Association of Syndemic Unhealthy Alcohol Use, Smoking, and Depressive Symptoms on Incident Cardiovascular Disease among Veterans With and Without HIV-Infection
Open accessAbstract
Unhealthy alcohol use, smoking, and depressive symptoms are risk factors for cardiovascular disease (CVD). Little is known about their co-occurrence - termed a syndemic, defined as the synergistic effect of two or more conditions-on CVD risk in people with HIV (PWH). We used data from 5621 CVD-free participants (51% PWH) in the Veteran's Aging Cohort Study-8, a prospective, observational study of veterans followed from 2002 to 2014 to assess the association between this syndemic and incident CVD by HIV status. Diagnostic codes identified cases of CVD (acute myocardial infarction, stroke, heart failure, peripheral artery disease, and coronary revascularization). Validated measures of alcohol use, smoking, and depressive symptoms were used. Baseline number of syndemic conditions was categorized (0, 1, ≥ 2 conditions). Multivariable Cox Proportional Hazards regressions estimated risk of the syndemic (≥ 2 conditions) on incident CVD by HIV-status. There were 1149 cases of incident CVD (52% PWH) during the follow-up (median 10.1 years). Of the total sample, 64% met our syndemic definition. The syndemic was associated with greater risk for incident CVD among PWH (Hazard Ratio [HR] 1.87 [1.47-2.38], p < 0.001) and HIV-negative veterans (HR 1.70 [1.35-2.13], p < 0.001), compared to HIV-negative with zero conditions. Among those with the syndemic, CVD risk was not statistically significantly higher among PWH vs. HIV-negative (HR 1.10 [0.89, 1.37], p = .38). Given the high prevalence of this syndemic combined with excess risk of CVD, these findings support linked-screening and treatment efforts.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
One hypothesized reason for the mixed success of alcohol interventions in the HIV literature is an increasingly recognized syndemic of co-occurring unhealthy alcohol use and other mental health-related problems among people with HIV.
“One hypothesized reason for the mixed success of alcohol interventions in the HIV literature is an increasingly recognized syndemic of co-occurring unhealthy alcohol use and other mental health-related problems among PWH [20, 21].”
From A Randomized Feasibility/Acceptability Trial of Acceptance and Commitment Therapy for People with HIV Who Drink at Unhealthy Levels. (2026) · cites this paper as [21]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.11.006 · Cited by 6,616 · see citing works
The Patient Health Questionnaire-2: Validity of a Two-Item Depression Screener
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2003) · Medical Care · doi:10.1097/01.mlr.0000093487.78664.3c · Cited by 6,359 · see citing works
Bush, K. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.16.1789 · Cited by 6,196 · see citing works
Lloyd-Jones, D. M., Hong, Y., Labarthe, D., Mozaffarian, D., Appel, L. J., Van Horn, L., Greenlund, K., Daniels, S., Nichol, G., Tomaselli, G. F., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192703 · Cited by 4,750 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000066 · Cited by 4,347 · see citing works
AUDIT‐C as a Brief Screen for Alcohol Misuse in Primary Care
Bradley, K. A., Rubinsky, A. D., Volk, R. J., Williams, E. C., Frank, D., & Kivlahan, D. R. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00403.x · Cited by 1,634 · see citing works
PRACTICE GUIDELINE FOR THE Treatment of Patients With Major Depressive Disorder
Gelenberg, A. J., Freeman, P. B., Markowitz, J. C., Rosenbaum, J. F., Thase, M. E., Trivedi, M. H., & Rhoads, R. S. (2010) · Cited by 1,372 · see citing works
HIV Infection and the Risk of Acute Myocardial Infarction
Freiberg, M. S., Chang, C.-C. H., Kuller, L. H., Skanderson, M., Lowy, E., Kraemer, K. L., Butt, A. A., Goetz, M. B., Leaf, D. A., Oursler, K. A., et al. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.3728 · Cited by 1,340 · see citing works
Self-citationWang, P. S., Berglund, P., Olfson, M., Pincus, H. A., Wells, K. B., & Kessler, R. C. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.603 · Cited by 1,325 · see citing works
Bing, E. G., Burnam, M. A., Longshore, D., Fleishman, J. A., Sherbourne, C. D., London, A. S., Turner, B. J., Eggan, F., Beckman, R., Vitiello, B., et al. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.8.721 · Cited by 1,255 · see citing works
Meta-Analysis of the Relationship Between HIV Infection and Risk for Depressive Disorders
Ciesla, J. A., & Roberts, J. E. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.5.725 · Cited by 1,106 · see citing works
McNeill, A. M., Rosamond, W. D., Girman, C. J., Golden, S. H., Schmidt, M. I., East, H. E., Ballantyne, C. M., & HEISS, G. M. (2005) · Diabetes Care · doi:10.2337/diacare.28.2.385 · Cited by 1,051 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Himmelfarb, C. D., DePalma, S. M., Gidding, S. S., Jamerson, K., Jones, D. W., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000597 · Cited by 989 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Himmelfarb, C. D., DePalma, S. M., Gidding, S. S., Jamerson, K., Jones, D. W., et al. (2018) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2018.06.010 · Cited by 947 · see citing works
Nutritional anaemias. Report of a WHO scientific group.
