume
18
Issue
3
Pages
525-534
ISSN
  • 1090-7165 (ISSN-L)
  • 1573-3254
OpenAlex
W2055747888
Cited by
83
References
29
Citations by year
2026: 2 · 2025: 6 · 2024: 12 · 2023: 3 · 2022: 12 · 2021: 7 · 2020: 7 · 2019: 6 · 2018: 6 · 2017: 8 · 2016: 6 · 2015: 2 · 2014: 5 · 2013: 1
FWCI
3.40
Type
journal article
Language
en
Open access
closed
Locations
  • AIDS and Behavior (publishedVersion)
  • PubMed (publishedVersion)
  • Open University of Cape Town (University of Cape Town) (submittedVersion)
Funders
  • U.S. President’s Emergency Plan for AIDS Relief
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
  • Centers for Disease Control and Prevention
  • U.S. Public Health Service (5U2GPS001137)
Topics
  • Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Keywords
hazardous drinking, HIV, substance use, HIV disease progression, tuberculosis, antiretroviral therapy adherence, CD4 count, health status, screening, South Africa
MeSH terms
Adult, Aged, Alcohol Drinking, Alcoholism, Cross-Sectional Studies, Female, Health Status, Humans, Male, Regression Analysis, Risk, Socioeconomic Factors, South Africa, Urban Population, HIV Infections, Prevalence, CD4 Lymphocyte Count, Anti-HIV Agents, Viral Load, Substance-Related Disorders

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