(1968) · PubMed · Cited by 941 · see citing works
Smith, C. J., Ryom, L., Weber, R. K., Morlat, P., Pradier, C., Reiss, P., Kowalska, J. D., Wit, S. D., Law, M. G., El-Sadr, W. M., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60604-8 · Cited by 930 · see citing works
Role of Insulin Resistance in Human Disease (Syndrome X): An Expanded Definition
Reaven, G. M. (1993) · Annual Review of Medicine · doi:10.1146/annurev.me.44.020193.001005 · Cited by 908 · see citing works
ALCOHOL AND MORTALITY IN BRITISH MEN: EXPLAINING THE U-SHAPED CURVE
Shaper, A. G., Wannamethee, G., & Walker, M. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92890-5 · Cited by 780 · see citing works
Tobacco-product use by adults and youths in the United States in 2013 and 2014
Kasza, K. A., Ambrose, B. K., Conway, K. P., Borek, N., Taylor, K., Goniewicz, M. L., Cummings, K. M., Sharma, E., Pearson, J. L., Green, V. R., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmsa1607538 · Cited by 609 · see citing works
SAUNDERS, J. B., AASLAND, O. G., AMUNDSEN, A., & GRANT, M. (1993) · Addiction · doi:10.1111/j.1360-0443.1993.tb00822.x · Cited by 480 · see citing works
Monahan, P. O., Shacham, E., Reece, M., Kroenke, K., Ong’or, W. O., Omollo, O., Yebei, V. N., & Ojwang, C. (2008) · Journal of General Internal Medicine · doi:10.1007/s11606-008-0846-z · Cited by 460 · see citing works
Koob, G. F. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_129 · Cited by 428 · cited 1× · see citing works
“Shared biological mechanisms [29, 81, 82] of these conditions support the possibility of parsimonious behavioral and pharmacologic treatment, through cognitive behavior therapy and medications such as varenicline, a partial agonist of the α4β2 nicotinic acetylcholine receptor, which has demonstrated effectiveness for…”
BackgroundValidity of diagnostic codes for acute stroke in administrative databases: a systematic review.
McCormick, N., Bhole, V., Lacaille, D., & Avina-Zubieta, J. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135834 · Cited by 414 · see citing works
Addiction is a Reward Deficit and Stress Surfeit Disorder
Koob, G. F. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00072 · Cited by 397 · see citing works
Use of Smoking-Cessation Treatments in the United States
Shiffman, S. S., Brockwell, S. E., Pillitteri, J. L., & Gitchell, J. G. (2008) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2007.09.033 · Cited by 393 · see citing works
2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment
Barua, R. S., Rigotti, N. A., Benowitz, N. L., Cummings, K. M., Jazayeri, M., Morris, P. B., Ratchford, E. V., Sarna, L., Stecker, E. C., & Wiggins, B. S. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.10.027 · Cited by 377 · see citing works
Reus, V. I., Fochtmann, L. J., Bukstein, O., Eyler, A. E., Hilty, D. M., Horvitz-Lennon, M., Mahoney, J., Pasic, J., Weaver, M., Wills, C. D., et al. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.1750101 · Cited by 372 · see citing works
A systematic review of the comorbidity between PTSD and alcohol misuse
Debell, F., Fear, N. T., Head, M., Batt-Rawden, S., Greenberg, N. L., Wessely, S. C., & Goodwin, L. (2014) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-014-0855-7 · Cited by 368 · see citing works
Us Public Health Service Clinical Practice Guideline: Treating Tobacco Use and Dependence
Fiore, M. C., & Staff, G. P. A. (2000) · Respiratory Care · doi:10.1177/002013240004501007 · Cited by 346 · see citing works
Post-traumatic stress disorder and cardiovascular disease
Edmondson, D. E., & von Känel, R. (2017) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)30377-7 · Cited by 346 · see citing works
Rollman, B. L., Belnap, B. H., LeMenager, M. S., Mazumdar, S., Houck, P. R., Counihan, P. J., Kapoor, W. N., Schulberg, H. C., & Reynolds, C. F. (2009) · JAMA · doi:10.1001/jama.2009.1670 · Cited by 343 · see citing works
Veterans Aging Cohort Study (VACS)
Justice, A. C., Dombrowski, E., Conigliaro, J. C., Fultz, S. L., Gibson, D., Madenwald, T., Goulet, J. L., Simberkoff, M. S., Butt, A. A., Rimland, D., et al. (2006) · Medical Care · doi:10.1097/01.mlr.0000223741.02074.66 · Cited by 322 · see citing works
Self-citationCROSS-CULTURAL AND ANTHROPOBIOLOGICAL REFLECTIONS ON AFRICAN UVULECTOMY
Wind, J. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92809-5 · Cited by 317 · see citing works
Koob, G. F. (2011) · Current topics in behavioral neurosciences · doi:10.1007/978-3-642-28720-6_129 · Cited by 307 · see citing works
Litten, R. Z., Ryan, M. L., Fertig, J. B., Falk, D. E., Johnson, B., Dunn, K. E., Green, A. I., Pettinati, H. M., Ciraulo, D. A., Sarid-Segal, O., et al. (2013) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e31829623f4 · Cited by 287 · see citing works
Kramer, J. R., Davila, J. A., MILLER, E. D., Richardson, P., Giordano, T. P., & EL‐SERAG, H. B. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03572.x · Cited by 269 · see citing works
Validity of myocardial infarction diagnoses in administrative databases: a systematic review.
McCormick, N., Lacaille, D., Bhole, V., & Avina-Zubieta, J. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092286 · Cited by 262 · cited 1× · see citing works
“Based on our previous work [5, 9, 10], prevalent CVD at baseline was defined by validated International Classification of Diseases, Ninth Revision (ICD-9) codes and Current Procedures Terminology (CPT) codes for acute myocardial infarction [34], ischemic stroke [35], heart failure [36], unstable angina [37], periphera…”
MethodO’Connor, E. A., Perdue, L. A., Senger, C. A., Rushkin, M., Patnode, C. D., Bean, S. I., & Jonas, D. E. (2018) · JAMA · doi:10.1001/jama.2018.12086 · Cited by 249 · see citing works
van der Burg, B., Rutteman, G. R., Blankenstein, M. A., de Laat, S. W., & van Zoelen, E. J. J. (1988) · Journal of Cellular Physiology · doi:10.1002/jcp.1041340112 · Cited by 247 · see citing works
Underdiagnosis of depression in HIV
Asch, S. M., Kilbourne, A. M., Gifford, A. L., Burnam, M. A., Turner, B. J., Shapiro, M. F., & Bozzette, S. A. (2003) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2003.20938.x · Cited by 239 · see citing works
McCormick, N., Lacaille, D. V., Bhole, V., & Aviña-Zubieta, J. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104519 · Cited by 235 · cited 1× · see citing works
“Based on our previous work [5, 9, 10], prevalent CVD at baseline was defined by validated International Classification of Diseases, Ninth Revision (ICD-9) codes and Current Procedures Terminology (CPT) codes for acute myocardial infarction [34], ischemic stroke [35], heart failure [36], unstable angina [37], periphera…”
MethodButt, A. A., Chang, C. H., Kuller, L. H., Goetz, M. B., Leaf, D. A., Rimland, D., Gibert, C. L., Oursler, K. K., Rodriguez‐Barradas, M. C., Lim, J. K., et al. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.151 · Cited by 221 · see citing works
Self-citationAertgeerts, B., Buntinx, F., Ansoms, S., & Fevery, J. (2001) · Europe PMC (PubMed Central) · Cited by 197 · see citing works
Huffman, J. C., Mastromauro, C. A., Beach, S. R., Celano, C. M., DuBois, C. M., Healy, B. C., Suarez, L., Rollman, B. L., & Januzzi, J. L. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.739 · Cited by 196 · see citing works
HIV status and the risk of ischemic stroke among men
Sico, J. J., Chang, C. H., So‐Armah, K., Justice, A. C., Hylek, E. M., Skanderson, M., McGinnis, K., Kuller, L. H., Kraemer, K. L., Rimland, D., et al. (2015) · Neurology · doi:10.1212/wnl.0000000000001560 · Cited by 184 · see citing works
Self-citationSilverberg, M. J., Leyden, W. A., Xu, L., Horberg, M. A., Chao, C., Towner, W. J., Hurley, L. B., Quesenberry, C. P., & Klein, D. B. (2013) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000009 · Cited by 179 · see citing works
Farahani, M., Mulinder, H., Farahani, A. A., & Marlink, R. (2016) · International Journal of STD & AIDS · doi:10.1177/0956462416632428 · Cited by 168 · see citing works
Hargraves, D., White, C., Frederick, R., Cinibulk, M., Peters, M., Young, A., & Elder, N. (2017) · Public Health Reviews · doi:10.1186/s40985-017-0077-0 · Cited by 161 · see citing works
Interventions and approaches to integrating HIV and mental health services: a systematic review
Chuah, F. L. H., Haldane, V. E., Cervero‐Liceras, F., Ong, S. E., Sigfrid, L., Murphy, G. A. V., Watt, N. F., Balabanova, D., Hogarth, S., Maimaris, W., et al. (2017) · Health Policy and Planning · doi:10.1093/heapol/czw169 · Cited by 160 · see citing works
Cerrato, E., D’Ascenzo, F., Biondi‐Zoccai, G., Calcagno, A., Frea, S., Marra, W. G., Castagno, D., Omedè, P. L., Quadri, G., Sciuto, F., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/ehs471 · Cited by 149 · see citing works
Cooke, C. R., Joo, M. J., Anderson, S. M., Lee, T. A., Udris, E. M., Johnson, E., & Au, D. H. (2011) · BMC Health Services Research · doi:10.1186/1472-6963-11-37 · Cited by 145 · see citing works
Lancet, T. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30640-2 · Cited by 136 · see citing works
The Depression Treatment Cascade in Primary Care: A Public Health Perspective
Pence, B. W., O’Donnell, J. K., & Gaynes, B. N. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-012-0274-y · Cited by 133 · see citing works
HIV infection and incidence of ischemic stroke
Marcus, J. L., Leyden, W. A., Chao, C., Chow, F. C., Horberg, M. A., Hurley, L. B., Klein, D. B., Quesenberry, C. P., Towner, W. J., & Silverberg, M. J. (2014) · AIDS · doi:10.1097/qad.0000000000000352 · Cited by 129 · see citing works
Risk of diabetes in HIV infected veterans pre- and post-HAART and the role of HCV coinfection†
Butt, A. A., Fultz, S. L., Kwoh, K. C., Kelley, D. E., Skanderson, M., & Justice, A. C. (2004) · Hepatology · doi:10.1002/hep.20289 · Cited by 125 · see citing works
Self-citationLongenecker, C. T., Funderburg, N., Jiang, Y., Debanne, S. M., Storer, N. J., Labbato, D. E., Lederman, M. M., & McComsey, G. (2013) · HIV Medicine · doi:10.1111/hiv.12013 · Cited by 122 · see citing works
Tsai, A. (2014) · Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000210 · Cited by 122 · see citing works
Effectiveness of Online Collaborative Care for Treating Mood and Anxiety Disorders in Primary Care
Rollman, B. L., Belnap, B. H., Abebe, K. Z., Spring, M. B., Rotondi, A. J., Rothenberger, S. D., & Karp, J. F. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.3379 · Cited by 118 · see citing works
study, F. T. C. O. A. S. U. T. (., Eyawo, O., Franco‐Villalobos, C., Hull, M., Nohpal, A., Samji, H., Sereda, P., Lima, V. D., Shoveller, J., Moore, D. M., et al. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-017-2254-7 · Cited by 114 · see citing works
Varas‐Lorenzo, C., Castellsagué, J., Stang, M. R., Tomas, L., Aguado, J., & Perez‐Gutthann, S. (2008) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1619 · Cited by 107 · see citing works
Association of Human Immunodeficiency Virus Infection and Risk of Peripheral Artery Disease
Beckman, J. A., Duncan, M. S., Alcorn, C., So‐Armah, K., Butt, A. A., Goetz, M. B., Tindle, H. A., Sico, J. J., Tracy, R. P., Justice, A. C., et al. (2018) · Circulation · doi:10.1161/circulationaha.117.032647 · Cited by 106 · see citing works
Self-citationAlcohol's effects on the risk for coronary heart disease.
Mukamal, K. J., & Rimm, E. B. (2001) · PubMed Central · Cited by 104 · see citing works
The Risk of Incident Coronary Heart Disease Among Veterans With and Without HIV and Hepatitis C
Freiberg, M. S., Chang, C. H., Skanderson, M., McGinnis, K. A., Kuller, L. H., Kraemer, K. L., Rimland, D., Goetz, M. B., Butt, A. A., Barradas, M. C. R., et al. (2011) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.110.957415 · Cited by 104 · see citing works
Self-citationHeavy Alcohol Use Is Associated With Worse Retention in HIV Care
Monroe, A. K., Lau, B. M., Mugavero, M. J., Mathews, W. C., Mayer, K. H., Napravnik, S., Hutton, H. E., Kim, H., Jabour, S. M., Moore, R. D., et al. (2016) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000001083 · Cited by 102 · see citing works
Justice, A. C., Gordon, K. S., Skanderson, M., Edelman, E. J., Akgün, K. M., Gibert, C. L., Re, V. L., Rimland, D., Womack, J. A., Wyatt, C. M., et al. (2018) · AIDS · doi:10.1097/qad.0000000000001756 · Cited by 100 · see citing works
Self-citationO’Malley, S. S., Zweben, A., Fucito, L. M., Wu, R., Piepmeier, M. E., Ockert, D. M., Bold, K. W., Petrakis, I. L., Muvvala, S. B., Jatlow, P. I., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.3544 · Cited by 94 · see citing works
A Competing Neurobehavioral Decision Systems model of SES-related health and behavioral disparities
Bickel, W. K., Moody, L., Quisenberry, A. J., Ramey, C. T., & Sheffer, C. E. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.06.032 · Cited by 88 · see citing works
Freiberg, M. S., McGinnis, K. A., Kraemer, K. L., Samet, J. H., Conigliaro, J. C., Ellison, R. C., BRYANT, K. J., Kuller, L. H., & Justice, A. C. (2010) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181c6c4b7 · Cited by 86 · see citing works
Self-citationEvarts, E. V. (1972) · Brain Research · doi:10.1016/0006-8993(72)90101-1 · Cited by 85 · see citing works
Kader, R., Seedat, S., Govender, R., Koch, J. R., & Parry, C. D. (2014) · AIDS and Behavior · doi:10.1007/s10461-013-0587-9 · Cited by 83 · see citing works
Epidemiological and clinical study of autistic children in Yogyakarta, Indonesia.
Wignyosumarto, S., Mukhlas, M., & Shirataki, S. (1992) · PubMed · Cited by 78 · see citing works
Trends in Cardiovascular Disease Mortality Among Persons With HIV in New York City, 2001–2012
Hanna, D. B., Ramaswamy, C., Kaplan, R. C., Kizer, J. R., Anastos, K., Daskalakis, D., Zimmerman, R., & Braunstein, S. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw470 · Cited by 76 · see citing works
Tobacco, illicit drugs use and risk of cardiovascular disease in patients living with HIV
Raposeiras‐Roubín, S., Abu-Assi, E., & Íñiguez, A. (2017) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000407 · Cited by 71 · see citing works
Crothers, K. A., Goulet, J. L., Rodriguez‐Barradas, M. C., Gibert, C. L., Butt, A. A., Braithwaite, R. S., Peck, R., & Justice, A. C. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-007-0158-8 · Cited by 68 · see citing works
Self-citationWhite, J. R., Chang, C. H., So‐Armah, K., Stewart, J. C., Gupta, S. K., Butt, A. A., Gibert, C. L., Rimland, D., Rodriguez‐Barradas, M. C., Leaf, D. A., et al. (2015) · Circulation · doi:10.1161/circulationaha.114.014443 · Cited by 65 · see citing works
Self-citationA Review of HIV-Specific Patient-Reported Outcome Measures
Engler, K., Lessard, D., & Lebouché, B. (2016) · Patient · doi:10.1007/s40271-016-0195-7 · Cited by 63 · see citing works
Williams, E. C., Lapham, G. T., Shortreed, S. M., Rubinsky, A. D., Bobb, J. F., Bensley, K. M., Catz, S. L., Richards, J. A., & Bradley, K. A. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.01.018 · Cited by 63 · see citing works
Tawakol, A. A., Ishai, A., Li, D., Takx, R. A. P., Hur, S., Kaiser, Y., Pampaloni, M. H., Rupert, A. W., Hsu, D. C., Sereti, I., et al. (2016) · JAMA Cardiology · doi:10.1001/jamacardio.2016.4728 · Cited by 62 · see citing works
Weaver, M. R., Conover, C. J., Proeschold‐Bell, R. J., Arno, P. S., Ang, A., & Ettner, S. L. (2008) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181642244 · Cited by 60 · see citing works
Shuter, J., Salmo, L. N., Shuter, A. D., Nivasch, E. C., Fazzari, M. J., & Moadel, A. B. (2011) · AIDS and Behavior · doi:10.1007/s10461-011-9891-4 · Cited by 51 · see citing works
Determinants of Smoking and Quitting in HIV-Infected Individuals
Regan, S., Meigs, J. B., Grinspoon, S. K., & Triant, V. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153103 · Cited by 51 · see citing works
Vagal regulation of GRP, gastric somatostatin, and gastrin secretion in vitro
Nishi, S., Seino, Y., Takemura, J., Ishida, H., Seno, M., Chiba, T., Yanaihara, C., Yanaihara, N., & Imura, H. (1985) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1985.248.4.e425 · Cited by 50 · see citing works
Marshall, B. D. L., Operario, D., BRYANT, K. J., Cook, R. L., Edelman, E. J., Gaither, J. R., Gordon, A. J., Kahler, C. W., Maisto, S. A., McGinnis, K. A., et al. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.12.023 · Cited by 48 · see citing works
Self-citationKhambaty, T., Stewart, J. C., Gupta, S. K., Chang, C.-C. H., Bedimo, R., Budoff, M. J., Butt, A. A., Crane, H. M., Gibert, C. L., Leaf, D. A., et al. (2016) · JAMA Cardiology · doi:10.1001/jamacardio.2016.2716 · Cited by 47 · see citing works
Self-citationComparing Alcohol Screening Measures Among HIV ‐Infected and ‐Uninfected Men
McGinnis, K. A., Justice, A. C., Kraemer, K. L., Saitz, R., BRYANT, K. J., & Fiellin, D. A. (2012) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2012.01937.x · Cited by 46 · see citing works
Self-citationChander, G., Monroe, A. K., Crane, H. M., Hutton, H. E., Saag, M. S., Cropsey, K. L., Eron, J. J., Quinlivan, E. B., Geng, E., Mathews, W. C., et al. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.01.015 · Cited by 46 · see citing works
Neurologic complications of cardiac transplantation.
Andrews, B. T., Hershon, J. J., CALANCHINI, P. C., Avery, G. J., & Hill, J. D. (1990) · PubMed Central · Cited by 40 · see citing works
Deiss, R. G., Mesner, O., Agan, B. K., Ganesan, A., Okulicz, J. F., Bavaro, M., Lalani, T., O'Bryan, T. A., Bebu, I., & Macalino, G. E. (2016) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.12975 · Cited by 38 · see citing works
Braithwaite, R. S., Fang, Y., Tate, J., Mentor, S. M., BRYANT, K. J., Fiellin, D. A., & Justice, A. C. (2015) · AIDS and Behavior · doi:10.1007/s10461-015-1117-8 · Cited by 37 · see citing works
Self-citationTreating smoking dependence in depressed alcoholics.
Ait‐Daoud, N., Lynch, W. J., Penberthy, J. K., Breland, A. B., Marzani-Nissen, G., & Johnson, B. A. (2006) · PubMed Central · Cited by 37 · see citing works
Chichetto, N. E., Kundu, S., Freiberg, M. S., Butt, A. A., Crystal, S., So-Armah, K. A., Cook, R. L., Braithwaite, R. S., Fiellin, D. A., Khan, M. R., et al. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz188 · Cited by 34 · see citing works
Reus, V. I., Fochtmann, L. J., Bukstein, O., Eyler, A. E., Hilty, D. M., Horvitz-Lennon, M. V., Mahoney, J., Pasic, J., Weaver, M. F., Wills, C. D., et al. (2019) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.17205 · Cited by 33 · see citing works
Davis, L. A., Mann, A., Cannon, G. W., Mikuls, T. R., Reimold, A. M., & Caplan, L. (2013) · eGEMs (Generating Evidence & Methods to improve patient outcomes) · doi:10.13063/2327-9214.1023 · Cited by 30 · cited 1× · see citing works
“, stent placement, coronary artery bypass grafting, and percutaneous coronary intervention) [39].”
BackgroundMcGinnis, K. A., Tate, J. P., Williams, E. C., Skanderson, M., BRYANT, K. J., Gordon, A. J., Kraemer, K. L., Maisto, S. A., Crystal, S., Fiellin, D. A., et al. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.09.015 · Cited by 27 · see citing works
Self-citationImportance of sulfhydryl group for rabbit gastric lipase activity
Moreau, H., Gargouri, Y., Piéroni, G., & Verger, R. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80061-9 · Cited by 24 · see citing works
Altered Expression of the D1.1 Ganglioside in the Cerebellum of the Weaver Mouse
Johnstone, S. R., & Stallcup, W. B. (1988) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1988.tb01138.x · Cited by 20 · see citing works
Pico, C., & Rocco, R. D. (1960) · BMJ · doi:10.1136/bmj.2.5194.287 · Cited by 19 · see citing works
Patient-Reported Outcomes in Cardiology
Blumenthal, D. M., Strom, J. B., Valsdottir, L. R., Howard, S. E., Wagle, N. W., Ho, K. K. L., Horn, D. M., O’Keefe, S. M., Wasfy, J. H., Metlay, J. P., et al. (2018) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.118.004794 · Cited by 17 · see citing works
Contribution of behavioral health factors to non-AIDS-related comorbidities: an updated review
Chichetto, N. E., Polanka, B. M., So-Armah, K. A., Sung, M., Stewart, J. C., Koethe, J. R., Edelman, E. J., Tindle, H. A., & Freiberg, M. S. (2020) · Current HIV/AIDS Reports · doi:10.1007/s11904-020-00498-y · Cited by 17 · see citing works
Self-citationHyperextension of the head in breech presentation
Daw, E. (1974) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(74)90222-1 · Cited by 15 · see citing works
Bali, V., Yermilov, I., Coutts, K., & Legorreta, A. P. (2015) · Vascular Medicine · doi:10.1177/1358863x15616687 · Cited by 12 · see citing works
Algur, Y., Elliott, J. C., Aharonovich, E., & Hasin, D. S. (2017) · AIDS and Behavior · doi:10.1007/s10461-017-1986-0 · Cited by 4 · see citing works
Histologic observations in normal and pathologic jejunaI biopsy specimens
ASTALDI, G. C. B. (2008) · Acta Anatomica · doi:10.1159/000143322 · Cited by 3 · see citing works
Senda, S., Izumi, H., TANIMOTO, T., & Fujimura, H. (1969) · YAKUGAKU ZASSHI · doi:10.1248/yakushi1947.89.2_254 · Cited by 3 · see citing works
Moving Beyond Cardio-Centricity in Heart Failure Risk Stratification
Borlaug, B. A. (2015) · Circulation · doi:10.1161/circulationaha.115.018951 · Cited by 2 · see citing works
[Hyperinsulinism and the coronary syndrome].
Hrnciar, J. (1992) · PubMed · Cited by 2 · see citing works
[Status, potential and expediency of legal protection regarding plasmids and vectors].
Bondarenko, N. G. (1982) · PubMed · Cited by 1 · see citing works
The role of circulating lymphocytes and lymphoid tissues in graft-versus-host reactions.
Mandel, M. A. (1971) · PubMed · Cited by 1 · see citing works
Liebschner, K. (1985) · PubMed · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [48]Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG. The Alcohol Use Disorders Test. Guidelines for Use in Primary Care. Second ed. World Health Organization, Department of Mental Health and Substance Dependence.
Cited by
Sorted by citations
Ahmed, M. H., Ahmed, F., Abu-Median, A.-B., Panourgia, M. P., Owles, H., Ochieng, B. M. N., Ahamed, H., Wale, J., Dietsch, B., & Mital, D. (2023) · Microorganisms · doi:10.3390/microorganisms11102426 · Cited by 22 · see citing works
Context, COVID-19 and comorbidities: exploring emergent directions in syndemics and HIV research
Logie, C. H., Coelho, M., Kohrt, B., Tsai, A. C., & Mendenhall, E. (2022) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000722 · Cited by 20 · see citing works
Du, M., Zhang, S., Liu, M., & Liu, J. (2025) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2025.102654 · Cited by 18 · see citing works
The use of biomarkers to guide precision treatment for tobacco use
Siegel, S. D., Tindle, H. A., Bergen, A. W., Tyndale, R. F., & Schnoll, R. A. (2023) · Addiction Neuroscience · doi:10.1016/j.addicn.2023.100076 · Cited by 17 · see citing works
Self-citationCardiovascular Disease Risk Factor Control in People With and Without HIV
Silverberg, M. J., Levine, T., Lea, A. N., Williams, A. E., Alexeeff, S., BRYANT, K. J., Cavassini, M. L., Flamm, J., Hare, C. B., Ingle, S. M., et al. (2024) · Clinical Infectious Diseases · doi:10.1093/cid/ciad728 · Cited by 15 · see citing works
Self-citationSuksatan, W., Teravecharoenchai, S., & Sarayuthpitak, J. (2024) · Journal of Nursing and Midwifery Sciences · doi:10.5812/jnms-144587 · Cited by 12 · see citing works
“Previous research supports our observation that non-smoking status is conducive to healthy behaviors, whereas smoking may significantly increase the risk of cardiovascular diseases, leading to unhealthy behaviors and complications from other conditions (39, 40).”
ResultBeltran‐Najera, I., Mustafa, A. I., Warren, D. R., Salling, Z., Misiura, M. B., Woods, S. P., & Dotson, V. M. (2023) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2023.02.003 · Cited by 6 · see citing works
Recommendations for empirical syndemics analyses: A stepwise methodological guide
Bulled, N. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e38931 · Cited by 6 · see citing works
Chichetto, N. E., Canidate, S. S., Gebru, N. M., McNeely, K. V., Ding, D. D., Hanna, D. B., Parikh, Z., SHOPTAW, S. J., Jones, D. L., Lazar, J., et al. (2024) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2024.112523 · Cited by 6 · see citing works
Self-citationChichetto, N. E., Gebru, N. M., Plankey, M. W., Tindle, H. A., Koethe, J. R., Hanna, D. B., SHOPTAW, S. J., Jones, D. L., Lazar, J., Kizer, J. R., et al. (2023) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2023.110838 · Cited by 5 · see citing works
Self-citationde Granda‐Orive, J. I., Alonso‐Arroyo, A., Padilla, D. E. L., Aleixandre‐Benavent, R., Solano-Reina, S., Riesco, J. A., Rábade, C., Jiménez-Gómez, M., Revuelta-Salgado, F., & Jimenez-Ruiz, C. A. (2024) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2024.2429675 · Cited by 5 · see citing works
Implications of vascular depression for successful cognitive aging in HIV Disease
Mustafa, A. I., Beltran‐Najera, I., Evans, D., Bartlett, A., Dotson, V. M., & Woods, S. P. (2024) · Journal of NeuroVirology · doi:10.1007/s13365-024-01201-2 · Cited by 3 · see citing works
“…and vascular disease may play an important role in SCA in PLWH. Depression is one of the most prevalent neuropsychiatric disorders among PLWH (Chichetto et al. 2021; Dew et al. 1997; Rabkin 2008) and has been associated with greater disease progression and mortality (So-Armah et al. 2020).”
Woolf-King, S. E., Dalton, M. R., Firkey, M., Sheinfil, A., Bucci, V., Estrada, B., Ramos, J., Hahn, J. A., Bricker, J., Gump, B., et al. (2026) · AIDS and Behavior · doi:10.1007/s10461-025-04990-7 · Cited by 1 · see citing works
“One hypothesized reason for the mixed success of alcohol interventions in the HIV literature is an increasingly recognized syndemic of co-occurring unhealthy alcohol use and other mental health-related problems among PWH [20, 21].”
Mena, S. P. Q., Piñeros, J. G., & Cañón-Montañéz, W. (2024) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed9090196 · Cited by 1 · see citing works
Woolf‐King, S. E., Presutti, E., McKenna, O., Hahn, J. A., Abar, B. W., Dahne, J., Gump, B. B., Bendinskas, K. G., & Maisto, S. A. (2025) · Contemporary Clinical Trials · doi:10.1016/j.cct.2025.108130
Bershteyn, A., Zhou, Q., Charles, D. L., Jeetoo, M., Khan, M. R., Justice, A. C., Chichetto, N. E., Marshall, B. D. L., Gordon, A. J., Crystal, S., et al. (2026) · Journal of General Internal Medicine · doi:10.1007/s11606-026-10236-6
Self-citationOverholser, A., Lucas, J., Scott, K. L., Hauschildt, J., Flocke, S. A., Tindle, H. A., Erroba, J., Marino, M., & Bailey, S. R. (2026) · AJPM Focus · doi:10.1016/j.focus.2026.100500
Self-citationDoren, N. V., Silverberg, M. J., Sarovar, V., Levine, T., Lea, A. N., Sterling, S., Palzes, V. A., Chi, F., Kline‐Simon, A. H., Mian, M. N., et al. (2026) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.70398
“…et al. 2011), substance use disorders, sexually transmitted infections (Shuper et al. 2009), obesity (Obry-Roguet et al. 2018), and cardiometabolic disease (Chichetto et al. 2021), all of which are associated with worse HIV outcomes such as higher or uncontrolled viral load (Chichetto et al. 2025).”
Camard, M., Hendou, S., Bitu, M., Mouanga, C., Boufassa, F., Laurans, S., Chenadec, J. L., Plaçais, L., Avettand-Fènoël, V., Meyer, L., et al. (2026) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofag513
Qian, Y., Zhang, Z.-F., Comulada, W. S., Hidalgo, M. A., Lee, S., Friedman, M. R., Palella, F. J., Plankey, M. W., DʼSouza, G., Detels, R., et al. (2026) · AIDS Education and Prevention · doi:10.1521/aeap.2026.38.5.385
- Authors
- Chichetto, N. E., Kundu, S., Freiberg, M. S., Koethe, J. R., Butt, A. A., Crystal, S., So-Armah, K. A., Cook, R. L., Braithwaite, R. S., Justice, A. C., Fiellin, D. A., Khan, M., Bryant, K. J., Gaither, J. R., Barve, S. S., Crothers, K., Bedimo, R. J., Warner, A., Tindle, H. A., & Study, O. B. O. T. V. A. C.
- Affiliations
- Vanderbilt University Medical Center (US)
- VA Tennessee Valley Healthcare System (US)
- VA Pittsburgh Healthcare System (US)
- Rutgers, The State University of New Jersey (US)
- University of Florida Health (US)
- New York University (US)
- Yale University (US)
- National Institute on Alcohol Abuse and Alcoholism (US)
- University of Louisville (US)
- University of Washington (US)
- VA North Texas Health Care System (US)
- University of California, Los Angeles (US)
- Corresponding author
- Chichetto, Natalie E.
- ORCID
- Venue
- AIDS and Behavior
- Published
- 2021-06-08
- Volume
- 25
- Issue
- 9
- Pages
- 2852-2862
- ISSN
- 1090-7165 (ISSN-L)
- 1573-3254
- PMC
- PMC8376776
- OpenAlex
- W3170641577
- Cited by
- 20
- References
- 110
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 7 · 2023: 4 · 2022: 1
- FWCI
- 3.13
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- AIDS and Behavior (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Heart, Lung, and Blood Institute (K12HL143956)
- National Institute on Alcohol Abuse and Alcoholism (U24AA020794, U01AA020790, U01AA02201, U10AA013566, K01AA029042)
- Topics
- Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- syndemic, cardiovascular disease, HIV infection, veterans, unhealthy alcohol use, smoking, depressive symptoms, incident cardiovascular disease, comorbidities, cardiovascular risk factors
- MeSH terms
- Syndemic, Cardiovascular Diseases, Depression, Humans, Prospective Studies, Risk Factors, Smoking, Veterans, Cohort Studies, HIV Infections, Incidence
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
